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Dr Brett Paterson
Dr

Brett Paterson

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Overview

Background

After completing my undergraduate and postgraduate studies at the University of Melbourne, I had a Postdoctoral position at the University of Melbourne from 2011-2013 and held a Victorian Postdoctoral Resarch Fellowship at Kings College London (UK) from 2014-2015 and University of Melbourne in 2016. I took up an Australian Research Council DECRA Fellowship at Monash University from 2017-2019 and was a National Imaging Facility research fellow from 2020-2021. I joined The University of Queensland in 2022 as the Head of Radiochemistry at the Centre for Advanced Imaging.

Availability

Dr Brett Paterson is:
Available for supervision
Media expert

Research impacts

Design and synthesis of radiopharmaceuticals for molecular imaging and targeted radiotherapy. In collaboration with industry, Associate Prof Paterson's research has contributed to the development and translation of new agents for the detection and treatment of cancer.

Works

Search Professor Brett Paterson’s works on UQ eSpace

60 works between 2007 and 2024

1 - 20 of 60 works

2024

Journal Article

Rapid and stable complexation of the α-generators bismuth-212 and lead-212 with a tetraazamacrocyclic chelator bearing thiosemicarbazone pendant arms

Grieve, Melyssa L., Davey, Patrick R. W. J., Bernhardt, Paul V., Forsyth, Craig M. and Paterson, Brett M. (2024). Rapid and stable complexation of the α-generators bismuth-212 and lead-212 with a tetraazamacrocyclic chelator bearing thiosemicarbazone pendant arms. Inorganic Chemistry Frontiers, 11 (21), 7307-7323. doi: 10.1039/d4qi01338g

Rapid and stable complexation of the α-generators bismuth-212 and lead-212 with a tetraazamacrocyclic chelator bearing thiosemicarbazone pendant arms

2024

Journal Article

Intranasal delivery of imaging agents to the brain

Almahmoud, Abdallah, Parekh, Harendra S., Paterson, Brett M., Tupally, Karnaker Reddy and Vegh, Viktor (2024). Intranasal delivery of imaging agents to the brain. Theranostics, 14 (13), 5022-5101. doi: 10.7150/thno.98473

Intranasal delivery of imaging agents to the brain

2023

Conference Publication

Targeting the aryl hydrocarbon receptor to monitor the kynurenine pathway in glioblastoma multiforme using fluorine-18 PET radiotracers

Lim, Ting Xiang, Migotto, Mary-Anne, Mardon, Karine, Paterson, Brett and Reutens, David (2023). Targeting the aryl hydrocarbon receptor to monitor the kynurenine pathway in glioblastoma multiforme using fluorine-18 PET radiotracers. International Symposium on Radiopharmaceutical Sciences iSRS 2023, Honolulu, HI, United States, 22-26 May 2023. Philadelphia, PA, United States: Elsevier.

Targeting the aryl hydrocarbon receptor to monitor the kynurenine pathway in glioblastoma multiforme using fluorine-18 PET radiotracers

2023

Conference Publication

Targeting the aryl hydrocarbon receptor to monitor the kynurenine pathway in glioblastoma multiforme using fluorine-18 PET radiotracers

Lim, Ting Xiang, Migotto, Mary-anne, Mardon, Karine, Paterson, Brett and Reutens, David (2023). Targeting the aryl hydrocarbon receptor to monitor the kynurenine pathway in glioblastoma multiforme using fluorine-18 PET radiotracers. International Symposium on Radiopharmaceutical Sciences iSRS 2023, Honolulu, HI USA, 22-26 May 2023. Philadelphia, PA USA: Elsevier. doi: 10.1016/j.nucmedbio.2023.108619

Targeting the aryl hydrocarbon receptor to monitor the kynurenine pathway in glioblastoma multiforme using fluorine-18 PET radiotracers

2023

Journal Article

Technetium nitrido complexes of tetradentate thiosemicarbazones: kit-based radiolabeling, characterization, and in vivo evaluation

