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2020 Journal Article Chemical synthesis of human trefoil factor 1 (TFF1) and its homodimer provides novel insights into their mechanisms of actionBraga Emidio, Nayara, Baik, Hayeon, Lee, David, Stürmer, René, Heuer, Jörn, Elliott, Alysha G., Blaskovich, Mark A. T., Haupenthal, Katharina, Tegtmeyer, Nicole, Hoffmann, Werner, Schroeder, Christina I. and Muttenthaler, Markus (2020). Chemical synthesis of human trefoil factor 1 (TFF1) and its homodimer provides novel insights into their mechanisms of action. Chemical Communications, 56 (47), 6420-6423. doi: 10.1039/d0cc02321c |
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2020 Book Chapter Anhydrous hydrogen fluoride cleavage in boc solid phase peptide synthesisJadhav, Kirtikumar B, Woolcock, Katrina J and Muttenthaler, Markus (2020). Anhydrous hydrogen fluoride cleavage in boc solid phase peptide synthesis. Peptide Synthesis. (pp. 41-57) edited by Waleed M. Hussein, Mariusz Skwarczynski and Istvan Toth. New York, NY, United States: Humana. doi: 10.1007/978-1-0716-0227-0_4 |
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2019 Journal Article I8-arachnotocin–an arthropod-derived G protein-biased ligand of the human vasopressin V2 receptorDuerrauer, Leopold, Muratspahić, Edin, Gattringer, Jasmin, Keov, Peter, Mendel, Helen C., Pfleger, Kevin D. G., Muttenthaler, Markus and Gruber, Christian W. (2019). I8-arachnotocin–an arthropod-derived G protein-biased ligand of the human vasopressin V2 receptor. Scientific Reports, 9 (1) 19295, 19295. doi: 10.1038/s41598-019-55675-w |
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2019 Journal Article Conotoxins: chemistry and biologyJin, Ai-Hua, Muttenthaler, Markus, Dutertre, Sebastien, Himaya, S.W.A., Kaas, Quentin, Craik, David J., Lewis, Richard J. and Alewood, Paul F. (2019). Conotoxins: chemistry and biology. Chemical Reviews, 119 (21), 11510-11549. doi: 10.1021/acs.chemrev.9b00207 |
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2019 Journal Article Trefoil Factor Family: Unresolved Questions and Clinical PerspectivesBraga Emidio, Nayara, Hoffmann, Werner, Brierley, Stuart M. and Muttenthaler, Markus (2019). Trefoil Factor Family: Unresolved Questions and Clinical Perspectives. Trends in Biochemical Sciences, 44 (5), 387-390. doi: 10.1016/j.tibs.2019.01.004 |
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2019 Journal Article On-resin strategy to label α-Conotoxins: Cy5-RgIA, a potent α9α10 nicotinic acetylcholine receptor imaging probeMuttenthaler, Markus, Nevin, Simon T., Inserra, Marco, Lewis, Richard J., Adams, David J. and Alewood, Paul F. (2019). On-resin strategy to label α-Conotoxins: Cy5-RgIA, a potent α9α10 nicotinic acetylcholine receptor imaging probe. Australian Journal of Chemistry, 73 (4), 327-333. doi: 10.1071/CH19456 |
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2019 Other Outputs Use of single dendritic wedge cell penetrating peptides to facilitate cellular delivery of nanoparticles and nanoparticles carrying cargosMuttenthaler, M., Breger, J.C., Delehanty, J.B., Ricks-Laskoski, H., Dawson, P.E. and Medintz, I.L. (2019). Use of single dendritic wedge cell penetrating peptides to facilitate cellular delivery of nanoparticles and nanoparticles carrying cargos. US10183080B2. |
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2019 Other Outputs Novel oxytocin analoguesMuttenthaler, M., Hering, A., Pascali, G. and Guastella, A. (2019). Novel oxytocin analogues. 1002581997. |
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2018 Journal Article Oxytocin-like signaling in ants influences metabolic gene expression and locomotor activityLiutkevičiūtė, Zita, Gil-Mansilla, Esther, Eder, Thomas, Casillas-Pérez, Barbara, Di Giglio, Maria Giulia, Muratspahić, Edin, Grebien, Florian, Rattei, Thomas, Muttenthaler, Markus, Cremer, Sylvia and Gruber, Christian W. (2018). Oxytocin-like signaling in ants influences metabolic gene expression and locomotor activity. The FASEB Journal, 32 (12), 6808-6821. doi: 10.1096/fj.201800443 |
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2018 Journal Article Evaluation of Chemical Strategies for Improving the Stability and Oral Toxicity of Insecticidal PeptidesHerzig, Volker, de Araujo, Aline, Greenwood, Kathryn, Chin, Yanni, Windley, Monique, Chong, Youmie, Muttenthaler, Markus, Mobli, Mehdi, Audsley, Neil, Nicholson, Graham, Alewood, Paul and King, Glenn (2018). Evaluation of Chemical Strategies for Improving the Stability and Oral Toxicity of Insecticidal Peptides. Biomedicines, 6 (3) 90, 90. doi: 10.3390/biomedicines6030090 |
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2018 Conference Publication Advancing the frontiers of chemical protein synthesis - the 7CPS meeting, Haifa, IsraelConibear, Anne C. and Muttenthaler, Markus (2018). Advancing the frontiers of chemical protein synthesis - the 7CPS meeting, Haifa, Israel. Cambridge, MA, United States: Cell Press. doi: 10.1016/j.chembiol.2018.03.001 |
