
Overview
Background
Dr. Borg is a translational scientist with a career spanning both Germany and Australia. She has amassed extensive expertise in cellular biology in regenerative therapies, as well as molecular biology, biochemical, and preclinical methodology in diabetes research. Her leadership in coordinating the newest Queensland longitudinal birth cohort has honed her skills in multidisciplinary teamwork, scientific communication, databank governance and epidemiological study design.
Passionate about innovation, Dr. Borg excels in leveraging communication, engagement, and partnerships to address persistent challenges in clinical research. As a Principal Research Fellow in the Women-Newborn-Children's Services at Gold Coast Hospital and Health Service, she is dedicated to workforce capacity building and integrating clinical expertise with academic knowledge. Her efforts are focused on enhancing research implementation and improving health service evaluation within cross-disciplinary teams, to prioritise healthcare improvement.
Availability
- Dr Danielle Borg is:
- Available for supervision
- Media expert
Fields of research
Qualifications
- Doctor of Philosophy of Life Science, Technische Universität Dresden
- Bachelor of Biotechnology, Queensland University of Technology
- Bachelor (Honours) of Life Science, Queensland University of Technology
Research interests
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Developmental Origins of Disease
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Longitudinal pregnancy and birth cohort outcomes
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Diabetes Early Prediction and Prevention
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Pancreatic islet dysfunction
Research impacts
Dr Borg is an early-career scientist who has authored 38 peer-reiviewed publications in the field of Women's Health, Diabetes, Biomaterial Transplantation, Islet Transplantation, Stem Cell Biology, RAGE/AGE Biology, and Scientific Engagement. Relative to opportunity with program management roles and carers leave since 2018, her research achievements have been exceptional with a FWCI of 1.91, 22 publications with 158 citations, and 4 publications listed in the top 10% most cited worldwide.
Dr Borg has completed research positions in Germany and Australia and has contributed to organising committees for scientific outreach programs, conferences and global communities. She has been supported by a number of mentors throughout her career and is an avid believer in providing mentorship to support the next generation of researchers. She enjoys supporting indviduals find their passion for their career path.
She currently oversee Queensland’s most comprehensive longitudinal birth cohort, tracking families from preconception to age 5. This research has the potential to provide critical insight into developmental, environmental, and biological factors influencing maternal and child health, identifying key intervention periods to prevent chronic diseases and improve population health. With a biobank of over 60,000 samples, the Queensland Family Cohort will have the ability to inform policymakers on effective evidence-based health strategies for maternal and child health. Our whole family approach has highlighted the importance of partners in healthy pregnancies and mothers’ mental health (https://tinyurl.com/3naf67v8). This work could contribute to national and global knowledge on human developmental origins of disease with practical implications for improving women health and well-being. Dr Borg concurrently holds a Principal Research Fellow position in the Women-Newborn-Children’s Service (WNCS) at Gold Coast HHS (GCHHS), where she develops and co-designs the research agenda and build workforce capacity across seven research groups. These groups cover maternal health, the first 2000 days of life, and child and adolescent community health. By guiding clinical researchers, our evaluations of novel models-of-care have the potential to improve health outcomes for women and children.
