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2018 Journal Article Exosomes taken up by neurons hijack the endosomal pathway to spread to interconnected neuronsPolanco, Juan Carlos, Li, Chuanzhou, Durisic, Nela, Sullivan, Robert and Götz, Jürgen (2018). Exosomes taken up by neurons hijack the endosomal pathway to spread to interconnected neurons. Acta Neuropathologica Communications, 6 (1) 10, 1-14. doi: 10.1186/s40478-018-0514-4 |
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2018 Journal Article Safety and Efficacy of Scanning Ultrasound Treatment of Aged APP23 MiceLeinenga, Gerhard and Gotz, Jurgen (2018). Safety and Efficacy of Scanning Ultrasound Treatment of Aged APP23 Mice. Frontiers in Neuroscience, 12 (FEB) 55, 1-10. doi: 10.3389/fnins.2018.00055 |
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2018 Journal Article A Novel Antibody Targeting Tau Phosphorylated at Serine 235 Detects Neurofibrillary TanglesBrici, David, Götz, Jürgen and Nisbet, Rebecca M. (2018). A Novel Antibody Targeting Tau Phosphorylated at Serine 235 Detects Neurofibrillary Tangles. Journal of Alzheimer's Disease : JAD, 61 (3), 899-905. doi: 10.3233/JAD-170610 |
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2018 Journal Article Establishing sheep as an experimental species to validate ultrasound-mediated blood-brain barrier opening for potential therapeutic interventionsPelekanos, Matthew, Leinenga, Gerhard, Odabaee, Mostafa, Odabaee, Maryam, Saifzadeh, Siamak, Steck, Roland and Götz, Jürgen (2018). Establishing sheep as an experimental species to validate ultrasound-mediated blood-brain barrier opening for potential therapeutic interventions. Theranostics, 8 (9), 2583-2602. doi: 10.7150/thno.22852 |
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2018 Journal Article Multimodal analysis of aged wild-type mice exposed to repeated scanning ultrasound treatments demonstrates long-term safetyBlackmore, Daniel G., Turpin, Fabrice, Mohamed, Abdalla Z., Zong, Fangrong, Pandit, Rucha, Pelekanos, Matthew, Nasrallah, Fatima, Sah, Pankaj, Bartlett, Perry F. and Gotz, Juergen (2018). Multimodal analysis of aged wild-type mice exposed to repeated scanning ultrasound treatments demonstrates long-term safety. Theranostics, 8 (22), 6233-6247. doi: 10.7150/thno.27941 |
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2017 Journal Article Amyloid-β and tau complexity - towards improved biomarkers and targeted therapiesPolanco, Juan Carlos, Li, Chuanzhou, Bodea, Liviu-Gabriel, Martinez-Marmol, Ramon, Meunier, Frederic A and Götz, Jürgen (2017). Amyloid-β and tau complexity - towards improved biomarkers and targeted therapies. Nature reviews. Neurology, 14 (1), 22-40. doi: 10.1038/nrneurol.2017.162 |
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2017 Journal Article Retiring the term FTDP-17 as MAPT mutations are genetic forms of sporadic frontotemporal tauopathiesForrest, Shelley L., Kril, Jillian J., Stevens, Claire H., Kwok, John B., Hallupp, Marianne, Kim, Woojin S., Huang, Yue, McGinley, Ciara V., Werka, Hellen, Kiernan, Matthew C., Götz, Jürgen, Spillantini, Maria Grazia, Hodges, John R., Ittner, Lars M. and Halliday, Glenda M. (2017). Retiring the term FTDP-17 as MAPT mutations are genetic forms of sporadic frontotemporal tauopathies. Brain : A Journal of Neurology, 141 (2), 521-534. doi: 10.1093/brain/awx328 |
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2017 Journal Article Shedding light on mitophagy in neurons: what is the evidence for PINK1/Parkin mitophagy in vivo?Cummins, Nadia and Götz, Jürgen (2017). Shedding light on mitophagy in neurons: what is the evidence for PINK1/Parkin mitophagy in vivo?. Cellular and Molecular Life Sciences, 75 (7), 1-12. doi: 10.1007/s00018-017-2692-9 |
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2017 Journal Article A corticostriatal deficit promotes temporal distortion of automatic action in ageingMatamales, Miriam, Skrbis, Zala, Bailey, Matthew R, Balsam, Peter D, Balleine, Bernard W, Götz, Jürgen and Bertran-Gonzalez, Jesus (2017). A corticostriatal deficit promotes temporal distortion of automatic action in ageing. eLife, 6 e29908. doi: 10.7554/eLife.29908 |
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2017 Journal Article Tau-based therapies in neurodegeneration: opportunities and challengesLi, Chuanzhou and Götz, Jürgen (2017). Tau-based therapies in neurodegeneration: opportunities and challenges. Nature Reviews Drug Discovery, 16 (12), 863-883. doi: 10.1038/nrd.2017.155 |
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2017 Journal Article Somatodendritic accumulation of Tau in Alzheimer's disease is promoted by Fyn-mediated local protein translation.Li, Chuanzhou and Götz, Jürgen (2017). Somatodendritic accumulation of Tau in Alzheimer's disease is promoted by Fyn-mediated local protein translation.. EMBO Journal, 36 (17), 3120-3138. doi: 10.15252/embj.201797724 |
