Professor Ian Yang
Professor

Ian Yang

Email: 
Phone: 
+61 7 3139 5050

Background

Professor Ian Yang is a Thoracic Physician and Director of Thoracic Medicine at The Prince Charles Hospital, and Head of the PCH-Northside Clinical Unit, School of Clinical Medicine, Faculty of Medicine, The University of Queensland, Brisbane, Australia.

Availability

Professor Ian Yang is:
Available for supervision

Fields of research

Biomedical and Clinical Sciences Cardiovascular medicine and haematology Clinical sciences Oncology and carcinogenesis Respiratory diseases

Qualifications

  • Bachelor (Honours) of Medicine Surgery, The University of Queensland
  • Postgraduate Diploma, University of Newcastle
  • Doctor of Philosophy, The University of Queensland
  • Asian Pacific Society of Respirology, Asian Pacific Society of Respirology
  • Royal Australasian College of Physicians, Royal Australasian College of Physicians
  • The Thoracic Society of Australia and New Zealand, The Thoracic Society of Australia and New Zealand

Research interests

  • Clinical and translational research in chronic lung diseases

    Pathogenesis, diagnosis and treatment of chronic lung diseases, including COPD, asthma, lung cancer, mesothelioma and effects of air pollution

Research impacts

His clinical work is in the field of thoracic medicine, and his research team is studying gene-environmental interaction in COPD, asthma, lung cancer and air pollution. He is involved in the training of higher degree students in translational research into lung diseases.

He is a Chair of the National COPD Guidelines Committee of the Lung Foundation Australia, and a member of the COPD Coordinating Committee. He is Chair of the Medical Programs and Research Advisory Committee of the Asthma Foundation Queensland NSW.

Search Professor Ian Yang’s works on UQ eSpace

360 works between 1999 and 2025
All (360) Journal Article (265) Book Chapter (10) Conference Publication (84) Other Outputs (1)

341 - 360 of 360 works

2004

Journal Article

Characterization of two polymorphisms in the leukotriene C4 synthase gene in an Australian population of subjects with mild, moderate, and severe asthma

Kedda, MA, Shi, J, Duffy, D, Phelps, S, Yang, I, O'Hara, K, Fong, K and Thompson, PJ (2004). Characterization of two polymorphisms in the leukotriene C4 synthase gene in an Australian population of subjects with mild, moderate, and severe asthma. Journal of Allergy & Clinical Immunology, 113 (5), 889-895. doi: 10.1016/j.jaci.2004.02.008

Characterization of two polymorphisms in the leukotriene C4 synthase gene in an Australian population of subjects with mild, moderate, and severe asthma

2003

Journal Article

Mannose-binding lectin gene polymorphism predicts hospital admissions for COPD infections

Yang, I. A., Seeney, S. L., Wolter, J. M., Anders, E. M., McCormack, J. G., Tunnicliffe, A. M., Rabnott, G. C., Shaw, J. G., Dent, A. G., Kim, S. T., Zimmerman, P. V. and Fong, K. M. (2003). Mannose-binding lectin gene polymorphism predicts hospital admissions for COPD infections. Genes & Immunity, 4 (4), 269-274. doi: 10.1038/sj.gene.6363961

Mannose-binding lectin gene polymorphism predicts hospital admissions for COPD infections

2003

Journal Article

Polymorphisms in Toll-like receptor 4 and the systemic inflammatory response syndrome

Child, NJA, Yang, IA, Pulletz, MCK, de Courcy-Golder, K, Andrews, AL, Pappachan, VJ and Holloway, JW (2003). Polymorphisms in Toll-like receptor 4 and the systemic inflammatory response syndrome. Biochemical Society Transactions, 31 (3), 652-653. doi: 10.1042/BST0310652

Polymorphisms in Toll-like receptor 4 and the systemic inflammatory response syndrome

2003

Journal Article

(-)-CGP 12177 increases contractile force and hastens relaxation of human myocardial preparations through a propranolol-resistant state of the beta1-adrenoceptor