Works
Search Professor Danielle Borg’s works on UQ eSpace
2021
Journal Article
A decline in planned, but not spontaneous, preterm birth rates in a large Australian tertiary maternity centre during COVID‐19 mitigation measures
Gallo, Linda A., Gallo, Tania F., Borg, Danielle J., Moritz, Karen M., Clifton, Vicki L. and Kumar, Sailesh (2021). A decline in planned, but not spontaneous, preterm birth rates in a large Australian tertiary maternity centre during COVID‐19 mitigation measures. Australian and New Zealand Journal of Obstetrics and Gynaecology, 62 (1) ajo.13406, 62-70. doi: 10.1111/ajo.13406
2021
Journal Article
Short duration alagebrium chloride therapy prediabetes does not inhibit progression to autoimmune diabetes in an experimental model
Borg, Danielle J., Faridi, Pouya, Giam, Kai Lin, Reeves, Peta, Fotheringham, Amelia K., McCarthy, Domenica A., Leung, Sherman, Ward, Micheal S., Harcourt, Brooke E., Ayala, Rochelle, Scheijen, Jean L., Briskey, David, Dudek, Nadine L., Schalkwijk, Casper G., Steptoe, Raymond, Purcell, Anthony W. and Forbes, Josephine M. (2021). Short duration alagebrium chloride therapy prediabetes does not inhibit progression to autoimmune diabetes in an experimental model. Metabolites, 11 (7) 426, 1-21. doi: 10.3390/metabo11070426
2021
Journal Article
Queensland Family Cohort: a study protocol
Borg, Danielle, Rae, Kym, Fiveash, Corrine, Schagen, Johanna, James-McAlpine, Janelle, Friedlander, Frances, Thurston, Claire, Oliveri, Maria, Harmey, Theresa, Cavanagh, Erika, Edwards, Christopher, Fontanarosa, Davide, Perkins, Tony, de Zubicaray, Greig, Moritz, Karen, Kumar, Sailesh, Clifton, Vicki, Queensland Family Cohort Research Collaborative, Hamilton-Williams, Emma and Bora, Samudragupta (2021). Queensland Family Cohort: a study protocol. BMJ Open, 11 (6) e044463, 1-13. doi: 10.1136/bmjopen-2020-044463
2021
Journal Article
The AGE receptor, OST48 drives podocyte foot process effacement and basement membrane expansion (alters structural composition)
Zhuang, Aowen, Yap, Felicia Y. T., Borg, Danielle J., McCarthy, Domenica, Fotheringham, Amelia, Leung, Sherman, Penfold, Sally A., Sourris, Karly C., Coughlan, Melinda T., Schulz, Benjamin L. and Forbes, Josephine M. (2021). The AGE receptor, OST48 drives podocyte foot process effacement and basement membrane expansion (alters structural composition). Endocrinology, Diabetes and Metabolism, 4 (3) e00278, e00278. doi: 10.1002/edm2.278
2020
Other Outputs
Preterm birth rates in a large tertiary Australian maternity centre during COVID-19 mitigation measures
Gallo, Linda A., Gallo, Tania F., Borg, Danielle J., Moritz, Karen M., Clifton, Vicki L. and Kumar, Sailesh (2020). Preterm birth rates in a large tertiary Australian maternity centre during COVID-19 mitigation measures.
2020
Journal Article
Circulating levels of the soluble receptor for AGE (sRAGE) during escalating oral glucose dosages and corresponding isoglycaemic i.v. glucose infusions in individuals with and without type 2 diabetes
Fotheringham, Amelia K., Bagger, Jonatan I., Borg, Danielle J., McCarthy, Domenica A., Holst, Jens J., Vilsbøll, Tina, Knop, Filip K. and Forbes, Josephine M. (2020). Circulating levels of the soluble receptor for AGE (sRAGE) during escalating oral glucose dosages and corresponding isoglycaemic i.v. glucose infusions in individuals with and without type 2 diabetes. Nutrients, 12 (10) 2928, 2928-12. doi: 10.3390/nu12102928
2019
Conference Publication
Exploring AGE and sRAGE regulation in response to oral and intravenous glucose loads in individuals with recently diagnosed type 2 diabetes
Fotheringham, A. K., Bagger, J. I., Borg, D. J., McCarthy, D., Vilsboll, T., Knop, F. K. and Forbes, J. M. (2019). Exploring AGE and sRAGE regulation in response to oral and intravenous glucose loads in individuals with recently diagnosed type 2 diabetes. 55th Annual Meeting of the European Association for the Study of Diabetes (EASD), Barcelona, Spain, 16-20 September 2019 . New York, NY, United States: Springer.
