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2005 Journal Article Functional genomics meets neurodegenerative disorders: part I: transcriptomic and proteomic technologyDavid, Della C., Hoerndli, Frederic and Gotz, Juergen (2005). Functional genomics meets neurodegenerative disorders: part I: transcriptomic and proteomic technology. Progress in Neurobiology, 76 (3), 153-168. doi: 10.1016/j.pneurobio.2005.07.001 |
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2005 Journal Article Role of the protein tau in Alzheimer's diseaseGötz, Jürgen, Ittner, Lars M. and David, Della C. (2005). Role of the protein tau in Alzheimer's disease. Drug Discovery Today: Disease Mechanisms, 2 (4), 395-400. doi: 10.1016/j.ddmec.2005.11.008 |
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2004 Journal Article Reference genes identified in SH-SY5Y cells using custom-made gene arrays with validation by quantitative polymerase chain reactionHoerndli, Frédéric J., Toigo, Marco, Schild, Andreas, Gotz, Jürgen and Day, Philip J. (2004). Reference genes identified in SH-SY5Y cells using custom-made gene arrays with validation by quantitative polymerase chain reaction. Analytical Biochemistry, 335 (1), 30-41. doi: 10.1016/j.ab.2004.08.028 |
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2004 Journal Article Amyloid-induced neurofibrillary tangle formation in Alzheimer's disease: insight from transgenic mouse and tissue-culture modelsGotz, Juergen, Schild, Andreas, Hoerndli, Fred and Pennanen, Luis (2004). Amyloid-induced neurofibrillary tangle formation in Alzheimer's disease: insight from transgenic mouse and tissue-culture models. International Journal of Developmental Neuroscience, 22 (7), 453-465. doi: 10.1016/j.ijdevneu.2004.07.013 |
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2004 Journal Article Transgenic animal models of Alzheimer's disease and related disorders: Histopathology, behavior and therapyGotz, J, Streffer, JR, David, D, Schild, A, Hoerndli, F, Pennanen, L, Kurosinski, P and Chen, F (2004). Transgenic animal models of Alzheimer's disease and related disorders: Histopathology, behavior and therapy. Molecular Psychiatry, 9 (7), 664-683. doi: 10.1038/sj.mp.4001508 |
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2004 Journal Article Role for glyoxalase I in Alzheimer's diseaseChen, Feng, Wollmer, M. Axel, Hoerndli, Frederic, Munch, Gerald, Kuhla, Bjorn, Rogaev, Evgeny I., Tsolaki, Magdalini, Papassotiropoulos, Andreas and Gotz, Juergen (2004). Role for glyoxalase I in Alzheimer's disease. National Academy of Sciences. Proceedings, 101 (20), 7687-7692. doi: 10.1073/pnas.0402338101 |
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2004 Journal Article Accelerated extinction of conditioned taste aversion in P301L tau transgenic micePennanen, Luis, Welzl, Hans, D'Adamo, Patrizia, Nitsch, Roger M. and Gotz, Juergen (2004). Accelerated extinction of conditioned taste aversion in P301L tau transgenic mice. Neurobiology of Disease, 15 (3), 500-509. doi: 10.1016/j.nbd.2003.11.020 |
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2004 Journal Article Genomic organisation, chromosomal localisation tissue distribution and developmental regulation of the PR61/B′ regulatory subunits of protein phosphatase 2A in miceMartens, Ellen, Stevens, Ilse, Janssens, Veerle, Vermeesch, Joris, Gotz, Juergen, Goris, Jozef and Van Hoof , Christine Van (2004). Genomic organisation, chromosomal localisation tissue distribution and developmental regulation of the PR61/B′ regulatory subunits of protein phosphatase 2A in mice. Journal of Molecular Biology, 336 (4), 971-986. doi: 10.1016/j.jmb.2003.12.047 |
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2004 Journal Article Transgenic Mice Expressing the Nucleoprotein of Borna Disease Virus in either Neurons or Astrocytes: Decreased Susceptibility to Homotypic Infection and DiseaseRauer, Mathias, Gotz, Jurgen, Schuppli, Daniel, Staeheli, Peter and Hausmann, Jurgen (2004). Transgenic Mice Expressing the Nucleoprotein of Borna Disease Virus in either Neurons or Astrocytes: Decreased Susceptibility to Homotypic Infection and Disease. Journal of Virology, 78 (7), 3621-3632. doi: 10.1128/JVI.78.7.3621-3632.2004 |
