
Overview
Background
Dr. Borg is a translational scientist with a career spanning both Germany and Australia. She has amassed extensive expertise in cellular biology in regenerative therapies, as well as molecular biology, biochemical, and preclinical methodology in diabetes research. Her leadership in coordinating the newest Queensland longitudinal birth cohort has honed her skills in multidisciplinary teamwork, scientific communication, databank governance and epidemiological study design.
Passionate about innovation, Dr. Borg excels in leveraging communication, engagement, and partnerships to address persistent challenges in clinical research. As a Principal Research Fellow in the Women-Newborn-Children's Services at Gold Coast Hospital and Health Service, she is dedicated to workforce capacity building and integrating clinical expertise with academic knowledge. Her efforts are focused on enhancing research implementation and improving health service evaluation within cross-disciplinary teams, to prioritise healthcare improvement.
Availability
- Dr Danielle Borg is:
- Available for supervision
- Media expert
Fields of research
Qualifications
- Doctor of Philosophy of Life Science, Technische Universität Dresden
- Bachelor of Biotechnology, Queensland University of Technology
- Bachelor (Honours) of Life Science, Queensland University of Technology
Research interests
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Developmental Origins of Disease
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Longitudinal pregnancy and birth cohort outcomes
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Diabetes Early Prediction and Prevention
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Pancreatic islet dysfunction
Research impacts
Dr Borg is an early-career scientist who has authored 38 peer-reiviewed publications in the field of Women's Health, Diabetes, Biomaterial Transplantation, Islet Transplantation, Stem Cell Biology, RAGE/AGE Biology, and Scientific Engagement. Relative to opportunity with program management roles and carers leave since 2018, her research achievements have been exceptional with a FWCI of 1.91, 22 publications with 158 citations, and 4 publications listed in the top 10% most cited worldwide.
Dr Borg has completed research positions in Germany and Australia and has contributed to organising committees for scientific outreach programs, conferences and global communities. She has been supported by a number of mentors throughout her career and is an avid believer in providing mentorship to support the next generation of researchers. She enjoys supporting indviduals find their passion for their career path.
She currently oversee Queensland’s most comprehensive longitudinal birth cohort, tracking families from preconception to age 5. This research has the potential to provide critical insight into developmental, environmental, and biological factors influencing maternal and child health, identifying key intervention periods to prevent chronic diseases and improve population health. With a biobank of over 60,000 samples, the Queensland Family Cohort will have the ability to inform policymakers on effective evidence-based health strategies for maternal and child health. Our whole family approach has highlighted the importance of partners in healthy pregnancies and mothers’ mental health (https://tinyurl.com/3naf67v8). This work could contribute to national and global knowledge on human developmental origins of disease with practical implications for improving women health and well-being. Dr Borg concurrently holds a Principal Research Fellow position in the Women-Newborn-Children’s Service (WNCS) at Gold Coast HHS (GCHHS), where she develops and co-designs the research agenda and build workforce capacity across seven research groups. These groups cover maternal health, the first 2000 days of life, and child and adolescent community health. By guiding clinical researchers, our evaluations of novel models-of-care have the potential to improve health outcomes for women and children.
Works
Search Professor Danielle Borg’s works on UQ eSpace
2015
Conference Publication
Gene Therapy Using Recombinant Adeno-Associated Virus Serotype 2/8 Liver-Directed Expression of Srage in Experimental Type 1 Diabetes
Leung, Sherman S., Borg, Danielle J., Paul, Moumita, Sharland, Alexandra F. and Forbes, Josephine M. (2015). Gene Therapy Using Recombinant Adeno-Associated Virus Serotype 2/8 Liver-Directed Expression of Srage in Experimental Type 1 Diabetes. 9th Biennial Meeting of the Australasian-Gene-and-Cell-Therapy-Society (AGCTS), Parkville, VIC Australia, 29 April - 1 May 2015. Hoboken, NJ United States: Wiley-Blackwell.
2015
Conference Publication
Recombinant human soluble receptor for advanced glycation end product therapy reduces autoimmune diabetes in the NOD mouse model
Leung, Sherman, Borg, Danielle J., McCarthy, Domenica, Zhuang, Aowen, Forbes, Josephine and Ward, Micheal (2015). Recombinant human soluble receptor for advanced glycation end product therapy reduces autoimmune diabetes in the NOD mouse model. 75th Scientific Sessions of the American-Diabetes-Association, Boston, MA United States, 5-9 June 2015. Alexandria, VA United States: American Diabetes Association.
