Overview
Background
Maher Gandhi received his medical degree in the UK in 1989, and then trained as a haematologist, including a Fellowship in malignant haematology at Princess Margaret Cancer Centre, Toronto. He was awarded a PhD in immunology at Cambridge University under Patrick Sissons. In 2003 he moved to Brisbane, and works as a Senior Staff Specialist (Pre-Eminent Status) in the Haematology / Oncology Department of the Princess Alexandra Hospital. He leads his own laboratory group and has established an international reputation studying immunity and identification of novel biomarkers in lymphoma, with continuous NHMRC funding since 2005. He was Chair of Laboratory Sciences for the Australasian Leukaemia and Lymphoma Group between 2010-2016, won the prestigious Australian Society of Medical Research Clinical Research Award in 2010 and in 2012 took up the inaugural John McCaffrey Cancer Council of Queensland / Office of Health and Medical Research Clinical Research Fellowship. Between 2011-2014 he was privileged to serve as Chair of the Metro South Human Research Ethics Committee. In 2013 he was appointed Professor of Experimental Haematology, University of Queensland, based at the Translational Research Institute, in 2014 became the inaugural Leukaemia Foundation Chair of Blood Cancer Research at the University of Queensland Diamantina Institute, and was appointed Diamantina Cancer Program Head in 2016. In 2018 to current, he moved to Mater Research, where he is Executive Director, as well Director of MRI-UQ.
Availability
- Professor Maher Gandhi is:
- Available for supervision
- Media expert
Fields of research
Qualifications
- Bachelor of Medicine Surgery, University of Aberdeen
- Doctor of Philosophy, University of Cambridge
Research interests
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Lymphoma
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Immunotherapy
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Biomarkers
Research impacts
The research of the Blood Cancer Research Laboratory aims to understand the basis of lymphoma; to devise new treatments which are less toxic and more effective; to establish new biomarkers which will help determine the most effective treatment strategies and to monitor response and relapse and understand the development of lymphomas. The group has a strong emphasis on patient material, which it obtains from international and national clinical collaborators. Lymphomas studied include Hodgkin Lymphoma, PTLD, Diffuse Large B-cell Lymphoma, Follicular Lymphoma and virus associated lymphomas. We utilise a broad range of approaches including genomics, molecular and cellular biology techniques and functional immunoassays. Several of our studies are linked with the Australasian Leukaemia and Lymphoma Group.
The Mater Foundation, the Leukaemia Foundation, and the Brisbane Girls Grammar School Kirsten Jack Memorial Fund are thanked for their kind support.
Works
Search Professor Maher Gandhi’s works on UQ eSpace
2010
Journal Article
Fulminant infectious mononucleosis and recurrent epstein-barr virus reactivation in an adolescent
Nourse, Jamie P., Jones, Kimberley, Dua, Ujjwal, Runnegar, Naomi, Looke, David, Schmidt, Chris, Tey, Siok-Keen, Kennedy, Glen and Gandhi, Maher K. (2010). Fulminant infectious mononucleosis and recurrent epstein-barr virus reactivation in an adolescent. Clinical Infectious Diseases, 50 (6), e34-e37. doi: 10.1086/650007
2010
Journal Article
Sodium valproate in combination with ganciclovir induces lysis of EBV-infected lymphoma cells without impairing EBV-specific T-cell immunity
Jones, K., Nourse, J., Corbett, G. and Gandhi, M. K. (2010). Sodium valproate in combination with ganciclovir induces lysis of EBV-infected lymphoma cells without impairing EBV-specific T-cell immunity. International Journal of Laboratory Hematology, 32 (1p1), e169-e174. doi: 10.1111/j.1751-553X.2008.01130.x
2010
Conference Publication
Ebv-Positive Dlbcl of the Elderly Is a Distinct Clinico-Biological Entity with Poor Outcome in Chop-R Treated Patients
Gandhi, M., Keane, C., Nourse, J., Jones, K., Ross, N., Han, E. and Nguyen-Van, D. (2010). Ebv-Positive Dlbcl of the Elderly Is a Distinct Clinico-Biological Entity with Poor Outcome in Chop-R Treated Patients. 15th Annual Meeting of the European-Hematology-Association, Barcelona Spain, June 10-13, 2010. Pavia, Italy: Fondazione Ferrata Storti.
