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Professor Maher Gandhi
Professor

Maher Gandhi

Email: 

Overview

Background

Maher Gandhi received his medical degree in the UK in 1989, and then trained as a haematologist, including a Fellowship in malignant haematology at Princess Margaret Cancer Centre, Toronto. He was awarded a PhD in immunology at Cambridge University under Patrick Sissons. He moved to Brisbane and from 2003-2024 worked as a Senior Staff Specialist (Pre-Eminent Status) in the Haematology / Oncology Department of the Princess Alexandra Hospital. He leads his own laboratory group and has established an international reputation studying the tumour immune microenvironment in lymphoma and its manipulation, with continuous NHMRC/MRFF funding since 2005. He was Chair of Laboratory Sciences for the Australasian Leukaemia and Lymphoma Group between 2010-2016, won the prestigious Australian Society of Medical Research Clinical Research Award in 2010 and in 2012 took up the inaugural John McCaffrey Cancer Council of Queensland / Office of Health and Medical Research Clinical Research Fellowship. Between 2011-2014 he was privileged to serve as Chair of the Metro South Human Research Ethics Committee. In 2013 he was appointed Professor of Experimental Haematology, University of Queensland, based at the Translational Research Institute, in 2014 became the inaugural Leukaemia Foundation Chair of Blood Cancer Research at the University of Queensland Frazer Institute, and was appointed Cancer Program Head in 2016. In 2018 he became Executive Director and Director of Clinical Research at Mater Research. He also continues to head the Blood Cancer Research Group, which is based in Mater Research. In 2025 to current, he was appointed Chief Executive Officer of the Translational Research Institute and its manufacturing branch TM@TRI, to serve Queenslanders by transforming health through collaborative research.

Availability

Professor Maher Gandhi is:
Available for supervision
Media expert

Qualifications

  • Bachelor of Medicine Surgery, University of Aberdeen
  • Doctor of Philosophy, University of Cambridge

Research interests

  • Lymphoma

  • Immunotherapy

  • Biomarkers

Research impacts

The research of the Blood Cancer Research Laboratory aims to understand the basis of lymphoma; to devise new treatments which are less toxic and more effective; to establish new biomarkers which will help determine the most effective treatment strategies and to monitor response and relapse and understand the development of lymphomas. The group has a strong emphasis on patient material, which it obtains from international and national clinical collaborators. Lymphomas studied includeEBV-associated lymphomas, Hodgkin Lymphoma, PTLD, Diffuse Large B-cell Lymphoma, Follicular Lymphoma and amyloidosis. We utilise a broad range of approaches including genomics, transcriptomics and functional immunoassays, and are conducting a number of MRFF funded cellular therapy studies sponsored by the Australasian Leukaemia and Lymphoma Group.

The Mater Foundation, the Leukaemia Foundation, the Mark Coghlan EBV Lymphoma Project and the Brisbane Girls Grammar School Kirsten Jack Memorial Fund are thanked for their kind support.

Works

Search Professor Maher Gandhi’s works on UQ eSpace

234 works between 1993 and 2025

121 - 140 of 234 works

2014

Journal Article

A multi-centre, single-arm, open-label study evaluating the safety and efficacy of fixed dose rituximab in patients with refractory, relapsed or chronic idiopathic thrombocytopenic purpura (R-ITP1000 study)

Tran, Huyen, Brighton, Tim, Grigg, Andrew, McRae, Simon, Dixon, Joanna, Thurley, Daniel, Gandhi, Maher K., Truman, Matt, Marlton, Paula and Catalano, John (2014). A multi-centre, single-arm, open-label study evaluating the safety and efficacy of fixed dose rituximab in patients with refractory, relapsed or chronic idiopathic thrombocytopenic purpura (R-ITP1000 study). British Journal of Haematology, 167 (2), 243-251. doi: 10.1111/bjh.13029

A multi-centre, single-arm, open-label study evaluating the safety and efficacy of fixed dose rituximab in patients with refractory, relapsed or chronic idiopathic thrombocytopenic purpura (R-ITP1000 study)