2015
Journal Article
Decrease in circulating concentrations of soluble receptors for advanced glycation end products at the time of seroconversion to autoantibody positivity in children with prediabetes
Salonen, Kirsi M., Ryhanen, Samppa J., Forbes, Josephine M., Borg, Danielle J., Harkonen, Taina, Ilonen, Jorma, Simell, Olli, Veijola, Riitta, Groop, Per-Henrik and Knip, Mikael (2015). Decrease in circulating concentrations of soluble receptors for advanced glycation end products at the time of seroconversion to autoantibody positivity in children with prediabetes. Diabetes Care, 38 (4), 665-670. doi: 10.2337/dc14-1186
2015
Conference Publication
Delivery of recombinant human soluble receptor for advanced glycation end products delays autoimmune diabetes in the NOD mouse model
Borg, D. J., Leung, S., Zhuang, A., Fotheringham, A., McCarthy, D., Di Trapani, J., Groop, P. -H., Knip, M. and Forbes, J. (2015). Delivery of recombinant human soluble receptor for advanced glycation end products delays autoimmune diabetes in the NOD mouse model. 51st Annual Meeting of the European-Association-for-the-Study-of-Diabetes (EASD), Stockholm, Sweden, 14-18 September 2015. Heidelberg, Germany: Springer. doi: 10.1007/s00125-015-3687-4
2015
Conference Publication
Short-term alagebrium chloride (ALT-711) therapy pre-diabetes for the treatment of Type I Diabetes
Borg, D. J., McCarthy, D., Reeves, P., Ward, M. S., Fotheringham, A. K., Gallo, L. A., Harcourt, B. E., Agrawal, N., Steptoe, R. and Forbes, J. M. (2015). Short-term alagebrium chloride (ALT-711) therapy pre-diabetes for the treatment of Type I Diabetes. Immunology of Diabetes Society 14th International Congress, Munich, Germany, 12-16 April 2015.
2015
Conference Publication
IL-22-MEDIATED SUPPRESSION OF ISLET INFLAMMATION
McGuckin, Mike, Hasnain, Sumaira Z., Borg, Danielle J., Loudovaris, Thomas, Kay, Thomas W., Thomas, Helen E., Whitehead, Jonathon P., Forbes, Josephine M. and Prins, John B. (2015). IL-22-MEDIATED SUPPRESSION OF ISLET INFLAMMATION. Joint Congress of the International-Pancreas-and-Islet-Transplantation-Association, International-Xenotransplantation-Association and Cell-Transplant-Society, Melbourne Australia, Nov 15-19, 2015. PHILADELPHIA: LIPPINCOTT WILLIAMS & WILKINS.
2014
Journal Article
Glycemic control in diabetes is restored by therapeutic manipulation of cytokines that regulate beta cell stress
Hasnain, Sumaira Z., Borg, Danielle J., Harcourt, Brooke E., Tong, Hui, Sheng, Yonghua H., Ng, Choa Ping, Das, Indrajit, Wang, Ran, Chen, Alice C.-H., Loudovaris, Thomas, Kay, Thomas W., Thomas, Helen E., Whitehead, Jonathan P., Forbes, Josephine M., Prins, Johannes B. and McGuckin, Michael A. (2014). Glycemic control in diabetes is restored by therapeutic manipulation of cytokines that regulate beta cell stress. Nature Medicine, 20 (12), 1417-1426. doi: 10.1038/nm.3705
2014
Journal Article
Deletion of bone-marrow-derived receptor for AGEs (RAGE) improves renal function in an experimental mouse model of diabetes
Tesch, Greg, Sourris, Karly C., Summers, Shaun A., McCarthy, Domenica, Ward, Micheal S., Borg, Danielle J., Gallo, Linda A., Fotheringham, Amelia K., Pettit, Allison R., Yap, Felicia Y. T., Harcourt, Brooke E., Tan, Adeline L. Y., Kausman, Joshua Y., Nikolic-Paterson, David, Kitching, Arthur R. and Forbes, Josephine M. (2014). Deletion of bone-marrow-derived receptor for AGEs (RAGE) improves renal function in an experimental mouse model of diabetes. Diabetologia, 57 (9), 1977-1985. doi: 10.1007/s00125-014-3291-z
2014
Journal Article
Mesenchymal stromal cells improve transplanted islet survival and islet function in a syngeneic mouse model
Borg, Danielle J., Weigelt, Marc, Wilhelm, Carmen, Gerlach, Michael, Bickle, Marc, Speier, Stephan, Bonifacio, Ezio and Hommel, Angela (2014). Mesenchymal stromal cells improve transplanted islet survival and islet function in a syngeneic mouse model. Diabetologia, 57 (3), 522-531. doi: 10.1007/s00125-013-3109-4
2014
Conference Publication
Flux of advanced glycation end products across the kidney as a contributor to renal disease in diabetes
