
Overview
Background
Maher Gandhi received his medical degree in the UK in 1989, and then trained as a haematologist, including a Fellowship in malignant haematology at Princess Margaret Cancer Centre, Toronto. He was awarded a PhD in immunology at Cambridge University under Patrick Sissons. He moved to Brisbane and from 2003-2024 worked as a Senior Staff Specialist (Pre-Eminent Status) in the Haematology / Oncology Department of the Princess Alexandra Hospital. He leads his own laboratory group and has established an international reputation studying the tumour immune microenvironment in lymphoma and its manipulation, with continuous NHMRC/MRFF funding since 2005. He was Chair of Laboratory Sciences for the Australasian Leukaemia and Lymphoma Group between 2010-2016, won the prestigious Australian Society of Medical Research Clinical Research Award in 2010 and in 2012 took up the inaugural John McCaffrey Cancer Council of Queensland / Office of Health and Medical Research Clinical Research Fellowship. Between 2011-2014 he was privileged to serve as Chair of the Metro South Human Research Ethics Committee. In 2013 he was appointed Professor of Experimental Haematology, University of Queensland, based at the Translational Research Institute, in 2014 became the inaugural Leukaemia Foundation Chair of Blood Cancer Research at the University of Queensland Frazer Institute, and was appointed Cancer Program Head in 2016. In 2018 he became Executive Director and Director of Clinical Research at Mater Research. He also continues to head the Blood Cancer Research Group, which is based in Mater Research. In 2025 to current, he was appointed Chief Executive Officer of the Translational Research Institute and its manufacturing branch TM@TRI, to serve Queenslanders by transforming health through collaborative research.
Availability
- Professor Maher Gandhi is:
- Available for supervision
- Media expert
Fields of research
Qualifications
- Bachelor of Medicine Surgery, University of Aberdeen
- Doctor of Philosophy, University of Cambridge
Research interests
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Lymphoma
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Immunotherapy
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Biomarkers
Research impacts
The research of the Blood Cancer Research Laboratory aims to understand the basis of lymphoma; to devise new treatments which are less toxic and more effective; to establish new biomarkers which will help determine the most effective treatment strategies and to monitor response and relapse and understand the development of lymphomas. The group has a strong emphasis on patient material, which it obtains from international and national clinical collaborators. Lymphomas studied includeEBV-associated lymphomas, Hodgkin Lymphoma, PTLD, Diffuse Large B-cell Lymphoma, Follicular Lymphoma and amyloidosis. We utilise a broad range of approaches including genomics, transcriptomics and functional immunoassays, and are conducting a number of MRFF funded cellular therapy studies sponsored by the Australasian Leukaemia and Lymphoma Group.
The Mater Foundation, the Leukaemia Foundation, the Mark Coghlan EBV Lymphoma Project and the Brisbane Girls Grammar School Kirsten Jack Memorial Fund are thanked for their kind support.
Works
Search Professor Maher Gandhi’s works on UQ eSpace
2013
Conference Publication
HLA-Class I Alleles Impact Susceptibility To EBV+ Classical Hodgkin Lymphoma By Altering EBV Latent Antigen-Specific CD8(+) T-Cell Immune Hierarchies
Gandhi, Maher K., Brennan, Rebekah M., Wockner, Leesa, Chattopadhyay, Pratip K., Roederer, Mario, Price, David A., Cole, David K., Hassan, Brekhna, Beck, Konrad, Thornton, Alycia, Gottlieb, David, Ritchie, David, Seymour, John F., Kumarasinghe, Gayathri, Burrows, Scott R. and Jones, Kimberley (2013). HLA-Class I Alleles Impact Susceptibility To EBV+ Classical Hodgkin Lymphoma By Altering EBV Latent Antigen-Specific CD8(+) T-Cell Immune Hierarchies. 55th Annual Meeting of the American-Society-of-Hematology, New Orleans La, Dec 07-10, 2013. WASHINGTON: AMER SOC HEMATOLOGY.
2013
Journal Article
CD4+Tumor infiltrating lymphocytes are prognostic and independent of R-IPI in patients with DLBCL receiving R-CHOP chemo-immunotherapy
Keane, Colm, Gill, Devinder, Vari, Frank, Cross, Donna, Griffiths, Lynn and Gandhi, Maher (2013). CD4+Tumor infiltrating lymphocytes are prognostic and independent of R-IPI in patients with DLBCL receiving R-CHOP chemo-immunotherapy. American Journal of Hematology, 88 (4), 273-276. doi: 10.1002/ajh.23398
2013
Journal Article
Serum CD163 and TARC as disease response biomarkers in classical Hodgkin lymphoma
Jones, Kimberley, Vari, Frank, Keane, Colm, Crooks, Pauline, Nourse, Jamie P., Seymour, Louise A., Gottlieb, David, Ritchie, David, Gill, Devinder and Gandhi, Maher K. (2013). Serum CD163 and TARC as disease response biomarkers in classical Hodgkin lymphoma. Clinical Cancer Research, 19 (3), 731-742. doi: 10.1158/1078-0432.CCR-12-2693
2013
Conference Publication
FOXP1 truncated isoforms differentially regulate target genes in diffuse large B cell lymphoma.