Kelderman, Cormac A. A., Maclean, Rachel C., Hungnes, Ingebjørg N., Davey, Patrick R. W. J., Salimova, Ekaterina, de Veer, Michael, Patel, Natasha, Ma, Michelle T. and Paterson, Brett M. (2023). Technetium nitrido complexes of tetradentate thiosemicarbazones: kit-based radiolabeling, characterization, and in vivo evaluation. Inorganic Chemistry, 62 (50), 20791-20805. doi: 10.1021/acs.inorgchem.3c02650

Technetium nitrido complexes of tetradentate thiosemicarbazones: kit-based radiolabeling, characterization, and in vivo evaluation

2023

Journal Article

Pre-targeting amyloid-β with antibodies for potential molecular imaging of Alzheimer's disease

Morgan, Katherine A., de Veer, Michael, Miles, Luke A., Kelderman, Cormac A. A., McLean, Catriona A., Masters, Colin L., Barnham, Kevin J., White, Jonathan M., Paterson, Brett M. and Donnelly, Paul S. (2023). Pre-targeting amyloid-β with antibodies for potential molecular imaging of Alzheimer's disease. Chemical Communications, 59 (16), 2243-2246. doi: 10.1039/d2cc06850h

Pre-targeting amyloid-β with antibodies for potential molecular imaging of Alzheimer's disease

2023

Journal Article

A biodistribution study of the radiolabeled Kv1.3-blocking peptide DOTA-HsTX1[R14A] demonstrates brain uptake in a mouse model of neuroinflammation

Reddiar, Sanjeevini Babu, de Veer, Michael, Paterson, Brett M., Sepehrizadeh, Tara, Wai, Dorothy C. C., Csoti, Agota, Panyi, Gyorgy, Nicolazzo, Joseph A. and Norton, Raymond S. (2023). A biodistribution study of the radiolabeled Kv1.3-blocking peptide DOTA-HsTX1[R14A] demonstrates brain uptake in a mouse model of neuroinflammation. Molecular Pharmaceutics, 20 (1), 255-266. doi: 10.1021/acs.molpharmaceut.2c00614

A biodistribution study of the radiolabeled Kv1.3-blocking peptide DOTA-HsTX1[R14A] demonstrates brain uptake in a mouse model of neuroinflammation

2023

Journal Article

Modern developments in bifunctional chelator design for gallium radiopharmaceuticals

Davey, Patrick R. W. J. and Paterson, Brett M. (2023). Modern developments in bifunctional chelator design for gallium radiopharmaceuticals. Molecules, 28 (1) 203, 1-36. doi: 10.3390/molecules28010203

Modern developments in bifunctional chelator design for gallium radiopharmaceuticals

2022

Journal Article

A silver(I) coordination polymer with bridging bis(thiosemicarbazone) ligands and unsupported argentophilic interactions

Crouch, Sophie A., Davey, Patrick R. W. J., Forsyth, Craig M., Batten, Stuart R. and Paterson, Brett M. (2022). A silver(I) coordination polymer with bridging bis(thiosemicarbazone) ligands and unsupported argentophilic interactions. Journal of Coordination Chemistry, 75 (11-14), 1691-1701. doi: 10.1080/00958972.2022.2092845

A silver(I) coordination polymer with bridging bis(thiosemicarbazone) ligands and unsupported argentophilic interactions

2022

Journal Article

An icosanuclear silver(I) cluster supported by bis(thiosemicarbazonato) ligands

Paterson, Brett M., White, Jonathan M. and Donnelly, Paul S. (2022). An icosanuclear silver(I) cluster supported by bis(thiosemicarbazonato) ligands. Australian Journal of Chemistry, 75 (9), 631-635. doi: 10.1071/CH21335

An icosanuclear silver(I) cluster supported by bis(thiosemicarbazonato) ligands

2022

Journal Article

A general design strategy enabling the synthesis of hydrolysis‐resistant, water‐stable titanium(IV) complexes

