Overview
Background
After completing my undergraduate and postgraduate studies at the University of Melbourne, I had a Postdoctoral position at the University of Melbourne from 2011-2013 and held a Victorian Postdoctoral Resarch Fellowship at Kings College London (UK) from 2014-2015 and University of Melbourne in 2016. I took up an Australian Research Council DECRA Fellowship at Monash University from 2017-2019 and was a National Imaging Facility research fellow from 2020-2021. I joined The University of Queensland in 2022 as the Head of Radiochemistry at the Centre for Advanced Imaging.
Availability
- Dr Brett Paterson is:
- Available for supervision
- Media expert
Research impacts
Design and synthesis of radiopharmaceuticals for molecular imaging and targeted radiotherapy. In collaboration with industry, Associate Prof Paterson's research has contributed to the development and translation of new agents for the detection and treatment of cancer.
Works
Search Professor Brett Paterson’s works on UQ eSpace
2024
Journal Article
Rapid and stable complexation of the α-generators bismuth-212 and lead-212 with a tetraazamacrocyclic chelator bearing thiosemicarbazone pendant arms
Grieve, Melyssa L., Davey, Patrick R. W. J., Bernhardt, Paul V., Forsyth, Craig M. and Paterson, Brett M. (2024). Rapid and stable complexation of the α-generators bismuth-212 and lead-212 with a tetraazamacrocyclic chelator bearing thiosemicarbazone pendant arms. Inorganic Chemistry Frontiers, 11 (21), 7307-7323. doi: 10.1039/d4qi01338g
2024
Journal Article
Intranasal delivery of imaging agents to the brain
Almahmoud, Abdallah, Parekh, Harendra S., Paterson, Brett M., Tupally, Karnaker Reddy and Vegh, Viktor (2024). Intranasal delivery of imaging agents to the brain. Theranostics, 14 (13), 5022-5101. doi: 10.7150/thno.98473
2023
Conference Publication
Targeting the aryl hydrocarbon receptor to monitor the kynurenine pathway in glioblastoma multiforme using fluorine-18 PET radiotracers
Lim, Ting Xiang, Migotto, Mary-Anne, Mardon, Karine, Paterson, Brett and Reutens, David (2023). Targeting the aryl hydrocarbon receptor to monitor the kynurenine pathway in glioblastoma multiforme using fluorine-18 PET radiotracers. International Symposium on Radiopharmaceutical Sciences iSRS 2023, Honolulu, HI, United States, 22-26 May 2023. Philadelphia, PA, United States: Elsevier.
2023
Conference Publication
Targeting the aryl hydrocarbon receptor to monitor the kynurenine pathway in glioblastoma multiforme using fluorine-18 PET radiotracers
Lim, Ting Xiang, Migotto, Mary-anne, Mardon, Karine, Paterson, Brett and Reutens, David (2023). Targeting the aryl hydrocarbon receptor to monitor the kynurenine pathway in glioblastoma multiforme using fluorine-18 PET radiotracers. International Symposium on Radiopharmaceutical Sciences iSRS 2023, Honolulu, HI USA, 22-26 May 2023. Philadelphia, PA USA: Elsevier. doi: 10.1016/j.nucmedbio.2023.108619
2023
Journal Article
Technetium nitrido complexes of tetradentate thiosemicarbazones: kit-based radiolabeling, characterization, and in vivo evaluation
Kelderman, Cormac A. A., Maclean, Rachel C., Hungnes, Ingebjørg N., Davey, Patrick R. W. J., Salimova, Ekaterina, de Veer, Michael, Patel, Natasha, Ma, Michelle T. and Paterson, Brett M. (2023). Technetium nitrido complexes of tetradentate thiosemicarbazones: kit-based radiolabeling, characterization, and in vivo evaluation. Inorganic Chemistry, 62 (50), 20791-20805. doi: 10.1021/acs.inorgchem.3c02650
2023
Journal Article
Pre-targeting amyloid-β with antibodies for potential molecular imaging of Alzheimer's disease
Morgan, Katherine A., de Veer, Michael, Miles, Luke A., Kelderman, Cormac A. A., McLean, Catriona A., Masters, Colin L., Barnham, Kevin J., White, Jonathan M., Paterson, Brett M. and Donnelly, Paul S. (2023). Pre-targeting amyloid-β with antibodies for potential molecular imaging of Alzheimer's disease. Chemical Communications, 59 (16), 2243-2246. doi: 10.1039/d2cc06850h
