Professor Ian Yang
Professor

Ian Yang

Email: 
Phone: 
+61 7 3139 5050

Background

Professor Ian Yang is a Thoracic Physician and Director of Thoracic Medicine at The Prince Charles Hospital, and Head of the PCH-Northside Clinical Unit, School of Clinical Medicine, Faculty of Medicine, The University of Queensland, Brisbane, Australia.

Availability

Professor Ian Yang is:
Available for supervision

Fields of research

Biomedical and Clinical Sciences Cardiovascular medicine and haematology Clinical sciences Oncology and carcinogenesis Respiratory diseases

Qualifications

  • Bachelor (Honours) of Medicine Surgery, The University of Queensland
  • Postgraduate Diploma, University of Newcastle
  • Doctor of Philosophy, The University of Queensland
  • Asian Pacific Society of Respirology, Asian Pacific Society of Respirology
  • Royal Australasian College of Physicians, Royal Australasian College of Physicians
  • The Thoracic Society of Australia and New Zealand, The Thoracic Society of Australia and New Zealand

Research interests

  • Clinical and translational research in chronic lung diseases

    Pathogenesis, diagnosis and treatment of chronic lung diseases, including COPD, asthma, lung cancer, mesothelioma and effects of air pollution

Research impacts

His clinical work is in the field of thoracic medicine, and his research team is studying gene-environmental interaction in COPD, asthma, lung cancer and air pollution. He is involved in the training of higher degree students in translational research into lung diseases.

He is a Chair of the National COPD Guidelines Committee of the Lung Foundation Australia, and a member of the COPD Coordinating Committee. He is Chair of the Medical Programs and Research Advisory Committee of the Asthma Foundation Queensland NSW.

Search Professor Ian Yang’s works on UQ eSpace

360 works between 1999 and 2025
All (360) Journal Article (265) Book Chapter (10) Conference Publication (84) Other Outputs (1)

301 - 320 of 360 works

2009

Journal Article

Deconstructing COPD using genomic tools

Yang, Ian A. and Francis, Santiyagu M. Savarimuthu (2009). Deconstructing COPD using genomic tools. Respirology, 14 (3), 313-317. doi: 10.1111/j.1440-1843.2009.01483.x

Deconstructing COPD using genomic tools

2008

Journal Article

Rationale and design of the PRSM study: pulmonary rehabilitation or self management for chronic obstructive pulmonary disease (COPD), what is the best approach

Chang, Angela T., Haines, Terry, Jackson, Claire, Yang, Ian, Nitz, Jennifer, Low Choy, Nancy and Vicenzino, Bill (2008). Rationale and design of the PRSM study: pulmonary rehabilitation or self management for chronic obstructive pulmonary disease (COPD), what is the best approach. Contemporary Clinical Trials, 29 (5), 796-800. doi: 10.1016/j.cct.2008.04.004

Rationale and design of the PRSM study: pulmonary rehabilitation or self management for chronic obstructive pulmonary disease (COPD), what is the best approach

2008

Journal Article

Genetic susceptibility to the respiratory effects of air pollution

Yang, I. A., Fong, K. M., Zimmerman, P. V., Holgate, S. T. and Holloway, J. W. (2008). Genetic susceptibility to the respiratory effects of air pollution. Thorax, 63 (6), 555-563. doi: 10.1136/thx.2007.079426

Genetic susceptibility to the respiratory effects of air pollution

2008

Journal Article

Systematic review of multidisciplinary teams in the management of lung cancer

Coory, M., Gkolia, P., Yang, I. A., Bowman, R. and Fong, K. (2008). Systematic review of multidisciplinary teams in the management of lung cancer. Lung Cancer, 60 (1), 14-21. doi: 10.1016/j.lungcan.2008.01.008

Systematic review of multidisciplinary teams in the management of lung cancer

2008

Journal Article

Interpatient variability in rates of asthma progression: Can genetics provide an answer?