Koller, Angus J., Saini, Shefali, Chaple, Ivis F., Joaqui‐Joaqui, M. Andrey, Paterson, Brett M., Ma, Michelle T., Blower, Philip J., Pierre, Valérie C., Robinson, Jerome R., Lapi, Suzanne E. and Boros, Eszter (2022). A general design strategy enabling the synthesis of hydrolysis‐resistant, water‐stable titanium(IV) complexes. Angewandte Chemie, 134 (22). doi: 10.1002/ange.202201211

A general design strategy enabling the synthesis of hydrolysis‐resistant, water‐stable titanium(IV) complexes

2022

Journal Article

Crystallographic and computational characterisation of the potential PET tracer 1,4,7-triazacyclononane-1,4,7-tri(methylenephosphonato)gallium(III)

Davey, Patrick R. W. J., Forsyth, Craig M. and Paterson, Brett M. (2022). Crystallographic and computational characterisation of the potential PET tracer 1,4,7-triazacyclononane-1,4,7-tri(methylenephosphonato)gallium(III). ChemistrySelect, 7 (5) e202103698. doi: 10.1002/slct.202103698

Crystallographic and computational characterisation of the potential PET tracer 1,4,7-triazacyclononane-1,4,7-tri(methylenephosphonato)gallium(III)

2022

Journal Article

The evolving coordination chemistry of radiometals for targeted alpha therapy

Grieve, Melyssa L. and Paterson, Brett M. (2022). The evolving coordination chemistry of radiometals for targeted alpha therapy. Australian Journal of Chemistry, 75 (2), 65-88. doi: 10.1071/CH21184

The evolving coordination chemistry of radiometals for targeted alpha therapy

2022

Journal Article

Hexadentate technetium-99m bis(thiosemicarbazonato) complexes: synthesis, characterisation and biodistribution

Kelderman, Cormac A. A., Davey, Patrick R. W. J., Ma, Michelle T., de Veer, Michael, Salimova, Ekaterina, Donnelly, Paul S. and Paterson, Brett M. (2022). Hexadentate technetium-99m bis(thiosemicarbazonato) complexes: synthesis, characterisation and biodistribution. Dalton Transactions, 51 (37), 14064-14078. doi: 10.1039/d2dt01264b

Hexadentate technetium-99m bis(thiosemicarbazonato) complexes: synthesis, characterisation and biodistribution

2021

Journal Article

The synthesis of a bis(Thiosemicarbazone) macrocyclic ligand and the Mn(II), Co(II), Zn(II) and 68Ga(III) complexes

Grieve, Melyssa L., Davey, Patrick R. W. J., Forsyth, Craig M. and Paterson, Brett M. (2021). The synthesis of a bis(Thiosemicarbazone) macrocyclic ligand and the Mn(II), Co(II), Zn(II) and 68Ga(III) complexes. Molecules, 26 (12) 3646. doi: 10.3390/molecules26123646

The synthesis of a bis(Thiosemicarbazone) macrocyclic ligand and the Mn(II), Co(II), Zn(II) and 68Ga(III) complexes

2020

Journal Article

An octadentate bis(semicarbazone) macrocycle: a potential chelator for lead and bismuth radiopharmaceuticals

Lange, Jaclyn L., Davey, Patrick R. W. J., Ma, Michelle T., White, Jonathan M., Morgenstern, Alfred, Bruchertseifer, Frank, Blower, Philip J. and Paterson, Brett M. (2020). An octadentate bis(semicarbazone) macrocycle: a potential chelator for lead and bismuth radiopharmaceuticals. Dalton Transactions, 49 (42), 14962-14974. doi: 10.1039/d0dt02673e

An octadentate bis(semicarbazone) macrocycle: a potential chelator for lead and bismuth radiopharmaceuticals

2019

Journal Article

Modulating targeting of poly(ethylene glycol) particles to tumor cells using bispecific antibodies

