Overview
Background
Dr François-René Bertin (DVM, MS, PhD, dipl.ACVIM (LAIM)) is an equine internist with expertise in clinical endocrinology.
François-René completed a Doctorate of Veterinary Medicine (University of Nantes, France), an American College of Veterinary Internal Medicine (ACVIM) residency in equine internal medicine (Purdue University, USA) and a PhD in physiology (McGill University, Canada). He moved to the School of Veterinary Science at UQ in 2016.
François-René’s research interests lie in the pathophysiology of hyperinsulinaemia-associated laminitis and the disorders of the equine hypothalamo-pituitary adrenocortical axis. Some of his current projects examine the regulators of pancreatic b-cell activity and the mechanisms of pituitary gland senescence. François-René has received awards from the School of Veterinary Science and the Faculty of Science for his contribution to Research and HDR student supervision.
François-René teaches equine internal medicine into the veterinary science and veterinary technology programs and coordinates the Equine Clinical Studies course. He has received Teaching and Learning Faculty Awards.
Availability
- Associate Professor Francois-Rene Bertin is:
- Available for supervision
- Media expert
Fields of research
Qualifications
- Doctoral Diploma of Veterinary Medicine, Université de Nantes
- Masters (Coursework) of Science, Purdue University
- Doctor of Philosophy, McGill University
- Fellow, American College of Veterinary Internal Medicine, American College of Veterinary Internal Medicine
Research interests
-
Equine endocrinology
-
Pancreatic b-cell activity
Understanding the mechanisms associated with hyperinsulinaemia and the development of equine laminitis.
-
Hypothalamo-pituitary adrenocortical axis senescence
Understanding the age-associated changes of the equine pituitary gland.
-
Clinical diagnostic testing
Improving diagnostic testing of endocrine disorders in horses.
Works
Search Professor Francois-Rene Bertin’s works on UQ eSpace
2016
Journal Article
Cerebrospinal nematodiasis in 20 camelids
Bertin, F. R. and Taylor, S. D. (2016). Cerebrospinal nematodiasis in 20 camelids. Journal of Veterinary Internal Medicine, 30 (4), 1390-1395. doi: 10.1111/jvim.13958
2016
Journal Article
What’s new in old horses? Post-mortem diagnoses in mature and aged equids
Miller, M. A., Moore, G. E., Bertin, F. R. and Kritchevsky, J. E. (2016). What’s new in old horses? Post-mortem diagnoses in mature and aged equids. Veterinary Pathology, 53 (2), 390-398. doi: 10.1177/0300985815608674
2016
Journal Article
Prostaglandin E synthase is upregulated by Gas6 during cancer-induced venous thrombosis
Aghourian, Meghedi N., Lemarie, Catherine A., Bertin, Francois-Rene and Blostein, Mark D. (2016). Prostaglandin E synthase is upregulated by Gas6 during cancer-induced venous thrombosis. Blood, 127 (6), 769-777. doi: 10.1182/blood-2015-02-628867
2016
Conference Publication
Natural Killer Cells Induce the Formation of Neutrophil Extracellular Traps (NETs) in Venous Thrombosis
Bertin, F. R., S. Laurance, C.A. Lemarie and M.D. Blostein (2016). Natural Killer Cells Induce the Formation of Neutrophil Extracellular Traps (NETs) in Venous Thrombosis. American Society of Hematology 58th Annual Meeting, San Diego, 3-6 December 2016.