Holloway, John W., Yang, Ian A. and Holgate, Stephen T. (2008). Interpatient variability in rates of asthma progression: Can genetics provide an answer?. Journal of Allergy and Clinical Immunology, 121 (3), 573-579. doi: 10.1016/j.jaci.2008.01.007

Interpatient variability in rates of asthma progression: Can genetics provide an answer?

2008

Journal Article

Cellular localization of interleukin 13 receptor alpha 2 in human primary bronchial epithelial cells and fibroblasts

Konstantinidis, A. K., Puddicombe, S. M., Mochizuki, A., Sheth, P. D., Yang, Ian Anthony, Yoshisue, H., Wilson, S. J., Davies, D. E., Holgate, S. T. and Holloway, J. W. (2008). Cellular localization of interleukin 13 receptor alpha 2 in human primary bronchial epithelial cells and fibroblasts. Journal of Investigational Allergology and Clinical Immunology, 18 (3), 174-180.

Cellular localization of interleukin 13 receptor alpha 2 in human primary bronchial epithelial cells and fibroblasts

2007

Journal Article

Arg389Gly-beta(1)-adrenergic receptors determine improvement in left ventricular systolic function in nonischemic cardiomyopathy patients with heart failure after chronic treatment with carvedilol

Cheng lu, Meyers, Deborah, Javorsky, George, Bursto, Darryl, Lolekha, Pakorn, Lucas, Margaret, Semmler, Annalese B. T., Savarimuthu, Santiyagu M., Fong, Kwun M., Yang, Ian A., Atherton, John, Galbraith, Andrew J., Parsonage, William A. and Molenaar, Peter (2007). Arg389Gly-beta(1)-adrenergic receptors determine improvement in left ventricular systolic function in nonischemic cardiomyopathy patients with heart failure after chronic treatment with carvedilol. Pharmacogenetics And Genomics, 17 (11), 941-949. doi: 10.1097/FPC.0b013e3282ef7354

Arg389Gly-beta(1)-adrenergic receptors determine improvement in left ventricular systolic function in nonischemic cardiomyopathy patients with heart failure after chronic treatment with carvedilol

2007

Journal Article

Gefitinib for advanced non-small cell lung cancer

Sim, E. H., Yang, I. A., Fong, K., Wood-Baker, R. and Bowman, R. (2007). Gefitinib for advanced non-small cell lung cancer. Cochrane Database of Systematic Reviews, 2018 (4) CD006847. doi: 10.1002/14651858.CD006847

Gefitinib for advanced non-small cell lung cancer

2007

Journal Article

beta(2)-adrenoceptor polymorphisms and obstructive airway diseases: Important issues of study design

Yang, Ian A., Ng, Taria, Molenaar, Peter and Fong, Kwun M. (2007). beta(2)-adrenoceptor polymorphisms and obstructive airway diseases: Important issues of study design. Clinical And Experimental Pharmacology and Physiology, 34 (10), 1029-1036. doi: 10.1111/j.1440-1681.2007.04731.x

beta(2)-adrenoceptor polymorphisms and obstructive airway diseases: Important issues of study design

2007

Journal Article

Asthma: advancing gene-environment studies

Yang, I. A. and Holloway, J. W. (2007). Asthma: advancing gene-environment studies. Clinical and Experimental Allergy, 37 (9), 1264-1266. doi: 10.1111/j.1365-2222.2007.02798.x

Asthma: advancing gene-environment studies

2007

Journal Article

Genetic association studies of interleukin-13 receptor alpha-1 subunit gene polymorphisms in asthma and atopy

Konstantinidis, A. K., Barton, S. J., Sayers. I., Yang, I. A., Lordan, J. L., Rorke, S., Clough, J. B., Holgate, S. T. and Holloway, J. W. (2007). Genetic association studies of interleukin-13 receptor alpha-1 subunit gene polymorphisms in asthma and atopy. The European Respiratory Journal, 30 (1), 40-47. doi: 10.1183/09031936.00025706

Genetic association studies of interleukin-13 receptor alpha-1 subunit gene polymorphisms in asthma and atopy

2007

Journal Article

(-)Adrenaline elicits positive inotropic,lusitropic, and biochemical effects through ß2-adrenoceptors in human atrial myocardium from nonfailing and failing hearts, consisten with Gs coupling but not with Gi coupling.

