Overview
Availability
- Honorary Professor Peter Molenaar is:
- Available for supervision
Fields of research
Qualifications
- Bachelor of Pharmacy, Victoria University
- Masters (Coursework), Victoria University
- Doctor of Philosophy, University of Melbourne
Works
Search Professor Peter Molenaar’s works on UQ eSpace
2024
Journal Article
The novel adrenergic agonist ATR-127 targets skeletal muscle and brown adipose tissue to tackle diabesity and steatohepatitis
Talamonti, Emanuela, Davegardh, Jelena, Kalinovich, Anastasia, van Beek, Sten M. M., Dehvari, Nodi, Halleskog, Carina, Bokhari, Hamza M., Hutchinson, Dana S., Ham, Seungmin, Humphrys, Laura J., Dijon, Nicola C., Motso, Aikaterini, Sandstrom, Anna, Zacharewicz, Evelyn, Mutule, Ilga, Suna, Edgars, Spura, Jana, Ditrychova, Karolina, Stoddart, Leigh A., Holliday, Nicholas D., Wright, Shane C., Lauschke, Volker M., Nielsen, Soren, Scheele, Camilla, Cheesman, Elizabeth, Hoeks, Joris, Molenaar, Peter, Summers, Roger J., Pelcman, Benjamin ... Bengtsson, Tore (2024). The novel adrenergic agonist ATR-127 targets skeletal muscle and brown adipose tissue to tackle diabesity and steatohepatitis. Molecular Metabolism, 85 101931, 101931. doi: 10.1016/j.molmet.2024.101931
2024
Book Chapter
Roles of β-adrenoceptor subtypes and therapeutics in human cardiovascular disease: heart failure, tachyarrhythmias and other cardiovascular disorders
Wong, Yee Weng, Haqqani, Haris and Molenaar, Peter (2024). Roles of β-adrenoceptor subtypes and therapeutics in human cardiovascular disease: heart failure, tachyarrhythmias and other cardiovascular disorders. Adrenoceptors. (pp. 1-49) edited by Jillian G. Baker, Martin C. Michel and Roger J. Summers. Berlin, Heidelberg: Springer Berlin Heidelberg. doi: 10.1007/164_2024_720
2023
Journal Article
Potential of β2AR for added benefit in treating heart failure through a better understanding of signaling
Walweel, Kafa, Cheesman, Elizabeth and Molenaar, Peter (2023). Potential of β2AR for added benefit in treating heart failure through a better understanding of signaling. Current Opinion in Physiology, 36 100719, 100719. doi: 10.1016/j.cophys.2023.100719
2023
Journal Article
Donor heart ischemic time can be extended to 8 hours using hypothermic machine perfusion in sheep
See Hoe, Louise E., Bassi, Gianluigi Li, Wildi, Karin, Passmore, Margaret R., Bouquet, Mahe, Sato, Kei, Heinsar, Silver, Ainola, Carmen, Bartnikowski, Nicole, Wilson, Emily S., Hyslop, Kieran, Skeggs, Kris, Obonyo, Nchafatso G., Shuker, Tristan, Bradbury, Lucy, Palmieri, Chiara, Pedersen, Sanne-Engkilde, McDonald, Charles, Colombo, Sebastiano M., Wells, Matthew A., Reid, Janice D., O'Neill, Hollier, Livingstone, Samantha, Abbate, Gabriella, Haymet, Andrew, Jung, Jae-Seung, Sato, Noriko, James, Lynnette, He, Ting ... Fraser, John F. (2023). Donor heart ischemic time can be extended to 8 hours using hypothermic machine perfusion in sheep. The Journal of Heart and Lung Transplantation, 42 (8), 1015-1029. doi: 10.1016/j.healun.2023.03.020
2022
Journal Article