2009
Conference Publication
EBV MicroRNA Expression in Virus Driven B-Cell Differentiation and Lymphomagenesis
Nourse, Jamie P., Crooks, Pauline, Van, Do Nguyen, Jones, Kimberley, Ross, Nathan and Gandhi, Maher K. (2009). EBV MicroRNA Expression in Virus Driven B-Cell Differentiation and Lymphomagenesis. 51st Annual Meeting of the American-Society-of-Hematology, New Orleans La, Dec 05-08, 2009. WASHINGTON: AMER SOC HEMATOLOGY.
2009
Conference Publication
Epstein-Barr Virus-specific T Cells as Therapy for Relapsed/Refractory EBV-positive Lymphomas
Jones, Kimberley, Vari, Frank, Khanna, Rajiv, Han, Erica, Singh, Sanjleena, Ritchie, David and Gandhi, Maher K. (2009). Epstein-Barr Virus-specific T Cells as Therapy for Relapsed/Refractory EBV-positive Lymphomas. 24th Annual Meeting of the International-Society-for-Biology-Therapy-of-Cancer, Washington Dc, Oct 29-31, 2009. PHILADELPHIA: LIPPINCOTT WILLIAMS & WILKINS.
2009
Conference Publication
Mechanisms Underlying the Selective Impairment of Epstein Barr Virus-Nuclear Antigen I-specific Effector T Cells Observed in PTLD
Jones, Kimberley, Nouise, J., Morrison, L., Vari, Frank, Moss, D. and Gandhi, Mahei K. (2009). Mechanisms Underlying the Selective Impairment of Epstein Barr Virus-Nuclear Antigen I-specific Effector T Cells Observed in PTLD. 24th Annual Meeting of the International-Society-for-Biology-Therapy-of-Cancer, Washington Dc, Oct 29-31, 2009. PHILADELPHIA: LIPPINCOTT WILLIAMS & WILKINS.
2009
Conference Publication
Cell-free Epstein-Barr Virus DNA is a Specific Biomarker for Tumor Burden in EBV-associated Lymphomas
Jones, Kimberley, Nourse, J., Crooks, P., Gottlieb, D. and Gandhi, Mahei (2009). Cell-free Epstein-Barr Virus DNA is a Specific Biomarker for Tumor Burden in EBV-associated Lymphomas. 24th Annual Meeting of the International-Society-for-Biology-Therapy-of-Cancer, Washington Dc, Oct 29-31, 2009. PHILADELPHIA: LIPPINCOTT WILLIAMS & WILKINS.
2009
Journal Article
Selective accumulation of virus-specific CD8(+) T cells within the peripheral blood stem cell compartment
Singh, Sanjleena, van Hauten, Paulien, Jones, Kimberley, Grimmett, Karen, Mills, Anthony K. and Gandhi, Maher K. (2009). Selective accumulation of virus-specific CD8(+) T cells within the peripheral blood stem cell compartment. Blood, 114 (9), 2001-2003. doi: 10.1182/blood-2009-05-221267
2009
Conference Publication
Ebv Microrna Expression in An In-Vitro Model of B-Cell Differentiation and Lymphomagenesis
Nourse, P., Jones, K., Crooks, P. and Gandhi, M. K. (2009). Ebv Microrna Expression in An In-Vitro Model of B-Cell Differentiation and Lymphomagenesis. 14th Annual Meeting of the European-Hematology-Association, Berlin Germany, Jun 04-07, 2009. WASHINGTON: AMER SOC HEMATOLOGY.