Molenaar, P., Savarimuthu, S. M., Sarsero, D., Chen, L., Semmler, A. B. T., Carle, A., Yang, I., Bartel, S., Vetter, D., Beyerdorfer, I., Krause,E-G. and Kaumann, A. J. (2007). (-)Adrenaline elicits positive inotropic,lusitropic, and biochemical effects through ß2-adrenoceptors in human atrial myocardium from nonfailing and failing hearts, consisten with Gs coupling but not with Gi coupling.. Naunyn-Schmiedeberg's Archives of Pharmocolgy, 375 (1), 11-28. doi: 10.1007/s00210-007-0138-x

(-)Adrenaline elicits positive inotropic,lusitropic, and biochemical effects through ß2-adrenoceptors in human atrial myocardium from nonfailing and failing hearts, consisten with Gs coupling but not with Gi coupling.

2007

Book Chapter

Perfusion CT applications in lung cancer

Fong, Kwun M., Bowman, Rayleen V., Yang, Ian A. and Miles, Kenneth A. (2007). Perfusion CT applications in lung cancer. Multi-Detector Computed Tomography in Oncology: CT Perfusion Imaging. (pp. 111-128) edited by Kenneth Miles, Chusilip Charnsangavej and Charles A. Cuenod. New York, United States: Informa Healthcare.

Perfusion CT applications in lung cancer

2007

Journal Article

Gene expression of lung squamous cell carcinoma reflects mode of lymph node involvement

Larsen, J.E., Pavey, S.J., Bowman, R., Yang, I.A., Clarke, B.E., Colosimo, M.L., Hayward, N.K. and Fong, K.M. (2007). Gene expression of lung squamous cell carcinoma reflects mode of lymph node involvement. The European Respiratory Journal, 30 (1), 21-25. doi: 10.1183/09031936.00161306

Gene expression of lung squamous cell carcinoma reflects mode of lymph node involvement

2007

Journal Article

Gene-environmental interaction in asthma

Yang, Ian A., Savarimuthu, Santiyagu, Kim, Samuel T., Holloway, John W., Bell, Scott C. and Fong, Kwun M. (2007). Gene-environmental interaction in asthma. Current Opinion in Allergy & Clinical Immunology, 7 (1), 75-82. doi: 10.1097/ACI.0b013e328012ce39

Gene-environmental interaction in asthma

2007

Journal Article

Inhaled corticosteroids for stable chronic obstructive pulmonary disease (Review)

Yang, I. A., Fong, K. M., Sim, E. H. A., Black, P. N. and Lasserson, T. J. (2007). Inhaled corticosteroids for stable chronic obstructive pulmonary disease (Review). Cochrane Database of Systematic Reviews, 2023 (2) CD002991, 1-126. doi: 10.1002/14651858.CD002991.pub2

Inhaled corticosteroids for stable chronic obstructive pulmonary disease (Review)

2006

Journal Article

Epigenetics of lung cancer

Bowman, Rayleen V., Yang, Ian A., Semmler, Annalese B. T. and Fong, Kwun M. (2006). Epigenetics of lung cancer. Respirology, 11 (4), 355-365. doi: 10.1111/j.1440-1843.2006.00859.x

Epigenetics of lung cancer

2006

Journal Article

The role of toll-like receptors and related receptors of the innate immune system in asthma

Yang, Ian A., Fong, Kwun M., Holgate, Stephen T. and Holloway, John W. (2006). The role of toll-like receptors and related receptors of the innate immune system in asthma. Current Opinion In Allergy and Clinical Immunology, 6 (1), 23-28. doi: 10.1097/01.all.0000200503.77295.bb