Cui, Jiwei, Ju, Yi, Houston, Zachary H., Glass, Joshua J., Fletcher, Nicholas L., Alcantara, Sheilajen, Dai, Qiong, Howard, Christopher B., Mahler, Stephen M., Wheatley, Adam K., De Rose, Robert, Brannon, Paul T., Paterson, Brett M., Donnelly, Paul S., Thurecht, Kristofer J., Caruso, Frank and Kent, Stephen J. (2019). Modulating targeting of poly(ethylene glycol) particles to tumor cells using bispecific antibodies. Advanced Healthcare Materials, 8 (9) 1801607, e1801607. doi: 10.1002/adhm.201801607

Modulating targeting of poly(ethylene glycol) particles to tumor cells using bispecific antibodies

2019

Journal Article

Modification of biodistribution and brain uptake of copper bis(thiosemicarbazonato) complexes by the incorporation of amine and polyamine functional groups

Paterson, Brett M., Cullinane, Carleen, Crouch, Peter J., White, Anthony R., Barnham, Kevin J., Roselt, Peter D., Noonan, Wayne, Binns, David, Hicks, Rodney J. and Donnelly, Paul S. (2019). Modification of biodistribution and brain uptake of copper bis(thiosemicarbazonato) complexes by the incorporation of amine and polyamine functional groups. Inorganic Chemistry, 58 (7), 4540-4552. doi: 10.1021/acs.inorgchem.9b00117

Modification of biodistribution and brain uptake of copper bis(thiosemicarbazonato) complexes by the incorporation of amine and polyamine functional groups

2019

Journal Article

Tuning the properties of tris(hydroxypyridinone) ligands: efficient 68 Ga chelators for PET imaging

Imberti, Cinzia, Chen, Yu-Lin, Foley, Calum A., Ma, Michelle T., Paterson, Brett M., Wang, Yifu, Young, Jennifer D., Hider, Robert C. and Blower, Philip J. (2019). Tuning the properties of tris(hydroxypyridinone) ligands: efficient 68 Ga chelators for PET imaging. Dalton Transactions, 48 (13), 4299-4313. doi: 10.1039/c8dt04454f

Tuning the properties of tris(hydroxypyridinone) ligands: efficient 68 Ga chelators for PET imaging

2018

Journal Article

64Cu-SARTATE PET imaging of patients with neuroendocrine tumors demonstrates high tumor uptake and retention, potentially allowing prospective dosimetry for peptide receptor radionuclide therapy

Hicks, Rodney J., Jackson, Price, Kong, Grace, Ware, Robert E., Hofman, Michael S., Pattison, David A., Akhurst, Timothy A., Drummond, Elizabeth, Roselt, Peter, Callahan, Jason, Price, Roger, Jeffery, Charmaine M., Hong, Emily, Noonan, Wayne, Herschtal, Alan, Hicks, Lauren J., Hedt, Amos, Harris, Matthew, Paterson, Brett M. and Donnelly, Paul S. (2018). 64Cu-SARTATE PET imaging of patients with neuroendocrine tumors demonstrates high tumor uptake and retention, potentially allowing prospective dosimetry for peptide receptor radionuclide therapy. Journal of Nuclear Medicine, 60 (6), 777-785. doi: 10.2967/jnumed.118.217745

64Cu-SARTATE PET imaging of patients with neuroendocrine tumors demonstrates high tumor uptake and retention, potentially allowing prospective dosimetry for peptide receptor radionuclide therapy

Funding

Current funding

  • 2024 - 2027
    Understanding production and application of alpha emitting radionuclides
    ARC Linkage Projects
    Open grant
  • 2023 - 2028
    ARC Research Hub for Advanced Manufacture of Targeted Radiopharmaceuticals
    ARC Industrial Transformation Research Hubs
    Open grant
  • 2017 - 2024
    ARC Training Centre for Innovation in Biomedical Imaging Technology
    ARC Industrial Transformation Training Centres
    Open grant

Supervision

Availability

Dr Brett Paterson is:
Available for supervision

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Supervision history

Current supervision

Completed supervision

Media

Enquiries

Contact Dr Brett Paterson directly for media enquiries about:

  • Inorganic
  • Radioactivity
  • Radiopharmaceutical

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