Overview
Background
I am a clinician-academic whose interactions with patients have shaped my research questions and fuelled my enthusiasm for the importance of clinical research. I trained as a genetic counsellor and my research now focuses on the integration of genomics into clinical care. My research program has had three primary themes: evaluating the psychosocial impact of genetic conditions and/or genetic testing; evaluating genetics education preferences for patients and healthcare providers; and using next-generation sequencing to increase diagnostic yield for rare disorders.
Current research projects include:
- Exploring whether genetic fatalism affects sun-related health behaviours in high-risk individuals following genetic testing.
- Exploring the referral journey to genetic services for individuals with rare diseases
- Assessing Human Research Ethics Committee (HREC) members’ confidence in reviewing genomic research applications.
- Mainstreaming Genetic Testing for Melanoma into Dermatology Practice.
- Using Exome sequencing to identify new genes in families with inherited melanoma, negative for mutations in known genes.
Availability
- Associate Professor Aideen McInerney-Leo is:
- Available for supervision
Qualifications
- Masters (Coursework) of Science, The University of Manchester
- Doctor of Philosophy, The University of Queensland
Research interests
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Integrating genetic testing for melanoma into dermatology practice
Our study explores whether upskilling dermatologists to offer genetic testing for melanoma is acceptable to dermatologists and whether patient outcomes, as compared to when genetic testing is offered by a genetic counsellor.
Works
Search Professor Aideen McInerney-Leo’s works on UQ eSpace
2011
Conference Publication
Complete Exome Sequencing for Marfan Syndrome, Osteogenesis Imperfecta and Stickler Syndrome: a New Era
McInerney-Leo, A., Glasov, E., Duncan, E. and Zankl, A. (2011). Complete Exome Sequencing for Marfan Syndrome, Osteogenesis Imperfecta and Stickler Syndrome: a New Era. Rheumatology Health Professionals Association 52nd Annual Scientific Meeting, Brisbane, Queensland, 14-17 May 2011. Richmond, VIC, Australia: Wiley-Blackwell. doi: 10.1111/j.1445-5994.2010.02467.x
2007
Journal Article
Comprehensive screening of a north American Parkinson's disease cohort for LRRK2 mutation
Johnson, Janel, Paisan-Ruiz, Coro, Lopez, Grisel, Crews, Cynthia, Britton, Angela, Malkani, Roniel, Evans, E. Whitney, McInerney-Leo, Aideen, Jain, Shushant, Nussbaum, Robert L., Foote, Kelly D., Mandel, Ronald J., Crawley, Anthony, Reimsnider, Sharon, Fernandez, Hubert H., Okun, Michael S., Gwinn-Hardy, Katrina and Singleton, Andrew B. (2007). Comprehensive screening of a north American Parkinson's disease cohort for LRRK2 mutation. Neurodegenerative Diseases, 4 (5), 386-391. doi: 10.1159/000105160
2006
Journal Article
BRCA1/2 testing in hereditary breast and ovarian cancer families III: risk perception and screening
McInerney-Leo, Aideen, Hadley, Donald, Kase, Ronald G., Giambarresi, Therese R., Struewing, Jeffery P. and Biesecker, Barbara Bowles (2006). BRCA1/2 testing in hereditary breast and ovarian cancer families III: risk perception and screening. American Journal of Medical Genetics Part A, 140A (20), 2198-2206. doi: 10.1002/ajmg.a.31432
2006
Journal Article
Truth-telling and Turner syndrome: the importance of diagnostic disclosure
Sutton, Erica J., Young, Jessica, McInerney-Leo, Aideen, Bondy, Carolyn A., Gollust, Sarah E. and Biesecker, Barbara B. (2006). Truth-telling and Turner syndrome: the importance of diagnostic disclosure. Journal of Pediatrics, 148 (1), 102-107. doi: 10.1016/j.jpeds.2005.08.022
2005
Journal Article
Turner syndrome: four challenges across the lifespan
Sutton, Erica J., McInerney-Leo, Aideen, Bondy, Carolyn A., Gollust, Sarah E., King, Donnice and Biesecker, Barbara (2005). Turner syndrome: four challenges across the lifespan. American Journal of Medical Genetics Part A, 139A (2), 57-66. doi: 10.1002/ajmg.a.30911
2005
Journal Article
Analysis of SCA-2 and SCA-3 repeats in Parkinsonism: evidence of SCA-2 expansion in a family with autosomal dominant Parkinson's disease
Simon-Sanchez, Javier, Hanson, Melissa, Singleton, Amanda, Hernandez, Dena, McInerney, Aideen, Nussbaum, Robert, Werner, John, Gallardo, Marisol, Weiser, Roberto, Gwinn-Hardy, Katrina, Singleton, Andrew B. and Clarimon, Jordi (2005). Analysis of SCA-2 and SCA-3 repeats in Parkinsonism: evidence of SCA-2 expansion in a family with autosomal dominant Parkinson's disease. Neuroscience Letters, 382 (1-2), 191-194. doi: 10.1016/j.neulet.2005.03.015
2005
Journal Article
Midbrain dopamine and prefrontal function in humans: interaction and modulation by COMT genotype
Meyer-Lindenberg, Andreas, Kohn, Philip D., Kolachana, Bhaskar, Kippenhan, Shane, McInerney-Leo, Aideen, Nussbaum, Robert, Weinberger, Daniel R. and Berman, Karen Faith (2005). Midbrain dopamine and prefrontal function in humans: interaction and modulation by COMT genotype. Nature Neuroscience, 8 (5), 594-596. doi: 10.1038/nn1438
2005
Journal Article
BRCA1/2 testing in hereditary breast and ovarian cancer families II: impact on relationships
McInerney‐Leo, Aideen, Biesecker, Barbara Bowles, Hadley, Donald W., Kase, Ronald G., Giambarresi, Therese R., Johnson, Elizabeth, Lerman, Caryn and Struewing, Jeffery P. (2005). BRCA1/2 testing in hereditary breast and ovarian cancer families II: impact on relationships. American Journal of Medical Genetics Part A, 133A (2), 165-169. doi: 10.1002/ajmg.a.30566
2005
Journal Article
Clinical and positron emission tomography of Parkinson's disease caused by LRRK2
Hernandez, Dena G., Paisan-Ruiz, Coro, McInerney-Leo, Aideen, Jain, Shushant, Meyer-Lindenberg, Andreas, Evans, E. Whitney, Berman, Karen F., Johnson, Janel, Auburger, Georg, Schaffer, Alejandro A., Lopez, Grisel J., Nussbaum, Robert L. and Singleton, Andrew B. (2005). Clinical and positron emission tomography of Parkinson's disease caused by LRRK2. Annals of Neurology, 57 (3), 453-456. doi: 10.1002/ana.20401
2005
Journal Article
Genetic testing in Parkinson's disease
McInerney-Leo, Aideen, Hadley, Donald W., Gwinn-Hardy, Katrina and Hardy, John (2005). Genetic testing in Parkinson's disease. Movement Disorders, 20 (1), 1-10. doi: 10.1002/mds.20316
2005
Journal Article
Genetic testing in Parkinson's disease
McInerney-Leo, Aideen (2005). Genetic testing in Parkinson's disease. Movement Disorders, 20 (7), 908-909. doi: 10.1002/mds.20509
2004
Journal Article
Analysis of the PINK1 gene in a large cohort of cases with Parkinson disease
Rogaeva, E., Johnson, J., Lang, A. E., Gulick, C., Gwinn-Hardy, K., Kawarai, T., Sato, C., Morgan, A., Werner, J., Nussbaum, R., Petit, A., Okun, M. S., McInerney, A., Mandel, R., Groen, J. L., Fernandez, H. H., Postuma, R., Foote, K. D., Salehi-Rad, S., Liang, Y., Reimsnider, S., Tandon, A., Hardy, J., St George-Hyslop, P. and Singleton, A. B. (2004). Analysis of the PINK1 gene in a large cohort of cases with Parkinson disease. Archives of Neurology, 61 (12), 1898-1904. doi: 10.1001/archneur.61.12.1898
2004
Journal Article
Parkinsonism among Gaucher disease carriers
Goker-Alpan, O., Schiffmann, R., LaMarca, M.E., Nussbaum, R.L., McInerney-Leo, A. and Sidransky, E. (2004). Parkinsonism among Gaucher disease carriers. Journal of Medical Genetics, 41 (12), 937-940. doi: 10.1136/jmg.2004.024455
2004
Journal Article
BRCA1/2 testing in hereditary breast and ovarian cancer families: effectiveness of problem-solving training as a counseling intervention
McInerney-Leo, Aideen, Biesecker, Barbara Bowles, Hadley, Donald W., Kase, Ronald G., Giambarresi, Therese R., Johnson, Elizabeth, Lerman, Caryn and Struewing, Jeffery P. (2004). BRCA1/2 testing in hereditary breast and ovarian cancer families: effectiveness of problem-solving training as a counseling intervention. American Journal of Medical Genetics Part A, 130A (3), 221-227. doi: 10.1002/ajmg.a.30265
2004
Journal Article
SNCA multiplication is not a common cause of Parkinson disease or dementia with Lewy bodies
Johnson, J., Hague, S. M., Hanson, M., Gibson, A., Wilson, K. E., Evans, E. W., Singleton, A. A., McInerney-Leo, A., Nussbaum, R. L., Hernandez, D. G., Gallardo, M., McKeith, I. G., Burn, D. J., Ryu, M., Hellstrom, O., Ravina, B., Eerola, J., Perry, R. H., Jaros, E., Tienari, P., Weiser, R., Gwinn-Hardy, K., Morris, C. M., Hardy, J. and Singleton, A. B. (2004). SNCA multiplication is not a common cause of Parkinson disease or dementia with Lewy bodies. Neurology, 63 (3), 554-556. doi: 10.1212/01.WNL.0000133401.09043.44
2004
Journal Article
Prevalence of Parkinson's disease in populations of African ancestry: a review
McInerney-Leo, Aideen, Gwinn-Hardy, Katrina and Nussbaum, Robert L. (2004). Prevalence of Parkinson's disease in populations of African ancestry: a review. Journal of the National Medical Association, 96 (7), 974-979.
