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Honorary Professor

Peter Molenaar

Email: 
Phone: 
+61 7 3139 4052

Overview

Availability

Honorary Professor Peter Molenaar is:
Available for supervision

Qualifications

  • Bachelor of Pharmacy, Victoria University
  • Masters (Coursework), Victoria University
  • Doctor of Philosophy, University of Melbourne

Works

Search Professor Peter Molenaar’s works on UQ eSpace

102 works between 1997 and 2024

61 - 80 of 102 works

2004

Journal Article

Functional serotonin 5-HT4 receptors in porcine and human ventricular myocardium with increased 5-HT4 mRNA in heart failure

Brattelid, T, Qvigstad, E, Lynham, JA, Molenaar, P, Aass, H, Geiran, O, Skomedal, T, Osnes, JB, Levy, FO and Kaumann, AJ (2004). Functional serotonin 5-HT4 receptors in porcine and human ventricular myocardium with increased 5-HT4 mRNA in heart failure. Naunyn-Schmiedeberg's Arch Pharmacol, 370 (3), 157-166. doi: 10.1007/s00210-004-0963-0

Functional serotonin 5-HT4 receptors in porcine and human ventricular myocardium with increased 5-HT4 mRNA in heart failure

2004

Journal Article

Investigation of signaling pathways that mediate the inotropic effect of urotensin-II in human heart

Russell, FD and Molenaar, P (2004). Investigation of signaling pathways that mediate the inotropic effect of urotensin-II in human heart. Cardiovascular Research, 63 (4), 673-681. doi: 10.1016/j.cardiores.2004.05.009

Investigation of signaling pathways that mediate the inotropic effect of urotensin-II in human heart

2004

Conference Publication

Activation of calcineurin in human failing heart ventricle by endothelin-1, angiotensin II and urotensin

Li, J., Wang, J., Russell, F. D. and Molenaar, P. (2004). Activation of calcineurin in human failing heart ventricle by endothelin-1, angiotensin II and urotensin. 2004 ISHR World Congress Meeting, Brisbane, Qld, Australia, 7-11 Aug, 2004. United Kingdom: Academic Press.

Activation of calcineurin in human failing heart ventricle by endothelin-1, angiotensin II and urotensin

2003

Journal Article

Intrinsic sympathomimetic activity of (-)-pindolol mediated through a (-)-propranolol-resistant site of the beta(1)-adrenoceptor in human atrium and recombinant receptors

Joseph, Shirin S., Lynham, James A., Molenaar, Peter, Grace, Andrew A., Colledge, William H. and Kaumann, Alberto J. (2003). Intrinsic sympathomimetic activity of (-)-pindolol mediated through a (-)-propranolol-resistant site of the beta(1)-adrenoceptor in human atrium and recombinant receptors. Naunyn-Schmiedeberg's Archives of Pharmacology, 368 (6), 496-503. doi: 10.1007/s00210-003-0835-z

Intrinsic sympathomimetic activity of (-)-pindolol mediated through a (-)-propranolol-resistant site of the beta(1)-adrenoceptor in human atrium and recombinant receptors

2003

Conference Publication

Regulatory myosin light chain signaling pathways in urotensin-II-mediated positive inotropic effect in human right atrium

Russell, F. D. and Molenaar, P. (2003). Regulatory myosin light chain signaling pathways in urotensin-II-mediated positive inotropic effect in human right atrium. ASCEPT, Sydney, 30 Nov - 3 Dec, 2003. Australia: Australasian Society of Clinical & Experimental Pharmacologists & Toxicologists.

Regulatory myosin light chain signaling pathways in urotensin-II-mediated positive inotropic effect in human right atrium

2003

Conference Publication

Intrinsic sympathomimetic activity (ISA) of (-)-pindolol mediated through a (-)-propranolol-resistant site of the beta1-adrenoceptor in human right atrium

Molenaar, P. and Kaumann, A. J. (2003). Intrinsic sympathomimetic activity (ISA) of (-)-pindolol mediated through a (-)-propranolol-resistant site of the beta1-adrenoceptor in human right atrium. ASCEPT, Sydney, 30 Nov - 3 Dec, 2003. Australia: Australasian Society of Clinical & Experimental Pharmacologists & Toxicologists.