2009
Journal Article
Epstein-Barr virus DNA as a biomarker for Epstein-Barr virus-positive lymphomas: Are we there yet?
Jones, Kimberley and Gandhi, Maher K. (2009). Epstein-Barr virus DNA as a biomarker for Epstein-Barr virus-positive lymphomas: Are we there yet?. Leukemia and Lymphoma, 50 (5), 684-686. doi: 10.1080/10428190902847716
2009
Journal Article
High levels of BACH2 associated with lower levels of BCL2 transcript abundance in t(14;18)(q21;q34) translocation positive non-Hodgkin's lymphoma
Green, Michael, Gandhi, Maher K, Camilleri, Emily, Marlton, Paula, Lea, Rod and Griffiths, Lyn (2009). High levels of BACH2 associated with lower levels of BCL2 transcript abundance in t(14;18)(q21;q34) translocation positive non-Hodgkin's lymphoma. Leukemia Research, 33 (5), 731-734. doi: 10.1016/j.leukres.2008.09.007
2009
Journal Article
What changes are needed to the current direction and interpretation of clinical cancer research to meet the needs of the 21st century?
Gandhi, Maher K. (2009). What changes are needed to the current direction and interpretation of clinical cancer research to meet the needs of the 21st century?. Medical Journal of Australia, 190 (8), 461-461.
2009
Journal Article
The role of Epstein-Barr virus in Richter syndrome
Nourse, Jamie, Jones, Kimberley and Gandhi, Maher K. (2009). The role of Epstein-Barr virus in Richter syndrome. British Journal of Haematology, 144 (4), 613-613. doi: 10.1111/j.1365-2141.2008.07471.x
2009
Book Chapter
Genetic susceptibility to complex traits: moving towards informed analysis of whole-genome screens
Green, Michael R., Camilleri, Emily, Gandhi, Maher K. and Griffiths, Lyn R. (2009). Genetic susceptibility to complex traits: moving towards informed analysis of whole-genome screens. Human genome: features, variations and genetic disorders. (pp. 167-180) edited by Akio Matsumoto and Mai Nakano. New York, NY, United States: Nova Science.
2009
Journal Article
Relative abundance of full-length and truncated FOXP1 isoforms is associated with differential NF kappa B activity in Follicular Lymphoma
Green, Michael R., Gandhi, Maher K., Courtney, Mark J., Marlton, Paula and Griffiths, Lyn (2009). Relative abundance of full-length and truncated FOXP1 isoforms is associated with differential NF kappa B activity in Follicular Lymphoma. Leukemia Research, 33 (12), 1699-1702. doi: 10.1016/j.leukres.2009.05.004
2008
Journal Article
Immunodeficiency-associated lymphomas
Tran, Huy, Nourse, Jamie, Hall, Sara, Green, Michael, Griffiths, Lyn and Gandhi, Maher K. (2008). Immunodeficiency-associated lymphomas. Blood Reviews, 22 (5), 261-281. doi: 10.1016/j.blre.2008.03.009
2008
Journal Article
A new prognosticator for post-transplant lymphoproliferative disorders after renal transplantation
Hourigan, Matthew J., Doecke, James, Mollee, Peter N., Gill, Devinder S., Norris, Debra, Johnson, David W. and Gandhi, Maher K. (2008). A new prognosticator for post-transplant lymphoproliferative disorders after renal transplantation. British Journal of Haematology, 141 (6), 904-907. doi: 10.1111/j.1365-2141.2008.07149.x
2008
Journal Article
Methotrexate-associated mantle-cell lymphoma in an elderly man with myasthenia gravis
Tran, Huy, Cheung, Catherine, Gill, Devinder, Dua, Ujjwal, Nourse, Jamie, Boyle, Richard and Gandhi, Maher K. (2008). Methotrexate-associated mantle-cell lymphoma in an elderly man with myasthenia gravis. Nature Clinical Practice Oncology, 5 (4), 234-238. doi: 10.1038/ncponc1071
2007
Journal Article
Immunity, homing and efficacy of allogeneic adoptive immunotherapy for posttransplant lymphoproliferative disorders
Gandhi, M., Wilkie, G. M., Dua, U., Mollee, P., Grimmett, K., Williams, T., Whitaker, N., Gill, D. and Crawford, D. (2007). Immunity, homing and efficacy of allogeneic adoptive immunotherapy for posttransplant lymphoproliferative disorders. American Journal of Transplantation, 7 (5), 1293-1299. doi: 10.1111/j.1600-6143.2007.01796.x
