Dr

Christian Nefzger

Email: 
Phone: 
+61 7 334 62053

Background

Kindly visit my laboratory's webpage for more information

Availability

Dr Christian Nefzger is:
Available for supervision

Qualifications

  • Doctor of Philosophy, Monash University

Research impacts

Kindly visit my laboratory's webpage for more information

Search Professor Christian Nefzger’s works on UQ eSpace

53 works between 2011 and 2024
All (53) Journal Article (49) Book Chapter (3) Conference Publication (1)

41 - 53 of 53 works

2016

Journal Article

An improved reprogrammable mouse model harbouring the reverse tetracycline-controlled transcriptional transactivator 3

Alaei, S., Knaupp, A. S., Lim, S. M., Chen, J., Holmes, M. L., Anko, M. L., Nefzger, C. M. and Polo, J. M. (2016). An improved reprogrammable mouse model harbouring the reverse tetracycline-controlled transcriptional transactivator 3. Stem Cell Research, 17 (1), 49-53. doi: 10.1016/j.scr.2016.05.008

An improved reprogrammable mouse model harbouring the reverse tetracycline-controlled transcriptional transactivator 3

2016

Journal Article

A versatile strategy for isolating a highly enriched population of intestinal stem cells

Nefzger, Christian M., Jarde, Thierry, Rossello, Fernando J., Horvay, Katja, Knaupp, Anja S., Powell, David R., Chen, Joseph, Abud, Helen E. and Polo, Jose M. (2016). A versatile strategy for isolating a highly enriched population of intestinal stem cells. Stem Cell Reports, 6 (3), 321-329. doi: 10.1016/j.stemcr.2016.01.014

A versatile strategy for isolating a highly enriched population of intestinal stem cells

2016

Journal Article

A predictive computational framework for direct reprogramming between human cell types

Rackham, Owen J. L., Firas, Jaber, Fang, Hai, Oates, Matt E., Holmes, Melissa L., Knaupp, Anja S., Suzuki, Harukazu, Nefzger, Christian M., Daub, Carsten O., Shin, Jay W., Petretto, Enrico, Forrest, Alistair R. R., Hayashizaki, Yoshihide, Polo, Jose M. and Gough, Julian (2016). A predictive computational framework for direct reprogramming between human cell types. Nature Genetics, 48 (3), 331-335. doi: 10.1038/ng.3487

A predictive computational framework for direct reprogramming between human cell types

2015

Journal Article

Snai1 regulates cell lineage allocation and stem cell maintenance in the mouse intestinal epithelium

Horvay, Katja, Jarde, Thierry, Casagranda, Franca, Perreau, Victoria M., Haigh, Katharina, Nefzger, Christian M., Akhtar, Reyhan, Gridley, Thomas, Berx, Geert, Haigh, Jody J., Barker, Nick, Polo, Jose M., Hime, Gary R. and Abud, Helen E. (2015). Snai1 regulates cell lineage allocation and stem cell maintenance in the mouse intestinal epithelium. The EMBO Journal, 34 (10), 1319-1335. doi: 10.15252/embj.201490881

Snai1 regulates cell lineage allocation and stem cell maintenance in the mouse intestinal epithelium

2015

Book Chapter

Isolation of reprogramming intermediates during generation of induced pluripotent stem cells from mouse embryonic fibroblasts

Nefzger, Christian M., Alaei, Sara and Polo, Jose M. (2015). Isolation of reprogramming intermediates during generation of induced pluripotent stem cells from mouse embryonic fibroblasts. Cell reprogramming: methods and protocols. (pp. 205-218) New York, NY USA: Springer. doi: 10.1007/978-1-4939-2848-4_17

Isolation of reprogramming intermediates during generation of induced pluripotent stem cells from mouse embryonic fibroblasts

2014

Journal Article

Cell surface marker mediated purification of iPS cell intermediates from a reprogrammable mouse model

