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Dr Danielle Borg
Dr

Danielle Borg

Email: 

Overview

Background

Dr. Borg is a translational scientist with a career spanning both Germany and Australia. She has amassed extensive expertise in cellular biology in regenerative therapies, as well as molecular biology, biochemical, and preclinical methodology in diabetes research. Her leadership in coordinating the newest Queensland longitudinal birth cohort has honed her skills in multidisciplinary teamwork, scientific communication, databank governance and epidemiological study design.

Passionate about innovation, Dr. Borg excels in leveraging communication, engagement, and partnerships to address persistent challenges in clinical research. As a Principal Research Fellow in the Women-Newborn-Children's Services at Gold Coast Hospital and Health Service, she is dedicated to workforce capacity building and integrating clinical expertise with academic knowledge. Her efforts are focused on enhancing research implementation and improving health service evaluation within cross-disciplinary teams, to prioritise healthcare improvement.

Availability

Dr Danielle Borg is:
Available for supervision
Media expert

Qualifications

  • Doctor of Philosophy of Life Science, Technische Universität Dresden
  • Bachelor of Biotechnology, Queensland University of Technology
  • Bachelor (Honours) of Life Science, Queensland University of Technology

Research interests

  • Developmental Origins of Disease

  • Longitudinal pregnancy and birth cohort outcomes

  • Diabetes Early Prediction and Prevention

  • Pancreatic islet dysfunction

Research impacts

Dr Borg is an early-career scientist who has authored 38 peer-reiviewed publications in the field of Women's Health, Diabetes, Biomaterial Transplantation, Islet Transplantation, Stem Cell Biology, RAGE/AGE Biology, and Scientific Engagement. Relative to opportunity with program management roles and carers leave since 2018, her research achievements have been exceptional with a FWCI of 1.91, 22 publications with 158 citations, and 4 publications listed in the top 10% most cited worldwide.

Dr Borg has completed research positions in Germany and Australia and has contributed to organising committees for scientific outreach programs, conferences and global communities. She has been supported by a number of mentors throughout her career and is an avid believer in providing mentorship to support the next generation of researchers. She enjoys supporting indviduals find their passion for their career path.

She currently oversee Queensland’s most comprehensive longitudinal birth cohort, tracking families from preconception to age 5. This research has the potential to provide critical insight into developmental, environmental, and biological factors influencing maternal and child health, identifying key intervention periods to prevent chronic diseases and improve population health. With a biobank of over 60,000 samples, the Queensland Family Cohort will have the ability to inform policymakers on effective evidence-based health strategies for maternal and child health. Our whole family approach has highlighted the importance of partners in healthy pregnancies and mothers’ mental health (https://tinyurl.com/3naf67v8). This work could contribute to national and global knowledge on human developmental origins of disease with practical implications for improving women health and well-being. Dr Borg concurrently holds a Principal Research Fellow position in the Women-Newborn-Children’s Service (WNCS) at Gold Coast HHS (GCHHS), where she develops and co-designs the research agenda and build workforce capacity across seven research groups. These groups cover maternal health, the first 2000 days of life, and child and adolescent community health. By guiding clinical researchers, our evaluations of novel models-of-care have the potential to improve health outcomes for women and children.

Works

Search Professor Danielle Borg’s works on UQ eSpace

56 works between 2009 and 2025

21 - 40 of 56 works

2021

Journal Article

A decline in planned, but not spontaneous, preterm birth rates in a large Australian tertiary maternity centre during COVID‐19 mitigation measures

Gallo, Linda A., Gallo, Tania F., Borg, Danielle J., Moritz, Karen M., Clifton, Vicki L. and Kumar, Sailesh (2021). A decline in planned, but not spontaneous, preterm birth rates in a large Australian tertiary maternity centre during COVID‐19 mitigation measures. Australian and New Zealand Journal of Obstetrics and Gynaecology, 62 (1) ajo.13406, 62-70. doi: 10.1111/ajo.13406

A decline in planned, but not spontaneous, preterm birth rates in a large Australian tertiary maternity centre during COVID‐19 mitigation measures

2021

Journal Article

Short duration alagebrium chloride therapy prediabetes does not inhibit progression to autoimmune diabetes in an experimental model

Borg, Danielle J., Faridi, Pouya, Giam, Kai Lin, Reeves, Peta, Fotheringham, Amelia K., McCarthy, Domenica A., Leung, Sherman, Ward, Micheal S., Harcourt, Brooke E., Ayala, Rochelle, Scheijen, Jean L., Briskey, David, Dudek, Nadine L., Schalkwijk, Casper G., Steptoe, Raymond, Purcell, Anthony W. and Forbes, Josephine M. (2021). Short duration alagebrium chloride therapy prediabetes does not inhibit progression to autoimmune diabetes in an experimental model. Metabolites, 11 (7) 426, 1-21. doi: 10.3390/metabo11070426

Short duration alagebrium chloride therapy prediabetes does not inhibit progression to autoimmune diabetes in an experimental model

2021

Journal Article

Queensland Family Cohort: a study protocol

Borg, Danielle, Rae, Kym, Fiveash, Corrine, Schagen, Johanna, James-McAlpine, Janelle, Friedlander, Frances, Thurston, Claire, Oliveri, Maria, Harmey, Theresa, Cavanagh, Erika, Edwards, Christopher, Fontanarosa, Davide, Perkins, Tony, de Zubicaray, Greig, Moritz, Karen, Kumar, Sailesh, Clifton, Vicki, Queensland Family Cohort Research Collaborative, Hamilton-Williams, Emma and Bora, Samudragupta (2021). Queensland Family Cohort: a study protocol. BMJ Open, 11 (6) e044463, 1-13. doi: 10.1136/bmjopen-2020-044463

Queensland Family Cohort: a study protocol

2021

Journal Article

The AGE receptor, OST48 drives podocyte foot process effacement and basement membrane expansion (alters structural composition)

Zhuang, Aowen, Yap, Felicia Y. T., Borg, Danielle J., McCarthy, Domenica, Fotheringham, Amelia, Leung, Sherman, Penfold, Sally A., Sourris, Karly C., Coughlan, Melinda T., Schulz, Benjamin L. and Forbes, Josephine M. (2021). The AGE receptor, OST48 drives podocyte foot process effacement and basement membrane expansion (alters structural composition). Endocrinology, Diabetes and Metabolism, 4 (3) e00278, e00278. doi: 10.1002/edm2.278

The AGE receptor, OST48 drives podocyte foot process effacement and basement membrane expansion (alters structural composition)

2020

Other Outputs

Preterm birth rates in a large tertiary Australian maternity centre during COVID-19 mitigation measures

Gallo, Linda A., Gallo, Tania F., Borg, Danielle J., Moritz, Karen M., Clifton, Vicki L. and Kumar, Sailesh (2020). Preterm birth rates in a large tertiary Australian maternity centre during COVID-19 mitigation measures.

Preterm birth rates in a large tertiary Australian maternity centre during COVID-19 mitigation measures

2020

Journal Article

Circulating levels of the soluble receptor for AGE (sRAGE) during escalating oral glucose dosages and corresponding isoglycaemic i.v. glucose infusions in individuals with and without type 2 diabetes

Fotheringham, Amelia K., Bagger, Jonatan I., Borg, Danielle J., McCarthy, Domenica A., Holst, Jens J., Vilsbøll, Tina, Knop, Filip K. and Forbes, Josephine M. (2020). Circulating levels of the soluble receptor for AGE (sRAGE) during escalating oral glucose dosages and corresponding isoglycaemic i.v. glucose infusions in individuals with and without type 2 diabetes. Nutrients, 12 (10) 2928, 2928-12. doi: 10.3390/nu12102928

Circulating levels of the soluble receptor for AGE (sRAGE) during escalating oral glucose dosages and corresponding isoglycaemic i.v. glucose infusions in individuals with and without type 2 diabetes

2019

Conference Publication

Exploring AGE and sRAGE regulation in response to oral and intravenous glucose loads in individuals with recently diagnosed type 2 diabetes

Fotheringham, A. K., Bagger, J. I., Borg, D. J., McCarthy, D., Vilsboll, T., Knop, F. K. and Forbes, J. M. (2019). Exploring AGE and sRAGE regulation in response to oral and intravenous glucose loads in individuals with recently diagnosed type 2 diabetes. 55th Annual Meeting of the European Association for the Study of Diabetes (EASD), Barcelona, Spain, 16-20 September 2019 . New York, NY, United States: Springer.

Exploring AGE and sRAGE regulation in response to oral and intravenous glucose loads in individuals with recently diagnosed type 2 diabetes

2017

Journal Article

Perinatal exposure to high dietary advanced glycation end products in transgenic NOD8.3 mice leads to pancreatic beta cell dysfunction

Borg, Danielle J., Yap, Felicia Y. T., Keshvari, Sahar, Simmons, David G., Gallo, Linda A., Fotheringham, Amelia K., Zhuang, Aowen, Slattery, Robyn M., Hasnain, Sumaira Z., Coughlan, Melinda T., Kantharidis, Phillip and Forbes, Josephine M. (2017). Perinatal exposure to high dietary advanced glycation end products in transgenic NOD8.3 mice leads to pancreatic beta cell dysfunction. Islets, 10 (1), 10-24. doi: 10.1080/19382014.2017.1405189

Perinatal exposure to high dietary advanced glycation end products in transgenic NOD8.3 mice leads to pancreatic beta cell dysfunction