2007
Journal Article
Epstein-Barr virus T-cell immunity despite rituximab
Nehring, Angela K., Dua, Ujjwal, Mollee, Peter, Gill, Devinder, Grimmett, Karen, Khanna, Rajiv, Moss, Denis and Gandhi, Maher K. (2007). Epstein-Barr virus T-cell immunity despite rituximab. British Journal of Haematology, 136 (4), 628-632. doi: 10.1111/j.1365-2141.2006.06482.x
Funding
Supervision
Availability
- Professor Maher Gandhi is:
- Available for supervision
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Supervision history
Current supervision
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Doctor Philosophy
Impact of genetics upon the tumour microenvironment in Follicular Lymphoma
Principal Advisor
Other advisors: Dr Joshua Tobin, Dr Soi Law, Associate Professor Colm Keane
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Doctor Philosophy
Personalised therapy for lymphoma
Principal Advisor
Other advisors: Honorary Professor Kristen Radford
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Doctor Philosophy
Metabolic Reprogramming of Malignant B-cells Impairs Immune-Fitness of Intratumoral T-Cells in Follicular Lymphoma
Principal Advisor
Other advisors: Dr Joshua Tobin, Dr Soi Law
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Doctor Philosophy
Development of novel vaccines for cancer immunotherapy
Associate Advisor
Other advisors: Dr Kelvin Tuong, Honorary Professor Kristen Radford
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Doctor Philosophy
Investigations in the development of cord blood derived, GMP grade cellular immunotherapies
Associate Advisor
Other advisors: Honorary Professor Kristen Radford
Completed supervision
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2022
Doctor Philosophy
A Comprehensive Study of Intratumoural T-cells in Follicular Lymphoma
Principal Advisor
Other advisors: Dr Soi Law, Associate Professor Colm Keane
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2021
Doctor Philosophy
Clinical and Prognostic Tools to Improve Frontline Management Strategies in Follicular Lymphoma
Principal Advisor
Other advisors: Associate Professor Colm Keane
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2020
Doctor Philosophy
The impact of deficient antigen presentation on the tumour microenvironment of diffuse large B cell lymphoma
Principal Advisor
Other advisors: Associate Professor Colm Keane
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2019
Doctor Philosophy
A LABORATORY STUDY OF PRIMARY CENTRAL NERVOUS SYSTEM LYMPHOMA
Principal Advisor
Other advisors: Associate Professor Colm Keane
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2016
Master Philosophy
Killer cell Immunoglobulin-like Receptors in Immune Thrombocytopenia (ITP)
Principal Advisor
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2013
Doctor Philosophy
Novel strategies for monitoring, treating and preventing Epstein Barr virus-associated Lymphomas
Principal Advisor
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2020
Doctor Philosophy
Characterising miRNA - gene network associated with natural killer cell activation
Associate Advisor
Other advisors: Dr Soi Law
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2019
Doctor Philosophy
Deciphering the structure and function of class I cytokine receptors: GHR and GP130
Associate Advisor
Other advisors: Associate Professor Andrew Brooks
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2013
Doctor Philosophy
IRE1-mediated splicing of xbp1 in Natural Killer cells
Associate Advisor
Media
Enquiries
Contact Professor Maher Gandhi directly for media enquiries about:
- Biomarkers
- Immunotherapy
- Lymphoma
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