2014

Journal Article

In silico analyses reveal common cellular pathways affected by loss of heterozygosity (LOH) events in the lymphomagenesis of Non-Hodgkin’s lymphoma (NHL)

Aya-Bonilla, Carlos, Camilleri, Emily, Haupt, Larisa M., Lea, Rod, Gandhi, Maher K. and Griffiths, Lyn R. (2014). In silico analyses reveal common cellular pathways affected by loss of heterozygosity (LOH) events in the lymphomagenesis of Non-Hodgkin’s lymphoma (NHL). BMC Genomics, 15 (390) 390, 1-12. doi: 10.1186/1471-2164-15-390

In silico analyses reveal common cellular pathways affected by loss of heterozygosity (LOH) events in the lymphomagenesis of Non-Hodgkin’s lymphoma (NHL)

2014

Journal Article

The presence of KIR2DS5 confers protection against adult immune thrombocytopenia

Seymour, L. A., Nourse, J. P., Crooks, P., Wockner, L., Bird, R., Tran, H. and Gandhi, M. K. (2014). The presence of KIR2DS5 confers protection against adult immune thrombocytopenia. Tissue Antigens, 83 (3), 154-160. doi: 10.1111/tan.12295

The presence of KIR2DS5 confers protection against adult immune thrombocytopenia

2014

Journal Article

FCY-receptor IIIA polymorphism p.158F has no negative predictive impact on rituximab therapy with and without sequential chemotherapy in CD20-positive post-transplant lymphoproliferative disorder

Zimmermann, Heiner, Weiland, Theresa, Nourse, Jamie P., Gandhi, Maher K., Reinke, Petra, Neuhaus, Ruth, Karbasiyan, Mohsen, Gärtner, Barbara, Anagnostopoulos, Ioannis, Riess, Hanno, Trappe, Ralf and Oertel, Stephan (2014). FCY-receptor IIIA polymorphism p.158F has no negative predictive impact on rituximab therapy with and without sequential chemotherapy in CD20-positive post-transplant lymphoproliferative disorder. Journal of Immunology Research, 264723 264723, 1-6. doi: 10.1155/2014/264723

FCY-receptor IIIA polymorphism p.158F has no negative predictive impact on rituximab therapy with and without sequential chemotherapy in CD20-positive post-transplant lymphoproliferative disorder

2014

Journal Article

A new frontier in haematology - combining pharmacokinetic with pharmacodynamic factors to improve choice and dose of drug

Arpon, David Rey, Gandhi, Maher K. and Martin, Jennifer H. (2014). A new frontier in haematology - combining pharmacokinetic with pharmacodynamic factors to improve choice and dose of drug. British Journal of Clinical Pharmacology, 78 (2), 274-281. doi: 10.1111/bcp.12318

A new frontier in haematology - combining pharmacokinetic with pharmacodynamic factors to improve choice and dose of drug

2014

Journal Article

Plasma microRNA are disease response biomarkers in classical Hodgkin lymphoma

Jones, Kimberley, Nourse, Jamie P., Keane, Colm, Bhatnagar, Atul and Gandhi, Maher K. (2014). Plasma microRNA are disease response biomarkers in classical Hodgkin lymphoma. Clinical Cancer Research, 20 (1), 253-264. doi: 10.1158/1078-0432.CCR-13-1024

Plasma microRNA are disease response biomarkers in classical Hodgkin lymphoma

2014

Conference Publication

Noninvasive monitoring of cellular versus acellular tumor DNA from immunoglobulin genes for DLBCL

Kurtz, David Matthew, Green, Michael R., Bratman, Scott Victor, Liu, Chih-Long, Glover, Cynthia, Keane, Colm, Kong, Katie, Faham, Malek, Miklos, David Bernard, Advani, Ranjana H., Levy, Ronald, Hertzberg, Mark S., Gandhi, Maher K., Diehn, Maximilian and Alizadeh, Ash A. (2014). Noninvasive monitoring of cellular versus acellular tumor DNA from immunoglobulin genes for DLBCL. 50th Annual Meeting of the American Society of Clinical Oncology, Chicago IL United States, May 30-June 3, 2014. Alexandria VA, United States: American Society of Clinical Oncology.