Camilleri, Emily, Aya-Bonilla, Carlos, Nourse, Jamie, Brown, Philip J., Banham, Alison H., Marlton, Paula, Gandhi, Maher K. and Griffiths, Lyn R. (2013). FOXP1 truncated isoforms differentially regulate target genes in diffuse large B cell lymphoma.. PHILADELPHIA: AMER ASSOC CANCER RESEARCH. doi: 10.1158/1538-7445.TUMIMM2012-B38
2013
Journal Article
The Epstein-Barr Virus microRNA BART11-5p targets the early B-cell transcription factor EBF1
Ross, Nathan, Gandhi, Maher K. and Nourse, Jamie P. (2013). The Epstein-Barr Virus microRNA BART11-5p targets the early B-cell transcription factor EBF1. American Journal of Blood Research, 3 (3), 210-224.
2013
Journal Article
High-resolution loss of heterozygosity screening implicates PTPRJ as a potential tumor suppressor gene that affects susceptibility to non-hodgkin's lymphoma
Aya-Bonilla, C., Green, M.R., Camilleri, E., Benton, M., Keane, C., Marlton, P., Lea, R., Gandhi, M.K. and Griffiths, L.R. (2013). High-resolution loss of heterozygosity screening implicates PTPRJ as a potential tumor suppressor gene that affects susceptibility to non-hodgkin's lymphoma. Genes Chromosomes and Cancer, 52 (5), 467-479. doi: 10.1002/gcc.22044
2013
Conference Publication
Immunosuppression (IST) Can Be Safely Ceased During Chemotherapy For Post-Transplant Lymphoproliferative Disorders (PTLD) In Renal Transplant Patients
Taylor, Emma, Jones, Mark, Hourigan, Matthew J., Johnson, David W., Gill, Devinder S., Isbel, Nicole, Hawley, Carmel M., Marlton, Paula, Gandhi, Maher K., Campbell, Scott B. and Mollee, Peter (2013). Immunosuppression (IST) Can Be Safely Ceased During Chemotherapy For Post-Transplant Lymphoproliferative Disorders (PTLD) In Renal Transplant Patients. 55th Annual Meeting of the American Society of Hematology, New Orleans, LA United States, 7-10 December 2013. Washington, DC United States: American Society of Hematology.
2013
Journal Article
Primary CNS posttransplant lymphoproliferative disease (PTLD): An international report of 84 cases in the modern era
Evens A.M., Choquet S., Kroll-Desrosiers A.R., Jagadeesh D., Smith S.M., Morschhauser F., Leblond V., Roy R., Barton B., Gordon L.I., Gandhi M.K., Dierickx D., Schiff D., Habermann T.M. and Trappe R. (2013). Primary CNS posttransplant lymphoproliferative disease (PTLD): An international report of 84 cases in the modern era. American Journal of Transplantation, 13 (6), 1512-1522. doi: 10.1111/ajt.12211
2012
Journal Article
Back to basics: the complete blood cell count adds to the ability of immunohistochemistry in diffuse large B-cell lymphoma prognosis
Vari, Frank and Gandhi, Maher K. (2012). Back to basics: the complete blood cell count adds to the ability of immunohistochemistry in diffuse large B-cell lymphoma prognosis. Leukemia & Lymphoma, 53 (11), 2097-2098. doi: 10.3109/10428194.2012.701297
2012
Journal Article
Homozygous FCGR3A-158V alleles predispose to late onset neutropenia after CHOP-R for diffuse large B-cell lymphoma
Keane, C., Nourse, J. P., Crooks, P., Nguyen-Van, D., Mutsando, H., Mollee, P., Lea, R. A. and Gandhi, M. K. (2012). Homozygous FCGR3A-158V alleles predispose to late onset neutropenia after CHOP-R for diffuse large B-cell lymphoma. Internal Medicine Journal, 42 (10), 1113-1119. doi: 10.1111/j.1445-5994.2011.02587.x
2012
Journal Article
Expression profiling of Epstein-Barr virus-encoded microRNAs from paraffin-embedded formalin-fixed primary Epstein-Barr virus-positive B-cell lymphoma samples
Nourse, J.P., Crooks, P., Keane, C.., Nguyen-Van, D., Mujaj, S., Ross, N., Jones, K., Vari, F., Han, E., Trappe, R., Fink, S. and Gandhi, M.K. (2012). Expression profiling of Epstein-Barr virus-encoded microRNAs from paraffin-embedded formalin-fixed primary Epstein-Barr virus-positive B-cell lymphoma samples. Journal of Virological Methods, 184 (1-2), 46-54. doi: 10.1016/j.jviromet.2012.05.005
2012
Conference Publication
Lymphocyte Counts in Patients with B-Cell Non-Hodgkin Lymphoma and Correlation with Fc Gamma Receptor Polymorphisms
Talaulikar, Dipti, Cendales, Yvonne Gonzalez, Shadbolt, Bruce, Gandhi, Maher and Warren, Hilary (2012). Lymphocyte Counts in Patients with B-Cell Non-Hodgkin Lymphoma and Correlation with Fc Gamma Receptor Polymorphisms. MALDEN: WILEY-BLACKWELL.