2015
Journal Article
Growth arrest-specific 6 regulates thrombin-induced expression of vascular cell adhesion molecule-1 through forkhead box O1 in endothelial cells
Bertin, F. R., Lemarie, C. A., Robins, R. S. and Blostein, M. D. (2015). Growth arrest-specific 6 regulates thrombin-induced expression of vascular cell adhesion molecule-1 through forkhead box O1 in endothelial cells. Journal of Thrombosis and Haemostasis, 13 (12), 2260-2272. doi: 10.1111/jth.13156
2015
Journal Article
Clinical findings and survival in 56 sick neonatal new world camelids
Bertin, F. R., Squires, J. M., Kritchevsky, J. E. and Taylor, S. D. (2015). Clinical findings and survival in 56 sick neonatal new world camelids. Journal of Veterinary Internal Medicine, 29 (1), 368-374. doi: 10.1111/jvim.12478
2015
Conference Publication
Extracellular RNA induces venous thrombosis through TLR3
Lemarie, C. A., Sidhu, M., Angela, L. N., Laurance, S., Bertin, F-R and Blostein, M. D. (2015). Extracellular RNA induces venous thrombosis through TLR3. XXV Congress of the International Society on Thrombosis and Haemostasis, Toronto, Canada, 20-25 June 2015. Chichester, West Sussex, United Kingdom: Wiley-Blackwell Publishing. doi: 10.1111/jth.12993
2014
Conference Publication
Gas6 Promotes Pro-Inflammatory (Ly6C(hi)) Monocyte Recruitment in Venous Thrombosis
Laurance, Sandrine, Bertin, Francois-Rene, Ebrahimian, Talin, Lehoux, Stephanie, Lemarie, Catherine A. and Blostein, Mark D. (2014). Gas6 Promotes Pro-Inflammatory (Ly6C(hi)) Monocyte Recruitment in Venous Thrombosis. 56th Annual Meeting of the American-Society-of-Hematology, San Francisco Ca, Dec 06-09, 2014. WASHINGTON: AMER SOC HEMATOLOGY. doi: 10.1182/blood.V124.21.1533.1533
2014
Journal Article
Evaluation of a technique for percutaneous endoscopic gastrotomy tube placement in horses
Toth, Balazs, Bertin, Francois R., Miller, Margaret A., Charney, Virginia A. and Kritchevsky, Janice E. (2014). Evaluation of a technique for percutaneous endoscopic gastrotomy tube placement in horses. American Journal of Veterinary Research, 75 (4), 354-360. doi: 10.2460/ajvr.75.4.354
2014
Journal Article
Pathology in practice
Charney, Virginia A., Bertin, Francois R., Sojka-Kritchesky, Janice E. and Miller, Margaret A. (2014). Pathology in practice. Journal of the American Veterinary Medicine Association, 244 (5), 541-543. doi: 10.2460/javma.244.5.541
2014
Conference Publication
Gas6 promotes pro-inflammatory (Ly6Chi) monocyte recruitment in venous thrombosis
Laurance, S., Bertin, F. R., Lemarié, C. A. and Blostein, M. D. (2014). Gas6 promotes pro-inflammatory (Ly6Chi) monocyte recruitment in venous thrombosis. 56th Annual Meeting of the American Society of Hematology, San Francisco, CA, United States, 6-9 December 2014. Washington, DC, United States: American Society of Hematology.
2014
Conference Publication
Prostaglandin E synthase is upregulated by Gas6 during cancer-induced venous thromboembolism
Aghourian, Meghedi N., Lemarie, Catherine A., Bertin, Francois-Rene and Blostein, Mark D. (2014). Prostaglandin E synthase is upregulated by Gas6 during cancer-induced venous thromboembolism. 56th Annual Meeting of the American Society of Hematology, San Francisco, CA, United States, 6-9 December 2014. Washington, DC, United States: American Society of Hematology.
2014
Book Chapter
Les medicaments anti-tumoraux
Bertin, F. R., Tamzali, Y. and Lussot-Kervern, I. (2014). Les medicaments anti-tumoraux. Guide de Thérapeutique équine. (pp. 138-148) edited by J. Bardies. Rueil-Malmaison, France: Point Vétérinaire.
2014
Conference Publication
Extracellular RNA induces Venous Thrombosis Through TLR3
Lemarie, Catherine A., Le, Angela N., Laurance, Sandrine , Bertin, François-René and Blostein, Mark D. (2014). Extracellular RNA induces Venous Thrombosis Through TLR3. Annual Conference on Arteriosclerosis, Thrombosis, and Vascular Biology, Toronto, Canada, 1-3 May 2014. PHILADELPHIA: LIPPINCOTT WILLIAMS & WILKINS.
2014
Conference Publication
Gas6 Is Required for Thrombin-Induced Expression of VCAM-1 through Foxo-1 in Endothelial Cells
Bertin, Francois-Rene, Robins, Richard, Lemarie, Catherine A. and Blostein, Mark D. (2014). Gas6 Is Required for Thrombin-Induced Expression of VCAM-1 through Foxo-1 in Endothelial Cells. 56th Annual Meeting of the American-Society-of-Hematology, San Francisco Ca, Dec 06-09, 2014. Washington, DC, United States: American Society of Hematology.