Noninvasive monitoring of cellular versus acellular tumor DNA from immunoglobulin genes for DLBCL

2014

Conference Publication

Validation of Elevated Blood Soluble PD-L1 As an Independent Prognostic Marker in Newly Diagnosed Diffuse Large B-Cell Lymphoma (DLBCL)

Fest, Thierry, Cerhan, James R., Gandhi, Maher K., Azzaoui, Imane, Crooks, Pauline, Maurer, Matthew J., Milpied, Noel, Hertzberg, Mark S., Lamy, Thierry, Ansell, Stephen M., Slager, Susan L., Feldman, Andrew L., Roussel, Mikael, Habermann, Thomas M., Ghesquieres, Herve, Witzig, Thomas E., Link, Brian K. and Rossille, Delphine (2014). Validation of Elevated Blood Soluble PD-L1 As an Independent Prognostic Marker in Newly Diagnosed Diffuse Large B-Cell Lymphoma (DLBCL). 56th Annual Meeting of the American Society of Hematology, San Francisco, CA United States, 06-09 December 2014. Washington, DC United States: American Society of Hematology. doi: 10.1182/blood.V124.21.2998.2998

Validation of Elevated Blood Soluble PD-L1 As an Independent Prognostic Marker in Newly Diagnosed Diffuse Large B-Cell Lymphoma (DLBCL)

2013

Conference Publication

HLA-Class I Alleles Impact Susceptibility To EBV+ Classical Hodgkin Lymphoma By Altering EBV Latent Antigen-Specific CD8(+) T-Cell Immune Hierarchies

Gandhi, Maher K., Brennan, Rebekah M., Wockner, Leesa, Chattopadhyay, Pratip K., Roederer, Mario, Price, David A., Cole, David K., Hassan, Brekhna, Beck, Konrad, Thornton, Alycia, Gottlieb, David, Ritchie, David, Seymour, John F., Kumarasinghe, Gayathri, Burrows, Scott R. and Jones, Kimberley (2013). HLA-Class I Alleles Impact Susceptibility To EBV+ Classical Hodgkin Lymphoma By Altering EBV Latent Antigen-Specific CD8(+) T-Cell Immune Hierarchies. 55th Annual Meeting of the American-Society-of-Hematology, New Orleans La, Dec 07-10, 2013. WASHINGTON: AMER SOC HEMATOLOGY.

HLA-Class I Alleles Impact Susceptibility To EBV+ Classical Hodgkin Lymphoma By Altering EBV Latent Antigen-Specific CD8(+) T-Cell Immune Hierarchies

2013

Journal Article

CD4+Tumor infiltrating lymphocytes are prognostic and independent of R-IPI in patients with DLBCL receiving R-CHOP chemo-immunotherapy

Keane, Colm, Gill, Devinder, Vari, Frank, Cross, Donna, Griffiths, Lynn and Gandhi, Maher (2013). CD4+Tumor infiltrating lymphocytes are prognostic and independent of R-IPI in patients with DLBCL receiving R-CHOP chemo-immunotherapy. American Journal of Hematology, 88 (4), 273-276. doi: 10.1002/ajh.23398

CD4+Tumor infiltrating lymphocytes are prognostic and independent of R-IPI in patients with DLBCL receiving R-CHOP chemo-immunotherapy

2013

Journal Article

Serum CD163 and TARC as disease response biomarkers in classical Hodgkin lymphoma

Jones, Kimberley, Vari, Frank, Keane, Colm, Crooks, Pauline, Nourse, Jamie P., Seymour, Louise A., Gottlieb, David, Ritchie, David, Gill, Devinder and Gandhi, Maher K. (2013). Serum CD163 and TARC as disease response biomarkers in classical Hodgkin lymphoma. Clinical Cancer Research, 19 (3), 731-742. doi: 10.1158/1078-0432.CCR-12-2693

Serum CD163 and TARC as disease response biomarkers in classical Hodgkin lymphoma

2013

Conference Publication

FOXP1 truncated isoforms differentially regulate target genes in diffuse large B cell lymphoma.

