Overview
Background
Dr François-René Bertin (DVM, MS, PhD, dipl.ACVIM (LAIM)) is an equine internist with expertise in clinical endocrinology.
François-René completed a Doctorate of Veterinary Medicine (University of Nantes, France), an American College of Veterinary Internal Medicine (ACVIM) residency in equine internal medicine (Purdue University, USA) and a PhD in physiology (McGill University, Canada). He moved to the School of Veterinary Science at UQ in 2016.
François-René’s research interests lie in the pathophysiology of hyperinsulinaemia-associated laminitis and the disorders of the equine hypothalamo-pituitary adrenocortical axis. Some of his current projects examine the regulators of pancreatic b-cell activity and the mechanisms of pituitary gland senescence. François-René has received awards from the School of Veterinary Science and the Faculty of Science for his contribution to Research and HDR student supervision.
François-René teaches equine internal medicine into the veterinary science and veterinary technology programs and coordinates the Equine Clinical Studies course. He has received Teaching and Learning Faculty Awards.
Availability
- Associate Professor François-René Bertin is:
- Available for supervision
- Media expert
Fields of research
Qualifications
- Doctoral Diploma of Veterinary Medicine, Université de Nantes
- Masters (Coursework) of Science, Purdue University
- Doctor of Philosophy, McGill University
- Fellow, American College of Veterinary Internal Medicine, American College of Veterinary Internal Medicine
Research interests
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Equine endocrinology
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Pancreatic b-cell activity
Understanding the mechanisms associated with hyperinsulinaemia and the development of equine laminitis.
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Hypothalamo-pituitary adrenocortical axis senescence
Understanding the age-associated changes of the equine pituitary gland.
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Clinical diagnostic testing
Improving diagnostic testing of endocrine disorders in horses.
Works
Search Professor François-René Bertin’s works on UQ eSpace
Featured
2020
Journal Article
Clinical implications of using adrenocorticotropic hormone diagnostic cutoffs or reference intervals to diagnose pituitary pars intermedia dysfunction in mature horses
Horn, Remona, Stewart, Allison J., Jackson, Karen V., Dryburgh, Elizabeth L., Medina‐Torres, Carlos E. and Bertin, François‐René (2020). Clinical implications of using adrenocorticotropic hormone diagnostic cutoffs or reference intervals to diagnose pituitary pars intermedia dysfunction in mature horses. Journal of Veterinary Internal Medicine, 35 (1) jvim.16017, 560-570. doi: 10.1111/jvim.16017
Featured
2020
Book Chapter
Endocrine system
Kritchevsky, Janice E. and Bertin, François-René (2020). Endocrine system. Equine clinical medicine, surgery and reproduction. (pp. 901-922) edited by Munroe, Graham A.. Boca Raton, FL, United States: CRC Press Taylor & Francis Group.
Featured
2020
Book
Equine endocrinology
Bertin, F. R. and Fraser, N. S. (2020). Equine endocrinology. Wallingford, United Kingdom: CABI. doi: 10.1079/9781789241099.0000
Featured
2018
Journal Article
Factors associated with survival, laminitis and insulin dysregulation in horses diagnosed with equine pituitary pars intermedia dysfunction
Horn, R., Bamford, N. J., Afonso, T., Sutherland, M., Buckerfield, J., Tan, R. H. H., Secombe, C. J., Stewart, A. J. and Bertin, F. R. (2018). Factors associated with survival, laminitis and insulin dysregulation in horses diagnosed with equine pituitary pars intermedia dysfunction. Equine Veterinary Journal, 51 (4), 440-445. doi: 10.1111/evj.13041
Featured
2017
Journal Article
The diagnosis of equine insulin dysregulation
Bertin, F. R. and de Laat, M. A. (2017). The diagnosis of equine insulin dysregulation. Equine Veterinary Journal, 49 (5), 570-576. doi: 10.1111/evj.12703
Featured
2013
Journal Article
Comparison of a two-step insulin-response test to conventional insulin-sensitivity testing in horses
Bertin, F. R. and Sojka-Kritchevsky, J. E. (2013). Comparison of a two-step insulin-response test to conventional insulin-sensitivity testing in horses. Domestic Animal Endocrinology, 44 (1), 19-25. doi: 10.1016/j.domaniend.2012.07.003
2024
Journal Article
Pergolide mesylate administration does not decrease blood thyroid hormone concentrations and thyroid function in horses
Jargielo, Martyna M., Kritchevsky, Janice E. and Bertin, François-René (2024). Pergolide mesylate administration does not decrease blood thyroid hormone concentrations and thyroid function in horses. American Journal of Veterinary Research, 1-5. doi: 10.2460/ajvr.24.09.0257
2024
Journal Article
Effect of phenylbutazone administration on the enteroinsular axis in horses with insulin dysregulation