Intrinsic sympathomimetic activity (ISA) of (-)-pindolol mediated through a (-)-propranolol-resistant site of the beta1-adrenoceptor in human right atrium

2003

Journal Article

(-)-CGP 12177 increases contractile force and hastens relaxation of human myocardial preparations through a propranolol-resistant state of the beta1-adrenoceptor

Sarsero, Doreen, Russell, Fraser D., Lynham, James A., Rabnott, Glenn, Yang, Ian, Fong, Kwun M., Li, Li, Kaumann, Alberto J. and Molenaar, Peter (2003). (-)-CGP 12177 increases contractile force and hastens relaxation of human myocardial preparations through a propranolol-resistant state of the beta1-adrenoceptor. Naunyn-Schmiedeberg's Archives of Pharmacology, 367 (1), 10-21. doi: 10.1007/s00210-002-0652-9

(-)-CGP 12177 increases contractile force and hastens relaxation of human myocardial preparations through a propranolol-resistant state of the beta1-adrenoceptor

2003

Journal Article

Elevated plasma levels of human urotensin-II immunoreactivity in congestive heart failure

Russell, F. D., Meyers, D. E., Galbraith, A., Bett, N., Toth, I., Kearns, P. S. and Molenaar, P. (2003). Elevated plasma levels of human urotensin-II immunoreactivity in congestive heart failure. American Journal of Physiology - Heart & Circulatory Physiology, 285 (Oct.2003), H1576-H1581. doi: 10.1152/ajpheart.00217.2003

Elevated plasma levels of human urotensin-II immunoreactivity in congestive heart failure

2003

Conference Publication

Activation of calcineurin in explanted human ventricle by endogenous peptides

Li, J., Russell, F. D. and Molenaar, P. (2003). Activation of calcineurin in explanted human ventricle by endogenous peptides. ASCEPT, Sydney, 30 Nov - 3 Dec, 2003. Australia: Australasian Society of Clinical & Experimental Pharmacologists & Toxicologists.

Activation of calcineurin in explanted human ventricle by endogenous peptides

2003

Journal Article

The 'state' of beta-adrenoceptors

Molenaar, P. (2003). The 'state' of beta-adrenoceptors. British Journal of Pharmacology, 140 (1), 1-2. doi: 10.1038/sj.bjp.0705420

The 'state' of beta-adrenoceptors

2002

Journal Article

(-)-Pindolol acts through two states of the beta(1)-adrenoceptor in human atrium and CHO cells.

Kaumann, AJ, Lynham, JA, Joseph, SS, Colledge, WH, Grace, AA and Molenaar, P (2002). (-)-Pindolol acts through two states of the beta(1)-adrenoceptor in human atrium and CHO cells.. British Journal of Pharmacology, 135

(-)-Pindolol acts through two states of the beta(1)-adrenoceptor in human atrium and CHO cells.

2002

Journal Article

Conservation of the cardiostimulant effects of (-)-Norepinephrine across Ser49Gly and Gly389Arg Beta1-adrenergic receptor polymorphisms in human right atrium in vitro

Molenaar, P., Rabnott, G., Yang, I., Fong, K. M., Savarimuthu, S. M., Li, L., West, M. J. and Russell, F. D. (2002). Conservation of the cardiostimulant effects of (-)-Norepinephrine across Ser49Gly and Gly389Arg Beta1-adrenergic receptor polymorphisms in human right atrium in vitro. Journal of The American College of Cardiology, 40 (7), 1275-1282. doi: 10.1016/S0735-1097(02)02137-X

Conservation of the cardiostimulant effects of (-)-Norepinephrine across Ser49Gly and Gly389Arg Beta1-adrenergic receptor polymorphisms in human right atrium in vitro

2002

Conference Publication

The positive inotropic effects of norepinephrine are potentiated by chronic beta1-blocker administration but are conserved across Ser49Gly- and Gly389Arg-beta1-adrenergic receptor polymorphisms in human right atrium

Molenaar, P., Russell, F. D., Rabnott, G., Yang, I., Fong, K. M., Savarimuthu, S. M., Li, L. and West, M. J. (2002). The positive inotropic effects of norepinephrine are potentiated by chronic beta1-blocker administration but are conserved across Ser49Gly- and Gly389Arg-beta1-adrenergic receptor polymorphisms in human right atrium. American Heart Association Scientific Sessions 2002, Chicago, 17-20 Nov, 2002. Hagerstown, U.S.A.: Lippincott Williams & Wilkins.

The positive inotropic effects of norepinephrine are potentiated by chronic beta1-blocker administration but are conserved across Ser49Gly- and Gly389Arg-beta1-adrenergic receptor polymorphisms in human right atrium

2001

Journal Article

Cardiostimulant effects of urotensin-II in human heart in vitro

Russell, FD, Molenaar, P and O'Brien, DM (2001). Cardiostimulant effects of urotensin-II in human heart in vitro. British Journal of Pharmacology, 132 (1), 5-9. doi: 10.1038/sj.bjp.0703811

Cardiostimulant effects of urotensin-II in human heart in vitro

2001

Journal Article

Murine ventricular L-type Ca2+ current is enhanced by zinterol via beta(1)-adrenoceptors, and is reduced in TG4 mice overexpressing the human beta(2)-adrenoceptor

