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2025

Journal Article

The structural integrity of human TFF1 under reducing conditions

Elmaci, Dilsah Nur, Hopping, Gene, Hoffmann, Werner, Muttenthaler, Markus and Stein, Matthias (2025). The structural integrity of human TFF1 under reducing conditions. Redox Biology, 81 103534, 103534. doi: 10.1016/j.redox.2025.103534

The structural integrity of human TFF1 under reducing conditions

2024

Journal Article

Oxytocin analogues for the oral treatment of abdominal pain

Kremsmayr, Thomas, Schober, Gudrun, Kaltenböck, Matthias, Hoare, Bradley L, Brierley, Stuart M and Muttenthaler, Markus (2024). Oxytocin analogues for the oral treatment of abdominal pain. Angewandte Chemie International Edition, 63 (52) e202415333, 1-13. doi: 10.1002/anie.202415333

Oxytocin analogues for the oral treatment of abdominal pain

2024

Journal Article

Introducing… Markus Muttenthaler

Muttenthaler, Markus (2024). Introducing… Markus Muttenthaler. Angewandte Chemie-International Edition. doi: 10.1002/anie.202420694

Introducing… Markus Muttenthaler

2024

Journal Article

Oxytocin Verbindungen zur oralen Behandlung von Bauchschmerzen

Kremsmayr, Thomas, Schober, Gudrun, Kaltenböck, Matthias, Hoare, Bradley L., Brierley, Stuart M. and Muttenthaler, Markus (2024). Oxytocin Verbindungen zur oralen Behandlung von Bauchschmerzen. Angewandte Chemie, 136 (52). doi: 10.1002/ange.202415333

Oxytocin Verbindungen zur oralen Behandlung von Bauchschmerzen

2024

Book Chapter

Recent trends in peptide drug discovery and development

Madge, H. Y. R. and Muttenthaler, M. (2024). Recent trends in peptide drug discovery and development. Sustainability in tides chemistry. (pp. 23-49) edited by Alessandra Tolomelli, Lucia Ferrazzano and Walter Cabri. London, United Kingdom: Royal Society of Chemistry. doi: 10.1039/9781837674541-00023

Recent trends in peptide drug discovery and development

2024

Conference Publication

Development of gut-restricted antibiofilm peptides to target gastrointestinal biofilms

Jandl, B., Lang, M., Makristathis, A., Gasche, C. and Muttenthaler, M. (2024). Development of gut-restricted antibiofilm peptides to target gastrointestinal biofilms. HOBOKEN: The European Peptide Society. doi: 10.17952/37eps.2024.p1134

Development of gut-restricted antibiofilm peptides to target gastrointestinal biofilms

2024

Conference Publication

Chemical strategies to tune potency, selectivity and stability of venom peptides

Muttenthaler, Markus (2024). Chemical strategies to tune potency, selectivity and stability of venom peptides. IST World Congress 2024, Singapore, 20 - 25 May 2024. Oxford, United Kingdom: Elsevier. doi: 10.1016/j.toxicon.2024.108028

Chemical strategies to tune potency, selectivity and stability of venom peptides

2024

Journal Article

Novel Diacyl-hydrazide Compounds as Potential Therapeutics for Visceral Leishmaniasis

Jandl, Bernhard, Zheng, Rebecca, Muttenthaler, Markus and Baell, Jonathan (2024). Novel Diacyl-hydrazide Compounds as Potential Therapeutics for Visceral Leishmaniasis. ACS Omega, 9 (35), 37170-37182. doi: 10.1021/acsomega.4c04517

Novel Diacyl-hydrazide Compounds as Potential Therapeutics for Visceral Leishmaniasis

2024

Conference Publication

Development of an equipotent NaV1.1 and NaV1.7 inhibitor for the treatment of chronic visceral pain

Eagles, David, King, Glenn, Cardoso, Fernanda, Muttenthaler, Markus and Brierley, Stuart (2024). Development of an equipotent NaV1.1 and NaV1.7 inhibitor for the treatment of chronic visceral pain. 37th European Peptide Symposium 14th International Peptide Symposium, Florence, Italy, 25 - 29 August 2024. Hoboken, NJ, United States: Wiley.

Development of an equipotent NaV1.1 and NaV1.7 inhibitor for the treatment of chronic visceral pain

2024

Journal Article

Intestinal biofilms: pathophysiological relevance, host defense, and therapeutic opportunities

Jandl, Bernhard, Dighe, Satish, Gasche, Christoph, Makristathis, Athanasios and Muttenthaler, Markus (2024). Intestinal biofilms: pathophysiological relevance, host defense, and therapeutic opportunities. Clinical Microbiology Reviews, 37 (3) e0013323, e0013323. doi: 10.1128/cmr.00133-23

Intestinal biofilms: pathophysiological relevance, host defense, and therapeutic opportunities

2024

Journal Article

Gastrointestinal biofilms – Endoscopic detection, disease relevance and therapeutic strategies

Jandl, Bernhard, Dighe, Satish, Baumgartner, Maximillian, Makristathis, Athanasios, Gasche, Christoph and Muttenthaler, Markus (2024). Gastrointestinal biofilms – Endoscopic detection, disease relevance and therapeutic strategies. Gastroenterology, 167 (6), 1098-1112. doi: 10.1053/j.gastro.2024.04.032

