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2025 Journal Article The structural integrity of human TFF1 under reducing conditionsElmaci, Dilsah Nur, Hopping, Gene, Hoffmann, Werner, Muttenthaler, Markus and Stein, Matthias (2025). The structural integrity of human TFF1 under reducing conditions. Redox Biology, 81 103534, 103534. doi: 10.1016/j.redox.2025.103534 |
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2024 Journal Article Oxytocin analogues for the oral treatment of abdominal painKremsmayr, Thomas, Schober, Gudrun, Kaltenböck, Matthias, Hoare, Bradley L, Brierley, Stuart M and Muttenthaler, Markus (2024). Oxytocin analogues for the oral treatment of abdominal pain. Angewandte Chemie International Edition, 63 (52) e202415333, 1-13. doi: 10.1002/anie.202415333 |
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2024 Journal Article Introducing… Markus MuttenthalerMuttenthaler, Markus (2024). Introducing… Markus Muttenthaler. Angewandte Chemie-International Edition. doi: 10.1002/anie.202420694 |
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2024 Journal Article Oxytocin Verbindungen zur oralen Behandlung von BauchschmerzenKremsmayr, Thomas, Schober, Gudrun, Kaltenböck, Matthias, Hoare, Bradley L., Brierley, Stuart M. and Muttenthaler, Markus (2024). Oxytocin Verbindungen zur oralen Behandlung von Bauchschmerzen. Angewandte Chemie, 136 (52). doi: 10.1002/ange.202415333 |
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2024 Journal Article Novel Diacyl-hydrazide Compounds as Potential Therapeutics for Visceral LeishmaniasisJandl, Bernhard, Zheng, Rebecca, Muttenthaler, Markus and Baell, Jonathan (2024). Novel Diacyl-hydrazide Compounds as Potential Therapeutics for Visceral Leishmaniasis. ACS Omega, 9 (35), 37170-37182. doi: 10.1021/acsomega.4c04517 |
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2024 Journal Article Intestinal biofilms: pathophysiological relevance, host defense, and therapeutic opportunitiesJandl, Bernhard, Dighe, Satish, Gasche, Christoph, Makristathis, Athanasios and Muttenthaler, Markus (2024). Intestinal biofilms: pathophysiological relevance, host defense, and therapeutic opportunities. Clinical Microbiology Reviews, 37 (3) e0013323, e0013323. doi: 10.1128/cmr.00133-23 |
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2024 Journal Article Gastrointestinal biofilms – Endoscopic detection, disease relevance and therapeutic strategiesJandl, Bernhard, Dighe, Satish, Baumgartner, Maximillian, Makristathis, Athanasios, Gasche, Christoph and Muttenthaler, Markus (2024). Gastrointestinal biofilms – Endoscopic detection, disease relevance and therapeutic strategies. Gastroenterology, 167 (6), 1098-1112. doi: 10.1053/j.gastro.2024.04.032 |
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2024 Journal Article Oxytocin and vasopressin signaling in health and diseasePerisic, Monika, Woolcock, Katrina, Hering, Anke, Mendel, Helen and Muttenthaler, Markus (2024). Oxytocin and vasopressin signaling in health and disease. Trends in Biochemical Sciences, 49 (4), 361-377. doi: 10.1016/j.tibs.2024.01.010 |
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2024 Journal Article Targeting the oxytocin receptor for breast cancer management: a niche for peptide tracersKalaba, Predrag, Sanchez de la Rosa, Cristina, Möller, Andreas, Alewood, Paul F. and Muttenthaler, Markus (2024). Targeting the oxytocin receptor for breast cancer management: a niche for peptide tracers. Journal of Medicinal Chemistry, 67 (3), 1625-1640. doi: 10.1021/acs.jmedchem.3c01089 |
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2024 Journal Article Archaea influence composition of endoscopically visible ileocolonic biofilmsOrgler, Elisabeth, Baumgartner, Maximilian, Duller, Stefanie, Kumptisch, Christina, Hausmann, Bela, Moser, Doris, Khare, Vineeta, Lang, Michaela, Köcher, Thomas, Frick, Adrian, Muttenthaler, Markus, Makristathis, Athanasios, Moissl-Eichinger, Christine and Gasche, Christoph (2024). Archaea influence composition of endoscopically visible ileocolonic biofilms. Gut Microbes, 16 (1) 2359500. doi: 10.1080/19490976.2024.2359500 |
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2023 Journal Article Design and structural validation of peptide–drug conjugate ligands of the kappa-opioid receptorMuratspahić, Edin, Deibler, Kristine, Han, Jianming, Tomašević, Nataša, Jadhav, Kirtikumar B., Olivé-Marti, Aina-Leonor, Hochrainer, Nadine, Hellinger, Roland, Koehbach, Johannes, Fay, Jonathan F., Rahman, Mohammad Homaidur, Hegazy, Lamees, Craven, Timothy W., Varga, Balazs R., Bhardwaj, Gaurav, Appourchaux, Kevin, Majumdar, Susruta, Muttenthaler, Markus, Hosseinzadeh, Parisa, Craik, David J., Spetea, Mariana, Che, Tao, Baker, David and Gruber, Christian W. (2023). Design and structural validation of peptide–drug conjugate ligands of the kappa-opioid receptor. Nature Communications, 14 (1) 8064, 1-17. doi: 10.1038/s41467-023-43718-w |
