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Professor

Hayden Homer

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Overview

Background

I graduated with Honours in Medicine from the University of the West Indies, Jamaica, in 1992. In 1997 I relocated to the UK where I specialised in Obstetrics & Gynaecology and was admitted as a Member of the Royal College of Obstetricians & Gynaecologists in 1999. In 2012 I gained dual accreditation as a Subspecialist in Reproductive Medicine & Surgery and was admitted to the European Specialist Register. In 2012, I was appointed Senior Lecturer and Consultant in Reproductive Medicine & Surgery at University College London (UCL) and UCL Hospitals where I was the clinical lead for IVF and Recurrent Miscarriage and the scientific lead for Mammalian Oocyte Research within UCL’s Institute for Women’s Health. In January 2014 I relocated to Australia after being recruited to UNSW through the DVCR’s Strategic Priority Funding Scheme. At UNSW I jointly set up and co-directed UNSW’s first oocyte biology research lab. In January 2016, following a competitive global search, I was appointed to the fully endowed Christopher Chen Chair in Reproductive Medicine at UQ where I currently head the Christopher Chen Oocyte Research Laboratory. Since relocating to Australia I have been awarded Fellowship of the Royal Australian NZ College of Obstetricians & Gynaecologists.

In parallel with clinical activity, I have developed an internationally leading research program investigating oocyte maturation and oocyte quality. My Ph.D was awarded in 2009 from the University of Newcastle-upon-Tyne (UK) and received a Dean’s commendation. My thesis investigated the regulation of chromosome segregation in mouse and human oocytes and was funded by a WellBeing of Women Research Training Fellowship. My post-doctoral research was undertaken at UCL funded by a prestigious Wellcome Trust Clinician Scientist Fellowship ($1.2 million). At UCL, I was one of the principal investigators in the cross-faculty Mammalian Oocyte and Embryo Research Laboratory. In my first 2 years in Australia, I have secured NHMRC funding as CIA worth over $1 million.

I have placed leading papers on oocyte regulation in high impact journals such as Science, Developmental Cell, Genes & Development and Nature Cell Biology all of which have been cited by the Faculty of 1000 Experts. I have received numerous prizes and awards including the highly prestigious Medical Research Society Young Investigator Award (first and only award made to the specialty of O&G in the UK) and was the first of the UK Walport Clinical Lecturers in all specialties to attain Clinician Scientist status. I was one of the very few to have delivered the RCOG’s William Blair Bell Memorial Lecture whilst still a clinical trainee.

Availability

Professor Hayden Homer is:
Available for supervision

Qualifications

  • Bachelor (Honours) of Medicine Surgery, Newcastle University
  • Doctor of Philosophy, Newcastle University
  • Royal Australian and New Zealand College of Obstetricians and Gynaecologists, Royal Australian and New Zealand College of Obstetricians and Gynaecologists
  • Royal College of Obstetricians and Gynaecologists, Royal College of Obstetricians and Gynaecologists

Works

Search Professor Hayden Homer’s works on UQ eSpace

69 works between 1998 and 2024

21 - 40 of 69 works

2020

Journal Article

The 2019 PGDIS position statement on transfer of mosaic embryos within a context of new information on PGT-A

Gleicher, N., Albertini, D. F., Barad, D. H., Homer, H., Modi, D., Murtinger, M., Patrizio, P., Orvieto, R., Takahashi, S., Weghofer, A., Ziebe, S., Noyes, N. and for the International Do No Harm Group in IVF (IDNHG-IVF) (2020). The 2019 PGDIS position statement on transfer of mosaic embryos within a context of new information on PGT-A. Reproductive Biology and Endocrinology, 18 (1) 57. doi: 10.1186/s12958-020-00616-w

The 2019 PGDIS position statement on transfer of mosaic embryos within a context of new information on PGT-A

2020

Journal Article

Oocytes mount a noncanonical DNA damage response involving APC-Cdh1–mediated proteolysis