2012
Conference Publication
Modulation of the unfolded protein response via XBP1 splicing: a novel mechanism that regulates Natural Killer cell effector function.
Mujaj, Sally, Gandhi, Maher, Vari, Frank and Nourse, Jamie (2012). Modulation of the unfolded protein response via XBP1 splicing: a novel mechanism that regulates Natural Killer cell effector function.. 99th Annual Meeting of the American-Association-of-Immunologists, Boston Ma, May 04-08, 2012. BETHESDA: AMER ASSOC IMMUNOLOGISTS.
2012
Journal Article
EBNA3B-deficient EBV promotes B cell lymphomagenesis in humanized mice and is found in human tumors
White, Robert E., Raemer, Patrick C., Naresh, Kikkeri N., Meixlsperger, Sonja, Pinaud, Laurie, Rooney, Cliona, Savoldo, Barbara, Coutinho, Rita, Boedoer, Csaba, Gribben, John, Ibrahim, Hazem A., Bower, Mark, Nourse, Jamie P., Gandhi, Maher K., Middeldorp, Jaap, Cader, Fathima Z., Murray, Paul, Muenz, Christian and Allday, Martin J. (2012). EBNA3B-deficient EBV promotes B cell lymphomagenesis in humanized mice and is found in human tumors. Journal of Clinical Investigation, 122 (4), 1487-1502. doi: 10.1172/JCI58092
2012
Journal Article
Tumor-specific but not nonspecific cell-free circulating DNA can be used to monitor disease response in lymphoma
Jones, Kimberley, Nourse, Jamie P., Keane, Colm, Crooks, Pauline, Gottlieb, David, Ritchie, David S., Gill, Devinder and Gandhi, Maher K. (2012). Tumor-specific but not nonspecific cell-free circulating DNA can be used to monitor disease response in lymphoma. American Journal of Hematology, 87 (3), 258-265. doi: 10.1002/ajh.22252
2012
Journal Article
High dose methotrexate and extended hours high-flux hemodialysis for the treatment of primary central nervous system lymphoma in a patient with end stage renal disease
Mutsando, Howard, Fahim, Magid, Gill, Devinder S., Hawley, Carmel M., Johnson, David W., Maher, K. Gandhi, Marlton, Paula V., Mar Fan, Helen G. and Mollee, Peter N. (2012). High dose methotrexate and extended hours high-flux hemodialysis for the treatment of primary central nervous system lymphoma in a patient with end stage renal disease. American Journal of Blood Research, 2 (1), 66-70.
2012
Conference Publication
Identification of FOXP1 Transcriptional Targets in Diffuse Large B Cell Lymphoma
Camilleri, Emily T., Aya-Bonilla, Carlos A., Brown, Philip J., Banham, Alison, Marlton, Paula, Gandhi, Maher K. and Griffiths, Lyn R. (2012). Identification of FOXP1 Transcriptional Targets in Diffuse Large B Cell Lymphoma. 54th Annual Meeting and Exposition of the American Society of Hematology (ASH), Atlanta, GA, United States, 8-11 December 2012. Washington, DC, United States: American Society of Hematology.
2012
Book Chapter
Rituximab induced late-onset neutropenia
Keane, Colm, Nourse, Jamie P. and Gandhi, Maher K. (2012). Rituximab induced late-onset neutropenia. Rituximab: Pharmacology, Clinical Uses and Health Effects. (pp. 93-102) Hauppauge, NY United States: Nova Science Publishers.