Novel micro-computed tomography contrast agents to visualise the human cardiac conduction system and surrounding structures in hearts from normal, aged, and obese individuals: Iodine and graphene oxide – visualising human conduction system in normal, aged, and obese hearts
Aminu, Abimbola J., Chen, Weixuan, Yin, Zeyuan, Kuniewicz, Marcin, Walocha, Jerzy, Perde, Filip, Molenaar, Peter, Iaizzo, Paul A., Dobrzynski, Halina and Atkinson, Andrew J. (2022). Novel micro-computed tomography contrast agents to visualise the human cardiac conduction system and surrounding structures in hearts from normal, aged, and obese individuals: Iodine and graphene oxide – visualising human conduction system in normal, aged, and obese hearts. Translational Research in Anatomy, 27 100175, 1-17. doi: 10.1016/j.tria.2022.100175
2022
Conference Publication
Antiarrhythmic Effects of Phenytoin, a Novel Heart Failure Diastolic Ryanodine Channel Inhibitor, in Human Failing Ventricle
Spratt, M., Dashwood, A., Cheesman, E., Haqqani, H., Wong, Y., Chan, W., Laver, D. and Molenaar, P. (2022). Antiarrhythmic Effects of Phenytoin, a Novel Heart Failure Diastolic Ryanodine Channel Inhibitor, in Human Failing Ventricle. 70th Annual Scientific Meeting of the Cardiac Society of Australia and New Zealand, Gold Coast, QLD Australia, 11-14 August 2022. Chatswood, NSW Australia: Elsevier. doi: 10.1016/j.hlc.2022.06.062
2022
Conference Publication
Post-transplant cardiac contractility and mitochondrial function is preserved following 8 hours hypothermic ex vivo perfusion in sheep
See Hoe, L., Bouquet, M., Hyslop, K., Passmore, M., Wells, M., Sato, K., Wilson, E., Wildi, K., Skeggs, K., Palmeri, C., Reid, J., O'Neill, H., Bartnikowski, N., Jung, J., Ainola, C., Abbate, G., Colombo, S., Obonyo, N., McDonald, C., Shuker, T., Heinsar, S., Haymet, A., Engkilde-Pedersen, S., Peart, J., Molenaar, P., Li Bassi, G., Suen, J., McGiffin, D. and Fraser, J. (2022). Post-transplant cardiac contractility and mitochondrial function is preserved following 8 hours hypothermic ex vivo perfusion in sheep. 70th Annual Scientific Meeting of the Cardiac Society of Australia and New Zealand, Gold Coast, QLD, Australia, 11-14 August 2022. Chatswood, NSW, Australia: Elsevier. doi: 10.1016/j.hlc.2022.06.547
2021
Journal Article
A clinically relevant sheep model of orthotopic heart transplantation 24 h after donor brainstem death
See Hoe, Louise E., Wildi, Karin, Obonyo, Nchafatso G., Bartnikowski, Nicole, McDonald, Charles, Sato, Kei, Heinsar, Silver, Engkilde-Pedersen, Sanne, Diab, Sara, Passmore, Margaret R., Wells, Matthew A., Boon, Ai-Ching, Esguerra, Arlanna, Platts, David G., James, Lynnette, Bouquet, Mahe, Hyslop, Kieran, Shuker, Tristan, Ainola, Carmen, Colombo, Sebastiano M., Wilson, Emily S., Millar, Jonathan E., Malfertheiner, Maximillian V., Reid, Janice D., O’Neill, Hollier, Livingstone, Samantha, Abbate, Gabriella, Sato, Noriko, He, Ting ... Fraser, John F. (2021). A clinically relevant sheep model of orthotopic heart transplantation 24 h after donor brainstem death. Intensive Care Medicine Experimental, 9 (1) 60, 1-24. doi: 10.1186/s40635-021-00425-4
2021
Journal Article
Further insights into the molecular complexity of the human sinus node – The role of ‘novel’ transcription factors and microRNAs