Sarsero, Doreen, Russell, Fraser D., Lynham, James A., Rabnott, Glenn, Yang, Ian, Fong, Kwun M., Li, Li, Kaumann, Alberto J. and Molenaar, Peter (2003). (-)-CGP 12177 increases contractile force and hastens relaxation of human myocardial preparations through a propranolol-resistant state of the beta1-adrenoceptor. Naunyn-Schmiedeberg's Archives of Pharmacology, 367 (1), 10-21. doi: 10.1007/s00210-002-0652-9

(-)-CGP 12177 increases contractile force and hastens relaxation of human myocardial preparations through a propranolol-resistant state of the beta1-adrenoceptor

2003

Journal Article

TLR4 Asp299Gly polymorphism is not associated with coronary artery stenosis

Yang, Ian A., Holloway, John W. and Ye, Shu (2003). TLR4 Asp299Gly polymorphism is not associated with coronary artery stenosis. Atherosclerosis, 170 (1), 187-190. doi: 10.1016/S0021-9150(03)00286-7

TLR4 Asp299Gly polymorphism is not associated with coronary artery stenosis

2002

Conference Publication

The positive inotropic effects of norepinephrine are potentiated by chronic beta1-blocker administration but are conserved across Ser49Gly- and Gly389Arg-beta1-adrenergic receptor polymorphisms in human right atrium

Molenaar, P., Russell, F. D., Rabnott, G., Yang, I., Fong, K. M., Savarimuthu, S. M., Li, L. and West, M. J. (2002). The positive inotropic effects of norepinephrine are potentiated by chronic beta1-blocker administration but are conserved across Ser49Gly- and Gly389Arg-beta1-adrenergic receptor polymorphisms in human right atrium. American Heart Association Scientific Sessions 2002, Chicago, 17-20 Nov, 2002. Hagerstown, U.S.A.: Lippincott Williams & Wilkins.

The positive inotropic effects of norepinephrine are potentiated by chronic beta1-blocker administration but are conserved across Ser49Gly- and Gly389Arg-beta1-adrenergic receptor polymorphisms in human right atrium

2002

Journal Article

Conservation of the cardiostimulant effects of (-)-Norepinephrine across Ser49Gly and Gly389Arg Beta1-adrenergic receptor polymorphisms in human right atrium in vitro

Molenaar, P., Rabnott, G., Yang, I., Fong, K. M., Savarimuthu, S. M., Li, L., West, M. J. and Russell, F. D. (2002). Conservation of the cardiostimulant effects of (-)-Norepinephrine across Ser49Gly and Gly389Arg Beta1-adrenergic receptor polymorphisms in human right atrium in vitro. Journal of The American College of Cardiology, 40 (7), 1275-1282. doi: 10.1016/S0735-1097(02)02137-X

Conservation of the cardiostimulant effects of (-)-Norepinephrine across Ser49Gly and Gly389Arg Beta1-adrenergic receptor polymorphisms in human right atrium in vitro

2002

Other Outputs

Genetic variation in COPD pathogenesis

Yang, Ian Anthony (2002). Genetic variation in COPD pathogenesis. PhD Thesis, School of Medicine, The University of Queensland. doi: 10.14264/106084

Genetic variation in COPD pathogenesis

2000

Conference Publication

Tumour necrosis factor (TNF ), myeloperoxides (MPO) and interleukin-1 receptor antagonist polymorphisms in cystic fibrosis.

Gan, R., Bowler, S. D., Seeney, S. L., Wolter, J.M., Masel, P. J., Bunting, J., Tunnicliffe, A. M., Rabnott, G. C., Yang, I. A. and Bell, S. (2000). Tumour necrosis factor (TNF ), myeloperoxides (MPO) and interleukin-1 receptor antagonist polymorphisms in cystic fibrosis.. Fourteenth Annual North American Cystic Fibrosis Conference, Baltimore Maryland, USA, 9-12 Novewmber, 2000. New York USA: Wiley-Liss.

Tumour necrosis factor (TNF ), myeloperoxides (MPO) and interleukin-1 receptor antagonist polymorphisms in cystic fibrosis.