Kemp, Kate L., Skinner, Jazmine E. and Bertin, François‐René (2024). Effect of phenylbutazone administration on the enteroinsular axis in horses with insulin dysregulation. Journal of Veterinary Internal Medicine, 39 (1) e17256, e17256. doi: 10.1111/jvim.17256
2024
Journal Article
Value of measuring markers of lipid metabolism in horses during an oral glucose test
Zemek, Claire H. K., Kemp, Kate L. and Bertin, François‐René (2024). Value of measuring markers of lipid metabolism in horses during an oral glucose test. Journal of Veterinary Internal Medicine, 38 (6), 3309-3314. doi: 10.1111/jvim.17199
2024
Journal Article
Extracellular RNA Induces Neutrophil Recruitment Via Toll‐Like Receptor 3 During Venous Thrombosis After Vascular Injury
Najem, Maria Y., Rys, Ryan N., Laurance, Sandrine, Bertin, François‐René, Gourdou‐Latyszenok, Virginie, Gourhant, Lénaïck, Le Gall, Lauriane, Le Corre, Rozenn, Couturaud, Francis, Blostein, Mark D. and Lemarié, Catherine A. (2024). Extracellular RNA Induces Neutrophil Recruitment Via Toll‐Like Receptor 3 During Venous Thrombosis After Vascular Injury. Journal of the American Heart Association, 13 (15) ARTN e034492, e034492. doi: 10.1161/jaha.124.034492
2024
Conference Publication
Influence of breed, season and pituitary intermedia dysfunction on plasma B-endorphin concentrations in horses and ponies
Bamford, Nicholas, Stewart, Allison J., El-Hage, Charles, Bertin, François-René and Bailey, Simon (2024). Influence of breed, season and pituitary intermedia dysfunction on plasma B-endorphin concentrations in horses and ponies. Australian Veterinary Association Conference, Melbourne, VIC Australia, 27-30 May 2024.
2024
Journal Article
Effect of phenylbutazone on insulin secretion in horses with insulin dysregulation
Kemp, Kate L., Skinner, Jazmine E. and Bertin, François‐René (2024). Effect of phenylbutazone on insulin secretion in horses with insulin dysregulation. Journal of Veterinary Internal Medicine, 38 (2), 1177-1184. doi: 10.1111/jvim.17013
2024
Book
Concise textbook of equine clinical practice book 5 : Nervous system, eyes, cardiovascular disorders and haemolymphatic system
Beasley, Erin, Munroe, Graham, Bertin, François-René and Munroe, Graham (2024). Concise textbook of equine clinical practice book 5 : Nervous system, eyes, cardiovascular disorders and haemolymphatic system. Boca Raton, FL United States: CRC Press. doi: 10.1201/9781003451921
2024
Journal Article
Epidemiological investigation of insulin dysregulation in Shetland and Welsh ponies in Australia
Clark, Brianna L., Norton, Elaine M., Bamford, Nicholas J., Randhawa, Imtiaz A. S., Kemp, Kate L., McCue, Molly E., Bertin, François‐René and Stewart, Allison J. (2024). Epidemiological investigation of insulin dysregulation in Shetland and Welsh ponies in Australia. Equine Veterinary Journal, 56 (2), 281-290. doi: 10.1111/evj.14044
2023
Book
Concise textbook of equine clinical practice book 4: Liver, endocrine, urinary, skin and wounds
Munroe, Graham, Bertin, François-René, Cruz, Antonio, Durham, Andy and Knottenbelt, Derek (2023). Concise textbook of equine clinical practice book 4: Liver, endocrine, urinary, skin and wounds. Boca Raton, FL United States: CRC Press. doi: 10.1201/9781003453666
2023
Journal Article
Lipid disorders in horses and foals
Bertin, François-René (2023). Lipid disorders in horses and foals. UK-Vet Equine, 7 (6), 248-253. doi: 10.12968/ukve.2023.7.6.248
2023
Journal Article
Clinical implications of imprecise sampling time for 10‐ and 30‐min thyrotropin‐releasing hormone stimulation tests in horses
Vorster, Dante M., Wang, Wenqing, Kemp, Kate L., Bamford, Nicholas J. and Bertin, François‐René (2023). Clinical implications of imprecise sampling time for 10‐ and 30‐min thyrotropin‐releasing hormone stimulation tests in horses. Equine Veterinary Journal, 56 (2), 291-298. doi: 10.1111/evj.13991
2023
Journal Article
Diagnosis and management of thyroid disorders and thyroid hormone supplementation in adult horses and foals
Bertin, François-René, Frank, Nicholas, Breuhaus, Babetta A., Schott, Harold C. and Kritchevsky, Janice E. (2023). Diagnosis and management of thyroid disorders and thyroid hormone supplementation in adult horses and foals. Equine Veterinary Journal, 56 (2), 243-252. doi: 10.1111/evj.13981
2023
Journal Article
Evaluation of field-testing protocols to diagnose insulin dysregulation in ponies using a Bayesian approach
Clark, B. L., Stewart, A. J., Kemp, K. L., Bamford, N. J. and Bertin, F.-R. (2023). Evaluation of field-testing protocols to diagnose insulin dysregulation in ponies using a Bayesian approach. The Veterinary Journal, 298-299 106019, 106019. doi: 10.1016/j.tvjl.2023.106019
2023
Conference Publication
Breed differences in plasma adrenocorticotropic hormone concentrations among healthy horses and ponies
Bamford, Nicholas J., Stewart, Allison J., El-Hage, Charlie M., Bertin, Francois-Rene and Bailey, Simon R. (2023). Breed differences in plasma adrenocorticotropic hormone concentrations among healthy horses and ponies. Australian and New Zealand College of Veterinary Scientists, Gold Coast, QLD, Australia, 27-29 July 2023.
Funding
Current funding
Supervision
Availability
- Associate Professor François-René Bertin is:
- Available for supervision
Before you email them, read our advice on how to contact a supervisor.
Available projects
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Insulin dysregulation
Insulin dysregulation is the hallmark of equine metabolic syndrome and has received attention because of its direct association with laminitis. In the absence of an adequate treatment for laminitis, our research focuses on the mechanisms leading to laminitis as well as on the early detection of individuals at risk of developing laminitis.
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Hypothalamus-pituitary-adrenal dysfunctions
The hypothalamo-pituitary-adrenal axis is a major regulator of homeostasis. With sickness or with age, this axis can be dysregulated leading to critical illness-related corticosteroid insufficiency or to pituitary pars intermedia dysfunction (PPID) respectively. The latter is a common condition of older horses that can result in laminitis and our research focuses on the detection and management of horses developping PPID.
Supervision history
Current supervision
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Doctor Philosophy
The role of dopamine in the regulation of gastrointestinal health in horses with pituitary pars intermedia dysfunction.
Principal Advisor
Other advisors: Dr Justine Gibson, Dr Deirdre Mikkelsen, Dr Viviana Gonzalez Astudillo, Dr Allison Stewart
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Doctor Philosophy
Investigating insulin and glucose dynamics in horses with insulin dysregulation receiving phenylbutazone
Principal Advisor
Other advisors: Professor Paul Mills, Dr Allison Stewart
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Doctor Philosophy
The role of dopamine in the regulation of gastrointestinal health in horses with pituitary pars intermedia dysfunction.
Principal Advisor
Other advisors: Dr Justine Gibson, Dr Deirdre Mikkelsen, Dr Allison Stewart, Dr Viviana Gonzalez Astudillo
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Doctor Philosophy
Pathogenesis and prevention of laminitis
Associate Advisor
Other advisors: Professor Paul Mills
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Doctor Veterinary Clinical Sci
Maternal Antibody Decline and Natural Acquisition of Positive Titres to Flaviviruses in Foals
Associate Advisor
Other advisors: Professor Joanne Meers, Dr Allison Stewart
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Doctor Veterinary Clinical Sci
Maternal Antibody Decline and Natural Acquisition of Positive Titres to Flaviviruses in Foals
Associate Advisor
Other advisors: Professor Joanne Meers, Dr Allison Stewart
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Doctor Philosophy
In vitro modelling and treatment of laminitis using equine stem cells
Associate Advisor
Other advisors: Dr Albert Sole Guitart, Associate Professor Deanne Whitworth
Completed supervision
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2024
Doctor Philosophy
Investigating insulin and glucose dynamics in horses with insulin dysregulation receiving phenylbutazone
Principal Advisor
Other advisors: Professor Paul Mills, Dr Allison Stewart
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2023
Doctor Veterinary Clinical Sci
Epidemiological and genetic investigation of insulin dysregulation in ponies
Principal Advisor
Other advisors: Dr Allison Stewart
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2023
Doctor Philosophy
Studies of koala behavioural ecology and implications for koala conservation
Principal Advisor
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2023
Doctor Veterinary Clinical Sci
Alfaxalone anaesthesia in birds
Principal Advisor
Other advisors: Professor Bob Doneley, Professor Ben Ahern, Professor Joerg Henning
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2022
Doctor Philosophy
Effects of sensory environmental enrichment on the behaviour and heart rate variability of dogs in kennels
Associate Advisor
Other advisors: Dr Mary Broughton
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2020
Doctor Philosophy
Studies on the pathogenesis of insulin-induced laminitis in horses
Associate Advisor
Media
Enquiries
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