Gastrointestinal biofilms – Endoscopic detection, disease relevance and therapeutic strategies

2024

Journal Article

Oxytocin and vasopressin signaling in health and disease

Perisic, Monika, Woolcock, Katrina, Hering, Anke, Mendel, Helen and Muttenthaler, Markus (2024). Oxytocin and vasopressin signaling in health and disease. Trends in Biochemical Sciences, 49 (4), 361-377. doi: 10.1016/j.tibs.2024.01.010

Oxytocin and vasopressin signaling in health and disease

2024

Journal Article

Targeting the oxytocin receptor for breast cancer management: a niche for peptide tracers

Kalaba, Predrag, Sanchez de la Rosa, Cristina, Möller, Andreas, Alewood, Paul F. and Muttenthaler, Markus (2024). Targeting the oxytocin receptor for breast cancer management: a niche for peptide tracers. Journal of Medicinal Chemistry, 67 (3), 1625-1640. doi: 10.1021/acs.jmedchem.3c01089

Targeting the oxytocin receptor for breast cancer management: a niche for peptide tracers

2024

Journal Article

Archaea influence composition of endoscopically visible ileocolonic biofilms

Orgler, Elisabeth, Baumgartner, Maximilian, Duller, Stefanie, Kumptisch, Christina, Hausmann, Bela, Moser, Doris, Khare, Vineeta, Lang, Michaela, Köcher, Thomas, Frick, Adrian, Muttenthaler, Markus, Makristathis, Athanasios, Moissl-Eichinger, Christine and Gasche, Christoph (2024). Archaea influence composition of endoscopically visible ileocolonic biofilms. Gut Microbes, 16 (1) 2359500. doi: 10.1080/19490976.2024.2359500

Archaea influence composition of endoscopically visible ileocolonic biofilms

2023

Journal Article

Design and structural validation of peptide–drug conjugate ligands of the kappa-opioid receptor

Muratspahić, Edin, Deibler, Kristine, Han, Jianming, Tomašević, Nataša, Jadhav, Kirtikumar B., Olivé-Marti, Aina-Leonor, Hochrainer, Nadine, Hellinger, Roland, Koehbach, Johannes, Fay, Jonathan F., Rahman, Mohammad Homaidur, Hegazy, Lamees, Craven, Timothy W., Varga, Balazs R., Bhardwaj, Gaurav, Appourchaux, Kevin, Majumdar, Susruta, Muttenthaler, Markus, Hosseinzadeh, Parisa, Craik, David J., Spetea, Mariana, Che, Tao, Baker, David and Gruber, Christian W. (2023). Design and structural validation of peptide–drug conjugate ligands of the kappa-opioid receptor. Nature Communications, 14 (1) 8064, 1-17. doi: 10.1038/s41467-023-43718-w

Design and structural validation of peptide–drug conjugate ligands of the kappa-opioid receptor

2023

Journal Article

Photoswitchable probes of oxytocin and vasopressin

Wirth, Ulrike, Raabe, Konstantin, Kalaba, Predrag, Keimpema, Erik, Muttenthaler, Markus and König, Burkhard (2023). Photoswitchable probes of oxytocin and vasopressin. Journal of Medicinal Chemistry, 66 (21), 14853-14865. doi: 10.1021/acs.jmedchem.3c01415

Photoswitchable probes of oxytocin and vasopressin

2023

Conference Publication

Development and application of fluorescent oxytocin receptor tracers

Perisic, Ms Monika, Kalaba, Predrag, Keimpema, Erik, Muttenthaler, Markus and Gruber, Christian (2023). Development and application of fluorescent oxytocin receptor tracers. 19th World Congress of Basic and Clinical Pharmacology (WCP), Glasgow Scotland, Jul 02-07, 2023. HOBOKEN: WILEY.

Development and application of fluorescent oxytocin receptor tracers

2022

Journal Article

Expanding the versatility and scope of the oxime ligation: rapid bioconjugation to disulfide-rich peptides

Hering, Anke, Braga Emidio, Nayara and Muttenthaler, Markus (2022). Expanding the versatility and scope of the oxime ligation: rapid bioconjugation to disulfide-rich peptides. Chemical Communications, 58 (65), 9100-9103. doi: 10.1039/d2cc03752a

Expanding the versatility and scope of the oxime ligation: rapid bioconjugation to disulfide-rich peptides

2022

Journal Article

High oxytocin receptor expression linked to increased cell migration and reduced survival in patients with triple-negative breast cancer

Liu, Huiping and Muttenthaler, Markus (2022). High oxytocin receptor expression linked to increased cell migration and reduced survival in patients with triple-negative breast cancer. Biomedicines, 10 (7) 1595, 1-20. doi: 10.3390/biomedicines10071595

High oxytocin receptor expression linked to increased cell migration and reduced survival in patients with triple-negative breast cancer

2022

Journal Article

Approaches to improve the quantitation of oxytocin in human serum by mass spectrometry

Hering, Anke, Jieu, Beverly, Jones, Alun and Muttenthaler, Markus (2022). Approaches to improve the quantitation of oxytocin in human serum by mass spectrometry. Frontiers in Chemistry, 10 889154, 1-11. doi: 10.3389/fchem.2022.889154

Approaches to improve the quantitation of oxytocin in human serum by mass spectrometry