Overview
Availability
- Associate Professor Jason Lee is:
- Available for supervision
Works
Search Professor Jason Lee’s works on UQ eSpace
2017
Journal Article
Tumor immunoevasion by the conversion of effector NK cells into type 1 innate lymphoid cells
Gao, Yulong, Souza-Fonseca-Guimaraes, Fernando, Bald, Tobias, Ng, Susanna S., Young, Arabella, Ngiow, Shin Foong, Rautela, Jai, Straube, Jasmin, Waddell, Nic, Blake, Stephen J., Yan, Juming, Bartholin, Laurent, Lee, Jason S., Vivier, Eric, Takeda, Kazuyoshi, Messaoudene, Meriem, Zitvogel-, Laurence, Teng, Michele W. L., Belz, Gabrielle T., Engwerda, Christian R., Huntington, Nicholas D., Nakamura, Kyohei, Hoelzel, Michael and Smyth, Mark J. (2017). Tumor immunoevasion by the conversion of effector NK cells into type 1 innate lymphoid cells. Nature Immunology, 18 (9), 1004-1015. doi: 10.1038/ni.3800
2017
Journal Article
G9a drives hypoxia-mediated gene repression for breast cancer cell survival and tumorigenesis
Casciello, Francesco, Al-Ejeh, Fares, Kelly, Greg, Brennan, Donal J., Ngiow, Shin Foong, Young, Arabella, Stoll, Thomas, Windloch, Karolina, Hill, Michelle M., Smyth, Mark J., Gannon, Frank and Lee, Jason S. (2017). G9a drives hypoxia-mediated gene repression for breast cancer cell survival and tumorigenesis. Proceedings of the National Academy of Sciences, 114 (27), 7077-7082. doi: 10.1073/pnas.1618706114
2017
Journal Article
Eomesodermin promotes the development of Type-1 Regulatory T (TR1) cells
Zhang, Ping, Lee, Jason S., Gartlan, Kate H., Schuster, Iona S., Comerford, Iain, Varelias, Antiopi, Ullah, Md Ashik, Vuckovic, Slavica, Koyama, Motoko, Kuns, Rachel D., Locke, Kelly R., Beckett, Kirrilee J., Olver, Stuart D., Samson, Luke D., Montes de Oca, Marcela, de Labastida Rivera, Fabian, Clouston, Andrew D., Belz, Gabrielle T., Blazar, Bruce R., MacDonald, Kelli P., McColl, Shaun R., Thomas, Ranjeny, Engwerda, Christian R., Degli-Esposti, Mariapia A., Kallies, Axel, Tey, Siok-Keen and Hill, Geoffrey R. (2017). Eomesodermin promotes the development of Type-1 Regulatory T (TR1) cells. Science Immunology, 2 (10) eaah7152. doi: 10.1126/sciimmunol.aah7152
2016
Journal Article
Evidence that the 5p12 Variant rs10941679 Confers Susceptibility to Estrogen-Receptor-Positive Breast Cancer through FGF10 and MRPS30 Regulation
Ghoussaini, Maya, French, Juliet D., Michailidou, Kyriaki, Nord, Silje, Beesley, Jonathan, Canisus, Sander, Hillman, Kristine M., Kaufmann, Susanne, Sivakumaran, Haran, Moradi Marjaneh, Mahdi, Lee, Jason S., Dennis, Joe, Bolla, Manjeet K., Wang, Qin, Dicks, Ed, Milne, Roger L., Hopper, John L., Southey, Melissa C., Schmidt, Marjanka K., Broeks, Annegien, Muir, Kenneth, Lophatananon, Artitaya, Fasching, Peter A., Beckmann, Matthias W., Fletcher, Olivia, Johnson, Nichola, Sawyer, Elinor J., Tomlinson, Ian, Burwinkel, Barbara ... kConFab/AOCS Investigators (2016). Evidence that the 5p12 Variant rs10941679 Confers Susceptibility to Estrogen-Receptor-Positive Breast Cancer through FGF10 and MRPS30 Regulation. American Journal of Human Genetics, 99 (4), 903-911. doi: 10.1016/j.ajhg.2016.07.017
2016
Journal Article
Programmed death-1 ligand 2-mediated regulation of the PD-L1 to PD-1 axis is essential for establishing CD4+ T cell immunity