The role of toll-like receptors and related receptors of the innate immune system in asthma

2006

Conference Publication

Carvedilol causes a greater increase in heart function in idiopathic dilated cardiomyopathy patients with ARG389-compared to GLY389 Beta1-adrenoceptors

Molenaar, P., Chen, Lu, Meyers, E., Javorsky, G., Burstow, M., Lucas, P., Lolekha, J., Atherton, A., Semmler, A. B., Savarimuthu, S., Fong, K. M., Yang, I. A., Galbraith, A. and Parsonage, W. A. (2006). Carvedilol causes a greater increase in heart function in idiopathic dilated cardiomyopathy patients with ARG389-compared to GLY389 Beta1-adrenoceptors. The Australian Health and Medical Research Congress, Melbourn, Australia, 26th November - 1st December, 2006. Australia: Australian Govenment NHMRC.

Carvedilol causes a greater increase in heart function in idiopathic dilated cardiomyopathy patients with ARG389-compared to GLY389 Beta1-adrenoceptors

2006

Journal Article

Association of asthma with a functional promoter polymorphism in the IL16 gene

Burkart, Kristin M., Barton, Sheila J., Holloway, John W., Yang, Ian A., Cakebread, Julie A., Cruikshank, William, Little, Frederic, Jin, Xiaoyi, Farrier, Lindsay A., Clough, Joanne B., Keith, Tim P., Holgate, Stephen, Center, David M. and O'Connor, George T. (2006). Association of asthma with a functional promoter polymorphism in the IL16 gene. Journal of Allergy And Clinical Immunologyhttp://espace.library.uq.edu.au/workflow/edit_metadata.php?id=234360&wfs_id=778, 117 (1), 86-91. doi: 10.1016/j.jaci.2005.10.011

Association of asthma with a functional promoter polymorphism in the IL16 gene

Current funding

  • 2025 - 2027
    Extracellular-vesicles derived RNA biomarkers of lung cancer in never-smokers for early cancer detection
    Prince Charles Hospital Foundation
    Open grant
  • 2024 - 2026
    Changes in the lung microbiome with use of inhaled steroids in chronic obstructive pulmonary disease (COPD)
    Prince Charles Hospital Foundation
    Open grant
  • 2024 - 2025
    Lung Cancer Screening in Queensland
    Cancer Council Queensland
    Open grant
  • 2023 - 2026
    'Max Up' Trial - Maximising uptake of lung cancer screening and smoking cessation outcomes
    NHMRC MRFF EMCR - Early to Mid-Career Researchers
    Open grant
  • 2023 - 2025
    Transforming the care of people living with chronic obstructive pulmonary disease (COPD) using digital health
    Prince Charles Hospital Foundation
    Open grant
  • 2022 - 2026
    Defining the role and therapeutic manipulation of the gut-lung axis in respiratory disease (NHMRC Synergy administered by University of Technology Sydney)
    University of Technology Sydney
    Open grant
  • 2021 - 2025
    ACRF Lung Cancer Screening CENTRE OF EXCELLENCE (LUSCE)
    Australian Cancer Research Foundation
    Open grant
  • 2021 - 2026
    Lung cancer screening for early detection
    NHMRC MRFF EPCDR - Improving Diagnosis in Cancers with Low Survival Rates
    Open grant
  • 2021 - 2025
    Activating primary care COPD patients with Multi-morbidity (APCOM) study (MRFF Primary Health Care Research Grant led by Bond University)
    Bond University
    Open grant