Heubach, J. F., Graf, E. M., Molenaar, P., Jager, A., Schroder, F., Herzig, S., Harding, S. E. and Ravens, U. (2001). Murine ventricular L-type Ca2+ current is enhanced by zinterol via beta(1)-adrenoceptors, and is reduced in TG4 mice overexpressing the human beta(2)-adrenoceptor. British Journal of Pharmacology, 133 (1), 73-82. doi: 10.1038/sj.bjp.0704045

Murine ventricular L-type Ca2+ current is enhanced by zinterol via beta(1)-adrenoceptors, and is reduced in TG4 mice overexpressing the human beta(2)-adrenoceptor

2001

Journal Article

Abolition of (-)-CGP 12177-evoked cardiostimulation in double beta(1)/beta(2)-adrenoceptor knockout mice. Obligatory role of beta(1)-adrenoceptors for putative beta 4-adrenoceptor pharmacology

Kaumann, AJ, Engelhardt, S, Hein, L, Molenaar, P and Lohse, M (2001). Abolition of (-)-CGP 12177-evoked cardiostimulation in double beta(1)/beta(2)-adrenoceptor knockout mice. Obligatory role of beta(1)-adrenoceptors for putative beta 4-adrenoceptor pharmacology. Naunyn-schmiedebergs Archives of Pharmacology, 363 (1), 87-93. doi: 10.1007/s002100000336

Abolition of (-)-CGP 12177-evoked cardiostimulation in double beta(1)/beta(2)-adrenoceptor knockout mice. Obligatory role of beta(1)-adrenoceptors for putative beta 4-adrenoceptor pharmacology

2001

Edited Outputs

Proceedings of the Australian Society for Medical Research

P. Molenaar, F. D. Russell, G. C. Rabnott, I. Yang, K. M. Fong and M. J. West eds. (2001). Proceedings of the Australian Society for Medical Research. BioInnovation: The Future of Medical Research, Gold Coast, Queensland, Australia, 24 - 27 November, 2001. Australia: Australian Society for Medical Research.

Proceedings of the Australian Society for Medical Research

2000

Journal Article

Both beta(2)- and beta(1)-adrenergic receptors mediate hastened relaxation and phosphorylation of phospholamban and troponin I in ventricular myocardium of fallot infants, consistent with selective coupling of beta(2)-adrenergic receptors to G(s)-protein

Molenaar, P., Bartel, S., Cochrane, A., Vetter, D., Jalali, H., Pohlner, P., Burrell, K., Karczewski, P, Krause, E. and Kaumann, A. J. (2000). Both beta(2)- and beta(1)-adrenergic receptors mediate hastened relaxation and phosphorylation of phospholamban and troponin I in ventricular myocardium of fallot infants, consistent with selective coupling of beta(2)-adrenergic receptors to G(s)-protein. Circulation, 102 (15), 1814-1821. doi: 10.1161/01.CIR.102.15.1814

Both beta(2)- and beta(1)-adrenergic receptors mediate hastened relaxation and phosphorylation of phospholamban and troponin I in ventricular myocardium of fallot infants, consistent with selective coupling of beta(2)-adrenergic receptors to G(s)-protein

2000

Journal Article

Contribution of beta-adrenoceptor subtypes to relaxation of colon and oesophagus and pacemaker activity of ureter in wild-type and beta(3)-adrenoceptor knockout mice

Oostendorp, J., Preitner, F., Moffatt, J., Jimenez, M., Giacobino, J. P., Molenaar, P. and Kaumann, A. J. (2000). Contribution of beta-adrenoceptor subtypes to relaxation of colon and oesophagus and pacemaker activity of ureter in wild-type and beta(3)-adrenoceptor knockout mice. British Journal of Pharmacology, 130 (4), 747-758. doi: 10.1038/sj.bjp.0703365

Contribution of beta-adrenoceptor subtypes to relaxation of colon and oesophagus and pacemaker activity of ureter in wild-type and beta(3)-adrenoceptor knockout mice

2000

Conference Publication

(-)-CGP 12177-evoked cardiostimulation is abolished in double b1-/b2-adrenoceptor (AR) knockout mice.

Kaumann, A. J., Engelhardt, S., Molenaar, P. and Lohse, M. (2000). (-)-CGP 12177-evoked cardiostimulation is abolished in double b1-/b2-adrenoceptor (AR) knockout mice.. Joint Meeting of ASCEPT and the British Pharmacological Society, Newcastle, Australia, 03-06 Dec, 2000. Sydney: Aust Society of Clin and Exp Pharmacologists and Toxicologists.

(-)-CGP 12177-evoked cardiostimulation is abolished in double b1-/b2-adrenoceptor (AR) knockout mice.