Aminu, Abimbola J., Petkova, Maria, Atkinson, Andrew J., Yanni, Joseph, Morris, Alex D., Simms, Robert T., Chen, Weixuan, Yin, Zeyuan, Kuniewicz, Marcin, Holda, Mateusz K., Kuzmin, Vladislav S., Perde, Filip, Molenaar, Peter and Dobrzynski, Halina (2021). Further insights into the molecular complexity of the human sinus node – The role of ‘novel’ transcription factors and microRNAs. Progress in Biophysics and Molecular Biology, 166, 86-104. doi: 10.1016/j.pbiomolbio.2021.04.008
2021
Journal Article
Compromised right ventricular contractility in an ovine model of heart transplantation following 24 h donor brain stem death
Wells, Matthew A., See Hoe, Louise E., Molenaar, Peter, Pedersen, Sanne, Obonyo, Nchafatso G., McDonald, Charles I., Mo, Weilan, Bouquet, Mahè, Hyslop, Kieran, Passmore, Margaret R., Bartnikowski, Nicole, Suen, Jacky Y., Peart, Jason N., McGiffin, David C., Fraser, John F. and on behalf of the Dead Heart Project (2021). Compromised right ventricular contractility in an ovine model of heart transplantation following 24 h donor brain stem death. Pharmacological Research, 169 105631, 1-12. doi: 10.1016/j.phrs.2021.105631
2021
Journal Article
Effects of omecamtiv mecarbil on failing human ventricular trabeculae and interaction with (−)‐noradrenaline
Dashwood, Alexander, Cheesman, Elizabeth, Wong, Yee Weng, Haqqani, Haris, Beard, Nicole, Hay, Karen, Spratt, Melanie, Chan, Wandy and Molenaar, Peter (2021). Effects of omecamtiv mecarbil on failing human ventricular trabeculae and interaction with (−)‐noradrenaline. Pharmacology Research and Perspectives, 9 (3) e00760, e00760. doi: 10.1002/prp2.760
2021
Journal Article
Conserved Role of the Large Conductance Calcium-Activated Potassium Channel, KCa1.1, in Sinus Node Function and Arrhythmia Risk
Pineda, Santiago, Nikolova-Krstevski, Vesna, Leimena, Christiana, Atkinson, Andrew J., Altekoester, Ann-Kristin, Cox, Charles D., Jacoby, Arie, Huttner, Inken G., Ju, Yue-Kun, Soka, Magdalena, Ohanian, Monique, Trivedi, Gunjan, Kalvakuri, Sreehari, Birker, Katja, Johnson, Renee, Molenaar, Peter, Kuchar, Dennis, Allen, David G., Van Helden, Dirk F., Harvey, Richard P., Hill, Adam P., Bodmer, Rolf, Vogler, Georg, Dobrzynski, Halina, Ocorr, Karen and Fatkin, Diane (2021). Conserved Role of the Large Conductance Calcium-Activated Potassium Channel, KCa1.1, in Sinus Node Function and Arrhythmia Risk. Circulation: Genomic and Precision Medicine, 14 (2) 003144, 230-242. doi: 10.1161/CIRCGEN.120.003144
2020
Journal Article
Correction to “Understanding How Phosphorylation and Redox Modifications Regulate Cardiac Ryanodine Receptor Type 2 Activity to Produce an Arrhythmogenic Phenotype in Advanced Heart Failure”
Dashwood, Alexander, Beard, Nicole, Wong, Yee Weng, Haqqani, Haris, Cheesman, Elizabeth and Molenaar, Peter (2020). Correction to “Understanding How Phosphorylation and Redox Modifications Regulate Cardiac Ryanodine Receptor Type 2 Activity to Produce an Arrhythmogenic Phenotype in Advanced Heart Failure”. ACS Pharmacology and Translational Science, 3 (6), 1422-1422. doi: 10.1021/acsptsci.0c00148
2020
Journal Article
Sarcoplasmic reticulum calcium mishandling: central tenet in heart failure?