Past funding

  • 2024 - 2025
    Cassette printer replacement (TPCHF Equipment Grant)
    Prince Charles Hospital Foundation
    Open grant
  • 2021 - 2023
    Inflammatory changes in 'onion skin' tissue layers surrounding the tumour site in lung cancer
    Prince Charles Hospital Foundation
    Open grant
  • 2020 - 2021
    TapeStation 4150
    Prince Charles Hospital Foundation
    Open grant
  • 2019 - 2020
    Inflammatory and DNA damage mechanisms in response to e-cigarette aerosols in COPD/lung cancer primary human bronchial epithelial cells
    Prince Charles Hospital Foundation
    Open grant
  • 2018 - 2020
    Extracellular vesicles as a novel biomarker for chronic obstructive pulmonary disease (COPD)
    Prince Charles Hospital Foundation
    Open grant
  • 2018 - 2024
    Dietary fibre and short chain fatty acids as immune regulators in COPD: a potential novel therapy
    Prince Charles Hospital Foundation
    Open grant
  • 2018 - 2019
    Bringing Modern Genomics to the Management of Lung Cancer in Queensland ( QGHA grant administered by QUT)
    Queensland University of Technology
    Open grant
  • 2017 - 2019
    Clinical trial validation of a blood exosome-prognosticator in lung cancer
    Prince Charles Hospital Foundation
    Open grant
  • 2017 - 2019
    Detection of microbial pathogens using quantitative polymerase chain reaction (qPCR) in patients with acute exacerbations of COPD
    Prince Charles Hospital Foundation
    Open grant
  • 2017 - 2021
    Testing the lung microbiome to predict risk of frequent exacerbations in COPD
    NHMRC Project Grant
    Open grant
  • 2016 - 2023
    ACRF Centre for Lung Cancer Early Detection
    Australian Cancer Research Foundation
    Open grant
  • 2016 - 2019
    Mobile health for COPD
    Prince Charles Hospital Foundation
    Open grant
  • 2016
    Using the lung microbiome to predict response to continuous antibiotics in COPD
    Australian Respiratory Council
    Open grant
  • 2015 - 2017
    SoM Leaders Research Support for Head Northside Clinical School
    Mayne Bequest Fund
    Open grant
  • 2014 - 2017
    The lung microbiome in coexisting COPD and bronchiectasis
    Prince Charles Hospital Foundation
    Open grant
  • 2014 - 2015
    Electronic Snapshot for Outpatient Management of COPD (ESO-COPD)
    Australian Centre for Health Services Innovation
    Open grant
  • 2013 - 2014
    Improving outcomes for patients with lung cancer and malignant mesothelioma
    Cancer Bequest Fund
    Open grant
  • 2013 - 2017
    PhD Scholarship in lung cancer - Funded by the Lung Foundation Australia/Neville Bantoft Bequest, with the UQ Thoracic Research Centre
    PhD Scholarship in Lung Cancer funded by the Lung Foundation Australia/Neville Bantoft Bequest
    Open grant
  • 2012 - 2017
    Clinical Academic Fellowship - Thoracic Physician
    Clinical Academic Fellowships
    Open grant
  • 2012 - 2017
    NHMRC Career Development Fellowship (Level 2): Preventing complications of chronic obstructive pulmonary disease
    NHMRC Career Development Award
    Open grant
  • 2012 - 2013
    Cigarette smoke and age-related epigenetic changes in the lung
    Prince Charles Hospital Foundation
    Open grant
  • 2012 - 2014
    Fundamental study into the role of the organic fraction on the toxicity of combustion generated airborne particles (ARC Discovery Project led by QUT)
    Queensland University of Technology
    Open grant
  • 2011 - 2012
    The Clinical Utility of High Resolution Melt Analysis in Detecting EGFR Mutations in the Serum of NSCLC Patients
    Pfizer Australia Pty Limited
    Open grant
  • 2011
    Tissue Culture Facility for the UQ Thoracic Research Centre
    NHMRC Equipment Grant
    Open grant
  • 2010 - 2011
    Novel microRNAs in pulmonary neoplasia
    Queensland Health
    Open grant
  • 2009 - 2012
    Mayne Bequest Fund Research Support Award: Thoracic Research
    Mayne Bequest Fund
    Open grant
  • 2009 - 2017
    Low dose CT screening for lung cancer
    Queensland Health Smart Health Research Grant
    Open grant
  • 2009 - 2012
    Genome-wide association study of protective alleles in lung cancer and chronic obstructive pulmonary disease
    Cancer Council Queensland
    Open grant
  • 2009 - 2015
    The AMAZES Study: Asthma and Macrolides: the AZithromycin Efficacy and Safety study (NHMRC Project Grant administered by University of Newcastle)
    University of Newcastle
    Open grant
  • 2008 - 2012
    Genomics of environmental stress and lung damage
    Queensland Health Smart Health Research Grant
    Open grant
  • 2007 - 2012
    Respiratory rehabilitation or self management for Chronic Obstructive Pulmonary Disease: what is the best management approach?
    Medical Benefits Fund of Australia Limited
    Open grant
  • 2007 - 2013
    Aberrant promoter methylation in lung cancer and smokers (TPCH)
    Queensland Health Smart Health Research Grant
    Open grant
  • 2007 - 2011
    Preventing progression of COPD
    NHMRC Career Development Award
    Open grant
  • 2006
    Innate Immunity genes in COPD
    Prince Charles Hospital Foundation
    Open grant
  • 2006
    Molecular pathways associated with the severity of COPD
    Prince Charles Hospital Foundation
    Open grant
  • 2006
    Slowing the Progression of Chronic Lung Disease
    Viertel Foundation (Sylvia and Charles Viertel)
    Open grant
  • 2006 - 2009
    The role of innate immunity genes in COPD
    NHMRC Project Grant
    Open grant
  • 2005 - 2006
    Innate immunity genes in asthma and allergy
    Asthma Foundation of Queensland
    Open grant