2017
Journal Article
Perinatal exposure to high dietary advanced glycation end products in transgenic NOD8.3 mice leads to pancreatic beta cell dysfunction
Borg, Danielle J., Yap, Felicia Y. T., Keshvari, Sahar, Simmons, David G., Gallo, Linda A., Fotheringham, Amelia K., Zhuang, Aowen, Slattery, Robyn M., Hasnain, Sumaira Z., Coughlan, Melinda T., Kantharidis, Phillip and Forbes, Josephine M. (2017). Perinatal exposure to high dietary advanced glycation end products in transgenic NOD8.3 mice leads to pancreatic beta cell dysfunction. Islets, 10 (1), 10-24. doi: 10.1080/19382014.2017.1405189
2017
Journal Article
Targeted mitochondrial therapy using MitoQ shows equivalent renoprotection to angiotensin converting enzyme inhibition but no combined synergy in diabetes
Ward, Micheal S.., Flemming, Nicole B., Gallo, Linda A., Fotheringham, Amelia K., McCarthy, Domenica A., Zhuang, Aowen, Tang, Peter H., Borg, Danielle J., Shaw, Hannah, Harvie, Benjamin, Briskey, David R., Roberts, Llion A., Plan, Manuel R., Murphy, Michael P., Hodson, Mark P. and Forbes, Josephine M. (2017). Targeted mitochondrial therapy using MitoQ shows equivalent renoprotection to angiotensin converting enzyme inhibition but no combined synergy in diabetes. Scientific Reports, 7 (1) 15190, 15190. doi: 10.1038/s41598-017-15589-x
2017
Journal Article
Engaging rural Australian communities in national science week helps increase visibility for women researchers
Hardy, Margaret C., Desselle, Mathilde R., the 2016 Catch a Rising Star Consortium, Allen, Jennifer, Andrews, Katherine T., Barrington, Dani J., Borg, Danielle, Butler, Kaylene, Colvin, Rebecca, Cooper, Tarni Louisa, Furlong, Emily, Hugo, Honor, Johnston, Elecia, Iacona, Gwenllian, Kenkel, Carly, Kuempel, Caitlin, Khosla, Amie, Langbecker, Danette, Liddle, Jacki, Lucia, Diana, Lussini, Vanessa, Nazareth, Lynn, Peel, Alison, Saunders, Megan, Smith, Meaghan and Velasquez, Johana Tello (2017). Engaging rural Australian communities in national science week helps increase visibility for women researchers. Royal Society Open Science, 4 (10) 170548, 170548. doi: 10.1098/rsos.170548
2017
Conference Publication
Using the Geometric Framework to Explore the Longitudinal Effects of Dietary Macronutrient Consumption On Markers of Kidney Aging
Fotheringham, A. K., Solon-Biet, S. M., Mcmahon, A. C., Ballard, W. O., Ruohonen, K., Borg, D. J., Raubenheimer, D., Le Couteur, D. G., Simpson, S. J. and Forbes, J. M. (2017). Using the Geometric Framework to Explore the Longitudinal Effects of Dietary Macronutrient Consumption On Markers of Kidney Aging. HOBOKEN: WILEY.
2017
Conference Publication
Lifetime dietary macronutrient intake ratios alter kidney function and structure into old age
Fotheringham, A. K., Solon-Biet, S. M., McMahon, A. C., Ballard, W. O., Ruohonen, K., Borg, D. J., Raubenheimer, D., Le Couteur, D. G., Simpson, S. J. and Forbes, J. M. (2017). Lifetime dietary macronutrient intake ratios alter kidney function and structure into old age. 53rd Annual Meeting of the European-Association-for-the-Study-of-Diabetes (EASD), Lisbon Portugal, Sep 11-15, 2017. NEW YORK: SPRINGER.
2017
Journal Article
The effect of interleukin-22 treatment on autoimmune diabetes in the NOD mouse
Borg, Danielle J., Wang, Ran, Murray, Lydia, Tong, Hui, Steptoe, Raymond J., McGuckin, Michael A. and Hasnain, Sumaira Z. (2017). The effect of interleukin-22 treatment on autoimmune diabetes in the NOD mouse. Diabetologia, 60 (11), 1-6. doi: 10.1007/s00125-017-4392-2
2016
Journal Article
Macroporous biohybrid cryogels for co-housing pancreatic islets with mesenchymal stromal cells
Borg, Danielle J., Welzel, Petra B., Grimmer, Milauscha, Friedrichs, Jens, Weigelt, Marc, Wilhelm, Carmen, Prewitz, Marina, Stissel, Aline, Hommel, Angela, Kurth, Thomas, Freudenberg, Uwe, Bonifacio, Ezio and Werner, Carsten (2016). Macroporous biohybrid cryogels for co-housing pancreatic islets with mesenchymal stromal cells. Acta Biomaterialia, 44, 178-187. doi: 10.1016/j.actbio.2016.08.007
2016
Journal Article
Receptor for advanced glycation end products (RAGE) in type 1 diabetes pathogenesis
Leung, Sherman S., Forbes, Josephine M. and Borg, Danielle J. (2016). Receptor for advanced glycation end products (RAGE) in type 1 diabetes pathogenesis. Current Diabetes Reports, 16 (10) 100, 100. doi: 10.1007/s11892-016-0782-y
2016
Journal Article
Targeting advanced glycation with pharmaceutical agents: where are we now?