Funding

Current funding

  • 2024 - 2025
    Discovering new therapeutic targets for cardiac fibrosis
    Prince Charles Hospital Foundation
    Open grant
  • 2023 - 2028
    Human Heart Research
    Research Donation Generic
    Open grant
  • 2023 - 2026
    Keeping Failing Hearts Beating - Research Towards the Prevention of Sudden Cardiac Death (Perpetual Impact Philanthropy Grant administered by TPCHF)
    Prince Charles Hospital Foundation
    Open grant

Past funding

  • 2022 - 2023
    Determination of effects of Atrogi compounds in human heart
    Atrogi AB
    Open grant
  • 2021 - 2023
    Anti-arrhythmic medicines: a new prototype targeting the ryanodine channel (RyR2) to reduce sudden death in heart failure patients
    Prince Charles Hospital Foundation
    Open grant
  • 2020 - 2021
    Assessment of effects of Atrogi future medicines in human heart
    Atrogi AB
    Open grant
  • 2020 - 2021
    Development and testing of new medicines in a human model of ventricular arrhythmias to keep heart failure patients alive.
    National Heart Foundation Vanguard Grant
    Open grant
  • 2019 - 2024
    New Medicines to Keep Heart Failure Patients Alive
    Prince Charles Hospital Foundation
    Open grant
  • 2018 - 2023
    Cardio-Vascular Molecular & Translational Research Group
    Prince Charles Hospital Foundation
    Open grant
  • 2016 - 2020
    Identifying cyclic AMP limiting phosphodiesterases for heart failure treatment
    Prince Charles Hospital Foundation
    Open grant
  • 2015 - 2018
    Beta-blocker control of human ventricular arrhythmias in patients with heart failure through phosphodiesterases
    Prince Charles Hospital Foundation
    Open grant
  • 2014 - 2017
    Phosphodiesterase 2, 3 and 4 control of arrhythmias in the human heart
    Prince Charles Hospital Foundation
    Open grant
  • 2013
    Phosphodiesterase enzyme control of arrhythmias in human heart
    Prince Charles Hospital Foundation
    Open grant
  • 2012 - 2014
    Defining role of B2-adrenoceptors and human ventricular arrhythmias
    Prince Charles Hospital Foundation
    Open grant
  • 2011 - 2013
    To determine the effects of (-)- and (±)-ASL-8052 in the human heart (in vitro)
    UniQuest Pty Ltd
    Open grant
  • 2008 - 2010
    Molecular attributes and physiological significance of beta1L-adrenoceptors
    NHMRC Project Grant
    Open grant
  • 2005 - 2006
    The genetic basis of B-blockers in heart failure
    Prince Charles Hospital Foundation
    Open grant
  • 2005 - 2007
    Elucidation of the molecular requirements of the low affinity 'state' of the beta1-adrenoceptor
    NHMRC Project Grant
    Open grant
  • 2004 - 2005
    NHMRC Senior Research Fellowship -- Grant In Aid for Year 7
    NHMRC Fellowship Grant
    Open grant
  • 2003 - 2004
    Adrenergic receptor regulation of calcineurin in the infant human heart
    Prince Charles Hospital Foundation
    Open grant
  • 2002 - 2004
    Contractile and relaxant effects of b2-and b1-adrenoceptors in human heart: blockade by a third generation b-blocker
    NHMRC Project Grant
    Open grant
  • 2000 - 2001
    Polymorphisms of B1 and B2 adrenoceptors in human heart
    National Heart Foundation of Australia
    Open grant
  • 1999 - 2000
    Effects of chronic administration of B-blockers in contractile function in human heart
    Prince Charles Hospital Foundation
    Open grant
  • 1999
    Chronic administration of B-adrenoceptor blockers in end-stage heart failure: Mechanism of benefit
    UQ New Staff Research Start-Up Fund
    Open grant
  • 1999
    Localization and quantitation of novel receptors in human heart
    Ramaciotti Foundation
    Open grant
  • 1998 - 2002
    Modulation of human cardiac function by B-adrenoceptor and endothelin receptor systems
    NHMRC Project Grant - 5 Yr Extended with Fellow
    Open grant
  • 1998 - 2004
    NHMRC RESEARCH FELLOWSHIP (Senior Research Fellow)
    NHMRC Fellowship Grant
    Open grant

Supervision

Availability

Honorary Professor Peter Molenaar is:
Available for supervision

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Supervision history

Current supervision

  • Doctor Philosophy

    Understanding How Phosphorylative and Oxidative Stress Regulate Cardiac Ryanodine Receptor-Type 2 Gating Activity to Produce an Arrhythmogenic Phenotype in Advanced Heart Failure

    Principal Advisor

    Other advisors: Dr Yee Weng Wong

  • Doctor Philosophy

    Cause and prevention of stress induced arrhythmias in human heart

    Principal Advisor

    Other advisors: Dr Yee Weng Wong

Completed supervision

Media

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