Leung, C., Fotheringham, A. K., Zhuang, A., Borg, D. J., Ward, M. S., Coughlan, M. T., Mccarthy, D. A., Gallo, L. A., Harcourt, B. E. and Forbes, J. M. (2014). Flux of advanced glycation end products across the kidney as a contributor to renal disease in diabetes. 50th Annual Scientific Meeting of the Australian and New Zealand Society of Nephrology, Melbourne, Australia, 25–27 August 2014. Richmond Australia: Wiley-Blackwell Publishing Asia. doi: 10.1111/nep.12302
2014
Conference Publication
Deficiency of rage in bone marrow cells reduces renal injury in diabetic mice
Tesch, G. H., Sourris, K. C., Summers, S. A., Mccarthy, D., Ward, M. S., Borg, D. J., Gallo, L. A., Fotheringham, A. K., Pettit, A., Yap, F. Y. T., Harcourt, B. E., Tan, A. L. Y., Kausman, J. Y., Nikolic-Paterson, D. J., Kitching, A. R. and Forbes, J. M. (2014). Deficiency of rage in bone marrow cells reduces renal injury in diabetic mice. 50th Annual Scientific Meeting of the Australian and New Zealand Society of Nephrology, Melbourne Australia, 25–27 August 2014. Richmond Australia: Wiley-Blackwell Publishing Asia. doi: 10.1111/nep.12301
2013
Journal Article
Dietary advanced glycation end products as an environmental contributor to type 1 diabetes
Borg, Danielle J. and Forbes, Josephine M. (2013). Dietary advanced glycation end products as an environmental contributor to type 1 diabetes. IMARS Highlights, 8 (5), 21-22.
2013
Conference Publication
Therapies which lower advanced glycation end products influence experimental autoimmune diabetes in a time dependent manner
Borg, D. J., Yap, F. Y. T., Fotheringham, A. K., Harcourt, B. E., McCarthy, D., Ward, M., Slattery, R., Coughlan, M. T., Kantharidis, P. and Forbes, J. M. (2013). Therapies which lower advanced glycation end products influence experimental autoimmune diabetes in a time dependent manner. 49th Annual Meeting of the European Association for the Study of Diabetes (EASD), Barcelona, Spain, 23 -27 September 2013. Heidelberg, Germany: Springer. doi: 10.1007/s00125-013-3012-z
2011
Journal Article
The use of biomaterials in islet transplantation
Borg, Danielle J. and Bonifacio, Ezio (2011). The use of biomaterials in islet transplantation. Current Diabetes Reports, 11 (5), 434-444. doi: 10.1007/s11892-011-0210-2
2010
Journal Article
Mesenchymal cells appearing in pancreatic tissue culture are bone marrow-derived stem cells with the capacity to improve transplanted islet function
Sordi, Valeria, Melzi, Raffaella, Mercalli, Alessia, Formicola, Roberta, Doglioni, Claudio, Tiboni, Francesca, Ferrari, Giuliana, Nano, Rita, Chwalek, Karolina, Lammert, Eckhard, Bonifacio, Ezio, Borg, Danielle and Piemonti, Lorenzo (2010). Mesenchymal cells appearing in pancreatic tissue culture are bone marrow-derived stem cells with the capacity to improve transplanted islet function. Stem Cells, 28 (1), 140-151. doi: 10.1002/stem.259
2009
Journal Article
Functional and phenotypic characterization of human keratinocytes expanded in microcarrier culture
Borg, Danielle J., Dawson, Rebecca A., Leavesley, David I., Hutmacher, Dietmar W., Upton, Zee and Malda, Jos (2009). Functional and phenotypic characterization of human keratinocytes expanded in microcarrier culture. Journal of Biomedical Materials Research - Part A, 88 (1), 184-194. doi: 10.1002/jbm.a.31864
Supervision
Availability
- Dr Danielle Borg is:
- Available for supervision
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Supervision history
Current supervision
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Doctor Philosophy
The impact of the COVID-19 epidemic on infant development via changes to dietary intake and quality, mental health, and the gut microbiome of Queensland families
Associate Advisor
Other advisors: Professor Kym Rae, Associate Professor Marloes Nitert Dekker
Completed supervision
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2020
Doctor Philosophy
Novel dietary factors in diabetic and non-diabetic kidney disease
Associate Advisor
Other advisors: Honorary Professor Josephine Forbes
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2020
Doctor Philosophy
The role of receptor for advanced glycation end products (RAGE) in the development of type 1 diabetes
Associate Advisor
Other advisors: Honorary Professor Kristen Radford, Honorary Professor Josephine Forbes
Media
Enquiries
Contact Dr Danielle Borg directly for media enquiries about:
- Diabetes
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