Camilleri, Emily, Aya-Bonilla, Carlos, Nourse, Jamie, Brown, Philip J., Banham, Alison H., Marlton, Paula, Gandhi, Maher K. and Griffiths, Lyn R. (2013). FOXP1 truncated isoforms differentially regulate target genes in diffuse large B cell lymphoma.. PHILADELPHIA: AMER ASSOC CANCER RESEARCH. doi: 10.1158/1538-7445.TUMIMM2012-B38

FOXP1 truncated isoforms differentially regulate target genes in diffuse large B cell lymphoma.

2013

Journal Article

The Epstein-Barr Virus microRNA BART11-5p targets the early B-cell transcription factor EBF1

Ross, Nathan, Gandhi, Maher K. and Nourse, Jamie P. (2013). The Epstein-Barr Virus microRNA BART11-5p targets the early B-cell transcription factor EBF1. American Journal of Blood Research, 3 (3), 210-224.

The Epstein-Barr Virus microRNA BART11-5p targets the early B-cell transcription factor EBF1

2013

Journal Article

High-resolution loss of heterozygosity screening implicates PTPRJ as a potential tumor suppressor gene that affects susceptibility to non-hodgkin's lymphoma

Aya-Bonilla, C., Green, M.R., Camilleri, E., Benton, M., Keane, C., Marlton, P., Lea, R., Gandhi, M.K. and Griffiths, L.R. (2013). High-resolution loss of heterozygosity screening implicates PTPRJ as a potential tumor suppressor gene that affects susceptibility to non-hodgkin's lymphoma. Genes Chromosomes and Cancer, 52 (5), 467-479. doi: 10.1002/gcc.22044

High-resolution loss of heterozygosity screening implicates PTPRJ as a potential tumor suppressor gene that affects susceptibility to non-hodgkin's lymphoma

2013

Conference Publication

Immunosuppression (IST) Can Be Safely Ceased During Chemotherapy For Post-Transplant Lymphoproliferative Disorders (PTLD) In Renal Transplant Patients

Taylor, Emma, Jones, Mark, Hourigan, Matthew J., Johnson, David W., Gill, Devinder S., Isbel, Nicole, Hawley, Carmel M., Marlton, Paula, Gandhi, Maher K., Campbell, Scott B. and Mollee, Peter (2013). Immunosuppression (IST) Can Be Safely Ceased During Chemotherapy For Post-Transplant Lymphoproliferative Disorders (PTLD) In Renal Transplant Patients. 55th Annual Meeting of the American Society of Hematology, New Orleans, LA United States, 7-10 December 2013. Washington, DC United States: American Society of Hematology.

Immunosuppression (IST) Can Be Safely Ceased During Chemotherapy For Post-Transplant Lymphoproliferative Disorders (PTLD) In Renal Transplant Patients

2013

Journal Article

Primary CNS posttransplant lymphoproliferative disease (PTLD): An international report of 84 cases in the modern era

Evens A.M., Choquet S., Kroll-Desrosiers A.R., Jagadeesh D., Smith S.M., Morschhauser F., Leblond V., Roy R., Barton B., Gordon L.I., Gandhi M.K., Dierickx D., Schiff D., Habermann T.M. and Trappe R. (2013). Primary CNS posttransplant lymphoproliferative disease (PTLD): An international report of 84 cases in the modern era. American Journal of Transplantation, 13 (6), 1512-1522. doi: 10.1111/ajt.12211

Primary CNS posttransplant lymphoproliferative disease (PTLD): An international report of 84 cases in the modern era

2012

Journal Article

Back to basics: the complete blood cell count adds to the ability of immunohistochemistry in diffuse large B-cell lymphoma prognosis