2000

Conference Publication

Azithromycin (AZM) reduces TNF- release from lipopolysachcharide (LPS) - stimulated mononuclear cells (PBMC) in cystic fibrosis

Bell, S., Wolter, J. M., Seeney, S. L., Gan, R., Yang, I., Bowler, S. D. and Mccormack, J. G. (2000). Azithromycin (AZM) reduces TNF- release from lipopolysachcharide (LPS) - stimulated mononuclear cells (PBMC) in cystic fibrosis. Fourteenth Annual North American Cystic Fibrosis Conference, Baltimore Maryland, USA, 9-12 Novembe, 2000. New York, USA: Wiley Liss, Div John Wiley & Sons.

Azithromycin (AZM) reduces TNF- release from lipopolysachcharide (LPS) - stimulated mononuclear cells (PBMC) in cystic fibrosis

2000

Conference Publication

Azithromycin (AZM) reduced TNF- release from lipopolysachharide (LPS)-stimulated mononuclear cells (PBMC) in cystic fibrosis (CF)

Wolter, J. M., Seeney, S. L., Yang, I. A., Bowler, S. D., Bell, S. and Mccormack, J. G. (2000). Azithromycin (AZM) reduced TNF- release from lipopolysachharide (LPS)-stimulated mononuclear cells (PBMC) in cystic fibrosis (CF). ASID Annual Scientific Meeting, Laura, NSW, 15-19 April, 2001. Balgowlah NSW: ADIS Press Australia.

Azithromycin (AZM) reduced TNF- release from lipopolysachharide (LPS)-stimulated mononuclear cells (PBMC) in cystic fibrosis (CF)

1999

Conference Publication

GSTM1 and GSTT1 genotypes in Australians with NSCLC

Gan, R., Yang, I. A., Tunnicliffe, A. M., Rabnott, G. C. and Fong, K. M. (1999). GSTM1 and GSTT1 genotypes in Australians with NSCLC. Pulmonary-Renal Interface, Hyatt Regency Sanctuary Cove, 26 - 28 Nov, 1999. Qld.: Thoracic Society.

GSTM1 and GSTT1 genotypes in Australians with NSCLC

1999

Conference Publication

b2 adrenergic receptor genotypes in severe asthma

Douglas, J. A., Yang, I., Rabnott, G. C., Tunnicliffe, A. M., McCarthy, J. B., Zimmerman, P. V. and Fong, K. M. (1999). b2 adrenergic receptor genotypes in severe asthma. Heart and Lungs, Canberra, 26 Feb - 3 March 1999. Carlton, Vic.: Blackwell Science.

b2 adrenergic receptor genotypes in severe asthma

1999

Conference Publication

b2 adrenoceptor genotypes and life-threatening asthma

Rabnott, G. C., Tunnicliffe, A. M., Yang, I. A., Douglas, J. A., Shaw, J., McCarthy, J. B., Zimmerman, P. V. and Fong, K. M. (1999). b2 adrenoceptor genotypes and life-threatening asthma. Pulmonary-Renal Interface, Hyatt Regency Sanctuary Cove, 26 - 28 Nov, 1999. Qld.: Thoracic Society of Qld..

b2 adrenoceptor genotypes and life-threatening asthma

1999

Conference Publication

GSTT1 and GSTM1 polymorphisms in Australian chronic obstructive pulmonary disease (COPD) patients

Yang, I. A., Gan, R., Tunniclife, A. M., Rabnott, G. C., Zimmerman, P.V. and Fong, K. M. (1999). GSTT1 and GSTM1 polymorphisms in Australian chronic obstructive pulmonary disease (COPD) patients. European Society Annual Congress, Madrid, Spain, 9 - 13 Oct, 1999. Copenhagen, Denmark: European Respiratory Society & Munksgaard Int. Publishers.

GSTT1 and GSTM1 polymorphisms in Australian chronic obstructive pulmonary disease (COPD) patients

1999

Conference Publication

GSTM1 genotypes in Australian patients with NSCLC

Gan, R., Yang, I., Tunnicliffe, A. M., Rabnott, G. C., Bowman, R., Zimmerman, P.V. and Fong, K. M. (1999). GSTM1 genotypes in Australian patients with NSCLC. Heart and Lungs, Canberra, 26 Feb - 3 March 1999. Carlton, Vic.: Blackwell Science.