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2004 Journal Article Posttranslational modifications of tau - Role in human tauopathies and modeling in transgenic animalsChen F., David D., Ferrari A. and Gotz J. (2004). Posttranslational modifications of tau - Role in human tauopathies and modeling in transgenic animals. Current Drug Targets, 5 (6), 503-515. doi: 10.2174/1389450043345236 |
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2003 Journal Article β-amyloid induces paired helical filament-like tau filaments in tissue cultureFerrari, Alessandra, Hoerndli, Frederic, Baechi, Thomas, Nitsch, Roger M. and Gotz, Juergen (2003). β-amyloid induces paired helical filament-like tau filaments in tissue culture. Journal of Biological Chemistry, 278 (41), 40162-40168. doi: 10.1074/jbc.M308243200 |
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2003 Journal Article Activation of the ERK and JNK signaling pathways caused by neuron-specific inhibition of PP2A in transgenic miceKins, S, Kurosinski, P, Nitsch, RM and Gotz, J (2003). Activation of the ERK and JNK signaling pathways caused by neuron-specific inhibition of PP2A in transgenic mice. American Journal of Pathology, 163 (3), 833-843. doi: 10.1016/S0002-9440(10)63444-X |
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2003 Journal Article Expression of truncated PrP targeted to Purkinje cells of PrP knockout mice causes Purkinje cell death and ataxiaFlechsig, Eckhard, Hegyi, Ivan, Leimeroth, Rainer, Zuniga, Armando, Rossi, Daniela, Cozzio, Antonio, Schwarz, Petra, Rulicke, Thomas, Gotz, Juergen, Aguzzi, Adriano and Weissmann, Charles (2003). Expression of truncated PrP targeted to Purkinje cells of PrP knockout mice causes Purkinje cell death and ataxia. EMBO Journal, 22 (12), 3095-3101. doi: 10.1093/emboj/cdg285 |
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2003 Journal Article Saitohin gene is not associated with Alzheimer's diseaseStreffer, J. R., Papassotiropoulos, A., Kurosinski, P., Signorell, A., Wollmer, M. A., Tsolaki, M., Iakovidou, V., Horndli, F., Bosset, J., Gotz, J., Nitsch, R. M. and Hock, C. (2003). Saitohin gene is not associated with Alzheimer's disease. Journal of Neurology, Neurosurgery and Psychiatry, 74 (3), 362-363. doi: 10.1136/jnnp.74.3.362 |
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2003 Journal Article Protein Phosphatases: Transgenic and knockout models of PP2AGotz, J. and Schild, A. (2003). Protein Phosphatases: Transgenic and knockout models of PP2A. Methods in Enzymology, 366, 390-403. doi: 10.1016/S0076-6879(03)66029-5 |
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2002 Journal Article Diversity, developmental regulation and distribution of murine PR55/B subunits of protein phosphatase 2ASchmidt, Karsten, Kins, Stefan, Schild, Andreas, Nitsch, Roger M., Hemmings, Brian A. and Gotz, Juergen (2002). Diversity, developmental regulation and distribution of murine PR55/B subunits of protein phosphatase 2A. European Journal of Neuroscience, 16 (11), 2039-2048. doi: 10.1046/j.1460-9568.2002.02274.x |
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2002 Journal Article Glial cells under physiologic and pathologic conditionsKurosinski, Pascal, Biol, Dipl and Gotz, Jurgen (2002). Glial cells under physiologic and pathologic conditions. JAMA Neurology, 59 (10), 1524-1528. doi: 10.1001/archneur.59.10.1524 |
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2002 Journal Article Neurofibrillary tangle formation in transgenic mouse models of Alzheimer's diseaseChen, F, Nitsch, RM, Gotz, J, van Dorpe, J and Leuven, KU (2002). Neurofibrillary tangle formation in transgenic mouse models of Alzheimer's disease. Neurobiology of Aging, 23 (1), S233-S233. |
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2002 Journal Article Alzheimer's and Parkinson's disease - overlapping or synergistic pathologies?Kurosinski, P, Guggisberg, M and Gotz, J (2002). Alzheimer's and Parkinson's disease - overlapping or synergistic pathologies?. Trends in Molecular Medicine, 8 (1), 3-5. doi: 10.1016/S1471-4914(01)02246-8 |
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2001 Journal Article Reduced protein phosphatase 2A activity induces hyperphosphorylation and altered compartmentalization of tau in transgenic miceKins, Stefan, Crameri, Arames, Evans, David R. H., Hemmings, Brian A., Nitsch, Roger M. and Gotz, Juergen (2001). Reduced protein phosphatase 2A activity induces hyperphosphorylation and altered compartmentalization of tau in transgenic mice. Journal of Biological Chemistry, 276 (41), 38193-38200. |