Availability

Professor Ian Yang is:
Available for supervision

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Available projects

  • Diagnosis and treatment of chronic obstructive pulmonary disease

    Improving approaches to the early diagnosis, monitoring and management of patients with COPD

  • Lung ageing

    Genetics and epigenetics of ageing in the lung

  • The lung's response to air pollution

    Gene-environment interaction in the lung's response to exposure to air pollutants

Supervision history

Current supervision

  • Master Philosophy

    Elastin turnover in the lung microenvironment and its significance in Lung Repair and Non-Small Cell Lung Carcinoma (NSCLC)

    Principal Advisor

  • Doctor Philosophy

    Biomarkers of lung cancer

    Principal Advisor

    Other advisors: Professor Kwun Fong

  • Master Philosophy

    Elastin turnover in the lung microenvironment and its significance in Lung Repair and Non-Small Cell Lung Carcinoma (NSCLC)

    Principal Advisor

    Other advisors: Professor Kwun Fong

  • Doctor Philosophy

    Molecular drivers of lung cancer.

    Associate Advisor

  • Doctor Philosophy

    Randomised pragmatic trial of comprehensive tissue sampling enabled by ultrathin bronchoscopic Radial probe EndoBronchial Ultrasound versus CT-guided TransThoracic needle aspiration/biopsy (REBUTT) for evaluation of peripheral pulmonary lesions.

    Associate Advisor

    Other advisors: Professor Kwun Fong

  • Master Philosophy

    A multivariable prediction model for osteoporotic fracture and low bone density in a lung cancer screening cohort

    Associate Advisor

    Other advisors: Professor Kwun Fong, Associate Professor Henry Marshall

  • Doctor Philosophy

    Precision medicine in the genomic era: emerging technologies for molecular profiling of lung cancer

    Associate Advisor

    Other advisors: Professor Kwun Fong

  • Doctor Philosophy

    Blood biomarkers for lung cancer screening

    Associate Advisor

    Other advisors: Professor Kwun Fong, Associate Professor Henry Marshall

  • Master Philosophy

    A multivariable prediction model for osteoporotic fracture in a lung cancer screening cohort

    Associate Advisor

    Other advisors: Professor Kwun Fong, Associate Professor Henry Marshall

Completed supervision

Enquiries

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