2017

Journal Article

Targeted mitochondrial therapy using MitoQ shows equivalent renoprotection to angiotensin converting enzyme inhibition but no combined synergy in diabetes

Ward, Micheal S.., Flemming, Nicole B., Gallo, Linda A., Fotheringham, Amelia K., McCarthy, Domenica A., Zhuang, Aowen, Tang, Peter H., Borg, Danielle J., Shaw, Hannah, Harvie, Benjamin, Briskey, David R., Roberts, Llion A., Plan, Manuel R., Murphy, Michael P., Hodson, Mark P. and Forbes, Josephine M. (2017). Targeted mitochondrial therapy using MitoQ shows equivalent renoprotection to angiotensin converting enzyme inhibition but no combined synergy in diabetes. Scientific Reports, 7 (1) 15190, 15190. doi: 10.1038/s41598-017-15589-x

Targeted mitochondrial therapy using MitoQ shows equivalent renoprotection to angiotensin converting enzyme inhibition but no combined synergy in diabetes

2017

Journal Article

Engaging rural Australian communities in national science week helps increase visibility for women researchers

Hardy, Margaret C., Desselle, Mathilde R., the 2016 Catch a Rising Star Consortium, Allen, Jennifer, Andrews, Katherine T., Barrington, Dani J., Borg, Danielle, Butler, Kaylene, Colvin, Rebecca, Cooper, Tarni Louisa, Furlong, Emily, Hugo, Honor, Johnston, Elecia, Iacona, Gwenllian, Kenkel, Carly, Kuempel, Caitlin, Khosla, Amie, Langbecker, Danette, Liddle, Jacki, Lucia, Diana, Lussini, Vanessa, Nazareth, Lynn, Peel, Alison, Saunders, Megan, Smith, Meaghan and Velasquez, Johana Tello (2017). Engaging rural Australian communities in national science week helps increase visibility for women researchers. Royal Society Open Science, 4 (10) 170548, 170548. doi: 10.1098/rsos.170548

Engaging rural Australian communities in national science week helps increase visibility for women researchers

2017

Conference Publication

Using the Geometric Framework to Explore the Longitudinal Effects of Dietary Macronutrient Consumption On Markers of Kidney Aging

Fotheringham, A. K., Solon-Biet, S. M., Mcmahon, A. C., Ballard, W. O., Ruohonen, K., Borg, D. J., Raubenheimer, D., Le Couteur, D. G., Simpson, S. J. and Forbes, J. M. (2017). Using the Geometric Framework to Explore the Longitudinal Effects of Dietary Macronutrient Consumption On Markers of Kidney Aging. HOBOKEN: WILEY.

Using the Geometric Framework to Explore the Longitudinal Effects of Dietary Macronutrient Consumption On Markers of Kidney Aging

2017

Conference Publication

Lifetime dietary macronutrient intake ratios alter kidney function and structure into old age

Fotheringham, A. K., Solon-Biet, S. M., McMahon, A. C., Ballard, W. O., Ruohonen, K., Borg, D. J., Raubenheimer, D., Le Couteur, D. G., Simpson, S. J. and Forbes, J. M. (2017). Lifetime dietary macronutrient intake ratios alter kidney function and structure into old age. 53rd Annual Meeting of the European-Association-for-the-Study-of-Diabetes (EASD), Lisbon Portugal, Sep 11-15, 2017. NEW YORK: SPRINGER.

Lifetime dietary macronutrient intake ratios alter kidney function and structure into old age

2017

Journal Article

The effect of interleukin-22 treatment on autoimmune diabetes in the NOD mouse

Borg, Danielle J., Wang, Ran, Murray, Lydia, Tong, Hui, Steptoe, Raymond J., McGuckin, Michael A. and Hasnain, Sumaira Z. (2017). The effect of interleukin-22 treatment on autoimmune diabetes in the NOD mouse. Diabetologia, 60 (11), 1-6. doi: 10.1007/s00125-017-4392-2

The effect of interleukin-22 treatment on autoimmune diabetes in the NOD mouse

2016

Journal Article

Macroporous biohybrid cryogels for co-housing pancreatic islets with mesenchymal stromal cells

Borg, Danielle J., Welzel, Petra B., Grimmer, Milauscha, Friedrichs, Jens, Weigelt, Marc, Wilhelm, Carmen, Prewitz, Marina, Stissel, Aline, Hommel, Angela, Kurth, Thomas, Freudenberg, Uwe, Bonifacio, Ezio and Werner, Carsten (2016). Macroporous biohybrid cryogels for co-housing pancreatic islets with mesenchymal stromal cells. Acta Biomaterialia, 44, 178-187. doi: 10.1016/j.actbio.2016.08.007

Macroporous biohybrid cryogels for co-housing pancreatic islets with mesenchymal stromal cells

2016

Journal Article

Receptor for advanced glycation end products (RAGE) in type 1 diabetes pathogenesis

Leung, Sherman S., Forbes, Josephine M. and Borg, Danielle J. (2016). Receptor for advanced glycation end products (RAGE) in type 1 diabetes pathogenesis. Current Diabetes Reports, 16 (10) 100, 100. doi: 10.1007/s11892-016-0782-y

Receptor for advanced glycation end products (RAGE) in type 1 diabetes pathogenesis

2016

Journal Article

Targeting advanced glycation with pharmaceutical agents: where are we now?