Subramanian, Goutham Narayanan, Greaney, Jessica, Wei, Zhe, Becherel, Olivier, Lavin, Martin and Homer, Hayden Anthony (2020). Oocytes mount a noncanonical DNA damage response involving APC-Cdh1–mediated proteolysis. Journal of Cell Biology, 219 (4) e201907213. doi: 10.1083/jcb.201907213

Oocytes mount a noncanonical DNA damage response involving APC-Cdh1–mediated proteolysis

2020

Journal Article

Sirt3 is dispensable for oocyte quality and female fertility in lean and obese mice

Iljas, Juvita D. and Homer, Hayden A. (2020). Sirt3 is dispensable for oocyte quality and female fertility in lean and obese mice. FASEB Journal, 34 (5), 6641-6653. doi: 10.1096/fj.202000153R

Sirt3 is dispensable for oocyte quality and female fertility in lean and obese mice

2020

Journal Article

NAD+ repletion rescues female fertility during reproductive aging

Bertoldo, Michael J., Listijono, Dave R., Ho, Wing-Hong Jonathan, Riepsamen, Angelique H., Goss, Dale M., Richani, Dulama, Jin, Xing L., Mahbub, Saabah, Campbell, Jared M., Habibalahi, Abbas, Loh, Wei-Guo Nicholas, Youngson, Neil A., Maniam, Jayanthi, Wong, Ashley S.A., Selesniemi, Kaisa, Bustamante, Sonia, Li, Catherine, Zhao, Yiqing, Marinova, Maria B., Kim, Lynn-Jee, Lau, Laurin, Wu, Rachael M., Mikolaizak, A. Stefanie, Araki, Toshiyuki, Le Couteur, David G., Turner, Nigel, Morris, Margaret J., Walters, Kirsty A., Goldys, Ewa ... Wu, Lindsay E. (2020). NAD+ repletion rescues female fertility during reproductive aging. Cell Reports, 30 (6), 1670-1681.e7. doi: 10.1016/j.celrep.2020.01.058

NAD+ repletion rescues female fertility during reproductive aging

2020

Journal Article

Reporting IVF outcomes: the devil is in the detail

Homer, Hayden Anthony (2020). Reporting IVF outcomes: the devil is in the detail. Australian and New Zealand Journal of Obstetrics and Gynaecology, 60 (1), 11-14. doi: 10.1111/ajo.13118

Reporting IVF outcomes: the devil is in the detail

2020

Journal Article

The presence of immature GV− stage oocytes during IVF/ICSI is a marker of poor oocyte quality: a pilot study

Astbury, Pia, Subramanian, Goutham N., Greaney, Jessica, Roling, Chris, Irving, Jacqui and Homer, Hayden A. (2020). The presence of immature GV− stage oocytes during IVF/ICSI is a marker of poor oocyte quality: a pilot study. Medical Sciences, 8 (1), 4. doi: 10.3390/medsci8010004

The presence of immature GV− stage oocytes during IVF/ICSI is a marker of poor oocyte quality: a pilot study

2020

Journal Article

The role of oocyte quality in explaining “unexplained” infertility

Homer, Hayden Anthony (2020). The role of oocyte quality in explaining “unexplained” infertility. Seminars in Reproductive Medicine, 38 (01), 21-28. doi: 10.1055/s-0040-1721377

The role of oocyte quality in explaining “unexplained” infertility

2019

Journal Article

First meiotic anaphase requires Cep55-dependent inhibitory cyclin-dependent kinase 1 phosphorylation

Zhou, Chenxi, Hancock, Janelle L., Khanna, Kum Kum and Homer, Hayden A. (2019). First meiotic anaphase requires Cep55-dependent inhibitory cyclin-dependent kinase 1 phosphorylation. Journal of Cell Science, 132 (18) jcs233379, jcs233379. doi: 10.1242/jcs.233379

First meiotic anaphase requires Cep55-dependent inhibitory cyclin-dependent kinase 1 phosphorylation

2019

Journal Article

A review of first line infertility treatments and supporting evidence in women with polycystic ovary syndrome

Costello, Michael, Garad, Rhonda, Hart, Roger, Homer, Hayden, Johnson, Louise, Jordan, Cailin, Mocanu, Edgar, Qiao, Jie, Rombauts, Luk, Teede, Helena J., Vanky, Eszter, Venetis, Christos and Ledger, William (2019). A review of first line infertility treatments and supporting evidence in women with polycystic ovary syndrome. Medical Sciences, 7 (9) 95, 1-10. doi: 10.3390/medsci7090095

A review of first line infertility treatments and supporting evidence in women with polycystic ovary syndrome

2019

Conference Publication

Disruption of spermatogenesis and infertility in Ataxia with Oculomotor Apraxia Type 2 (AOA2)

Fogel, Brent, Becherel, Olivier, Zeitlin, Scott, Samaratunga, Hemamali, Greaney, Jessica, Homer, Hayden and Lavin, Martin (2019). Disruption of spermatogenesis and infertility in Ataxia with Oculomotor Apraxia Type 2 (AOA2). 71st Annual Meeting of the American-Academy-of-Neurology (AAN), Philadelphia, PA, United States, 4-10 May 2019. Philadelphia, PA, United States: Lippincott Williams & Wilkins.

Disruption of spermatogenesis and infertility in Ataxia with Oculomotor Apraxia Type 2 (AOA2)

2019

Conference Publication

Disruption of spermatogenesis and infertility in Ataxia with Oculomotor Apraxia Type 2 (AOA2)

Fogel, Brent, Becherel, Olivier, Zeitlin, Scott, Samaratunga, Hemamali, Greaney, Jessica, Homer, Hayden and Lavin, Martin (2019). Disruption of spermatogenesis and infertility in Ataxia with Oculomotor Apraxia Type 2 (AOA2). AAN 71st Annual Meeting, Philadelphia, PA United States, 4-10 May 2019. Philadelphia, PA United States: Wolters Kluwer. doi: 10.1212/wnl.92.15_supplement.p4.7-003

Disruption of spermatogenesis and infertility in Ataxia with Oculomotor Apraxia Type 2 (AOA2)

2019

Journal Article

Preimplantation genetic testing for aneuploidy (PGT-A): the biology, the technology and the clinical outcomes

Homer, Hayden Anthony (2019). Preimplantation genetic testing for aneuploidy (PGT-A): the biology, the technology and the clinical outcomes. Australian and New Zealand Journal of Obstetrics and Gynaecology, 59 (2), 317-324. doi: 10.1111/ajo.12960

Preimplantation genetic testing for aneuploidy (PGT-A): the biology, the technology and the clinical outcomes

2019

Journal Article

Disruption of spermatogenesis and infertility in Ataxia with Oculomotor Apraxia Type 2 (AOA2)

Becherel, Olivier J., Fogel, Brent L., Zeitlin, Scott I., Samaratunga, Hemamali, Greaney, Jessica, Homer, Hayden and Lavin, Martin F. (2019). Disruption of spermatogenesis and infertility in Ataxia with Oculomotor Apraxia Type 2 (AOA2). Cerebellum, 18 (3), 448-456. doi: 10.1007/s12311-019-01012-w

Disruption of spermatogenesis and infertility in Ataxia with Oculomotor Apraxia Type 2 (AOA2)

2018

Journal Article

Modern management of recurrent miscarriage

Homer, Hayden Anthony (2018). Modern management of recurrent miscarriage. Australian and New Zealand Journal of Obstetrics and Gynaecology, 59 (1), 36-44. doi: 10.1111/ajo.12920

Modern management of recurrent miscarriage

2018

Journal Article

Cdk1 inactivation induces post-anaphase-onset spindle migration and membrane protrusion required for extreme asymmetry in mouse oocytes

Wei, Zhe, Greaney, Jessica, Zhou, Chenxi and A. Homer, Hayden (2018). Cdk1 inactivation induces post-anaphase-onset spindle migration and membrane protrusion required for extreme asymmetry in mouse oocytes. Nature Communications, 9 (1) 4029, 4029. doi: 10.1038/s41467-018-06510-9

Cdk1 inactivation induces post-anaphase-onset spindle migration and membrane protrusion required for extreme asymmetry in mouse oocytes

2018

Book Chapter

Immunofluorescence staining of K-fibers in mouse oocytes using cold fixation

Greaney, Jessica, Wei, Zhe and Homer, Hayden (2018). Immunofluorescence staining of K-fibers in mouse oocytes using cold fixation. Mouse oocyte development: methods and protocols. (pp. 77-87) edited by Marie-Hélène Verlhac and Marie-Emilie Terret. New York, NY, United States: Humana Press. doi: 10.1007/978-1-4939-8603-3_9

Immunofluorescence staining of K-fibers in mouse oocytes using cold fixation

2017

Journal Article

Regulation of chromosome segregation in oocytes and the cellular basis for female meiotic errors

Greaney, Jessica, Wei, Zhe and Homer, Hayden (2017). Regulation of chromosome segregation in oocytes and the cellular basis for female meiotic errors. Human Reproduction Update, 24 (2), 135-161. doi: 10.1093/humupd/dmx035

Regulation of chromosome segregation in oocytes and the cellular basis for female meiotic errors

2017

Journal Article

Embryo- and endometrium-derived exosomes and their potential role in assisted reproductive treatments-liquid biopsies for endometrial receptivity

Homer, Hayden, Rice, Gregory E. and Salomon, Carlos (2017). Embryo- and endometrium-derived exosomes and their potential role in assisted reproductive treatments-liquid biopsies for endometrial receptivity. Placenta, 54, 89-94. doi: 10.1016/j.placenta.2016.12.011

Embryo- and endometrium-derived exosomes and their potential role in assisted reproductive treatments-liquid biopsies for endometrial receptivity

2017

Conference Publication

Sirtuin-mediated regulation of oocyte quality

Homer, Hayden (2017). Sirtuin-mediated regulation of oocyte quality. ESA-SRB-ANZBMS 2016 , Gold Coast Convention and Exhibition Centre, Gold Coast, Queensland, Australia, 21-24 August 2016. Chichester, West Sussex, United Kingdom : Wiley-Blackwell.

Sirtuin-mediated regulation of oocyte quality

2017

Conference Publication

Characterization of embryo-derived exosomal miRNAs: implications on endometrial receptivity.

Homer, Hayden, Yazdani, Anusch, Rice, Gregory E. and Salomon, Carlos (2017). Characterization of embryo-derived exosomal miRNAs: implications on endometrial receptivity.. 64th Annual Scientific Meeting of the Society for Reproductive Investigation (SRI), Orlando, FL, United States, 15-18 March 2017. Thousand Oaks, CA, United States: Sage Publications.

Characterization of embryo-derived exosomal miRNAs: implications on endometrial receptivity.

Funding

Current funding

  • 2023 - 2026
    A novel approach to reducing the psychosocial burden of infertility treatment
    NHMRC IDEAS Grants
    Open grant
  • 2023 - 2026
    Characterization and validation of a new mouse model of spontaneous endometriosis to implement translation of basic research to the clinic
    United States Congressionally Directed Medical Research Programs - Peer Reviewed Medical Research Program
    Open grant

Past funding

  • 2017 - 2018
    Chlamydia infiection in the ovary: effects on fertility in female koalas
    Annandale Bequest
    Open grant
  • 2017 - 2021
    Nicotinamide adenine dinucleotide (NAD+)-raising agents for improving oocyte quality
    NHMRC Development Grant
    Open grant
  • 2016 - 2018
    Female reproductive health preservation by Nictotinamide Adenine Dinucleotide (NAD+) and Sirtuin2 (SIRT2)
    NHMRC Project Grant
    Open grant
  • 2015 - 2018
    A BubR1-centred network for non-invasively measuring human oocyte quality
    NHMRC Project Grant
    Open grant

Supervision

Availability

Professor Hayden Homer is:
Available for supervision

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Supervision history

Completed supervision

Media

Enquiries

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