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2010

Journal Article

Ligand-based peptide design and combinatorial peptide libraries to target G protein-coupled receptors

Gruber, Christian W., Muttenthaler, Markus and Freissmuth, Michael (2010). Ligand-based peptide design and combinatorial peptide libraries to target G protein-coupled receptors. Current Pharmaceutical Design, 16 (28), 3071-3088. doi: 10.2174/138161210793292474

Ligand-based peptide design and combinatorial peptide libraries to target G protein-coupled receptors

2010

Journal Article

α-Conotoxin AuIB isomers exhibit distinct inhibitory mechanisms and differential sensitivity to stoichiometry of α3β4 nicotinic acetylcholine receptors

Grishin, Anton, Wang, Ching-I. A., Muttenthaler, Markus, Alewood, Paul F., Lewis, Richard J. and Adams, David J. (2010). α-Conotoxin AuIB isomers exhibit distinct inhibitory mechanisms and differential sensitivity to stoichiometry of α3β4 nicotinic acetylcholine receptors. Journal of Biological Chemistry, 285 (29), 22254-22263. doi: 10.1074/jbc.M110.111880

α-Conotoxin AuIB isomers exhibit distinct inhibitory mechanisms and differential sensitivity to stoichiometry of α3β4 nicotinic acetylcholine receptors

2010

Journal Article

Solving the alpha-conotoxin folding problem: Efficient selenium-directed on-resin generation of more potent and stable nicotinic acetylcholine receptor antaqonists

Muttenthaler, Marcus, Nevin, Simon T., Grishin, Anton A., Ngo, Shyuan T., Choy, Peng T., Daly, Norelle L., Hu, Shu-Hong, Armishaw, Christopher J., Wang, Ching-I. A., Lewis, Richard J., Martin, Jennifer L., Noakes, Peter G., Craik, David J., Adams, David J. and Alewood, Paul F. (2010). Solving the alpha-conotoxin folding problem: Efficient selenium-directed on-resin generation of more potent and stable nicotinic acetylcholine receptor antaqonists. Journal of the American Chemical Society, 132 (10), 3514-3522. doi: 10.1021/ja910602h

Solving the alpha-conotoxin folding problem: Efficient selenium-directed on-resin generation of more potent and stable nicotinic acetylcholine receptor antaqonists

2010

Journal Article

p-Nitrobenzyl protection for cysteine and selenocysteine: A more stable alternative to the acetamidomethyl group

Muttenthaler, Markus, Ramos, Yesica Garcia, Feytens, Debby, Dantas de Araujo, Aline and Alewood, Paul F. (2010). p-Nitrobenzyl protection for cysteine and selenocysteine: A more stable alternative to the acetamidomethyl group. Biopolymers, 94 (4), 423-432. doi: 10.1002/bip.21502

p-Nitrobenzyl protection for cysteine and selenocysteine: A more stable alternative to the acetamidomethyl group

2010

Conference Publication

Oxytocin agonist design - A selenocysteine mimetic reveals a functional selectivity switch for the human oxytocin receptor

Muttenthaler, M. M., de Araujo, A. D., Andersson, A., Vetter, I., Gruber, C., Ramos, Y. Garcia, Feytens, D., Bergmayr, C., Freissmuth, M., Lewis, R. and Alewood, P. (2010). Oxytocin agonist design - A selenocysteine mimetic reveals a functional selectivity switch for the human oxytocin receptor. 31st European Peptide Symposium, Copenhagen, Denmark, 5-9 September 2010. Chichester, West Sussex, U.K.: John Wiley & Sons. doi: 10.1002/psc.1303

Oxytocin agonist design - A selenocysteine mimetic reveals a functional selectivity switch for the human oxytocin receptor

2009

Other Outputs

Peptide engineering - controlling the folding of disulfide-rich peptides

Muttenthaler, Markus (2009). Peptide engineering - controlling the folding of disulfide-rich peptides. PhD Thesis, Institute for Molecular Bioscience, The University of Queensland.

Peptide engineering - controlling the folding of disulfide-rich peptides

2009

Book Chapter

Selenocystine peptides - synthesis, folding and applications

Muttenthaler, M. and Alewood, P. F. (2009). Selenocystine peptides - synthesis, folding and applications. Oxidative folding of peptides and proteins. (pp. 396-418) edited by Johannes Buchner. Cambridge , U.K.: Royal Society of Chemistry. doi: 10.1039/9781847559265-00396

Selenocystine peptides - synthesis, folding and applications

2008

Journal Article

Selenopeptide chemistry

Muttenthaler, Markus and Alewood, Paul F. (2008). Selenopeptide chemistry. Journal of Peptide Science, 14 (12), 1223-1239. doi: 10.1002/psc.1075

Selenopeptide chemistry

2008

Journal Article

Conopressin-T from Conus tulipa reveals an antagonist switch in vasopressin-like peptide

Dutertre, Sébastien, Croker, Daniel, Daly, Norelle L., Andersson, Åsa, Muttenthaler, Markus, Lumsden, Natalie G., Craik, David J., Alewood, Paul F., Guillon, Gilles and Lewis, Richard J. (2008). Conopressin-T from Conus tulipa reveals an antagonist switch in vasopressin-like peptide. Journal of Biological Chemistry, 283 (11), 7100-7108. doi: 10.1074/jbc.M706477200

Conopressin-T from Conus tulipa reveals an antagonist switch in vasopressin-like peptide

2008

Conference Publication

Selenocysteine in peptide drug design

Adams, D. J., Alewood, P. F., Choy, P. T., Craik, D. J., Daly, N. L., Grishin, A. A., Hu, S-H., Martin, J. L., Muttenthaler, M., Nevin, S. T., Ngo, S. T. and Noakes, P. G. (2008). Selenocysteine in peptide drug design. Royal Australian Chemical Institute (RACI) Annual Scientific Meeting: Drug Discovery and Development, Couran Cove Island Resort, Queensland, Australia, 13 - 17 July 2008.

Selenocysteine in peptide drug design

2008

Conference Publication

Selenocysteine in peptide folding and drug design

Muttenthaler, M., Nevin, S. T., Grishin, A. A., Ngo, S. T., Choy, P. T., Daly, N. L., Hu, S-H., Martin, J. L., Noakes, P. G., Craik, D. J., Adams, D. J. and Alewood, P. F. (2008). Selenocysteine in peptide folding and drug design. XXth International Symposium on Medicinal Chemistry (EFMC-ISMC 2008), Vienna, Austria, 31 August - 4 September 2008.

Selenocysteine in peptide folding and drug design

2006

Conference Publication

Directed folding of alpha-conotoxins using selenocysteine

Muttenthaler, M. and Alewood, P. F. (2006). Directed folding of alpha-conotoxins using selenocysteine. 29th European Peptide Symposium, Gdansk, Poland, 3-8 September 2006. Chichester, U.K.: John Wiley & Sons. doi: 10.1002/psc.796

Directed folding of alpha-conotoxins using selenocysteine

2005

Journal Article

Synthesis and characterisation of new ditetrazole-ligands as more rigid building blocks of envisaged iron(II) spin-crossover coordination polymers

Muttenthaler M., Bartel M., Weinberger P., Hilscher G. and Linert W. (2005). Synthesis and characterisation of new ditetrazole-ligands as more rigid building blocks of envisaged iron(II) spin-crossover coordination polymers. Journal of Molecular Structure, 741 (1-3), 159-169. doi: 10.1016/j.molstruc.2005.02.007

Synthesis and characterisation of new ditetrazole-ligands as more rigid building blocks of envisaged iron(II) spin-crossover coordination polymers