Denniss, Amanda L., Dashwood, Alexander M., Molenaar, Peter and Beard, Nicole A. (2020). Sarcoplasmic reticulum calcium mishandling: central tenet in heart failure?. Biophysical Reviews, 12 (4), 865-878. doi: 10.1007/s12551-020-00736-y
2020
Journal Article
Understanding how phosphorylation and redox modifications regulate cardiac ryanodine receptor type 2 activity to produce an arrhythmogenic phenotype in advanced heart failure
Dashwood, Alexander, Cheesman, Elizabeth, Beard, Nicole, Haqqani, Haris, Wong, Yee Weng and Molenaar, Peter (2020). Understanding how phosphorylation and redox modifications regulate cardiac ryanodine receptor type 2 activity to produce an arrhythmogenic phenotype in advanced heart failure. ACS Pharmacology and Translational Science, 3 (4) acsptsci.0c00003, 563-582. doi: 10.1021/acsptsci.0c00003
2020
Journal Article
Phenytoin reduces activity of cardiac ryanodine receptor 2; a potential mechanism for its cardioprotective action
Ashna, A., van Heiden, D. F., dos Remedios, C., Molenaar, P. and Laver, D. R. (2020). Phenytoin reduces activity of cardiac ryanodine receptor 2; a potential mechanism for its cardioprotective action. Molecular Pharmacology, 97 (4), 250-258. doi: 10.1124/mol.119.117721
2019
Journal Article
Calmodulin inhibition of human RyR2 channels requires phosphorylation of RyR2-S2808 or RyR2-S2814
Walweel, Kafa, Gomez-Hurtado, Nieves, Rebbeck, Robyn T., Oo, Ye Wint, Beard, Nicole A., Molenaar, Peter, dos Remedios, Cris, van Helden, Dirk F., Cornea, Razvan L., Knollmann, Björn C. and Laver, Derek R. (2019). Calmodulin inhibition of human RyR2 channels requires phosphorylation of RyR2-S2808 or RyR2-S2814. Journal of Molecular and Cellular Cardiology, 130, 96-106. doi: 10.1016/j.yjmcc.2019.03.018
2018
Conference Publication
Development of an ovine model of heart transplantation following 24-hour brain stem death
See Hoe, L., Engkilde-Pedersen, S., Obonyo, N., Wells, M., Boon, C., Bartnikowski, N., Passmore, M., McDonald, C., Black, D., Molenaar, P., Diab, S., Suen, J., Marasco, S., McGiffin, D. and Fraser, J. (2018). Development of an ovine model of heart transplantation following 24-hour brain stem death. 66th Cardiac Society of Australia and New Zealand Annual Scientific Meeting, the International Society for Heart Research Australasian Section Annual Scientific Meeting and the 12th Annual Australia and New Zealand Endovascular Therapies Meeting, Brisbane, Australia, 2-5 August 2018. Chatswood, NSW, Australia: Elsevier . doi: 10.1016/j.hlc.2018.06.111
2017
Journal Article
The β3-adrenoceptor agonist mirabegron increases human atrial force through β1-adrenoceptors: an indirect mechanism?
Mo, Weilan, Michel, Martin C., Lee, Xiang Wen, Kaumann, Alberto J. and Molenaar, Peter (2017). The β3-adrenoceptor agonist mirabegron increases human atrial force through β1-adrenoceptors: an indirect mechanism?. British Journal of Pharmacology, 174 (16), 2706-2715. doi: 10.1111/bph.13897
2017
Journal Article
Ryanodine receptor modification and regulation by intracellular Ca2+ and Mg2+ in healthy and failing human hearts
Walweel, K., Molenaar, P., Imtiaz, M. S., Denniss, A., dos Remedios, C., van Helden, D. F., Dulhunty, A. F., Laver, D. R. and Beard, N. A. (2017). Ryanodine receptor modification and regulation by intracellular Ca2+ and Mg2+ in healthy and failing human hearts. Journal of Molecular and Cellular Cardiology, 104, 53-62. doi: 10.1016/j.yjmcc.2017.01.016
Funding
Current funding
Supervision
Availability
- Honorary Professor Peter Molenaar is:
- Available for supervision
Before you email them, read our advice on how to contact a supervisor.
Supervision history
Current supervision
-
Doctor Philosophy
Cause and prevention of stress induced arrhythmias in human heart
Principal Advisor
Other advisors: Dr Yee Weng Wong
Completed supervision
-
2008
Master Philosophy
The Genetic Basis of Carvedilol Responsiveness in Human Heart Failure
Principal Advisor
Other advisors: Professor Ian Yang
-
2006
Doctor Philosophy
FACTORS CONTRIBUTING TO THE DEVELOPMENT OF CARDIAC HYPERTROPHY - CALCINEURIN DEPENDENT PATHWAY
Associate Advisor
-
2005
Doctor Philosophy
THE DEVELOPMENT OF A GENE TRANSFER APPROACH FOR THE TREATMENT OF HYPERTENSION.
Associate Advisor
Media
Enquiries
For media enquiries about Honorary Professor Peter Molenaar's areas of expertise, story ideas and help finding experts, contact our Media team: