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Dr Danielle Borg
Dr

Danielle Borg

Email: 

Overview

Background

Dr. Borg is a translational scientist with a career spanning both Germany and Australia. She has amassed extensive expertise in cellular biology in regenerative therapies, as well as molecular biology, biochemical, and preclinical methodology in diabetes research. Her leadership in coordinating the newest Queensland longitudinal birth cohort has honed her skills in multidisciplinary teamwork, scientific communication, databank governance and epidemiological study design.

Passionate about innovation, Dr. Borg excels in leveraging communication, engagement, and partnerships to address persistent challenges in clinical research. As a Principal Research Fellow in the Women-Newborn-Children's Services at Gold Coast Hospital and Health Service, she is dedicated to workforce capacity building and integrating clinical expertise with academic knowledge. Her efforts are focused on enhancing research implementation and improving health service evaluation within cross-disciplinary teams, to prioritise healthcare improvement.

Availability

Dr Danielle Borg is:
Available for supervision
Media expert

Qualifications

  • Doctor of Philosophy of Life Science, Technische Universität Dresden
  • Bachelor of Biotechnology, Queensland University of Technology
  • Bachelor (Honours) of Life Science, Queensland University of Technology

Research interests

  • Developmental Origins of Disease

  • Longitudinal pregnancy and birth cohort outcomes

  • Diabetes Early Prediction and Prevention

  • Pancreatic islet dysfunction

Research impacts

Dr Borg is an early-career scientist who has authored 38 peer-reiviewed publications in the field of Women's Health, Diabetes, Biomaterial Transplantation, Islet Transplantation, Stem Cell Biology, RAGE/AGE Biology, and Scientific Engagement. Relative to opportunity with program management roles and carers leave since 2018, her research achievements have been exceptional with a FWCI of 1.91, 22 publications with 158 citations, and 4 publications listed in the top 10% most cited worldwide.

Dr Borg has completed research positions in Germany and Australia and has contributed to organising committees for scientific outreach programs, conferences and global communities. She has been supported by a number of mentors throughout her career and is an avid believer in providing mentorship to support the next generation of researchers. She enjoys supporting indviduals find their passion for their career path.

She currently oversee Queensland’s most comprehensive longitudinal birth cohort, tracking families from preconception to age 5. This research has the potential to provide critical insight into developmental, environmental, and biological factors influencing maternal and child health, identifying key intervention periods to prevent chronic diseases and improve population health. With a biobank of over 60,000 samples, the Queensland Family Cohort will have the ability to inform policymakers on effective evidence-based health strategies for maternal and child health. Our whole family approach has highlighted the importance of partners in healthy pregnancies and mothers’ mental health (https://tinyurl.com/3naf67v8). This work could contribute to national and global knowledge on human developmental origins of disease with practical implications for improving women health and well-being. Dr Borg concurrently holds a Principal Research Fellow position in the Women-Newborn-Children’s Service (WNCS) at Gold Coast HHS (GCHHS), where she develops and co-designs the research agenda and build workforce capacity across seven research groups. These groups cover maternal health, the first 2000 days of life, and child and adolescent community health. By guiding clinical researchers, our evaluations of novel models-of-care have the potential to improve health outcomes for women and children.

Works

Search Professor Danielle Borg’s works on UQ eSpace

56 works between 2009 and 2025

41 - 56 of 56 works

2015

Conference Publication

Gene Therapy Using Recombinant Adeno-Associated Virus Serotype 2/8 Liver-Directed Expression of Srage in Experimental Type 1 Diabetes

Leung, Sherman S., Borg, Danielle J., Paul, Moumita, Sharland, Alexandra F. and Forbes, Josephine M. (2015). Gene Therapy Using Recombinant Adeno-Associated Virus Serotype 2/8 Liver-Directed Expression of Srage in Experimental Type 1 Diabetes. 9th Biennial Meeting of the Australasian-Gene-and-Cell-Therapy-Society (AGCTS), Parkville, VIC Australia, 29 April - 1 May 2015. Hoboken, NJ United States: Wiley-Blackwell.

Gene Therapy Using Recombinant Adeno-Associated Virus Serotype 2/8 Liver-Directed Expression of Srage in Experimental Type 1 Diabetes

2015

Conference Publication

Recombinant human soluble receptor for advanced glycation end product therapy reduces autoimmune diabetes in the NOD mouse model

Leung, Sherman, Borg, Danielle J., McCarthy, Domenica, Zhuang, Aowen, Forbes, Josephine and Ward, Micheal (2015). Recombinant human soluble receptor for advanced glycation end product therapy reduces autoimmune diabetes in the NOD mouse model. 75th Scientific Sessions of the American-Diabetes-Association, Boston, MA United States, 5-9 June 2015. Alexandria, VA United States: American Diabetes Association.

Recombinant human soluble receptor for advanced glycation end product therapy reduces autoimmune diabetes in the NOD mouse model

2015

Journal Article

Decrease in circulating concentrations of soluble receptors for advanced glycation end products at the time of seroconversion to autoantibody positivity in children with prediabetes

Salonen, Kirsi M., Ryhanen, Samppa J., Forbes, Josephine M., Borg, Danielle J., Harkonen, Taina, Ilonen, Jorma, Simell, Olli, Veijola, Riitta, Groop, Per-Henrik and Knip, Mikael (2015). Decrease in circulating concentrations of soluble receptors for advanced glycation end products at the time of seroconversion to autoantibody positivity in children with prediabetes. Diabetes Care, 38 (4), 665-670. doi: 10.2337/dc14-1186

Decrease in circulating concentrations of soluble receptors for advanced glycation end products at the time of seroconversion to autoantibody positivity in children with prediabetes

2015

Conference Publication

Delivery of recombinant human soluble receptor for advanced glycation end products delays autoimmune diabetes in the NOD mouse model

Borg, D. J., Leung, S., Zhuang, A., Fotheringham, A., McCarthy, D., Di Trapani, J., Groop, P. -H., Knip, M. and Forbes, J. (2015). Delivery of recombinant human soluble receptor for advanced glycation end products delays autoimmune diabetes in the NOD mouse model. 51st Annual Meeting of the European-Association-for-the-Study-of-Diabetes (EASD), Stockholm, Sweden, 14-18 September 2015. Heidelberg, Germany: Springer. doi: 10.1007/s00125-015-3687-4

Delivery of recombinant human soluble receptor for advanced glycation end products delays autoimmune diabetes in the NOD mouse model

2015

Conference Publication

Short-term alagebrium chloride (ALT-711) therapy pre-diabetes for the treatment of Type I Diabetes

Borg, D. J., McCarthy, D., Reeves, P., Ward, M. S., Fotheringham, A. K., Gallo, L. A., Harcourt, B. E., Agrawal, N., Steptoe, R. and Forbes, J. M. (2015). Short-term alagebrium chloride (ALT-711) therapy pre-diabetes for the treatment of Type I Diabetes. Immunology of Diabetes Society 14th International Congress, Munich, Germany, 12-16 April 2015.

Short-term alagebrium chloride (ALT-711) therapy pre-diabetes for the treatment of Type I Diabetes

2015

Conference Publication

IL-22-MEDIATED SUPPRESSION OF ISLET INFLAMMATION

McGuckin, Mike, Hasnain, Sumaira Z., Borg, Danielle J., Loudovaris, Thomas, Kay, Thomas W., Thomas, Helen E., Whitehead, Jonathon P., Forbes, Josephine M. and Prins, John B. (2015). IL-22-MEDIATED SUPPRESSION OF ISLET INFLAMMATION. Joint Congress of the International-Pancreas-and-Islet-Transplantation-Association, International-Xenotransplantation-Association and Cell-Transplant-Society, Melbourne Australia, Nov 15-19, 2015. PHILADELPHIA: LIPPINCOTT WILLIAMS & WILKINS.

IL-22-MEDIATED SUPPRESSION OF ISLET INFLAMMATION

2014

Journal Article

Glycemic control in diabetes is restored by therapeutic manipulation of cytokines that regulate beta cell stress

Hasnain, Sumaira Z., Borg, Danielle J., Harcourt, Brooke E., Tong, Hui, Sheng, Yonghua H., Ng, Choa Ping, Das, Indrajit, Wang, Ran, Chen, Alice C.-H., Loudovaris, Thomas, Kay, Thomas W., Thomas, Helen E., Whitehead, Jonathan P., Forbes, Josephine M., Prins, Johannes B. and McGuckin, Michael A. (2014). Glycemic control in diabetes is restored by therapeutic manipulation of cytokines that regulate beta cell stress. Nature Medicine, 20 (12), 1417-1426. doi: 10.1038/nm.3705

Glycemic control in diabetes is restored by therapeutic manipulation of cytokines that regulate beta cell stress

2014

Journal Article

Deletion of bone-marrow-derived receptor for AGEs (RAGE) improves renal function in an experimental mouse model of diabetes

Tesch, Greg, Sourris, Karly C., Summers, Shaun A., McCarthy, Domenica, Ward, Micheal S., Borg, Danielle J., Gallo, Linda A., Fotheringham, Amelia K., Pettit, Allison R., Yap, Felicia Y. T., Harcourt, Brooke E., Tan, Adeline L. Y., Kausman, Joshua Y., Nikolic-Paterson, David, Kitching, Arthur R. and Forbes, Josephine M. (2014). Deletion of bone-marrow-derived receptor for AGEs (RAGE) improves renal function in an experimental mouse model of diabetes. Diabetologia, 57 (9), 1977-1985. doi: 10.1007/s00125-014-3291-z

Deletion of bone-marrow-derived receptor for AGEs (RAGE) improves renal function in an experimental mouse model of diabetes

2014

Journal Article

Mesenchymal stromal cells improve transplanted islet survival and islet function in a syngeneic mouse model

Borg, Danielle J., Weigelt, Marc, Wilhelm, Carmen, Gerlach, Michael, Bickle, Marc, Speier, Stephan, Bonifacio, Ezio and Hommel, Angela (2014). Mesenchymal stromal cells improve transplanted islet survival and islet function in a syngeneic mouse model. Diabetologia, 57 (3), 522-531. doi: 10.1007/s00125-013-3109-4

Mesenchymal stromal cells improve transplanted islet survival and islet function in a syngeneic mouse model

2014

Conference Publication

Flux of advanced glycation end products across the kidney as a contributor to renal disease in diabetes

Leung, C., Fotheringham, A. K., Zhuang, A., Borg, D. J., Ward, M. S., Coughlan, M. T., Mccarthy, D. A., Gallo, L. A., Harcourt, B. E. and Forbes, J. M. (2014). Flux of advanced glycation end products across the kidney as a contributor to renal disease in diabetes. 50th Annual Scientific Meeting of the Australian and New Zealand Society of Nephrology, Melbourne, Australia, 25–27 August 2014. Richmond Australia: Wiley-Blackwell Publishing Asia. doi: 10.1111/nep.12302

Flux of advanced glycation end products across the kidney as a contributor to renal disease in diabetes

2014

Conference Publication

Deficiency of rage in bone marrow cells reduces renal injury in diabetic mice

Tesch, G. H., Sourris, K. C., Summers, S. A., Mccarthy, D., Ward, M. S., Borg, D. J., Gallo, L. A., Fotheringham, A. K., Pettit, A., Yap, F. Y. T., Harcourt, B. E., Tan, A. L. Y., Kausman, J. Y., Nikolic-Paterson, D. J., Kitching, A. R. and Forbes, J. M. (2014). Deficiency of rage in bone marrow cells reduces renal injury in diabetic mice. 50th Annual Scientific Meeting of the Australian and New Zealand Society of Nephrology, Melbourne Australia, 25–27 August 2014. Richmond Australia: Wiley-Blackwell Publishing Asia. doi: 10.1111/nep.12301

Deficiency of rage in bone marrow cells reduces renal injury in diabetic mice

2013

Journal Article

Dietary advanced glycation end products as an environmental contributor to type 1 diabetes

Borg, Danielle J. and Forbes, Josephine M. (2013). Dietary advanced glycation end products as an environmental contributor to type 1 diabetes. IMARS Highlights, 8 (5), 21-22.

Dietary advanced glycation end products as an environmental contributor to type 1 diabetes

2013

Conference Publication

Therapies which lower advanced glycation end products influence experimental autoimmune diabetes in a time dependent manner

Borg, D. J., Yap, F. Y. T., Fotheringham, A. K., Harcourt, B. E., McCarthy, D., Ward, M., Slattery, R., Coughlan, M. T., Kantharidis, P. and Forbes, J. M. (2013). Therapies which lower advanced glycation end products influence experimental autoimmune diabetes in a time dependent manner. 49th Annual Meeting of the European Association for the Study of Diabetes (EASD), Barcelona, Spain, 23 -27 September 2013. Heidelberg, Germany: Springer. doi: 10.1007/s00125-013-3012-z

Therapies which lower advanced glycation end products influence experimental autoimmune diabetes in a time dependent manner

2011

Journal Article

The use of biomaterials in islet transplantation

Borg, Danielle J. and Bonifacio, Ezio (2011). The use of biomaterials in islet transplantation. Current Diabetes Reports, 11 (5), 434-444. doi: 10.1007/s11892-011-0210-2

The use of biomaterials in islet transplantation

2010

Journal Article

Mesenchymal cells appearing in pancreatic tissue culture are bone marrow-derived stem cells with the capacity to improve transplanted islet function

Sordi, Valeria, Melzi, Raffaella, Mercalli, Alessia, Formicola, Roberta, Doglioni, Claudio, Tiboni, Francesca, Ferrari, Giuliana, Nano, Rita, Chwalek, Karolina, Lammert, Eckhard, Bonifacio, Ezio, Borg, Danielle and Piemonti, Lorenzo (2010). Mesenchymal cells appearing in pancreatic tissue culture are bone marrow-derived stem cells with the capacity to improve transplanted islet function. Stem Cells, 28 (1), 140-151. doi: 10.1002/stem.259

Mesenchymal cells appearing in pancreatic tissue culture are bone marrow-derived stem cells with the capacity to improve transplanted islet function

2009

Journal Article

Functional and phenotypic characterization of human keratinocytes expanded in microcarrier culture

Borg, Danielle J., Dawson, Rebecca A., Leavesley, David I., Hutmacher, Dietmar W., Upton, Zee and Malda, Jos (2009). Functional and phenotypic characterization of human keratinocytes expanded in microcarrier culture. Journal of Biomedical Materials Research - Part A, 88 (1), 184-194. doi: 10.1002/jbm.a.31864

Functional and phenotypic characterization of human keratinocytes expanded in microcarrier culture

Funding

Current funding

  • 2024 - 2026
    A state-based Perinatal Family Mental Health Registry
    Queensland Mental Health Commission
    Open grant

Past funding

  • 2016 - 2018
    Advanced Glycation in the development of T1D (Helmsley Charitable Trust - George Eisenbath nPOD award for team science) - Administered by the University of Miami
    University of Miami
    Open grant

Supervision

Availability

Dr Danielle Borg is:
Available for supervision

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Supervision history

Current supervision

Completed supervision

Media

Enquiries

Contact Dr Danielle Borg directly for media enquiries about:

  • Diabetes

Need help?

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communications@uq.edu.au