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2018 Journal Article Contractility measurements of human uterine smooth muscle to aid drug developmentArrowsmith, Sarah, Keov, Peter, Muttenthaler, Markus and Gruber, Christian W. (2018). Contractility measurements of human uterine smooth muscle to aid drug development. Journal of Visualized Experiments, 2018 (131) e56639. doi: 10.3791/56639 |
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2017 Journal Article Subtle modifications to oxytocin produce ligands that retain potency and improved selectivity across speciesMuttenthaler, Markus, Andersson, Asa, Vetter, Irina, Menon, Rohit, Busnelli, Marta, Ragnarsson, Lotten, Bergmayr, Christian, Arrowsmith, Sarah, Deuis, Jennifer R., Chiu, Han Sheng, Palpant, Nathan J., O'Brien, Margaret, Smith, Terry J., Wray, Susan, Neumann, Inga D., Gruber, Christian W., Lewis, Richard J. and Alewood, Paul F. (2017). Subtle modifications to oxytocin produce ligands that retain potency and improved selectivity across species. Science Signaling, 10 (508) eaan3398, 1-13. doi: 10.1126/scisignal.aan3398 |
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2017 Journal Article Nanoparticle cellular uptake by dendritic wedge peptides: achieving single peptide facilitated deliveryBreger, Joyce C., Muttenthaler, Markus, Delehanty, James B., Thompson, Darren A., Oh, Eunkeu, Susumu, Kimihiro, Deschamps, Jeffrey R., Anderson, George P., Field, Lauren D., Walper, Scott A., Dawson, Philip E. and Medintz, Igor L. (2017). Nanoparticle cellular uptake by dendritic wedge peptides: achieving single peptide facilitated delivery. Nanoscale, 9 (29), 10447-10464. doi: 10.1039/c7nr03362a |
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2017 Journal Article Synthesis of multivalent [Lys8]-oxytocin dendrimers that inhibit visceral nociceptive responsesWan, Jingjing, Mobli, Mehdi, Brust, Andreas, Muttenthaler, Markus, Andersson, Asa, Ragnarsson, Lotten, Castro, Joel, Vetter, Irina, Huang, Johnny X., Nilsson, Mathias, Brierley, Stuart M., Cooper, Matthew A., Lewis, Richard J. and Alewood, Paul F. (2017). Synthesis of multivalent [Lys8]-oxytocin dendrimers that inhibit visceral nociceptive responses. Australian Journal of Chemistry, 70 (2), 162-171. doi: 10.1071/CH16407 |
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2017 Journal Article Development of a human vasopressin V1a-receptor antagonist from an evolutionary-related insect neuropeptideDi Giglio, Maria Giulia , Muttenthaler, Markus, Harpsoe, Kasper, Liutkeviciute, Zita, Keov, Peter, Eder, Thomas, Rattei, Thomas, Arrowsmith, Sarah, Wray, Susan, Marek, Ales, Elbert, Tomas, Alewood, Paul F. , Gloriam, David E. and Gruber, Christian W. (2017). Development of a human vasopressin V1a-receptor antagonist from an evolutionary-related insect neuropeptide. Scientific Reports, 7 (1) 41002, 41002. doi: 10.1038/srep41002 |
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2016 Conference Publication Pharmacological Probes for Oxytocin/vasopressin Gpcr Subtypes Based On In-Vertebrate Peptide HomologsDi Giglio, M. G., Muttenthaler, M. and Gruber, C. W. (2016). Pharmacological Probes for Oxytocin/vasopressin Gpcr Subtypes Based On In-Vertebrate Peptide Homologs. HOBOKEN: WILEY. |
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2016 Journal Article Design and characterization of superpotent bivalent ligands targeting oxytocin receptor dimers via a channel-like structureBusnelli, Marta, Kleinau, Gunnar, Muttenthaler, Markus, Stoev, Stoytcho, Manning, Maurice, Bibic, Lucka, Howell, Lesley A., McCormick, Peter J., Di Lascio, Simona, Braida, Daniela, Sala, Mariaelvina, Rovati, G. Enrico, Bellini, Tommaso and Chini, Bice (2016). Design and characterization of superpotent bivalent ligands targeting oxytocin receptor dimers via a channel-like structure. Journal of Medicinal Chemistry, 59 (15), 7152-7166. doi: 10.1021/acs.jmedchem.6b00564 |
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2016 Conference Publication Expression and function of vasopressin receptor subtypes in human myometrium: implications for effective tocolysisArrowsmith, Sarah, Taylor, Olayisade, Muttenthaler, Markus and Wray, Susan (2016). Expression and function of vasopressin receptor subtypes in human myometrium: implications for effective tocolysis. HOBOKEN: WILEY-BLACKWELL. |
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2016 Conference Publication Miklos Bodanszky Award Lecture Probing the Functional Complexity of Ancient Oxytocin in Health and DiseaseMuttenthaler, Markus, Andersson, Asa, Ragnarsson, Lotten, Vetter, Irina, Busnelli, Marta, Chini, Bice, Arrowsmith, Sarah, Wray, Susan, de Araujo, Aline Dantas, Dutertre, Sebastien, Mobli, Mehdi, Lewis, Richard J., Gruber, Christian W. and Alewood, Paul F. (2016). Miklos Bodanszky Award Lecture Probing the Functional Complexity of Ancient Oxytocin in Health and Disease. 34th European Peptide Symposium, Leipzig, Germany, 4‐9 September 2016. Hoboken, NJ United States: Wiley. |