2001
Journal Article
Hemifacial microsomia: progress in understanding the genetic basis of a complex malformation syndrome
Kelberman, D., Tyson, J., Chandler, D. C., McInerney, A. M., Slee, J., Albert, D., Aymat, A., Botma, M., Calvert, M., Goldblatt, J., Haan, E. A., Laing, N. G., Lim, J., Malcolm, S., Singer, S. L., Winter, R. M. and Bitner-Glindzicz, M. (2001). Hemifacial microsomia: progress in understanding the genetic basis of a complex malformation syndrome. Human Genetics, 109 (6), 638-645. doi: 10.1007/s00439-001-0626-x
2001
Journal Article
Education about genetic testing for breast cancer susceptibility: patient preferences for a computer program or genetic counselor
Green, Michael J., McInerney, Aideen M., Biesecker, Barbara B. and Fost, Norman (2001). Education about genetic testing for breast cancer susceptibility: patient preferences for a computer program or genetic counselor. American Journal of Medical Genetics, 103 (1), 24-31. doi: 10.1002/ajmg.1501
2001
Journal Article
An interactive computer program can effectively educate patients about genetic testing for breast cancer susceptibility
Green, Michael J., Biesecker, Barbara B., McInerney, Aideen M., Mauger, David and Fost, Norman (2001). An interactive computer program can effectively educate patients about genetic testing for breast cancer susceptibility. American Journal of Medical Genetics, 103 (1), 16-23. doi: 10.1002/ajmg.1500
2000
Journal Article
Minocycline-induced generalized postinflammatory elastolysis
Ho, Nicola C, McInerney, Aideen, Levy, Howard, Francomano, Clair A and Elkayam, Ori (2000). Minocycline-induced generalized postinflammatory elastolysis. The American Journal of Medicine, 109 (4), 340-340. doi: 10.1016/s0002-9343(00)00499-x
Funding
Current funding
Past funding
Supervision
Availability
- Associate Professor Aideen McInerney-Leo is:
- Available for supervision
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Supervision history
Current supervision
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Doctor Philosophy
Integrating genomics and deep phenotyping to optimise care for paediatric hearing loss
Principal Advisor
-
Doctor Philosophy
Unusual suspects in hereditary melanoma: phenotype-genotype characterisation of POT1, POLE, BAP1 and CDKN2A carriers
Principal Advisor
Other advisors: Professor Peter Soyer, Dr Brigid Betz-Stablein
-
Doctor Philosophy
Development and evaluation of model of care for implementation of genomic testing for paediatric healthcare
Associate Advisor
Other advisors: Dr Tatiane Yanes
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Doctor Philosophy
Mainstreaming polygenic risk testing for common cancers into clinical practice
Associate Advisor
Other advisors: Dr Tatiane Yanes
-
Doctor Philosophy
Artificial Intelligence Tools for Automated Melanoma Risk Assessment: Potential Utility and Validation
Associate Advisor
Other advisors: Dr Brigid Betz-Stablein, Professor Peter Soyer
-
Doctor Philosophy
Translating polygenic and personalised risk scores: Acceptability and impact of providing polygenic and personalised risk information for melanoma
Associate Advisor
Other advisors: Professor Peter Soyer, Dr Tatiane Yanes
Completed supervision
-
2023
Doctor Philosophy
Mainstreaming Genetic Testing for Familial Melanoma: evaluating whether psycho-behavioural outcomes differ depending on provider type
Principal Advisor
Other advisors: Dr Anna Finnane, Professor Peter Soyer
Media
Enquiries
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