Borg, Danielle J. and Forbes, Josephine M. (2016). Targeting advanced glycation with pharmaceutical agents: where are we now?. Glycoconjugate Journal, 33 (4), 653-670. doi: 10.1007/s10719-016-9691-1
2016
Journal Article
Once daily administration of the SGLT2 inhibitor, empagliflozin, attenuates markers of renal fibrosis without improving albuminuria in diabetic db/db mice
Gallo, Linda A., Ward, Micheal S., Fotheringham, Amelia K., Zhuang, Aowen, Borg, Danielle J., Flemming, Nicole B., Harvie, Ben M., Kinneally, Toni L., Yeh, Shang-Ming, McCarthy, Domenica A., Koepsell, Hermann, Vallon, Volker, Pollock, Carol, Panchapakesan, Usha and Forbes, Josephine M. (2016). Once daily administration of the SGLT2 inhibitor, empagliflozin, attenuates markers of renal fibrosis without improving albuminuria in diabetic db/db mice. Scientific Reports, 6 (1) 26428, 28124. doi: 10.1038/srep26428
2016
Journal Article
Antigen-encoding bone marrow terminates islet-directed memory CD8+ T-cell responses to alleviate islet transplant rejection
Coleman, Miranda A., Jessup, Claire F., Bridge, Jennifer A., Overgaard, Nana H., Penko, Daniella, Walters, Stacey, Borg, Danielle J., Galea, Ryan, Forbes, Josephine M., Thomas, Ranjeny, Coates, Patrick T. C., Grey, Shane T., Wells, James W. and Steptoe, Raymond J. (2016). Antigen-encoding bone marrow terminates islet-directed memory CD8+ T-cell responses to alleviate islet transplant rejection. Diabetes, 65 (5), 1328-1340. doi: 10.2337/db15-1418
2015
Conference Publication
IL-22-mediated suppression of islet inflammation
McGuckin, Mike, Hasnain, Sumaira Z., Borg, Danielle J., Loudovaris, Thomas, Kay, Thomas W., Thomas, Helen E., Whitehead, Jonathon P., Forbes, Josephine M. and Prins, John B. (2015). IL-22-mediated suppression of islet inflammation. IPITA/IXA/CTS Joint Congress, Melbourne Australia, Nov 15-19, 2015. HOBOKEN: LIPPINCOTT WILLIAMS & WILKINS.
2015
Conference Publication
Human soluble receptor for advanced glycation end products therapy reduces autoimmune diabetes in the non-obese diabetic mouse
Leung, S. S.-Y., Borg, D. J., McCarthy, D., Zhuang, A., Fotheringham, A., Di Trapani, G., Groop, P.-H., Knip, M. and Forbes, J. (2015). Human soluble receptor for advanced glycation end products therapy reduces autoimmune diabetes in the non-obese diabetic mouse. Joint Annual Conference of the International Society for Pediatric and Adolescent Diabetes and Australasian Paediatric Endocrine Group (ISPAD+APEG 2015), Brisbane, QLD Australia, 7-10 October 2015. Hoboken, NJ USA: Wiley-Blackwell Publishing. doi: 10.1111/pedi.12309
Supervision
Availability
- Dr Danielle Borg is:
- Available for supervision
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Supervision history
Current supervision
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Doctor Philosophy
The impact of the COVID-19 epidemic on infant development via changes to dietary intake and quality, mental health, and the gut microbiome of Queensland families
Associate Advisor
Other advisors: Professor Kym Rae, Associate Professor Marloes Nitert Dekker
Completed supervision
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2020
Doctor Philosophy
Novel dietary factors in diabetic and non-diabetic kidney disease
Associate Advisor
Other advisors: Honorary Professor Josephine Forbes
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2020
Doctor Philosophy
The role of receptor for advanced glycation end products (RAGE) in the development of type 1 diabetes
Associate Advisor
Other advisors: Honorary Professor Kristen Radford, Honorary Professor Josephine Forbes
Media
Enquiries
Contact Dr Danielle Borg directly for media enquiries about:
- Diabetes
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