Overview
Background
I graduated with Honours in Medicine from the University of the West Indies, Jamaica, in 1992. In 1997 I relocated to the UK where I specialised in Obstetrics & Gynaecology and was admitted as a Member of the Royal College of Obstetricians & Gynaecologists in 1999. In 2012 I gained dual accreditation as a Subspecialist in Reproductive Medicine & Surgery and was admitted to the European Specialist Register. In 2012, I was appointed Senior Lecturer and Consultant in Reproductive Medicine & Surgery at University College London (UCL) and UCL Hospitals where I was the clinical lead for IVF and Recurrent Miscarriage and the scientific lead for Mammalian Oocyte Research within UCL’s Institute for Women’s Health. In January 2014 I relocated to Australia after being recruited to UNSW through the DVCR’s Strategic Priority Funding Scheme. At UNSW I jointly set up and co-directed UNSW’s first oocyte biology research lab. In January 2016, following a competitive global search, I was appointed to the fully endowed Christopher Chen Chair in Reproductive Medicine at UQ where I currently head the Christopher Chen Oocyte Research Laboratory. Since relocating to Australia I have been awarded Fellowship of the Royal Australian NZ College of Obstetricians & Gynaecologists.
In parallel with clinical activity, I have developed an internationally leading research program investigating oocyte maturation and oocyte quality. My Ph.D was awarded in 2009 from the University of Newcastle-upon-Tyne (UK) and received a Dean’s commendation. My thesis investigated the regulation of chromosome segregation in mouse and human oocytes and was funded by a WellBeing of Women Research Training Fellowship. My post-doctoral research was undertaken at UCL funded by a prestigious Wellcome Trust Clinician Scientist Fellowship ($1.2 million). At UCL, I was one of the principal investigators in the cross-faculty Mammalian Oocyte and Embryo Research Laboratory. In my first 2 years in Australia, I have secured NHMRC funding as CIA worth over $1 million.
I have placed leading papers on oocyte regulation in high impact journals such as Science, Developmental Cell, Genes & Development and Nature Cell Biology all of which have been cited by the Faculty of 1000 Experts. I have received numerous prizes and awards including the highly prestigious Medical Research Society Young Investigator Award (first and only award made to the specialty of O&G in the UK) and was the first of the UK Walport Clinical Lecturers in all specialties to attain Clinician Scientist status. I was one of the very few to have delivered the RCOG’s William Blair Bell Memorial Lecture whilst still a clinical trainee.
Availability
- Professor Hayden Homer is:
- Available for supervision
Fields of research
Qualifications
- Bachelor (Honours) of Medicine Surgery, Newcastle University
- Doctor of Philosophy, Newcastle University
- Royal Australian and New Zealand College of Obstetricians and Gynaecologists, Royal Australian and New Zealand College of Obstetricians and Gynaecologists
- Royal College of Obstetricians and Gynaecologists, Royal College of Obstetricians and Gynaecologists
Works
Search Professor Hayden Homer’s works on UQ eSpace
2020
Journal Article
The 2019 PGDIS position statement on transfer of mosaic embryos within a context of new information on PGT-A
Gleicher, N., Albertini, D. F., Barad, D. H., Homer, H., Modi, D., Murtinger, M., Patrizio, P., Orvieto, R., Takahashi, S., Weghofer, A., Ziebe, S., Noyes, N. and for the International Do No Harm Group in IVF (IDNHG-IVF) (2020). The 2019 PGDIS position statement on transfer of mosaic embryos within a context of new information on PGT-A. Reproductive Biology and Endocrinology, 18 (1) 57. doi: 10.1186/s12958-020-00616-w
2020
Journal Article
Oocytes mount a noncanonical DNA damage response involving APC-Cdh1–mediated proteolysis
Subramanian, Goutham Narayanan, Greaney, Jessica, Wei, Zhe, Becherel, Olivier, Lavin, Martin and Homer, Hayden Anthony (2020). Oocytes mount a noncanonical DNA damage response involving APC-Cdh1–mediated proteolysis. Journal of Cell Biology, 219 (4) e201907213. doi: 10.1083/jcb.201907213
2020
Journal Article
Sirt3 is dispensable for oocyte quality and female fertility in lean and obese mice
Iljas, Juvita D. and Homer, Hayden A. (2020). Sirt3 is dispensable for oocyte quality and female fertility in lean and obese mice. FASEB Journal, 34 (5), 6641-6653. doi: 10.1096/fj.202000153R
2020
Journal Article
NAD+ repletion rescues female fertility during reproductive aging
Bertoldo, Michael J., Listijono, Dave R., Ho, Wing-Hong Jonathan, Riepsamen, Angelique H., Goss, Dale M., Richani, Dulama, Jin, Xing L., Mahbub, Saabah, Campbell, Jared M., Habibalahi, Abbas, Loh, Wei-Guo Nicholas, Youngson, Neil A., Maniam, Jayanthi, Wong, Ashley S.A., Selesniemi, Kaisa, Bustamante, Sonia, Li, Catherine, Zhao, Yiqing, Marinova, Maria B., Kim, Lynn-Jee, Lau, Laurin, Wu, Rachael M., Mikolaizak, A. Stefanie, Araki, Toshiyuki, Le Couteur, David G., Turner, Nigel, Morris, Margaret J., Walters, Kirsty A., Goldys, Ewa ... Wu, Lindsay E. (2020). NAD+ repletion rescues female fertility during reproductive aging. Cell Reports, 30 (6), 1670-1681.e7. doi: 10.1016/j.celrep.2020.01.058
2020
Journal Article
Reporting IVF outcomes: the devil is in the detail
Homer, Hayden Anthony (2020). Reporting IVF outcomes: the devil is in the detail. Australian and New Zealand Journal of Obstetrics and Gynaecology, 60 (1), 11-14. doi: 10.1111/ajo.13118
2020
Journal Article
The presence of immature GV− stage oocytes during IVF/ICSI is a marker of poor oocyte quality: a pilot study
Astbury, Pia, Subramanian, Goutham N., Greaney, Jessica, Roling, Chris, Irving, Jacqui and Homer, Hayden A. (2020). The presence of immature GV− stage oocytes during IVF/ICSI is a marker of poor oocyte quality: a pilot study. Medical Sciences, 8 (1), 4. doi: 10.3390/medsci8010004
2020
Journal Article
The role of oocyte quality in explaining “unexplained” infertility
Homer, Hayden Anthony (2020). The role of oocyte quality in explaining “unexplained” infertility. Seminars in Reproductive Medicine, 38 (01), 21-28. doi: 10.1055/s-0040-1721377
2019
Journal Article
First meiotic anaphase requires Cep55-dependent inhibitory cyclin-dependent kinase 1 phosphorylation
Zhou, Chenxi, Hancock, Janelle L., Khanna, Kum Kum and Homer, Hayden A. (2019). First meiotic anaphase requires Cep55-dependent inhibitory cyclin-dependent kinase 1 phosphorylation. Journal of Cell Science, 132 (18) jcs233379, jcs233379. doi: 10.1242/jcs.233379
2019
Journal Article
A review of first line infertility treatments and supporting evidence in women with polycystic ovary syndrome
Costello, Michael, Garad, Rhonda, Hart, Roger, Homer, Hayden, Johnson, Louise, Jordan, Cailin, Mocanu, Edgar, Qiao, Jie, Rombauts, Luk, Teede, Helena J., Vanky, Eszter, Venetis, Christos and Ledger, William (2019). A review of first line infertility treatments and supporting evidence in women with polycystic ovary syndrome. Medical Sciences, 7 (9) 95, 1-10. doi: 10.3390/medsci7090095
2019
Conference Publication
Disruption of spermatogenesis and infertility in Ataxia with Oculomotor Apraxia Type 2 (AOA2)
Fogel, Brent, Becherel, Olivier, Zeitlin, Scott, Samaratunga, Hemamali, Greaney, Jessica, Homer, Hayden and Lavin, Martin (2019). Disruption of spermatogenesis and infertility in Ataxia with Oculomotor Apraxia Type 2 (AOA2). 71st Annual Meeting of the American-Academy-of-Neurology (AAN), Philadelphia, PA, United States, 4-10 May 2019. Philadelphia, PA, United States: Lippincott Williams & Wilkins.
2019
Conference Publication
Disruption of spermatogenesis and infertility in Ataxia with Oculomotor Apraxia Type 2 (AOA2)
Fogel, Brent, Becherel, Olivier, Zeitlin, Scott, Samaratunga, Hemamali, Greaney, Jessica, Homer, Hayden and Lavin, Martin (2019). Disruption of spermatogenesis and infertility in Ataxia with Oculomotor Apraxia Type 2 (AOA2). AAN 71st Annual Meeting, Philadelphia, PA United States, 4-10 May 2019. Philadelphia, PA United States: Wolters Kluwer. doi: 10.1212/wnl.92.15_supplement.p4.7-003
2019
Journal Article
Preimplantation genetic testing for aneuploidy (PGT-A): the biology, the technology and the clinical outcomes
Homer, Hayden Anthony (2019). Preimplantation genetic testing for aneuploidy (PGT-A): the biology, the technology and the clinical outcomes. Australian and New Zealand Journal of Obstetrics and Gynaecology, 59 (2), 317-324. doi: 10.1111/ajo.12960
2019
Journal Article
Disruption of spermatogenesis and infertility in Ataxia with Oculomotor Apraxia Type 2 (AOA2)
Becherel, Olivier J., Fogel, Brent L., Zeitlin, Scott I., Samaratunga, Hemamali, Greaney, Jessica, Homer, Hayden and Lavin, Martin F. (2019). Disruption of spermatogenesis and infertility in Ataxia with Oculomotor Apraxia Type 2 (AOA2). Cerebellum, 18 (3), 448-456. doi: 10.1007/s12311-019-01012-w
2018
Journal Article
Modern management of recurrent miscarriage
Homer, Hayden Anthony (2018). Modern management of recurrent miscarriage. Australian and New Zealand Journal of Obstetrics and Gynaecology, 59 (1), 36-44. doi: 10.1111/ajo.12920
2018
Journal Article
Cdk1 inactivation induces post-anaphase-onset spindle migration and membrane protrusion required for extreme asymmetry in mouse oocytes
Wei, Zhe, Greaney, Jessica, Zhou, Chenxi and A. Homer, Hayden (2018). Cdk1 inactivation induces post-anaphase-onset spindle migration and membrane protrusion required for extreme asymmetry in mouse oocytes. Nature Communications, 9 (1) 4029, 4029. doi: 10.1038/s41467-018-06510-9
2018
Book Chapter
Immunofluorescence staining of K-fibers in mouse oocytes using cold fixation
Greaney, Jessica, Wei, Zhe and Homer, Hayden (2018). Immunofluorescence staining of K-fibers in mouse oocytes using cold fixation. Mouse oocyte development: methods and protocols. (pp. 77-87) edited by Marie-Hélène Verlhac and Marie-Emilie Terret. New York, NY, United States: Humana Press. doi: 10.1007/978-1-4939-8603-3_9
2017
Journal Article
Regulation of chromosome segregation in oocytes and the cellular basis for female meiotic errors
Greaney, Jessica, Wei, Zhe and Homer, Hayden (2017). Regulation of chromosome segregation in oocytes and the cellular basis for female meiotic errors. Human Reproduction Update, 24 (2), 135-161. doi: 10.1093/humupd/dmx035
2017
Journal Article
Embryo- and endometrium-derived exosomes and their potential role in assisted reproductive treatments-liquid biopsies for endometrial receptivity
Homer, Hayden, Rice, Gregory E. and Salomon, Carlos (2017). Embryo- and endometrium-derived exosomes and their potential role in assisted reproductive treatments-liquid biopsies for endometrial receptivity. Placenta, 54, 89-94. doi: 10.1016/j.placenta.2016.12.011
2017
Conference Publication
Sirtuin-mediated regulation of oocyte quality
Homer, Hayden (2017). Sirtuin-mediated regulation of oocyte quality. ESA-SRB-ANZBMS 2016 , Gold Coast Convention and Exhibition Centre, Gold Coast, Queensland, Australia, 21-24 August 2016. Chichester, West Sussex, United Kingdom : Wiley-Blackwell.
2017
Conference Publication
Characterization of embryo-derived exosomal miRNAs: implications on endometrial receptivity.
Homer, Hayden, Yazdani, Anusch, Rice, Gregory E. and Salomon, Carlos (2017). Characterization of embryo-derived exosomal miRNAs: implications on endometrial receptivity.. 64th Annual Scientific Meeting of the Society for Reproductive Investigation (SRI), Orlando, FL, United States, 15-18 March 2017. Thousand Oaks, CA, United States: Sage Publications.
Funding
Current funding
Past funding
Supervision
Availability
- Professor Hayden Homer is:
- Available for supervision
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Supervision history
Completed supervision
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2020
Doctor Philosophy
Role of nucleic acid binding proteins in oocyte development and female fertility
Principal Advisor
Other advisors: Honorary Professor Kum Kum Khanna
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2020
Doctor Philosophy
The in vivo roles of Sirtuin 1 and 3 in age- and obesity-related decline in female fertility
Principal Advisor
Other advisors: Professor Carlos Salomon Gallo
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2020
Doctor Philosophy
Asymmetric Cell Division in Mammalian Oocytes
Principal Advisor
Other advisors: Professor Carlos Salomon Gallo
Media
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