2023
Journal Article
A biodistribution study of the radiolabeled Kv1.3-blocking peptide DOTA-HsTX1[R14A] demonstrates brain uptake in a mouse model of neuroinflammation
Reddiar, Sanjeevini Babu, de Veer, Michael, Paterson, Brett M., Sepehrizadeh, Tara, Wai, Dorothy C. C., Csoti, Agota, Panyi, Gyorgy, Nicolazzo, Joseph A. and Norton, Raymond S. (2023). A biodistribution study of the radiolabeled Kv1.3-blocking peptide DOTA-HsTX1[R14A] demonstrates brain uptake in a mouse model of neuroinflammation. Molecular Pharmaceutics, 20 (1), 255-266. doi: 10.1021/acs.molpharmaceut.2c00614
2023
Journal Article
Modern developments in bifunctional chelator design for gallium radiopharmaceuticals
Davey, Patrick R. W. J. and Paterson, Brett M. (2023). Modern developments in bifunctional chelator design for gallium radiopharmaceuticals. Molecules, 28 (1) 203, 1-36. doi: 10.3390/molecules28010203
2022
Journal Article
A silver(I) coordination polymer with bridging bis(thiosemicarbazone) ligands and unsupported argentophilic interactions
Crouch, Sophie A., Davey, Patrick R. W. J., Forsyth, Craig M., Batten, Stuart R. and Paterson, Brett M. (2022). A silver(I) coordination polymer with bridging bis(thiosemicarbazone) ligands and unsupported argentophilic interactions. Journal of Coordination Chemistry, 75 (11-14), 1691-1701. doi: 10.1080/00958972.2022.2092845
2022
Journal Article
An icosanuclear silver(I) cluster supported by bis(thiosemicarbazonato) ligands
Paterson, Brett M., White, Jonathan M. and Donnelly, Paul S. (2022). An icosanuclear silver(I) cluster supported by bis(thiosemicarbazonato) ligands. Australian Journal of Chemistry, 75 (9), 631-635. doi: 10.1071/CH21335
2022
Journal Article
A general design strategy enabling the synthesis of hydrolysis‐resistant, water‐stable titanium(IV) complexes
Koller, Angus J., Saini, Shefali, Chaple, Ivis F., Joaqui‐Joaqui, M. Andrey, Paterson, Brett M., Ma, Michelle T., Blower, Philip J., Pierre, Valérie C., Robinson, Jerome R., Lapi, Suzanne E. and Boros, Eszter (2022). A general design strategy enabling the synthesis of hydrolysis‐resistant, water‐stable titanium(IV) complexes. Angewandte Chemie, 134 (22). doi: 10.1002/ange.202201211
2022
Journal Article
Crystallographic and computational characterisation of the potential PET tracer 1,4,7-triazacyclononane-1,4,7-tri(methylenephosphonato)gallium(III)
Davey, Patrick R. W. J., Forsyth, Craig M. and Paterson, Brett M. (2022). Crystallographic and computational characterisation of the potential PET tracer 1,4,7-triazacyclononane-1,4,7-tri(methylenephosphonato)gallium(III). ChemistrySelect, 7 (5) e202103698. doi: 10.1002/slct.202103698
2022
Journal Article
The evolving coordination chemistry of radiometals for targeted alpha therapy
Grieve, Melyssa L. and Paterson, Brett M. (2022). The evolving coordination chemistry of radiometals for targeted alpha therapy. Australian Journal of Chemistry, 75 (2), 65-88. doi: 10.1071/CH21184
2022
Journal Article
Hexadentate technetium-99m bis(thiosemicarbazonato) complexes: synthesis, characterisation and biodistribution
Kelderman, Cormac A. A., Davey, Patrick R. W. J., Ma, Michelle T., de Veer, Michael, Salimova, Ekaterina, Donnelly, Paul S. and Paterson, Brett M. (2022). Hexadentate technetium-99m bis(thiosemicarbazonato) complexes: synthesis, characterisation and biodistribution. Dalton Transactions, 51 (37), 14064-14078. doi: 10.1039/d2dt01264b
2021
Journal Article
The synthesis of a bis(Thiosemicarbazone) macrocyclic ligand and the Mn(II), Co(II), Zn(II) and 68Ga(III) complexes
Grieve, Melyssa L., Davey, Patrick R. W. J., Forsyth, Craig M. and Paterson, Brett M. (2021). The synthesis of a bis(Thiosemicarbazone) macrocyclic ligand and the Mn(II), Co(II), Zn(II) and 68Ga(III) complexes. Molecules, 26 (12) 3646. doi: 10.3390/molecules26123646