2013
Journal Article
The short-term effect of ovariectomy on measures of insulin sensitivity and response to dexamethasone in mares
Bertin, François, Pader, Karine, Lescun, Timothy B. and Sojka-Kritchevsky, Janice E. (2013). The short-term effect of ovariectomy on measures of insulin sensitivity and response to dexamethasone in mares. American Journal of Veterinary Research, 74 (12), 1506-1513. doi: 10.2460/ajvr.74.12.1506
2013
Journal Article
Clinical and clinicopathological factors associated with survival in 44 horses with equine neorickettsiosis (potomac horse fever)
Bertin, F. R., Reising, A., Slovis, N. M., Constable, P. D. and Taylor, S. D. (2013). Clinical and clinicopathological factors associated with survival in 44 horses with equine neorickettsiosis (potomac horse fever). Journal of Veterinary Internal Medicine, 27 (6), 1528-1534. doi: 10.1111/jvim.12209
2013
Journal Article
Arsenic toxicosis in cattle: meta-analysis of 156 cases
Bertin, F. R., Baseler, L. J., Wilson, C. R., Kritchevsky, J. E. and Taylor, S. D. (2013). Arsenic toxicosis in cattle: meta-analysis of 156 cases. Journal of Veterinary Internal Medicine, 27 (4), 977-981. doi: 10.1111/jvim.12124
2013
Conference Publication
Percutaneous endoscopic gastrotomy (PEG) tube placement in horses
Toth, B., Bertin, F. R., Miller, M. A., Charney, V. and Kritchevsky, J. E. (2013). Percutaneous endoscopic gastrotomy (PEG) tube placement in horses. Forum of the American College of Veterinary Internal Medicine, Seattle, June 2013. HOBOKEN: WILEY-BLACKWELL.
2013
Conference Publication
Vascular Tlr3 activation is involved in neutrophil recruitment during venous thrombosis
Lemarie, C., Laurance, S., Le, A. N., Bertin, F. and Blostein, M. D. (2013). Vascular Tlr3 activation is involved in neutrophil recruitment during venous thrombosis. Canadian Cardiovascular Congress 2013: 66th Annual Meeting of the Canadian Cardiovascular Society, Montréal, Canada, 17–20 October 2013. New York, United States: Elsevier. doi: 10.1016/j.cjca.2013.07.250
Funding
Current funding
Supervision
Availability
- Associate Professor Francois-Rene Bertin is:
- Available for supervision
Before you email them, read our advice on how to contact a supervisor.
Available projects
-
Insulin dysregulation
Insulin dysregulation is the hallmark of equine metabolic syndrome and has received attention because of its direct association with laminitis. In the absence of an adequate treatment for laminitis, our research focuses on the mechanisms leading to laminitis as well as on the early detection of individuals at risk of developing laminitis.
-
Hypothalamus-pituitary-adrenal dysfunctions
The hypothalamo-pituitary-adrenal axis is a major regulator of homeostasis. With sickness or with age, this axis can be dysregulated leading to critical illness-related corticosteroid insufficiency or to pituitary pars intermedia dysfunction (PPID) respectively. The latter is a common condition of older horses that can result in laminitis and our research focuses on the detection and management of horses developping PPID.
Supervision history
Current supervision
-
Doctor Philosophy
The role of dopamine in the regulation of gastrointestinal health in horses with pituitary pars intermedia dysfunction.
Principal Advisor
Other advisors: Dr Justine Gibson, Dr Deirdre Mikkelsen, Dr Viviana Gonzalez Astudillo, Dr Allison Stewart
-
Doctor Veterinary Clinical Sci
Maternal Antibody Decline and Natural Acquisition of Positive Titres to Flaviviruses in Foals
Associate Advisor
Other advisors: Professor Joanne Meers, Dr Allison Stewart
-
Doctor Philosophy
In vitro modelling and treatment of laminitis using equine stem cells
Associate Advisor
Other advisors: Dr Albert Sole Guitart, Associate Professor Deanne Whitworth
Completed supervision
-
2024
Doctor Philosophy
Investigating insulin and glucose dynamics in horses with insulin dysregulation receiving phenylbutazone
Principal Advisor
Other advisors: Professor Paul Mills, Dr Allison Stewart
-
2023
Doctor Veterinary Clinical Sci
Epidemiological and genetic investigation of insulin dysregulation in ponies
Principal Advisor
Other advisors: Dr Allison Stewart
-
2023
Doctor Philosophy
Studies of koala behavioural ecology and implications for koala conservation
Principal Advisor
-
2023
Doctor Veterinary Clinical Sci
Alfaxalone anaesthesia in birds
Principal Advisor
Other advisors: Professor Bob Doneley, Professor Ben Ahern, Professor Joerg Henning
-
2022
Doctor Philosophy
Effects of sensory environmental enrichment on the behaviour and heart rate variability of dogs in kennels
Associate Advisor
Other advisors: Dr Mary Broughton
-
2020
Doctor Philosophy
Studies on the pathogenesis of insulin-induced laminitis in horses
Associate Advisor
Media
Enquiries
Contact Associate Professor Francois-Rene Bertin directly for media enquiries about their areas of expertise.
Need help?
For help with finding experts, story ideas and media enquiries, contact our Media team: