Skip to menu Skip to content Skip to footer
Dr Marina Naval Sanchez
Dr

Marina Naval Sanchez

Email: 

Overview

Background

Dr. Marina Naval-Sanchez is a NHMRC Research Fellow at the Institute for Molecular Bioscience at The University of Queensland (Australia). She pursued postdoctoral studies in 2019-2024 in the Institute for Molecular Bioscience, The University of Queensland (Australia) and as an Office Chief Executive (OCE) Fellow in 2015-2019 at the Commonwealth Scientific and Industrial Research Organisation (CSIRO) (Australia). She received her PhD in Molecular Biosciences in 2014 from KULeuven (Belgium). She received her MSc in Applied Bioinformatics in 2009 from Cranfield University (UK) and MSc in Agriculture Engineering in 2008 from the Universitat de Lleida (Spain).

Marina’s research program applies state-of-the-art bioinformatic, machine learning, and genetic and genomic tools to unearth the master regulators and enhancer grammar governing development and ageing across species (mouse and human) and to decipher the genomic (regulatory) impact of evolution, domestication and human selection in farm species (sheep, cattle, salmon). Her research outcomes have been published in high-impact journals such as Cell Metabolism, Nature Communications, Genome Biology, Nucleic Acids Research, Genome Research and Molecular Biology and Evolution.

Her research efforts have been supported by domestic and international fellowships and grants, including the Australian National Health and Medical Research Council (NHMRC, EL1 2024 Recipient), Advance Queensland, UQ Innovation Connections, CSIRO Scientific Investment Projects, CSIRO OCE Fellowships, and Flanders Wetesnchappelijk Onderzoek (FWO) PhD Fellowship.

Availability

Dr Marina Naval Sanchez is:
Available for supervision

Qualifications

  • Doctor of Philosophy, Catholic University of Leuven

Works

Search Professor Marina Naval Sanchez’s works on UQ eSpace

35 works between 2008 and 2024

1 - 20 of 35 works

2024

Journal Article

Endothelial c-Src Mediates Neovascular Tuft Formation in Oxygen-Induced Retinopathy

Frampton, Emmanuelle, Som, Priyanka, Hill, Brittany, Yu, Alexander, Naval-Sanchez, Marina, Nefzger, Chistian M., Noordstra, Ivar, Gordon, Emma and Schimmel, Lilian (2024). Endothelial c-Src Mediates Neovascular Tuft Formation in Oxygen-Induced Retinopathy. The American Journal of Pathology, 194 (12), 2239-2251. doi: 10.1016/j.ajpath.2024.09.003

Endothelial c-Src Mediates Neovascular Tuft Formation in Oxygen-Induced Retinopathy

2024

Journal Article

The activity of early-life gene regulatory elements is hijacked in aging through pervasive AP-1-linked chromatin opening

Patrick, Ralph, Naval-Sanchez, Marina, Deshpande, Nikita, Huang, Yifei, Zhang, Jingyu, Chen, Xiaoli, Yang, Ying, Tiwari, Kanupriya, Esmaeili, Mohammadhossein, Tran, Minh, Mohamed, Amin R., Wang, Binxu, Xia, Di, Ma, Jun, Bayliss, Jacqueline, Wong, Kahlia, Hun, Michael L., Sun, Xuan, Cao, Benjamin, Cottle, Denny L., Catterall, Tara, Barzilai-Tutsch, Hila, Troskie, Robin-Lee, Chen, Zhian, Wise, Andrea F., Saini, Sheetal, Soe, Ye Mon, Kumari, Snehlata, Sweet, Matthew J. ... Nefzger, Christian M. (2024). The activity of early-life gene regulatory elements is hijacked in aging through pervasive AP-1-linked chromatin opening. Cell Metabolism, 36 (8), 1858-1881.e23. doi: 10.1016/j.cmet.2024.06.006

The activity of early-life gene regulatory elements is hijacked in aging through pervasive AP-1-linked chromatin opening

2024

Journal Article

Wnt dose escalation during the exit from pluripotency identifies tranilast as a regulator of cardiac mesoderm

Wu, Zhixuan, Shen, Sophie, Mizikovsky, Dalia, Cao, Yuanzhao, Naval-Sanchez, Marina, Tan, Siew Zhuan, Alvarez, Yanina D., Sun, Yuliangzi, Chen, Xiaoli, Zhao, Qiongyi, Kim, Daniel, Yang, Pengyi, Hill, Timothy A., Jones, Alun, Fairlie, David P., Pébay, Alice, Hewitt, Alex W., Tam, Patrick P.L., White, Melanie D., Nefzger, Christian M. and Palpant, Nathan J. (2024). Wnt dose escalation during the exit from pluripotency identifies tranilast as a regulator of cardiac mesoderm. Developmental Cell, 59 (6), 705-722.e8. doi: 10.1016/j.devcel.2024.01.019

Wnt dose escalation during the exit from pluripotency identifies tranilast as a regulator of cardiac mesoderm

2023

Journal Article

Micrococcal nuclease sequencing of porcine sperm suggests enriched co-location between retained histones and genomic regions related to semen quality and early embryo development

Gòdia, Marta, Lian, Yu, Naval-Sanchez, Marina, Ponte, Inma, Rodríguez-Gil, Joan Enric, Sanchez, Armand and Clop, Alex (2023). Micrococcal nuclease sequencing of porcine sperm suggests enriched co-location between retained histones and genomic regions related to semen quality and early embryo development. PeerJ, 11 e15520, 1-25. doi: 10.7717/peerj.15520

Micrococcal nuclease sequencing of porcine sperm suggests enriched co-location between retained histones and genomic regions related to semen quality and early embryo development

2022

Journal Article

Leveraging transcriptome and epigenome landscapes to infer regulatory networks during the onset of sexual maturation

Mohamed, Amin R., Naval-Sanchez, Marina, Menzies, Moira, Evans, Bradley, King, Harry, Reverter, Antonio and Kijas, James W. (2022). Leveraging transcriptome and epigenome landscapes to infer regulatory networks during the onset of sexual maturation. BMC Genomics, 23 (1) 413, 1-19. doi: 10.1186/s12864-022-08514-8

Leveraging transcriptome and epigenome landscapes to infer regulatory networks during the onset of sexual maturation

2022

Journal Article

Organization of gene programs revealed by unsupervised analysis of diverse gene–trait associations

Mizikovsky, Dalia, Naval Sanchez, Marina, Nefzger, Christian M, Cuellar Partida, Gabriel and Palpant, Nathan J (2022). Organization of gene programs revealed by unsupervised analysis of diverse gene–trait associations. Nucleic Acids Research, 50 (15) e87, 1-12. doi: 10.1093/nar/gkac413

Organization of gene programs revealed by unsupervised analysis of diverse gene–trait associations

2022

Journal Article

Benchmarking of ATAC Sequencing Data From BGI’s Low-Cost DNBSEQ-G400 Instrument for Identification of Open and Occupied Chromatin Regions

Naval-Sanchez, Marina, Deshpande, Nikita, Tran, Minh, Zhang, Jingyu, Alhomrani, Majid, Alsanie, Walaa, Nguyen, Quan and Nefzger, Christian M. (2022). Benchmarking of ATAC Sequencing Data From BGI’s Low-Cost DNBSEQ-G400 Instrument for Identification of Open and Occupied Chromatin Regions. Frontiers in Molecular Biosciences, 9 900323, 1-15. doi: 10.3389/fmolb.2022.900323

Benchmarking of ATAC Sequencing Data From BGI’s Low-Cost DNBSEQ-G400 Instrument for Identification of Open and Occupied Chromatin Regions

2022

Journal Article

Temporal perturbation of histone deacetylase activity reveals a requirement for HDAC1–3 in mesendoderm cell differentiation

Sinniah, Enakshi, Wu, Zhixuan, Shen, Sophie, Naval-Sanchez, Marina, Chen, Xiaoli, Lim, Junxian, Helfer, Abbigail, Iyer, Abishek, Tng, Jiahui, Lucke, Andrew J., Reid, Robert C., Redd, Meredith A., Nefzger, Christian M., Fairlie, David P. and Palpant, Nathan J. (2022). Temporal perturbation of histone deacetylase activity reveals a requirement for HDAC1–3 in mesendoderm cell differentiation. Cell Reports, 39 (7) 110818, 1-21. doi: 10.1016/j.celrep.2022.110818

Temporal perturbation of histone deacetylase activity reveals a requirement for HDAC1–3 in mesendoderm cell differentiation

2021

Journal Article

Chromatin accessibility and regulatory vocabulary across indicine cattle tissues

Alexandre, Pâmela A., Naval-Sánchez, Marina, Menzies, Moira, Nguyen, Loan T., Porto-Neto, Laercio R., Fortes, Marina R. S. and Reverter, Antonio (2021). Chromatin accessibility and regulatory vocabulary across indicine cattle tissues. Genome Biology, 22 (1) 273, 273. doi: 10.1186/s13059-021-02489-7

Chromatin accessibility and regulatory vocabulary across indicine cattle tissues

2021

Conference Publication

Chromatin accessibility and regulatory vocabulary in indicine cattle

Alexandre, Pâmela A., Naval-Sánchez, Marina, Menzies, Moira, Nguyen, Loan T., Porto-Neto, Laercio, Fortes, Marina R.S. and Reverter, Antonio (2021). Chromatin accessibility and regulatory vocabulary in indicine cattle. 38th International Society of Animal Genetics (ISAG), Virtual, 26-30 July 2021. Champaign, IL United States: ISAG.

Chromatin accessibility and regulatory vocabulary in indicine cattle

2021

Journal Article

A conserved haplotype in Wagyu cattle contains RAB4A whose encoded protein regulates glucose trafficking in muscle and fat cells

Hudson, N. J., Porto-Neto, L., Naval-Sanchez, M., Lyons, R. E. and Reverter, Antonio (2021). A conserved haplotype in Wagyu cattle contains RAB4A whose encoded protein regulates glucose trafficking in muscle and fat cells. Animal Genetics, 52 (3), 275-283. doi: 10.1111/age.13054

A conserved haplotype in Wagyu cattle contains RAB4A whose encoded protein regulates glucose trafficking in muscle and fat cells

2021

Journal Article

Analysis of polycerate mutants reveals the evolutionary co-option of HOXD1 for horn patterning in Bovidae

Allais-Bonnet, Aurélie, Hintermann, Aurélie, Deloche, Marie-Christine, Cornette, Raphaël, Bardou, Philippe, Naval-Sanchez, Marina, Pinton, Alain, Haruda, Ashleigh, Grohs, Cécile, Zakany, Jozsef, Bigi, Daniele, Medugorac, Ivica, Putelat, Olivier, Greyvenstein, Ockert, Hadfield, Tracy, Jemaa, Slim Ben, Bunevski, Gjoko, Menzi, Fiona, Hirter, Nathalie, Paris, Julia M., Hedges, John, Palhiere, Isabelle, Rupp, Rachel, Lenstra, Johannes A., Gidney, Louisa, Lesur, Joséphine, Schafberg, Renate, Stache, Michael, Wandhammer, Marie-Dominique ... Capitan, Aurélien (2021). Analysis of polycerate mutants reveals the evolutionary co-option of HOXD1 for horn patterning in Bovidae. Molecular Biology and Evolution, 38 (6), 2260-2272. doi: 10.1093/molbev/msab021

Analysis of polycerate mutants reveals the evolutionary co-option of HOXD1 for horn patterning in Bovidae

2021

Journal Article

Nicotinamide riboside attenuates age-associated metabolic and functional changes in hematopoietic stem cells

Sun, Xuan, Cao, Benjamin, Naval-Sanchez, Marina, Pham, Tony, Sun, Yu Bo Yang, Williams, Brenda, Heazlewood, Shen Y, Deshpande, Nikita, Li, Jinhua, Kraus, Felix, Rae, James, Nguyen, Quan, Yari, Hamed, Schröder, Jan, Heazlewood, Chad K, Fulton, Madeline, Hatwell-Humble, Jessica, Das Gupta, Kaustav, Kapetanovic, Ronan, Chen, Xiaoli, Sweet, Matthew J, Parton, Robert G, Ryan, Michael T, Polo, Jose M, Nefzger, Christian M and Nilsson, Susan K (2021). Nicotinamide riboside attenuates age-associated metabolic and functional changes in hematopoietic stem cells. Nature Communications, 12 (1) 2665, 1-17. doi: 10.1038/s41467-021-22863-0

Nicotinamide riboside attenuates age-associated metabolic and functional changes in hematopoietic stem cells

2020

Journal Article

Genome-wide co-expression distributions as a metric to prioritize genes of functional importance

Alexandre, Pâmela A., Hudson, Nicholas J., Lehnert, Sigrid A., Fortes, Marina R. S., Naval-Sánchez, Marina, Nguyen, Loan T., Porto-Neto, Laercio R. and Reverter, Antonio (2020). Genome-wide co-expression distributions as a metric to prioritize genes of functional importance. Genes, 11 (10) 1231, 1231-13. doi: 10.3390/genes11101231

Genome-wide co-expression distributions as a metric to prioritize genes of functional importance

2020

Journal Article

Selection signatures in tropical cattle are enriched for promoter and coding regions and reveal missense mutations in the damage response gene HELB

Naval-Sánchez, Marina, Porto-Neto, Laercio R., Cardoso, Diercles F., Hayes, Ben J., Daetwyler, Hans D., Kijas, James and Reverter, Antonio (2020). Selection signatures in tropical cattle are enriched for promoter and coding regions and reveal missense mutations in the damage response gene HELB. Genetics Selection Evolution, 52 (1) 27, 27. doi: 10.1186/s12711-020-00546-6

Selection signatures in tropical cattle are enriched for promoter and coding regions and reveal missense mutations in the damage response gene HELB

2020

Journal Article

Dynamics of gene co-expression networks in time-series data: a case study in Drosophila melanogaster embryogenesis

Lau, Li Yieng, Reverter, Antonio, Hudson, Nicholas J., Naval-Sanchez, Marina, Fortes, Marina R. S. and Alexandre, Pâmela A. (2020). Dynamics of gene co-expression networks in time-series data: a case study in Drosophila melanogaster embryogenesis. Frontiers in Genetics, 11 517, 517. doi: 10.3389/fgene.2020.00517

Dynamics of gene co-expression networks in time-series data: a case study in Drosophila melanogaster embryogenesis

2020

Journal Article

Changed Patterns of Genomic Variation Following Recent Domestication: Selection Sweeps in Farmed Atlantic Salmon

Naval-Sanchez, Marina, McWilliam, Sean, Evans, Bradley, Yáñez, José M., Houston, Ross D. and Kijas, James W. (2020). Changed Patterns of Genomic Variation Following Recent Domestication: Selection Sweeps in Farmed Atlantic Salmon. Frontiers in Genetics, 11 264. doi: 10.3389/fgene.2020.00264

Changed Patterns of Genomic Variation Following Recent Domestication: Selection Sweeps in Farmed Atlantic Salmon

2020

Journal Article

Association analysis of loci implied in 'buffering' epistasis

Reverter, Antonio, Vitezica, Zulma G., Naval-Sánchez, Marina, Henshall, John, Raidan, Fernanda, Li, Yutao, Meyer, Karin, Hudson, Nicholas J., Porto-Neto, Laercio R. and Legarra, Andrés (2020). Association analysis of loci implied in 'buffering' epistasis. Journal of Animal Science, 98 (3) skaa045. doi: 10.1093/jas/skaa045

Association analysis of loci implied in 'buffering' epistasis

2019

Journal Article

Systems biology reveals NR2F6 and TGFB1 as key regulators of feed efficiency in beef cattle

Alexandre, Pâmela A., Naval-Sanchez, Marina, Porto-Neto, Laercio R., Ferraz, José Bento S., Reverter, Antonio and Fukumasu, Heidge (2019). Systems biology reveals NR2F6 and TGFB1 as key regulators of feed efficiency in beef cattle. Frontiers in Genetics, 10 (MAR) 230. doi: 10.3389/fgene.2019.00230

Systems biology reveals NR2F6 and TGFB1 as key regulators of feed efficiency in beef cattle

2018

Journal Article

Correction: Amniotic ectoderm expansion in mouse occurs via distinct modes and requires SMAD5-mediated signalling (vol 145, dev157222, 2018)

Dobreva, Mariya P., Escalona, Vanesa Abon, Lawson, Kirstie A., Sanchez, Marina N., Ponomarev, Ljuba C., Pereira, Paulo N. G., Stryjewska, Agata, Criem, Nathan, Huylebroeck, Danny, Lopes, Susana M. Chuva de Sousa, Aerts, Stein and Zwijsen, An (2018). Correction: Amniotic ectoderm expansion in mouse occurs via distinct modes and requires SMAD5-mediated signalling (vol 145, dev157222, 2018). Development, 145 (15). doi: 10.1242/dev.169722

Correction: Amniotic ectoderm expansion in mouse occurs via distinct modes and requires SMAD5-mediated signalling (vol 145, dev157222, 2018)

Funding

Current funding

  • 2025 - 2029
    Deciphering the gene regulatory code of ageing to set the stage for therapeutic intervention
    NHMRC Investigator Grants
    Open grant

Past funding

  • 2021 - 2022
    Dr Marina Naval Sanchez - AQ WRAP
    Advance Queensland Women's Research Assistance Program
    Open grant

Supervision

Availability

Dr Marina Naval Sanchez is:
Available for supervision

Before you email them, read our advice on how to contact a supervisor.

Available projects

Supervision history

Current supervision

  • Doctor Philosophy

    Development of a multimodal single-cell assay reveals somatic NFI transcription factors as dose-dependent pluripotency mediators

    Associate Advisor

    Other advisors: Professor Matt Sweet, Dr Christian Nefzger

  • Doctor Philosophy

    Deciphering the age-altered transcription factor network and its control over regenerative potential

    Associate Advisor

    Other advisors: Dr Quan Nguyen, Dr Christian Nefzger

  • Doctor Philosophy

    Leveraging integrative multiomic data to enable controlled cell state transition

    Associate Advisor

    Other advisors: Professor Matt Sweet, Dr Christian Nefzger

  • Doctor Philosophy

    Leveraging integrative multiomic data to enable controlled cell state transition

    Associate Advisor

    Other advisors: Professor Matt Sweet, Dr Christian Nefzger

  • Doctor Philosophy

    Network reinforcement to improve the function of aged cells

    Associate Advisor

    Other advisors: Dr Christian Nefzger

Media

Enquiries

For media enquiries about Dr Marina Naval Sanchez's areas of expertise, story ideas and help finding experts, contact our Media team:

communications@uq.edu.au