Vari, Frank and Gandhi, Maher K. (2012). Back to basics: the complete blood cell count adds to the ability of immunohistochemistry in diffuse large B-cell lymphoma prognosis. Leukemia & Lymphoma, 53 (11), 2097-2098. doi: 10.3109/10428194.2012.701297

Back to basics: the complete blood cell count adds to the ability of immunohistochemistry in diffuse large B-cell lymphoma prognosis

2012

Journal Article

Homozygous FCGR3A-158V alleles predispose to late onset neutropenia after CHOP-R for diffuse large B-cell lymphoma

Keane, C., Nourse, J. P., Crooks, P., Nguyen-Van, D., Mutsando, H., Mollee, P., Lea, R. A. and Gandhi, M. K. (2012). Homozygous FCGR3A-158V alleles predispose to late onset neutropenia after CHOP-R for diffuse large B-cell lymphoma. Internal Medicine Journal, 42 (10), 1113-1119. doi: 10.1111/j.1445-5994.2011.02587.x

Homozygous FCGR3A-158V alleles predispose to late onset neutropenia after CHOP-R for diffuse large B-cell lymphoma

2012

Journal Article

Expression profiling of Epstein-Barr virus-encoded microRNAs from paraffin-embedded formalin-fixed primary Epstein-Barr virus-positive B-cell lymphoma samples

Nourse, J.P., Crooks, P., Keane, C.., Nguyen-Van, D., Mujaj, S., Ross, N., Jones, K., Vari, F., Han, E., Trappe, R., Fink, S. and Gandhi, M.K. (2012). Expression profiling of Epstein-Barr virus-encoded microRNAs from paraffin-embedded formalin-fixed primary Epstein-Barr virus-positive B-cell lymphoma samples. Journal of Virological Methods, 184 (1-2), 46-54. doi: 10.1016/j.jviromet.2012.05.005

Expression profiling of Epstein-Barr virus-encoded microRNAs from paraffin-embedded formalin-fixed primary Epstein-Barr virus-positive B-cell lymphoma samples

2012

Conference Publication

Lymphocyte Counts in Patients with B-Cell Non-Hodgkin Lymphoma and Correlation with Fc Gamma Receptor Polymorphisms

Talaulikar, Dipti, Cendales, Yvonne Gonzalez, Shadbolt, Bruce, Gandhi, Maher and Warren, Hilary (2012). Lymphocyte Counts in Patients with B-Cell Non-Hodgkin Lymphoma and Correlation with Fc Gamma Receptor Polymorphisms. MALDEN: WILEY-BLACKWELL.

Lymphocyte Counts in Patients with B-Cell Non-Hodgkin Lymphoma and Correlation with Fc Gamma Receptor Polymorphisms

Funding

Current funding

  • 2025 - 2027
    Health Translation Queensland
    2025-26 Supporting Research Translation Centres
    Open grant
  • 2025 - 2027
    Personalized immunotherapy for the treatment of light chain amyloidosis
    Snowdome Haematology Fellowship
    Open grant
  • 2024 - 2029
    Building mRNA Cancer Vaccines for Australia.
    MRFF - National Critical Infrastructure Initiative
    Open grant
  • 2024 - 2029
    BrainCAR19 Study- Treatment of relapsed Primary Brain Lymphoma with CD19 directed CAR-T cells
    NHMRC MRFF CTA - Clinical Trials Activity
    Open grant
  • 2022 - 2027
    An early phase, open label, multi-centre trial of front-line TheRapy for EBv-associated Lymphomas -- 2: TREBL-2 (Stream 6)
    NHMRC MRFF - Rare Cancers, Rare Diseases and Unmet Need
    Open grant
  • 2019 - 2026
    An Open Label, Multicentre, Phase One Study Incorporating Early Application of CAR T cells for Primary Refractory Aggressive Lymphoma
    NHMRC MRFF - Rare Cancers, Rare Diseases and Unmet Need
    Open grant

