Associate Professor Francois-Rene Bertin
Associate Professor

Francois-Rene Bertin

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Background

Dr François-René Bertin (DVM, MS, PhD, dipl.ACVIM (LAIM)) is an equine internist with expertise in clinical endocrinology.

François-René completed a Doctorate of Veterinary Medicine (University of Nantes, France), an American College of Veterinary Internal Medicine (ACVIM) residency in equine internal medicine (Purdue University, USA) and a PhD in physiology (McGill University, Canada). He moved to the School of Veterinary Science at UQ in 2016.

François-René’s research interests lie in the pathophysiology of hyperinsulinaemia-associated laminitis and the disorders of the equine hypothalamo-pituitary adrenocortical axis. Some of his current projects examine the regulators of pancreatic b-cell activity and the mechanisms of pituitary gland senescence. François-René has received awards from the School of Veterinary Science and the Faculty of Science for his contribution to Research and HDR student supervision.

François-René teaches equine internal medicine into the veterinary science and veterinary technology programs and coordinates the Equine Clinical Studies course. He has received Teaching and Learning Faculty Awards.

Availability

Associate Professor Francois-Rene Bertin is:
Available for supervision
Media expert

Fields of research

Agricultural, Veterinary and Food Sciences Biomedical and Clinical Sciences Clinical sciences Endocrinology Veterinary sciences

Qualifications

  • Doctoral Diploma of Veterinary Medicine, Université de Nantes
  • Masters (Coursework) of Science, Purdue University
  • Doctor of Philosophy, McGill University
  • Fellow, American College of Veterinary Internal Medicine, American College of Veterinary Internal Medicine

Research interests

  • Equine endocrinology

  • Pancreatic b-cell activity

    Understanding the mechanisms associated with hyperinsulinaemia and the development of equine laminitis.

  • Hypothalamo-pituitary adrenocortical axis senescence

    Understanding the age-associated changes of the equine pituitary gland.

  • Clinical diagnostic testing

    Improving diagnostic testing of endocrine disorders in horses.

Search Professor Francois-Rene Bertin’s works on UQ eSpace

128 works between 2010 and 2025
All (128) Journal Article (60) Book Chapter (3) Conference Publication (62) Book (3)

41 - 60 of 128 works

2021

Conference Publication

Renal ultrasound and cystoscopy

Stewart, Allison J., Bertin, Francois-Rene and Clark, Brianna (2021). Renal ultrasound and cystoscopy. 3rd UQVETS Equine Practitioners Conference, Gatton, QLD, Australia, 2-3 February 2021.

Renal ultrasound and cystoscopy

2020

Journal Article

Oxytetracycline associated acute kidney injury in a neonatal foal

Fletcher, J. R., Bertin, F. R., Owen, H., Fraser, N. S., Rose, A. M. and Stewart, A. J. (2020). Oxytetracycline associated acute kidney injury in a neonatal foal. Equine Veterinary Education, 33 (10) eve.13372, e345-e351. doi: 10.1111/eve.13372

Oxytetracycline associated acute kidney injury in a neonatal foal

2020

Journal Article

Cumulative antibiogram and multidrug-resistant organisms in a regional equine referral hospital

Yuen, Ka Y., Gibson, Justine S., Hinrichsen, Sophia, Medina-Torres, Carlos E., Bertin, Francois-Rene and Stewart, Allison J. (2020). Cumulative antibiogram and multidrug-resistant organisms in a regional equine referral hospital. Journal of Veterinary Diagnostic Investigation, 33 (1), 149-155. doi: 10.1177/1040638720977478

Cumulative antibiogram and multidrug-resistant organisms in a regional equine referral hospital

2020

Journal Article

Essential oil spray reduces clinical signs of insect bite hypersensitivity in horses

Cox, A., Wood, K., Coleman, G., Stewart, A.J., Bertin, F‐R, Owen, H, Suen, W.W. and Medina‐Torres, C.E. (2020). Essential oil spray reduces clinical signs of insect bite hypersensitivity in horses. Australian Veterinary Journal, 98 (8) avj.12963, 411-416. doi: 10.1111/avj.12963

Essential oil spray reduces clinical signs of insect bite hypersensitivity in horses

2020

Journal Article

Lamellar energy metabolism and perfusion in the euglycaemic hyperinsulinaemic clamp model of equine laminitis