Nefzger, Christian M., Alaei, Sara, Knaupp, Anja S., Holmes, Melissa L. and Polo, Jose M. (2014). Cell surface marker mediated purification of iPS cell intermediates from a reprogrammable mouse model. Jove-Journal of Visualized Experiments (91) e51728. doi: 10.3791/51728

Cell surface marker mediated purification of iPS cell intermediates from a reprogrammable mouse model

2014

Journal Article

GM-CSF and MEF-conditioned media support feeder-free reprogramming of mouse granulocytes to iPS cells

Firas, Jaber, Liu, Xiaodong, Nefzger, Christian M. and Polo, Jose M. (2014). GM-CSF and MEF-conditioned media support feeder-free reprogramming of mouse granulocytes to iPS cells. Differentiation, 87 (5), 193-199. doi: 10.1016/j.diff.2014.05.003

GM-CSF and MEF-conditioned media support feeder-free reprogramming of mouse granulocytes to iPS cells

2013

Journal Article

Mitochondrial DNA haplotypes define gene expression patterns in pluripotent and differentiating embryonic stem cells

Kelly, Richard D. W., Rodda, Andrew E., Dickinson, Adam, Mahmud, Arsalan, Nefzger, Christian M., Lee, William, Forsythe, John S., Polo, Jose M., Trounce, Ian A., McKenzie, Matthew, Nisbet, David R. and St John, Justin C. (2013). Mitochondrial DNA haplotypes define gene expression patterns in pluripotent and differentiating embryonic stem cells. Stem Cells, 31 (4), 703-716. doi: 10.1002/stem.1313

Mitochondrial DNA haplotypes define gene expression patterns in pluripotent and differentiating embryonic stem cells

2013

Journal Article

Probing transcription factor diffusion dynamics in the living mammalian embryo with photoactivatable fluorescence correlation spectroscopy

Kaur, Gurpreet, Costa, Mauro W., Nefzger, Christian M., Silva, Juan, Fierro-Gonzalez, Juan Carlos, Polo, Jose M., Bell, Toby D. M. and Plachta, Nicolas (2013). Probing transcription factor diffusion dynamics in the living mammalian embryo with photoactivatable fluorescence correlation spectroscopy. Nature Communications, 4 (1) 1637. doi: 10.1038/ncomms2657

Probing transcription factor diffusion dynamics in the living mammalian embryo with photoactivatable fluorescence correlation spectroscopy

2012

Journal Article

A molecular roadmap of reprogramming somatic cells into iPS cells

Polo, Jose M., Anderssen, Endre, Walsh, Ryan M., Schwarz, Benjamin A., Nefzger, Christian M., Lim, Sue Mei, Borkent, Marti, Apostolou, Effie, Alaei, Sara, Cloutier, Jennifer, Bar-Nur, Ori, Cheloufi, Sihem, Stadtfeld, Matthias, Figueroa, Maria Eugenia, Robinton, Daisy, Natesan, Sridaran, Melnick, Ari, Zhu, Jinfang, Ramaswamy, Sridhar and Hochedlinger, Konrad (2012). A molecular roadmap of reprogramming somatic cells into iPS cells. Cell, 151 (7), 1617-1632. doi: 10.1016/j.cell.2012.11.039

A molecular roadmap of reprogramming somatic cells into iPS cells

2012

Journal Article

Lmx1a allows context-specific isolation of progenitors of GABAergic or Dopaminergic neurons during neural differentiation of embryonic stem cells

Nefzger, Christian M., Su, Colin T., Fabb, Stewart A., Hartley, Brigham J., Beh, Siew J., Zeng, Wendy R., Haynes, John M. and Pouton, Colin W. (2012). Lmx1a allows context-specific isolation of progenitors of GABAergic or Dopaminergic neurons during neural differentiation of embryonic stem cells. Stem Cells, 30 (7), 1349-1361. doi: 10.1002/stem.1105