Borg, Danielle J. and Forbes, Josephine M. (2016). Targeting advanced glycation with pharmaceutical agents: where are we now?. Glycoconjugate Journal, 33 (4), 653-670. doi: 10.1007/s10719-016-9691-1

Targeting advanced glycation with pharmaceutical agents: where are we now?

2016

Journal Article

Once daily administration of the SGLT2 inhibitor, empagliflozin, attenuates markers of renal fibrosis without improving albuminuria in diabetic db/db mice

Gallo, Linda A., Ward, Micheal S., Fotheringham, Amelia K., Zhuang, Aowen, Borg, Danielle J., Flemming, Nicole B., Harvie, Ben M., Kinneally, Toni L., Yeh, Shang-Ming, McCarthy, Domenica A., Koepsell, Hermann, Vallon, Volker, Pollock, Carol, Panchapakesan, Usha and Forbes, Josephine M. (2016). Once daily administration of the SGLT2 inhibitor, empagliflozin, attenuates markers of renal fibrosis without improving albuminuria in diabetic db/db mice. Scientific Reports, 6 (1) 26428, 28124. doi: 10.1038/srep26428

Once daily administration of the SGLT2 inhibitor, empagliflozin, attenuates markers of renal fibrosis without improving albuminuria in diabetic db/db mice

2016

Journal Article

Antigen-encoding bone marrow terminates islet-directed memory CD8+ T-cell responses to alleviate islet transplant rejection

Coleman, Miranda A., Jessup, Claire F., Bridge, Jennifer A., Overgaard, Nana H., Penko, Daniella, Walters, Stacey, Borg, Danielle J., Galea, Ryan, Forbes, Josephine M., Thomas, Ranjeny, Coates, Patrick T. C., Grey, Shane T., Wells, James W. and Steptoe, Raymond J. (2016). Antigen-encoding bone marrow terminates islet-directed memory CD8+ T-cell responses to alleviate islet transplant rejection. Diabetes, 65 (5), 1328-1340. doi: 10.2337/db15-1418

Antigen-encoding bone marrow terminates islet-directed memory CD8+ T-cell responses to alleviate islet transplant rejection

2015

Conference Publication

IL-22-mediated suppression of islet inflammation

McGuckin, Mike, Hasnain, Sumaira Z., Borg, Danielle J., Loudovaris, Thomas, Kay, Thomas W., Thomas, Helen E., Whitehead, Jonathon P., Forbes, Josephine M. and Prins, John B. (2015). IL-22-mediated suppression of islet inflammation. IPITA/IXA/CTS Joint Congress, Melbourne Australia, Nov 15-19, 2015. HOBOKEN: LIPPINCOTT WILLIAMS & WILKINS.

IL-22-mediated suppression of islet inflammation

2015

Conference Publication

Human soluble receptor for advanced glycation end products therapy reduces autoimmune diabetes in the non-obese diabetic mouse

Leung, S. S.-Y., Borg, D. J., McCarthy, D., Zhuang, A., Fotheringham, A., Di Trapani, G., Groop, P.-H., Knip, M. and Forbes, J. (2015). Human soluble receptor for advanced glycation end products therapy reduces autoimmune diabetes in the non-obese diabetic mouse. Joint Annual Conference of the International Society for Pediatric and Adolescent Diabetes and Australasian Paediatric Endocrine Group (ISPAD+APEG 2015), Brisbane, QLD Australia, 7-10 October 2015. Hoboken, NJ USA: Wiley-Blackwell Publishing. doi: 10.1111/pedi.12309

Human soluble receptor for advanced glycation end products therapy reduces autoimmune diabetes in the non-obese diabetic mouse

Funding

Current funding

  • 2024 - 2026
    A state-based Perinatal Family Mental Health Registry
    Queensland Mental Health Commission
    Open grant

Past funding

  • 2016 - 2018
    Advanced Glycation in the development of T1D (Helmsley Charitable Trust - George Eisenbath nPOD award for team science) - Administered by the University of Miami
    University of Miami
    Open grant

Supervision

Availability

Dr Danielle Borg is:
Available for supervision

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Supervision history

Current supervision

Completed supervision

Media

Enquiries

Contact Dr Danielle Borg directly for media enquiries about:

  • Diabetes

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