Past funding

  • 2023 - 2025
    Metabolic Reprogramming of Malignant B-cells Impairs Immune-Fitness of Intratumoral T-Cells in Follicular Lymphoma
    Conquer Cancer AstraZeneca Young Investigator Award
    Open grant
  • 2022 - 2025
    The Development of Biomarker-Directed Immunotherapy in Advanced Stage Follicular Lymphoma Patients
    Snowdome Haematology Fellowship
    Open grant
  • 2020 - 2022
    PiggyBac transposon UCB-CAR19-NK cells: a novel off-the-shelf cellular immunotherapy for children with CD19+ blood cancers
    Children's Hospital Foundation Immunotherapy Research Grants
    Open grant
  • 2019 - 2020
    Indolent Lymphoma: Establishing a prognostic score fit for the modern era
    The Leukaemia Foundation of Australia Limited
    Open grant
  • 2018 - 2025
    An Open label, Multicentre, Phase I study of Ibrutinib, Rituximab and EBV specific T-cells in Patients with EBV-positive Primary or Secondary CNS Lymphoma unsuitable for standard therapies
    NHMRC MRFF - Lifting Clinical Trials Registries Capacity
    Open grant
  • 2018 - 2019
    A novel immunotherapy strategy for lymphoma using artificial microRNA gene targeting
    Metro South Hospital and Health Service
    Open grant
  • 2018 - 2022
    Integrating immunity and genetics in Follicular Lymphoma to establish a prognostic score fit for the modern era
    NHMRC Project Grant
    Open grant
  • 2017 - 2019
    Pre-clinical studies of anti-LAG3 in lymphoma
    Bristol-Myers Squibb Pharmaceuticals Pty Limited
    Open grant
  • 2017
    Improving the evidence base for resource allocation in indolent lymphoma
    Gilead Australia Fellowship
    Open grant
  • 2017 - 2019
    The prognostic utility of the tumour microenvironment in Non-Hodgkin's Lymphoma
    Celgene Pty Ltd
    Open grant
  • 2016 - 2018
    Prognosticator for Follicular lymphoma (FL) and Mantle celly lymphoma (MCL)
    Research Donation Generic
    Open grant
  • 2016 - 2017
    Blood biomarkers in Hodgkin Lymphoma
    PA Research Foundation NHMRC Infrastructure Support
    Open grant
  • 2016
    Establishing a gnotobiotic germ-free mouse facility
    UQ Major Equipment and Infrastructure
    Open grant
  • 2016
    Marshaling NK-cells in the fight against blood cancers: a novel approach
    PA Research Foundation NHMRC Near Miss Grant
    Open grant
  • 2015 - 2018
    A correlative laboratory study of primary CNS lymphoma
    Research Donation Generic
    Open grant
  • 2015 - 2016
    Funding Assistance for Gandhi laboratory
    Metro South Hospital and Health Service
    Open grant
  • 2015 - 2016
    Using single-cell transcriptomics to define T-cell tolerance in EBV+ lymphoma
    PA Research Foundation
    Open grant
  • 2014 - 2018
    Leukaemia Foundation Queensland Chair in Blood Cancer Research (2014-2019)
    Leukaemia Foundation
    Open grant
  • 2014 - 2017
    Circulating Biomarkers in advanced classical Hodgkin Lymphoma
    NHMRC Project Grant
    Open grant
  • 2014
    High throughput gene expression of patient samples via the Nanostring nCounter system
    UQ Major Equipment and Infrastructure
    Open grant
  • 2013 - 2020
    The Diamantina Individualised Oncology Care Centre (DIOCC)
    Australian Cancer Research Foundation
    Open grant
  • 2013 - 2014
    Monocytic myeloid derived suppressor cells and antiCD20-antibody dependent cellular cytotoxicity in diffuse large B-cell lymphoma (Cancer Council Queensland grant administered by PAH)
    Metro South Hospital and Health Service
    Open grant

Supervision

Availability

Professor Maher Gandhi is:
Available for supervision

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Supervision history

Current supervision

Completed supervision

Media

Enquiries

Contact Professor Maher Gandhi directly for media enquiries about:

  • Biomarkers
  • Immunotherapy
  • Lymphoma

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