
Overview
Background
I am a computational biologist with a centre-wide research role in the ARC Centre of Excellence for Plant Success in Nature and Agriculture, based here at UQ. I spend my time researching new computational techniques for predicting complex quantitative traits by integrating multiple layers of 'omics data (amongst dozens of other things!).
Areas of interest:
- Machine Learning, AI and high performance computing to learn and exploit functional connectivity in biological data
- Gene Expressions networks
- Multiplex networks, information propagation and perturbation
- Genomic Prediction
My goal is to aid crop and forestry breeders in selecting parental lines more accurately, which gives us a pathway to improving certain plant species. I also spend time developing new data analysis techniques that are being applied to human disease and conditions such as Autism and substance addiction.
David completed his PhD at Australian National University in 2017, focusing on the genome-wide basis of foliar terpene variation in Eucalyptus. He then undertook a postdoc at Oak Ridge National Laboratory, a US Dept of Energy lab with a focus on big data. After a stint as a staff scientist at Oak Ridge, David arrived at the Centre of Excellence in 2023 in the role of a Senior Research Fellow.
Availability
- Dr David Kainer is:
- Available for supervision
- Media expert
Fields of research
Qualifications
- Doctoral (Research) of Population, Ecological and Evolutionary Genetics, Australian National University
- Member, Australian Bioinformatics and Computational Biology Society, Australian Bioinformatics and Computational Biology Society
- Journal Editorial Board Member, Forestry Research, Forestry Research
- Board Member, IUFRO Tree Biotech, IUFRO Tree Biotech
Research interests
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Graph Neural Networks applied to biological data
Biological interaction data is often best formatted as networks. These can get large and complex, with multiple types of node entities (genes, metabolites etc) and edge relationships. Graph Neural Networks (GNNs) are currently the most powerful way to make predictions on such networks and gain insights that would be hidden from traditional linear models.
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Network perturbation and phenotype prediction
What is the effect of editing a gene, or multiple genes? I am applying AI on biological networks to predict the outcomes of gene knockouts or expression tweaks.
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Tree genomics
All aspects of tree multi-omics, especially genomics. I have worked with data from diverse tree species: Eucalypts, Poplars, Oak as well as tree crops such as Mango.
Works
Search Professor David Kainer’s works on UQ eSpace
2014
Journal Article
Selecting optimal partitioning schemes for phylogenomic datasets
Lanfear, Robert, Calcott, Brett, Kainer, David, Mayer, Christoph and Stamatakis, Alexandros (2014). Selecting optimal partitioning schemes for phylogenomic datasets. BMC Evolutionary Biology, 14 (1) 82, 1-14. doi: 10.1186/1471-2148-14-82
Supervision
Availability
- Dr David Kainer is:
- Available for supervision
Before you email them, read our advice on how to contact a supervisor.
Media
Enquiries
Contact Dr David Kainer directly for media enquiries about:
- biofuel
- bioinformatics
- computational biology
- genomics
- GWAS
- network biology
- Tree Genetics
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