Karunarathne, Deshapriya S., Horne-Debets, Joshua M., Huang, Johnny X., Faleiro, Rebecca, Leow, Chiuan Yee, Amante, Fiona, Watkins, Thomas S., Miles, John J., Dwyer, Patrick J., Stacey, Katryn J., Yarski, Michael, Poh, Chek Meng, Lee, Jason S., Cooper, Matthew A., Rénia, Laurent, Richard, Derek, McCarthy, James S., Sharpe, Arlene H. and Wykes, Michelle N. (2016). Programmed death-1 ligand 2-mediated regulation of the PD-L1 to PD-1 axis is essential for establishing CD4+ T cell immunity. Immunity, 45 (2), 333-345. doi: 10.1016/j.immuni.2016.07.017
2016
Journal Article
Point mutations in Exon 1B of APC Reveal Gastric Adenocarcinoma and Proximal Polyposis of the Stomach as a Familial Adenomatous Polyposis Variant
Li, Jun, Woods, Susan L., Healey, Sue, Beesley, Jonathan, Chen, Xiaoqing, Lee, Jason S., Sivakumaran, Haran, Wayte, Nicci, Nones, Katia, Waterfall, Joshua J., Pearson, John, Patch, Anne-Marie, Senz, Janine, Ferreira, Manuel A., Kaurah, Pardeep, Mackenzie, Robertson, Heravi-Moussavi, Alireza, Hansford, Samantha, Lannagan, Tamsin R. M., Spurdle, Amanda B., Simpson, Peter T., da Silva, Leonard, Lakhani, Sunil R., Clouston, Andrew D., Bettington, Mark, Grimpen, Florian, Busuttil, Rita A., Di Costanzo, Natasha, Boussioutas, Alex ... Chenevix-Trench, Georgia (2016). Point mutations in Exon 1B of APC Reveal Gastric Adenocarcinoma and Proximal Polyposis of the Stomach as a Familial Adenomatous Polyposis Variant. American Journal of Human Genetics, 98 (5), 830-842. doi: 10.1016/j.ajhg.2016.03.001
2016
Journal Article
Breast cancer risk variants at 6q25 display different phenotype associations and regulate ESR1, RMND1 and CCDC170
Dunning, Alison M., Michailidou, Kyriaki, Kuchenbaecker, Karoline B., Thompson, Deborah, French, Juliet D., Beesley, Jonathan, Healey, Catherine S., Kar, Siddhartha, Pooley, Karen A., Lopez-Knowles, Elena, Dicks, Ed, Barrowdale, Daniel, Sinnott-Armstrong, Nicholas A., Sallari, Richard C., Hillman, Kristine M., Kaufmann, Susanne, Sivakumaran, Haran, Marjaneh, Mahdi Moradi, Lee, Jason S., Hills, Margaret, Jarosz, Monika, Drury, Suzie, Canisius, Sander, Bolla, Manjeet K., Dennis, Joe, Wang, Qin, Hopper, John L., Southey, Melissa C., Broeks, Annegien ... Edwards, Stacey L. (2016). Breast cancer risk variants at 6q25 display different phenotype associations and regulate ESR1, RMND1 and CCDC170. Nature Genetics, 48 (4), 374-386. doi: 10.1038/ng.3521
2016
Journal Article
The anticancer effect of chaetocin is enhanced by inhibition of autophagy
Jung, H-J, Seo, I, Casciello, F, Jacquelin, S, Lane, S W, Suh, S-Il, Suh, M-H, Lee, J S and Baek, W-K (2016). The anticancer effect of chaetocin is enhanced by inhibition of autophagy. Cell death & disease, 7 (2) e2098, e2098-e2098. doi: 10.1038/cddis.2016.15
2016
Journal Article
Germline polymorphisms in an enhancer of PSIP1 are associated with progression-free survival in epithelial ovarian cancer
French, Juliet D., Johnatty, Sharon E., Lu, Yi, Beesley, Jonathan, Gao, Bo, Kalimutho, Murugan, Henderson, Michelle J., Russell, Amanda J., Kar, Siddhartha, Chen, Xiaoging, Hillman, Kristine M., Kaufmann, S, Sivakumaran H., O'Reilly, Martin, Wang, Chen, Korbie, Darren J., Lambrechts, Diether, Despierre, Evelyn, Van Nieuwenhuysen, Els, Lambrechts, Sandra, Vergote, Ignace, Karlan, Beth, Lester, Jenny, Orsulic, Sandra, Walsh, Christine, Fasching, Peter A., Beckmann, Matthias W., Ekici, Arif B., Hein, Alexander ... MacGregor, Stuart (2016). Germline polymorphisms in an enhancer of PSIP1 are associated with progression-free survival in epithelial ovarian cancer. Oncotarget, 7 (6), 6353-6368. doi: 10.18632/oncotarget.7047