Stokes, Simon M., Bertin, Francois R., Stefanovski, Darko, Belknap, James K., Medina‐Torres, Carlos E., Pollitt, Christopher C. and Eps, Andrew W. (2020). Lamellar energy metabolism and perfusion in the euglycaemic hyperinsulinaemic clamp model of equine laminitis. Equine Veterinary Journal, 52 (4) evj.13224, 577-584. doi: 10.1111/evj.13224

Lamellar energy metabolism and perfusion in the euglycaemic hyperinsulinaemic clamp model of equine laminitis

2020

Journal Article

The effect of continuous digital hypothermia on lamellar energy metabolism and perfusion during laminitis development in two experimental models

Stokes, Simon M., Bertin, Francois-Rene, Stefanovski, Darko, Poulsen, Lea, Belknap, James K., Medina-Torres, Carlos E., Pollitt, Christopher C. and van Eps, Andrew W. (2020). The effect of continuous digital hypothermia on lamellar energy metabolism and perfusion during laminitis development in two experimental models. Equine Veterinary Journal, 52 (4) evj.13215, 585-592. doi: 10.1111/evj.13215

The effect of continuous digital hypothermia on lamellar energy metabolism and perfusion during laminitis development in two experimental models

2020

Journal Article

Effect of digital hypothermia on lamellar inflammatory signaling in the euglycemic hyperinsulinemic clamp laminitis model

Stokes, Simon M., Burns, Teresa A., Watts, Mauria R., Bertin, François‐René, Stefanovski, Darko, Medina‐Torres, Carlos E., Belknap, James K. and Eps, Andrew W. (2020). Effect of digital hypothermia on lamellar inflammatory signaling in the euglycemic hyperinsulinemic clamp laminitis model. Journal of Veterinary Internal Medicine, 34 (4) jvim.15835, 1606-1613. doi: 10.1111/jvim.15835

Effect of digital hypothermia on lamellar inflammatory signaling in the euglycemic hyperinsulinemic clamp laminitis model

2020

Journal Article

The effect of freeze-thaw cycles on determination of immunoreactive plasma adrenocorticotrophic hormone concentrations in horses

Hu, Ke, Stewart, Allison J., Yuen, Ka Y., Hinrichsen, Sophia, Dryburgh, Elizabeth L. and Bertin, François-René (2020). The effect of freeze-thaw cycles on determination of immunoreactive plasma adrenocorticotrophic hormone concentrations in horses. Journal of Veterinary Internal Medicine, 34 (3), 1350-1356. doi: 10.1111/jvim.15771

The effect of freeze-thaw cycles on determination of immunoreactive plasma adrenocorticotrophic hormone concentrations in horses

2020

Journal Article

Comparison of a continuous indwelling glucometer with a point-of-care device in healthy adult horses

Cunneen, Alexandra, Wood, Kelly A., Mathison, Kylie, Herndon, Aaron M. and Bertin, Francois R (2020). Comparison of a continuous indwelling glucometer with a point-of-care device in healthy adult horses. Veterinary Record, 187 (3), vetrec-2019. doi: 10.1136/vr.105607

Comparison of a continuous indwelling glucometer with a point-of-care device in healthy adult horses

2020

Journal Article

Blood glucose and insulin concentrations after alpha-2-agonists administration in horses with and without insulin dysregulation

Kritchevsky, Janice E., Muir, Genevieve S., Leschke, Dakota H. Z., Hodgson, Jack K., Hess, Emily K. and Bertin, Francois-Rene (2020). Blood glucose and insulin concentrations after alpha-2-agonists administration in horses with and without insulin dysregulation. Journal of Veterinary Internal Medicine, 34 (2) jvim.15747, 902-908. doi: 10.1111/jvim.15747

Blood glucose and insulin concentrations after alpha-2-agonists administration in horses with and without insulin dysregulation

2020

Conference Publication

Cardiac murmurs and arrhythmias

Medina-Torres, Carlos, Bertin, Francois-Rene and Stewart, Allison J. (2020). Cardiac murmurs and arrhythmias . 2nd UQVETS Equine Practitioners Conference, Gatton, QLD, Australia, 3-4 February 2020.

Cardiac murmurs and arrhythmias

2020

Conference Publication

Factors associated with critical illness related corticosteroid insufficiency (CIRCI) in adult horses

Stewart, Allison, Hackett, Elieen, Towns, Taylor and Bertin, Francois-Rene (2020). Factors associated with critical illness related corticosteroid insufficiency (CIRCI) in adult horses. 4th Global Equine Endocrinology Symposium, Gut Ising, Bavaria, Germany, 6-10 January 2020. Ingelheim, Germany: Boehringer Ingelheim.