GSTM1 genotypes in Australian patients with NSCLC

1999

Journal Article

Trepopnoea due to positional narrowing of the left main bronchus

Yang, I.A., Bell, S.C., Fong, K.M. and Aldons, P.M. (1999). Trepopnoea due to positional narrowing of the left main bronchus. Australian and New Zealand Journal of Medicine, 29 (6), 838-839. doi: 10.1111/j.1445-5994.1999.tb00800.x

Trepopnoea due to positional narrowing of the left main bronchus

1999

Conference Publication

GSTM1 and GSTP1 polymorphisms in chronic obstructive pulmonary disease (COPD)

Yang, I. A., Gan, R., Tunnicliffe, A. M., Rabnott, G. C., Slaughter, R., Zimmerman, P.V. and Fong, K. M. (1999). GSTM1 and GSTP1 polymorphisms in chronic obstructive pulmonary disease (COPD). Pulmonary-Renal Interface, Hyatt Regency Sanctuary Cove, 26 - 28 Nov, 1999. Qld.: Thoracic Society of Qld..

GSTM1 and GSTP1 polymorphisms in chronic obstructive pulmonary disease (COPD)

1999

Conference Publication

Quantification of pulmonary emphysema using high-resolution computed tomography

Yang, I., Slaughter, R., Roszkowski, A., Fong, K. M. and Zimmerman, P. V. (1999). Quantification of pulmonary emphysema using high-resolution computed tomography. Heart and Lungs., Canberra, 26 Feb - 3 March 1999. Carlton, Vic.: Blackwell Science.

Quantification of pulmonary emphysema using high-resolution computed tomography

1999

Conference Publication

Health informatics in nursing education, research and quality assurance for asthma

Moloney, C., Fong, K. M., Yang, I., Reilly, R. and Zimmerman, P. V. (1999). Health informatics in nursing education, research and quality assurance for asthma. Heart and Lungs, Canberra, 26 Feb - 3 March 1999. Carlton, Vic.: Blackwell Science.

Health informatics in nursing education, research and quality assurance for asthma

Current funding

  • 2025 - 2027
    Extracellular-vesicles derived RNA biomarkers of lung cancer in never-smokers for early cancer detection
    Prince Charles Hospital Foundation
    Open grant
  • 2024 - 2026
    Changes in the lung microbiome with use of inhaled steroids in chronic obstructive pulmonary disease (COPD)
    Prince Charles Hospital Foundation
    Open grant
  • 2024 - 2025
    Lung Cancer Screening in Queensland
    Cancer Council Queensland
    Open grant
  • 2023 - 2026
    'Max Up' Trial - Maximising uptake of lung cancer screening and smoking cessation outcomes
    NHMRC MRFF EMCR - Early to Mid-Career Researchers
    Open grant
  • 2023 - 2025
    Transforming the care of people living with chronic obstructive pulmonary disease (COPD) using digital health
    Prince Charles Hospital Foundation
    Open grant
  • 2022 - 2026
    Defining the role and therapeutic manipulation of the gut-lung axis in respiratory disease (NHMRC Synergy administered by University of Technology Sydney)
    University of Technology Sydney
    Open grant
  • 2021 - 2025
    ACRF Lung Cancer Screening CENTRE OF EXCELLENCE (LUSCE)
    Australian Cancer Research Foundation
    Open grant
  • 2021 - 2026
    Lung cancer screening for early detection
    NHMRC MRFF EPCDR - Improving Diagnosis in Cancers with Low Survival Rates
    Open grant
  • 2021 - 2025
    Activating primary care COPD patients with Multi-morbidity (APCOM) study (MRFF Primary Health Care Research Grant led by Bond University)
    Bond University
    Open grant

Past funding

  • 2024 - 2025
    Cassette printer replacement (TPCHF Equipment Grant)
    Prince Charles Hospital Foundation
    Open grant
  • 2021 - 2023
    Inflammatory changes in 'onion skin' tissue layers surrounding the tumour site in lung cancer
    Prince Charles Hospital Foundation
    Open grant
  • 2020 - 2021
    TapeStation 4150
    Prince Charles Hospital Foundation
    Open grant
  • 2019 - 2020
    Inflammatory and DNA damage mechanisms in response to e-cigarette aerosols in COPD/lung cancer primary human bronchial epithelial cells
    Prince Charles Hospital Foundation
    Open grant
  • 2018 - 2020
    Extracellular vesicles as a novel biomarker for chronic obstructive pulmonary disease (COPD)
    Prince Charles Hospital Foundation
    Open grant
  • 2018 - 2024
    Dietary fibre and short chain fatty acids as immune regulators in COPD: a potential novel therapy
    Prince Charles Hospital Foundation
    Open grant
  • 2018 - 2019
    Bringing Modern Genomics to the Management of Lung Cancer in Queensland ( QGHA grant administered by QUT)
    Queensland University of Technology
    Open grant
  • 2017 - 2019
    Clinical trial validation of a blood exosome-prognosticator in lung cancer
    Prince Charles Hospital Foundation
    Open grant
  • 2017 - 2019
    Detection of microbial pathogens using quantitative polymerase chain reaction (qPCR) in patients with acute exacerbations of COPD
    Prince Charles Hospital Foundation
    Open grant
  • 2017 - 2021
    Testing the lung microbiome to predict risk of frequent exacerbations in COPD
    NHMRC Project Grant
    Open grant
  • 2016 - 2023
    ACRF Centre for Lung Cancer Early Detection
    Australian Cancer Research Foundation
    Open grant
  • 2016 - 2019
    Mobile health for COPD
    Prince Charles Hospital Foundation
    Open grant
  • 2016
    Using the lung microbiome to predict response to continuous antibiotics in COPD
    Australian Respiratory Council
    Open grant
  • 2015 - 2017
    SoM Leaders Research Support for Head Northside Clinical School
    Mayne Bequest Fund
    Open grant
  • 2014 - 2017
    The lung microbiome in coexisting COPD and bronchiectasis
    Prince Charles Hospital Foundation
    Open grant
  • 2014 - 2015
    Electronic Snapshot for Outpatient Management of COPD (ESO-COPD)
    Australian Centre for Health Services Innovation
    Open grant
  • 2013 - 2014
    Improving outcomes for patients with lung cancer and malignant mesothelioma
    Cancer Bequest Fund
    Open grant
  • 2013 - 2017
    PhD Scholarship in lung cancer - Funded by the Lung Foundation Australia/Neville Bantoft Bequest, with the UQ Thoracic Research Centre
    PhD Scholarship in Lung Cancer funded by the Lung Foundation Australia/Neville Bantoft Bequest
    Open grant
  • 2012 - 2017
    Clinical Academic Fellowship - Thoracic Physician
    Clinical Academic Fellowships
    Open grant
  • 2012 - 2017
    NHMRC Career Development Fellowship (Level 2): Preventing complications of chronic obstructive pulmonary disease
    NHMRC Career Development Award
    Open grant
  • 2012 - 2013
    Cigarette smoke and age-related epigenetic changes in the lung
    Prince Charles Hospital Foundation
    Open grant
  • 2012 - 2014
    Fundamental study into the role of the organic fraction on the toxicity of combustion generated airborne particles (ARC Discovery Project led by QUT)
    Queensland University of Technology
    Open grant
  • 2011 - 2012
    The Clinical Utility of High Resolution Melt Analysis in Detecting EGFR Mutations in the Serum of NSCLC Patients
    Pfizer Australia Pty Limited
    Open grant
  • 2011
    Tissue Culture Facility for the UQ Thoracic Research Centre
    NHMRC Equipment Grant
    Open grant
  • 2010 - 2011
    Novel microRNAs in pulmonary neoplasia
    Queensland Health
    Open grant
  • 2009 - 2012
    Mayne Bequest Fund Research Support Award: Thoracic Research
    Mayne Bequest Fund
    Open grant
  • 2009 - 2017
    Low dose CT screening for lung cancer
    Queensland Health Smart Health Research Grant
    Open grant
  • 2009 - 2012
    Genome-wide association study of protective alleles in lung cancer and chronic obstructive pulmonary disease
    Cancer Council Queensland
    Open grant
  • 2009 - 2015
    The AMAZES Study: Asthma and Macrolides: the AZithromycin Efficacy and Safety study (NHMRC Project Grant administered by University of Newcastle)
    University of Newcastle
    Open grant
  • 2008 - 2012
    Genomics of environmental stress and lung damage
    Queensland Health Smart Health Research Grant
    Open grant
  • 2007 - 2012
    Respiratory rehabilitation or self management for Chronic Obstructive Pulmonary Disease: what is the best management approach?
    Medical Benefits Fund of Australia Limited
    Open grant
  • 2007 - 2013
    Aberrant promoter methylation in lung cancer and smokers (TPCH)
    Queensland Health Smart Health Research Grant
    Open grant
  • 2007 - 2011
    Preventing progression of COPD
    NHMRC Career Development Award
    Open grant
  • 2006
    Innate Immunity genes in COPD
    Prince Charles Hospital Foundation
    Open grant
  • 2006
    Molecular pathways associated with the severity of COPD
    Prince Charles Hospital Foundation
    Open grant
  • 2006
    Slowing the Progression of Chronic Lung Disease
    Viertel Foundation (Sylvia and Charles Viertel)
    Open grant
  • 2006 - 2009
    The role of innate immunity genes in COPD
    NHMRC Project Grant
    Open grant
  • 2005 - 2006
    Innate immunity genes in asthma and allergy
    Asthma Foundation of Queensland
    Open grant

Availability

Professor Ian Yang is:
Available for supervision

Before you email them, read our advice on how to contact a supervisor.

Available projects

  • Diagnosis and treatment of chronic obstructive pulmonary disease

    Improving approaches to the early diagnosis, monitoring and management of patients with COPD

  • Lung ageing

    Genetics and epigenetics of ageing in the lung

  • The lung's response to air pollution

    Gene-environment interaction in the lung's response to exposure to air pollutants

Supervision history

Current supervision

  • Doctor Philosophy

    Biomarkers of lung cancer

    Principal Advisor

    Other advisors: Professor Kwun Fong

  • Master Philosophy

    Elastin turnover in the lung microenvironment and its significance in Lung Repair and Non-Small Cell Lung Carcinoma (NSCLC)

    Principal Advisor

  • Master Philosophy

    Elastin turnover in the lung microenvironment and its significance in Lung Repair and Non-Small Cell Lung Carcinoma (NSCLC)

    Principal Advisor

    Other advisors: Professor Kwun Fong

  • Master Philosophy

    A multivariable prediction model for osteoporotic fracture and low bone density in a lung cancer screening cohort

    Associate Advisor

    Other advisors: Professor Kwun Fong, Associate Professor Henry Marshall

  • Doctor Philosophy

    Precision medicine in the genomic era: emerging technologies for molecular profiling of lung cancer

    Associate Advisor

    Other advisors: Professor Kwun Fong

  • Doctor Philosophy

    Blood biomarkers for lung cancer screening

    Associate Advisor

    Other advisors: Professor Kwun Fong, Associate Professor Henry Marshall

  • Master Philosophy

    A multivariable prediction model for osteoporotic fracture in a lung cancer screening cohort

    Associate Advisor

    Other advisors: Professor Kwun Fong, Associate Professor Henry Marshall

  • Doctor Philosophy

    Molecular drivers of lung cancer.

    Associate Advisor

  • Doctor Philosophy

    Randomised pragmatic trial of comprehensive tissue sampling enabled by ultrathin bronchoscopic Radial probe EndoBronchial Ultrasound versus CT-guided TransThoracic needle aspiration/biopsy (REBUTT) for evaluation of peripheral pulmonary lesions.

    Associate Advisor

    Other advisors: Professor Kwun Fong

Completed supervision

Enquiries

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