2012
Journal Article
The KIR2DS2/DL2 genotype is associated with adult persistent/chronic and relapsed immune thrombocytopenia independently of FCGR3a-158 polymorphisms
Nourse, Jamie P., Lea, Rod, Crooks, Pauline, Wright, Gillian, Tran, Huyen, Catalano, John, Brighton, Tim, Grigg, Andrew, Marlton, Paula and Gandhi, Maher K. (2012). The KIR2DS2/DL2 genotype is associated with adult persistent/chronic and relapsed immune thrombocytopenia independently of FCGR3a-158 polymorphisms. Blood Coagulation and Fibrinolysis, 23 (1), 45-50. doi: 10.1097/MBC.0b013e32834d7ce3
2012
Conference Publication
Serum CD163 and TARC in Combination As Disease Response Biomarkers in Classical Hodgkin Lymphoma
Gandhi, Maher K., Vari, Frank, Crooks, Pauline, Keane, Colm, Nourse, Jamie P., Seymour, Louise A., Ritchie, David, Gottlieb, David, Gill, Devinder and Jones, Kimberley (2012). Serum CD163 and TARC in Combination As Disease Response Biomarkers in Classical Hodgkin Lymphoma. 54th Annual Meeting and Exposition of the American-Society-of-Hematology (ASH), Atlanta GA, United States, 8-11 December 2012. Washington, DC United States: American Society of Hematology.
Funding
Current funding
Supervision
Availability
- Professor Maher Gandhi is:
- Available for supervision
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Supervision history
Current supervision
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Doctor Philosophy
Personalised therapy for lymphoma
Principal Advisor
Other advisors: Honorary Professor Kristen Radford
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Doctor Philosophy
Impact of genetics upon the tumour microenvironment in Follicular Lymphoma
Principal Advisor
Other advisors: Dr Joshua Tobin, Dr Soi Law, Associate Professor Colm Keane
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Doctor Philosophy
Impact of genetics upon the tumour microenvironment in Follicular Lymphoma
Principal Advisor
Other advisors: Dr Joshua Tobin, Dr Soi Law, Associate Professor Colm Keane
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Doctor Philosophy
Personalised therapy for lymphoma
Principal Advisor
Other advisors: Honorary Professor Kristen Radford
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Doctor Philosophy
Metabolic Reprogramming of Malignant B-cells Impairs Immune-Fitness of Intratumoral T-Cells in Follicular Lymphoma
Principal Advisor
Other advisors: Dr Joshua Tobin, Dr Soi Law
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Doctor Philosophy
Investigations in the development of cord blood derived, GMP grade cellular immunotherapies
Associate Advisor
Other advisors: Honorary Professor Kristen Radford
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Master Philosophy
Developing Companion Biomarkers Application in Follicular Lymphoma
Associate Advisor
Other advisors: Associate Professor Adam Ewing, Dr Joshua Tobin
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Doctor Philosophy
Development of novel vaccines for cancer immunotherapy
Associate Advisor
Other advisors: Dr Kelvin Tuong, Honorary Professor Kristen Radford
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Doctor Philosophy
Utilising alternative cytokine receptor signalling for enhanced cell-based cancer immunotherapy.
Associate Advisor
Other advisors: Dr Soi Law, Dr Joshua Tobin
Completed supervision
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2022
Doctor Philosophy
A Comprehensive Study of Intratumoural T-cells in Follicular Lymphoma
Principal Advisor
Other advisors: Dr Soi Law, Associate Professor Colm Keane
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2021
Doctor Philosophy
Clinical and Prognostic Tools to Improve Frontline Management Strategies in Follicular Lymphoma
Principal Advisor
Other advisors: Associate Professor Colm Keane
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2020
Doctor Philosophy
The impact of deficient antigen presentation on the tumour microenvironment of diffuse large B cell lymphoma
Principal Advisor
Other advisors: Associate Professor Colm Keane
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2019
Doctor Philosophy
A LABORATORY STUDY OF PRIMARY CENTRAL NERVOUS SYSTEM LYMPHOMA
Principal Advisor
Other advisors: Associate Professor Colm Keane
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2016
Master Philosophy
Killer cell Immunoglobulin-like Receptors in Immune Thrombocytopenia (ITP)
Principal Advisor
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2013
Doctor Philosophy
Novel strategies for monitoring, treating and preventing Epstein Barr virus-associated Lymphomas
Principal Advisor
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2020
Doctor Philosophy
Characterising miRNA - gene network associated with natural killer cell activation
Associate Advisor
Other advisors: Dr Soi Law
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2019
Doctor Philosophy
Deciphering the structure and function of class I cytokine receptors: GHR and GP130
Associate Advisor
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2013
Doctor Philosophy
IRE1-mediated splicing of xbp1 in Natural Killer cells
Associate Advisor
Media
Enquiries
Contact Professor Maher Gandhi directly for media enquiries about:
- Biomarkers
- Immunotherapy
- Lymphoma
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