2020
Journal Article
An octadentate bis(semicarbazone) macrocycle: a potential chelator for lead and bismuth radiopharmaceuticals
Lange, Jaclyn L., Davey, Patrick R. W. J., Ma, Michelle T., White, Jonathan M., Morgenstern, Alfred, Bruchertseifer, Frank, Blower, Philip J. and Paterson, Brett M. (2020). An octadentate bis(semicarbazone) macrocycle: a potential chelator for lead and bismuth radiopharmaceuticals. Dalton Transactions, 49 (42), 14962-14974. doi: 10.1039/d0dt02673e
2019
Journal Article
Modulating targeting of poly(ethylene glycol) particles to tumor cells using bispecific antibodies
Cui, Jiwei, Ju, Yi, Houston, Zachary H., Glass, Joshua J., Fletcher, Nicholas L., Alcantara, Sheilajen, Dai, Qiong, Howard, Christopher B., Mahler, Stephen M., Wheatley, Adam K., De Rose, Robert, Brannon, Paul T., Paterson, Brett M., Donnelly, Paul S., Thurecht, Kristofer J., Caruso, Frank and Kent, Stephen J. (2019). Modulating targeting of poly(ethylene glycol) particles to tumor cells using bispecific antibodies. Advanced Healthcare Materials, 8 (9) 1801607, e1801607. doi: 10.1002/adhm.201801607
2019
Journal Article
Modification of biodistribution and brain uptake of copper bis(thiosemicarbazonato) complexes by the incorporation of amine and polyamine functional groups
Paterson, Brett M., Cullinane, Carleen, Crouch, Peter J., White, Anthony R., Barnham, Kevin J., Roselt, Peter D., Noonan, Wayne, Binns, David, Hicks, Rodney J. and Donnelly, Paul S. (2019). Modification of biodistribution and brain uptake of copper bis(thiosemicarbazonato) complexes by the incorporation of amine and polyamine functional groups. Inorganic Chemistry, 58 (7), 4540-4552. doi: 10.1021/acs.inorgchem.9b00117
2019
Journal Article
Tuning the properties of tris(hydroxypyridinone) ligands: efficient 68 Ga chelators for PET imaging
Imberti, Cinzia, Chen, Yu-Lin, Foley, Calum A., Ma, Michelle T., Paterson, Brett M., Wang, Yifu, Young, Jennifer D., Hider, Robert C. and Blower, Philip J. (2019). Tuning the properties of tris(hydroxypyridinone) ligands: efficient 68 Ga chelators for PET imaging. Dalton Transactions, 48 (13), 4299-4313. doi: 10.1039/c8dt04454f
2018
Journal Article
64Cu-SARTATE PET imaging of patients with neuroendocrine tumors demonstrates high tumor uptake and retention, potentially allowing prospective dosimetry for peptide receptor radionuclide therapy
Hicks, Rodney J., Jackson, Price, Kong, Grace, Ware, Robert E., Hofman, Michael S., Pattison, David A., Akhurst, Timothy A., Drummond, Elizabeth, Roselt, Peter, Callahan, Jason, Price, Roger, Jeffery, Charmaine M., Hong, Emily, Noonan, Wayne, Herschtal, Alan, Hicks, Lauren J., Hedt, Amos, Harris, Matthew, Paterson, Brett M. and Donnelly, Paul S. (2018). 64Cu-SARTATE PET imaging of patients with neuroendocrine tumors demonstrates high tumor uptake and retention, potentially allowing prospective dosimetry for peptide receptor radionuclide therapy. Journal of Nuclear Medicine, 60 (6), 777-785. doi: 10.2967/jnumed.118.217745
Supervision
Availability
- Dr Brett Paterson is:
- Available for supervision
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Supervision history
Current supervision
-
Doctor Philosophy
PET imaging agents for osteosarcoma
Principal Advisor
-
Doctor Philosophy
Gel-based drug delivery monitored via medical imaging
Associate Advisor
Other advisors: Dr Harendra Parekh, Dr Karnaker Reddy Tupally, Dr Viktor Vegh
Completed supervision
-
2024
Doctor Philosophy
Development of PET Radioligands targeting the Aryl Hydrocarbon Receptor in Glioblastoma
Associate Advisor
Media
Enquiries
Contact Dr Brett Paterson directly for media enquiries about:
- Inorganic
- Radioactivity
- Radiopharmaceutical
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