Factors associated with critical illness related corticosteroid insufficiency (CIRCI) in adult horses

2020

Conference Publication

The effect of freeze-thaw cycles on the determination of immunoreactive adrenocorticotrophic hormone concentrations in horses

Hu, Ke, Stewart, Allison, Yuen, Ka, Hinrichsen, Sophia, Dryburgh, Elizabeth and Bertin, Francois-Rene (2020). The effect of freeze-thaw cycles on the determination of immunoreactive adrenocorticotrophic hormone concentrations in horses. 4th Global Equine Endocrinology Symposium, Gut Ising, Bavaria, Germany, 7-9 January 2020. Ingelheim, Germany: Boehringer Ingelheim.

The effect of freeze-thaw cycles on the determination of immunoreactive adrenocorticotrophic hormone concentrations in horses

2020

Journal Article

Diagnosis and treatment of confirmed and suspected primary hyperparathyroidism in equids: 17 cases (1999–2016)

Gorenberg, E. B., Johnson, A. L., Magdesian, K. G., Bertin, F. R., Costa, L. R.R., Theelen, M. J.P., Durward-Akhurst, S. A., Cruz Villagrán, C., Carslake, H., Frank, N. and Tomlinson, J. E. (2020). Diagnosis and treatment of confirmed and suspected primary hyperparathyroidism in equids: 17 cases (1999–2016). Equine Veterinary Journal, 52 (1) evj.13120, 83-90. doi: 10.1111/evj.13120

Diagnosis and treatment of confirmed and suspected primary hyperparathyroidism in equids: 17 cases (1999–2016)

2020

Conference Publication

Comparison of autumnal adrenocorticotropic hormone (ACTH) concentrations between apparently healthy horses and ponies

Bamford, Nicholas, Bertin, Francois-Rene, El-Haige, Charlie, Stewart, Allison and Bailey, Simon (2020). Comparison of autumnal adrenocorticotropic hormone (ACTH) concentrations between apparently healthy horses and ponies. 4th Global Equine Endocrinology Symposium, Gut Ising, Bavaria, Germany, 6-10 January 2020. Ingelhem, Germany: Boehringer Ingelheim.

Comparison of autumnal adrenocorticotropic hormone (ACTH) concentrations between apparently healthy horses and ponies

2020

Book Chapter

Neuroaxonal dystrophy/equine degenerative myeloencephalopathy

Bertin, François-René (2020). Neuroaxonal dystrophy/equine degenerative myeloencephalopathy. Blackwell's five-minute veterinary consult: Equine. (pp. 509-510) edited by Jean-Pierre Lavoie. Hoboken, NJ United States: John Wiley and Sons.

Neuroaxonal dystrophy/equine degenerative myeloencephalopathy

2020

Conference Publication

Effect of sample handling on adrenocorticotropic hormone (ACTH) concentrations following thyrotropin-releasing hormone (TRH) stimulation in horses

Stewart, Allison, Yuen, K., Hinrichsen, Sophia, Dryburgh, Elizabeth and Bertin, Francois-Rene (2020). Effect of sample handling on adrenocorticotropic hormone (ACTH) concentrations following thyrotropin-releasing hormone (TRH) stimulation in horses. 4th Global Equine Endocrinology Symposium, Gut Ising, Bavaria, Germany, 6-10 January 2020. Ingelheim, Germany: Boehringer Ingelheim.

Effect of sample handling on adrenocorticotropic hormone (ACTH) concentrations following thyrotropin-releasing hormone (TRH) stimulation in horses

2019

Journal Article

Immunoreactive insulin stability in horses at risk of insulin dysregulation

Leschke, Dakota H., Muir, Genevieve S., Hodgson, Jack K., Coyle, Mitchell, Horn, Remona and Bertin, François‐René (2019). Immunoreactive insulin stability in horses at risk of insulin dysregulation. Journal of Veterinary Internal Medicine, 33 (6) jvim.15629, 2746-2751. doi: 10.1111/jvim.15629

Immunoreactive insulin stability in horses at risk of insulin dysregulation

2019

Journal Article

Evaluation of combined testing to simultaneously diagnose pituitary pars intermedia dysfunction and insulin dysregulation in horses

Horn, Remona and Bertin, François‐René (2019). Evaluation of combined testing to simultaneously diagnose pituitary pars intermedia dysfunction and insulin dysregulation in horses. Journal of Veterinary Internal Medicine, 33 (5) jvim.15617, 2249-2256. doi: 10.1111/jvim.15617

Evaluation of combined testing to simultaneously diagnose pituitary pars intermedia dysfunction and insulin dysregulation in horses