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2017 Journal Article Ultrasound as a treatment modality for neurological diseasesLeinenga, Gerhard, Nisbet, Rebecca M. and Gotz, Jurgen (2017). Ultrasound as a treatment modality for neurological diseases. Medical Journal of Australia, 206 (11), 470-471. doi: 10.5694/mja16.01013 |
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2017 Journal Article The amyloid-β oligomer Aβ∗56 induces specific alterations in neuronal signaling that lead to tau phosphorylation and aggregationAmar, Fatou, Sherman, Mathew A., Rush, Travis, Larson, Megan, Boyle, Gabriel, Chang, Liu, Gotz, Jurgen, Buisson, Alain and Lesne, Sylvain E. (2017). The amyloid-β oligomer Aβ∗56 induces specific alterations in neuronal signaling that lead to tau phosphorylation and aggregation. Science Signaling, 10 (478) aal2021, eaal2021. doi: 10.1126/scisignal.aal2021 |
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2017 Journal Article Combined effects of scanning ultrasound and a tau-specific single chain antibody in a tau transgenic mouse modelNisbet, Rebecca M., Van der Jeugd, Ann, Leinenga, Gerhard, Evans, Harrison T., Janowicz, Phillip W. and Goetz, Juergen (2017). Combined effects of scanning ultrasound and a tau-specific single chain antibody in a tau transgenic mouse model. Brain, 140 (5), 1220-1230. doi: 10.1093/brain/awx052 |
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2017 Journal Article Hyperphosphorylated tau causes reduced hippocampal CA1 excitability by relocating the axon initial segmentHatch, Robert John, Wei, Yan, Xia, Di and Gotz, Jürgen (2017). Hyperphosphorylated tau causes reduced hippocampal CA1 excitability by relocating the axon initial segment. Acta Neuropathologica, 133 (5), 717-730. doi: 10.1007/s00401-017-1674-1 |
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2017 Journal Article Mouse models of frontotemporal dementia: a comparison of phenotypes with clinical symptomatologyAhmed, Rebekah M., Irish, Muireann, van Eersel, Janet, Ittner, Arne, Ke, Yazi D., Volkerling, Alexander, van der Hoven, Julia, Tanaka, Kimi, Karl, Tim, Kassiou, Michael, Kril, Jillian J., Piguet, Olivier, Goetz, Juergen, Kiernan, Matthew C., Halliday, Glenda M., Hodges, John R. and Ittner, Lars M. (2017). Mouse models of frontotemporal dementia: a comparison of phenotypes with clinical symptomatology. Neuroscience and Biobehavioral Reviews, 74 (A), 126-138. doi: 10.1016/j.neubiorev.2017.01.004 |
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2017 Journal Article Accelerated aging exacerbates a pre-existing pathology in a tau transgenic mouse modelBodea, Liviu-Gabriel, Evans, Harrison Tudor, Van der Jeugd, Ann, Ittner, Lars M., Delerue, Fabien, Kril, Jillian, Halliday, Glenda, Hodges, John, Kiernan, Mathew C. and Goetz, Juergen (2017). Accelerated aging exacerbates a pre-existing pathology in a tau transgenic mouse model. Aging Cell, 16 (2), 377-386. doi: 10.1111/acel.12565 |
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2016 Journal Article Scanning ultrasound (SUS) causes no changes to neuronal excitability and prevents age-related reductions in hippocampal CA1 dendritic structure in wild-type miceHatch, Robert John, Leinenga, Gerhard and Götz, Jürgen (2016). Scanning ultrasound (SUS) causes no changes to neuronal excitability and prevents age-related reductions in hippocampal CA1 dendritic structure in wild-type mice. PloS One, 11 (10) e0164278, e0164278. doi: 10.1371/journal.pone.0164278 |
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2016 Journal Article Brain-derived neurotrophic factor protects against tau-related neurodegeneration of Alzheimer's diseaseJiao, S. -S., Shen, L. -L., Zhu, C., Bu, X. -L., Liu, Y. -H., Liu, C. -H., Yao, X. -Q., Zhang, L. -L., Zhou, H. -D., Walker, D. G., Tan, J., Goetz, J., Zhou, X. -F. and Wang, Y. -J. (2016). Brain-derived neurotrophic factor protects against tau-related neurodegeneration of Alzheimer's disease. Translational Psychiatry, 6 (10) e907, e907-e907. doi: 10.1038/tp.2016.186 |
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2016 Journal Article Munc18-1 is a molecular chaperone for α-synuclein, controlling its self-replicating aggregationChai, Ye Jin, Sierecki, Emma, Tomatis, Vanesa M., Gormal, Rachel S., Giles, Nichole, Morrow, Isabel C., Xia, Di, Götz, Jürgen, Parton, Robert G., Collins, Brett M., Gambin, Yann and Meunier, Frédéric A. (2016). Munc18-1 is a molecular chaperone for α-synuclein, controlling its self-replicating aggregation. The Journal of Cell Biology, 214 (6) 705, 705-718. doi: 10.1083/jcb.201512016 |