Lmx1a allows context-specific isolation of progenitors of GABAergic or Dopaminergic neurons during neural differentiation of embryonic stem cells

2011

Journal Article

Midbrain and forebrain patterning delivers immunocytochemically and functionally similar populations of neuropeptide Y containing GABAergic neurons

Khaira, S. K., Nefzger, C. M., Beh, S. J., Pouton, C. W. and Haynes, J. M. (2011). Midbrain and forebrain patterning delivers immunocytochemically and functionally similar populations of neuropeptide Y containing GABAergic neurons. Neurochemistry International, 59 (3), 413-420. doi: 10.1016/j.neuint.2011.02.016

Midbrain and forebrain patterning delivers immunocytochemically and functionally similar populations of neuropeptide Y containing GABAergic neurons

2011

Journal Article

Directed expression of Gata2, Mash1, and Foxa2 synergize to induce the serotonergic neuron phenotype during in vitro differentiation of embryonic stem cells

Nefzger, Christian M., Haynes, John M. and Pouton, Colin W. (2011). Directed expression of Gata2, Mash1, and Foxa2 synergize to induce the serotonergic neuron phenotype during in vitro differentiation of embryonic stem cells. Stem Cells, 29 (6), 928-939. doi: 10.1002/stem.640

Directed expression of Gata2, Mash1, and Foxa2 synergize to induce the serotonergic neuron phenotype during in vitro differentiation of embryonic stem cells

Current funding

  • 2024 - 2025
    Leveraging Spatial Transcriptomics to Study Liver ageing (Taif University administered Hevolution grant)
    Taif University
    Open grant

Past funding

  • 2022 - 2023
    Expanding The Scope Of Multimodal Single Cell Sequencing To Establishing A Gene Screening Platform
    Innovation Connections
    Open grant
  • 2022 - 2024
    Reinforcing the cell identity network to improve the function of aged cells
    NHMRC IDEAS Grants
    Open grant
  • 2021
    Gene screening platform
    Innovation Connections
    Open grant
  • 2020 - 2024
    Investigation of genetic drivers of Attention-deficit/hyperactivity disorder in the Saudi population (Taif University internal funding scheme led by Taif University)
    Taif University
    Open grant
  • 2020 - 2024
    Investigation of genetic drivers of Autism in the Saudi population (Taif University internal scheme grant led by Taif University)
    Taif University
    Open grant
  • 2020 - 2022
    Generation of human intestinal stem cells by direct reprogramming
    NHMRC Project Grant
    Open grant

Availability

Dr Christian Nefzger is:
Available for supervision

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Supervision history

Current supervision

  • Doctor Philosophy

    Understanding and controlling the age-stage of somatic cells

    Principal Advisor

    Other advisors: Professor Di Yu

  • Doctor Philosophy

    Leveraging integrative multiomic data to enable controlled cell state transition

    Principal Advisor

    Other advisors: Professor Matt Sweet, Dr Marina Naval Sanchez

  • Doctor Philosophy

    Leveraging integrative multiomic data to enable controlled cell state transition

    Principal Advisor

    Other advisors: Professor Matt Sweet, Dr Marina Naval Sanchez

  • Doctor Philosophy

    Network reinforcement to improve the function of aged cells

    Principal Advisor

    Other advisors: Dr Marina Naval Sanchez

  • Doctor Philosophy

    Development of a multimodal single-cell assay reveals somatic NFI transcription factors as dose-dependent pluripotency mediators

    Principal Advisor

    Other advisors: Professor Matt Sweet, Dr Marina Naval Sanchez

  • Doctor Philosophy

    Deciphering the age-altered transcription factor network and its control over regenerative potential

    Principal Advisor

    Other advisors: Dr Quan Nguyen, Dr Marina Naval Sanchez

  • Doctor Philosophy

    Developing small molecule inhibitors to control transcription factor redistribution

    Associate Advisor

    Other advisors: Dr Evelyne Deplazes

Completed supervision

Enquiries

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