2019

Journal Article

Cortisol and adrenocorticotropic hormone concentrations in horses with systemic inflammatory response syndrome

Stewart, Allison J., Hackett, Eileen, Bertin, Francois‐Rene and Towns, Taylor J. (2019). Cortisol and adrenocorticotropic hormone concentrations in horses with systemic inflammatory response syndrome. Journal of Veterinary Internal Medicine, 33 (5) jvim.15620, 2257-2266. doi: 10.1111/jvim.15620

Cortisol and adrenocorticotropic hormone concentrations in horses with systemic inflammatory response syndrome

Current funding

  • 2024 - 2025
    Role of plasma extracellular vesicles in equine metabolic syndrome (EMS) condition
    Research Donation Generic
    Open grant
  • 2018 - 2026
    Hendra virus antibody titres in foals derived from maternal antibodies and in response to vaccination
    John & Mary Kibble Trust
    Open grant

Past funding

  • 2023 - 2024
    The role of dopamine in intestinal inflammation and oxidation in horses with pituitary pars intermedia dysfunction
    Research Donation Generic
    Open grant
  • 2022 - 2024
    Determination of proteomic and lipidomic profiles of horses with Equine Metabolic Syndrome and hyperinsulinemia-associated laminitis
    Boehringer Ingelheim Vetmedica GmbH
    Open grant
  • 2022 - 2023
    Controlling Insulin Dysregulation with Sirolimus (Grayson-Jockey Club Research Foundation administered by UPenn).
    University of Pennsylvania
    Open grant
  • 2021 - 2022
    Epidemiological and genetic evaluation of insulin dysregulation in ponies
    Resident Research Grants
    Open grant
  • 2020 - 2021
    Part 2 - Efficacy clinical trial of new oral pergolide in horses
    Luoda Pharma Pty Ltd
    Open grant
  • 2020 - 2023
    Dopamine as a new diagnostic tool for horses with pituitary pars intermedia dysfunction and its effect on the equine intestinal microbiota
    Australian Companion Animal Health Foundation
    Open grant
  • 2019 - 2023
    Evaluation of a Genetic test for Equine Metabolic Syndrome in Ponies
    Research Donation Generic
    Open grant
  • 2019 - 2023
    Investigating insulin and glucose dynamics in horses with Equine Metabolic Syndrome receiving Phenylbutazone
    Morris Animal Foundation
    Open grant
  • 2019 - 2022
    Endocrine profiles and reproduction performance in mares
    Research Donation Generic
    Open grant
  • 2019 - 2020
    Automated immunohistochemical analysis module for the expansion of research and clinical diagnostic capabilities at UQ
    UQ Major Equipment and Infrastructure
    Open grant
  • 2019 - 2020
    Improvement of insulin stability in horses at risk of Equine Metabolic Syndrome
    John & Mary Kibble Trust
    Open grant
  • 2018
    Efficacy clinical trial of an herbal formulation to treat equine insect bite hypersensitivity
    Red Healer
    Open grant
  • 2018
    Assessment of value of a combined thyrotropin-releasing hormone stimulation test and 2-step insulin response test to diagnose Equine Pituitary Pars Intermedia Dysfunction and Equine Metabolic Syndrome
    UQ Early Career Researcher
    Open grant
  • 2017 - 2021
    Stability of equine adrenocorticotropic hormone (ACTH) under conditions encountered by Australian veterinarians
    Boehringer Ingelheim Pty Ltd
    Open grant
  • 2017 - 2018
    Establishment of seasonal reference intervals for adrenocorticotropic hormone (ACTH) concentrations for horses in Southern Queensland
    Research Donation Generic
    Open grant

Availability

Associate Professor Francois-Rene Bertin is:
Available for supervision

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Available projects

  • Insulin dysregulation

    Insulin dysregulation is the hallmark of equine metabolic syndrome and has received attention because of its direct association with laminitis. In the absence of an adequate treatment for laminitis, our research focuses on the mechanisms leading to laminitis as well as on the early detection of individuals at risk of developing laminitis.

  • Hypothalamus-pituitary-adrenal dysfunctions

    The hypothalamo-pituitary-adrenal axis is a major regulator of homeostasis. With sickness or with age, this axis can be dysregulated leading to critical illness-related corticosteroid insufficiency or to pituitary pars intermedia dysfunction (PPID) respectively. The latter is a common condition of older horses that can result in laminitis and our research focuses on the detection and management of horses developping PPID.

Supervision history

Current supervision

Completed supervision

Enquiries

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