2015
Journal Article
Functional role of G9a histone methyltransferase in cancer
Casciello, Francesco, Windloch, Karolina, Gannon, Frank and Lee, Jason S. (2015). Functional role of G9a histone methyltransferase in cancer. Frontiers in Immunology, 6 (SEP) 487, 487.1-487.12. doi: 10.3389/fimmu.2015.00487
2015
Journal Article
Long-range modulation of PAG1 expression by 8q21 allergy risk variants
Vicente, Cristina T., Edwards, Stacey L., Hillman, Kristine M., Kaufmann, Susanne, Mitchell, Hayley, Bain, Lisa, Glubb, Dylan M., Lee, Jason S., French, Juliet D. and Ferreira, Manuel A. R. (2015). Long-range modulation of PAG1 expression by 8q21 allergy risk variants. American Journal of Human Genetics, 97 (2) 1909, 329-336. doi: 10.1016/j.ajhg.2015.06.010
2015
Journal Article
DNAM-1 expression marks an alternative program of NK cell maturation
Martinet, Ludovic, FerrariDeAndrade, Lucas, Guillerey, Camille, Lee, Jason S, Liu, Jing, Souza-Fonseca-Guimaraes, Fernando, Hutchinson, Dana S, Kolesnik, Tatiana B, Nicholson, Sandra E, Huntington, Nicholas D and Smyth, Mark J (2015). DNAM-1 expression marks an alternative program of NK cell maturation. Cell Reports, 11 (1), 85-97. doi: 10.1016/j.celrep.2015.03.006
2014
Journal Article
Epigenetic regulation in cancer progression
Baxter, Eva, Windloch, Karolina, Gannon, Frank and Lee, Jason S. (2014). Epigenetic regulation in cancer progression. Cell & Bioscience, 4 (1) 45, 45. doi: 10.1186/2045-3701-4-45
2012
Journal Article
EZH2 generates a methyl degron that is recognized by the DCAF1/DDB1/CUL4 E3 ubiquitin ligase complex
Lee, Ji Min, Lee, Jason S., Kim, Hyunkyung, Kim, Kyeong Kyu, Park, Hyejin, Kim, Ji-Young, Lee, Seung Hoon, Kim, Ik Soo, Kim, Joomyung, Lee, Minkyoung, Chung, Chin Ha, Seo, Sang-Beom, Yoon, Jong-Bok, Ko, Eunyoung, Noh, Dong-Young, Kim, Keun Il and Baek, Sung Hee (2012). EZH2 generates a methyl degron that is recognized by the DCAF1/DDB1/CUL4 E3 ubiquitin ligase complex. Molecular Cell, 48 (4), 572-586. doi: 10.1016/j.molcel.2012.09.004
2011
Journal Article
DNA damage-induced RORα Is crucial for p53 stabilization and increased apoptosis
Kim, Hyunkyung, Lee, Ji Min, Lee, Gina, Bhin, Jinhyuk, Oh, Se Kyu, Kim, Kyeongkyu, Pyo, Ki Eun, Lee, Jason S., Yim, Hwa Young, Kim, Keun Il, Hwang, Daehee, Chung, Jongkyeong and Baek, Sung Hee (2011). DNA damage-induced RORα Is crucial for p53 stabilization and increased apoptosis. Molecular Cell, 44 (5), 797-810. doi: 10.1016/j.molcel.2011.09.023
2011
Journal Article
Hypoxia-induced methylation of a pontin chromatin remodeling factor
Lee, Jason S., Kim, Yunho, Bhin, Jinhyuk, Shin, Hi-Jai R., Nam, Hye Jin, Lee, Seung Hoon, Yoon, Jong-Bok, Binda, Olivier, Gozani, Or, Hwang, Daehee and Baek, Sung Hee (2011). Hypoxia-induced methylation of a pontin chromatin remodeling factor. Proceedings of the National Academy of Sciences of the United States of America, 108 (33), 13510-13515. doi: 10.1073/pnas.1106106108
2010
Journal Article
Induction of cellular apoptosis in human breast cancer by DLBS1425, a Phaleria macrocarpa compound extract, via downregulation of PI3-kinase/AKT pathway
Tandrasasmita, Olivia M., Lee, Jason S., Baek, Sung Hee and Tjandrawinata, Raymond R. (2010). Induction of cellular apoptosis in human breast cancer by DLBS1425, a Phaleria macrocarpa compound extract, via downregulation of PI3-kinase/AKT pathway. Cancer Biology and Therapy, 10 (8), 814-823. doi: 10.4161/cbt.10.8.13085
2010
Journal Article
Negative regulation of hypoxic responses via induced reptin methylation
Lee, Jason S., Kim, Yunho, Kim, Ik Soo, Kim, Bogyou, Choi, Hee June, Lee, Ji Min, Shin, Hi-Jai R., Kim, Jung Hwa, Kim, Ji-Young, Seo, Sang-Beom, Lee, Ho, Binda, Olivier, Gozani, Or, Semenza, Gregg L., Kim, Minhyung, Kim, Keun Il, Hwang, Daehee and Baek, Sung Hee (2010). Negative regulation of hypoxic responses via induced reptin methylation. Molecular Cell, 39 (1), 71-85. doi: 10.1016/j.molcel.2010.06.008
2010
Journal Article
Identification of the KAI1 metastasis suppressor gene as a hypoxia target gene
Kim, Bogyou, Boo, Kyungjin, Lee, Jason S., Kim, Keun Il, Kim, Woo Ho, Cho, Hyun-Jai, Park, Young-Bae, Kim, Hyo-Soo and Baek, Sung Hee (2010). Identification of the KAI1 metastasis suppressor gene as a hypoxia target gene. Biochemical and Biophysical Research Communications, 393 (1), 179-184. doi: 10.1016/j.bbrc.2010.01.118
2010
Journal Article
RORα Attenuates Wnt/β-Catenin Signaling by PKCα-Dependent Phosphorylation in Colon Cancer
Lee, Ji Min, Kim, Ik Soo, Kim, Hyunkyung, Lee, Jason S., Kim, Kyeongkyu, Yim, Hwa Young, Jeong, Jiyeong, Kim, Jung Hwa, Kim, Ji-Young, Lee, Hanna, Seo, Sang-Beom, Kim, Hogeun, Rosenfeld, Michael G., Kim, Keun Il and Baek, Sung Hee (2010). RORα Attenuates Wnt/β-Catenin Signaling by PKCα-Dependent Phosphorylation in Colon Cancer. Molecular Cell, 37 (2), 183-195. doi: 10.1016/j.molcel.2009.12.022
Supervision
Availability
- Associate Professor Jason Lee is:
- Available for supervision
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Supervision history
Current supervision
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Doctor Philosophy
Targeting epigenetic regulation to overcome immunotherapy resistance in cutaneous melanoma
Principal Advisor
Other advisors: Professor Nikolas Haass, Professor Kiarash Khosrotehrani, Dr Abbas Shafiee
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Doctor Philosophy
Circular RNAs as a novel biomarker for ovarian cancer
Principal Advisor
Other advisors: Dr Quan Nguyen
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Doctor Philosophy
Harnessing Epigenetic Plasticity to Develop Effective Novel Therapeutic Strategies for Recurrent Melanoma
Principal Advisor
Other advisors: Associate Professor Mitchell Stark
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Doctor Philosophy
Enhancing pancreatic cancer immunotherapy response by epigenetic inhibition
Principal Advisor
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Doctor Philosophy
Identification of Novel Therapeutic Targets in Rare Aggressive Brain Cancers
Associate Advisor
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Doctor Philosophy
Understanding the interplay of MITF, TFEB and CDK4/6 on lysosome activity in melanoma
Associate Advisor
Other advisors: Professor Nikolas Haass
Completed supervision
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2021
Doctor Philosophy
Investigating Molecular Targets of the DNA Damage Response in Triple Negative Breast Cancer
Associate Advisor
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Media
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