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2023 Journal Article Photoswitchable probes of oxytocin and vasopressinWirth, Ulrike, Raabe, Konstantin, Kalaba, Predrag, Keimpema, Erik, Muttenthaler, Markus and König, Burkhard (2023). Photoswitchable probes of oxytocin and vasopressin. Journal of Medicinal Chemistry, 66 (21), 14853-14865. doi: 10.1021/acs.jmedchem.3c01415 |
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2022 Journal Article Expanding the versatility and scope of the oxime ligation: rapid bioconjugation to disulfide-rich peptidesHering, Anke, Braga Emidio, Nayara and Muttenthaler, Markus (2022). Expanding the versatility and scope of the oxime ligation: rapid bioconjugation to disulfide-rich peptides. Chemical Communications, 58 (65), 9100-9103. doi: 10.1039/d2cc03752a |
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2022 Journal Article High oxytocin receptor expression linked to increased cell migration and reduced survival in patients with triple-negative breast cancerLiu, Huiping and Muttenthaler, Markus (2022). High oxytocin receptor expression linked to increased cell migration and reduced survival in patients with triple-negative breast cancer. Biomedicines, 10 (7) 1595, 1-20. doi: 10.3390/biomedicines10071595 |
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2022 Journal Article Approaches to improve the quantitation of oxytocin in human serum by mass spectrometryHering, Anke, Jieu, Beverly, Jones, Alun and Muttenthaler, Markus (2022). Approaches to improve the quantitation of oxytocin in human serum by mass spectrometry. Frontiers in Chemistry, 10 889154, 1-11. doi: 10.3389/fchem.2022.889154 |
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2022 Journal Article On the utility of chemical strategies to improve peptide gut stabilityKremsmayr, Thomas, Aljnabi, Aws, Blanco-Canosa, Juan B., Tran, Hue N. T., Emidio, Nayara Braga and Muttenthaler, Markus (2022). On the utility of chemical strategies to improve peptide gut stability. Journal of Medicinal Chemistry, 65 (8), 6191-6206. doi: 10.1021/acs.jmedchem.2c00094 |
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2021 Journal Article Mucosal biofilms are an endoscopic feature of irritable bowel syndrome and ulcerative colitisBaumgartner, Maximilian, Lang, Michaela, Holley, Hunter, Crepaz, Daniel, Hausmann, Bela, Pjevac, Petra, Moser, Doris, Haller, Felix, Hof, Fabian, Beer, Andrea, Orgler, Elisabeth, Frick, Adrian, Khare, Vineeta, Evstatiev, Rayko, Strohmaier, Susanne, Primas, Christian, Dolak, Werner, Köcher, Thomas, Klavins, Kristaps, Rath, Timo, Neurath, Markus F., Berry, David, Makristathis, Athanasios, Muttenthaler, Markus and Gasche, Christoph (2021). Mucosal biofilms are an endoscopic feature of irritable bowel syndrome and ulcerative colitis. Gastroenterology, 161 (4), 1245-1256.e20. doi: 10.1053/j.gastro.2021.06.024 |
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2021 Journal Article Chemical synthesis of TFF3 reveals novel mechanistic insights and a gut-stable metaboliteBraga Emidio, Nayara, Meli, Rajeshwari, Tran, Hue N. T., Baik, Hayeon, Morisset-Lopez, Séverine, Elliott, Alysha G., Blaskovich, Mark A. T., Spiller, Sabrina, Beck-Sickinger, Annette G., Schroeder, Christina I. and Muttenthaler, Markus (2021). Chemical synthesis of TFF3 reveals novel mechanistic insights and a gut-stable metabolite. Journal of Medicinal Chemistry, 64 (13) acs.jmedchem.1c00767, 9484-9495. doi: 10.1021/acs.jmedchem.1c00767 |
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2021 Journal Article Improving the gastrointestinal stability of linaclotideBraga Emidio, Nayara, Tran, Hue N. T., Andersson, Asa, Dawson, Philip E., Albericio, Fernando, Vetter, Irina and Muttenthaler, Markus (2021). Improving the gastrointestinal stability of linaclotide. Journal of Medicinal Chemistry, 64 (12) acs.jmedchem.1c00380, 8384-8390. doi: 10.1021/acs.jmedchem.1c00380 |
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2021 Journal Article Trends in peptide drug discoveryMuttenthaler, Markus, King, Glenn F., Adams, David J. and Alewood, Paul F. (2021). Trends in peptide drug discovery. Nature Reviews Drug Discovery, 20 (4), 309-325. doi: 10.1038/s41573-020-00135-8 |
