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2016 Journal Article Scanning ultrasound (SUS) causes no changes to neuronal excitability and prevents age-related reductions in hippocampal CA1 dendritic structure in wild-type miceHatch, Robert John, Leinenga, Gerhard and Götz, Jürgen (2016). Scanning ultrasound (SUS) causes no changes to neuronal excitability and prevents age-related reductions in hippocampal CA1 dendritic structure in wild-type mice. PloS One, 11 (10) e0164278, e0164278. doi: 10.1371/journal.pone.0164278 |
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2016 Journal Article Brain-derived neurotrophic factor protects against tau-related neurodegeneration of Alzheimer's diseaseJiao, S. -S., Shen, L. -L., Zhu, C., Bu, X. -L., Liu, Y. -H., Liu, C. -H., Yao, X. -Q., Zhang, L. -L., Zhou, H. -D., Walker, D. G., Tan, J., Goetz, J., Zhou, X. -F. and Wang, Y. -J. (2016). Brain-derived neurotrophic factor protects against tau-related neurodegeneration of Alzheimer's disease. Translational Psychiatry, 6 (10) e907, e907-e907. doi: 10.1038/tp.2016.186 |
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2016 Journal Article Munc18-1 is a molecular chaperone for α-synuclein, controlling its self-replicating aggregationChai, Ye Jin, Sierecki, Emma, Tomatis, Vanesa M., Gormal, Rachel S., Giles, Nichole, Morrow, Isabel C., Xia, Di, Götz, Jürgen, Parton, Robert G., Collins, Brett M., Gambin, Yann and Meunier, Frédéric A. (2016). Munc18-1 is a molecular chaperone for α-synuclein, controlling its self-replicating aggregation. The Journal of Cell Biology, 214 (6) 705, 705-718. doi: 10.1083/jcb.201512016 |
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2016 Journal Article Special issue on 'Cytoskeletal proteins in health and neurodegenerative disease'Brandt, Roland and Goetz, Juergen (2016). Special issue on 'Cytoskeletal proteins in health and neurodegenerative disease'. Brain Research Bulletin, 126 (3), 213-216. doi: 10.1016/j.brainresbull.2016.08.003 |
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2016 Journal Article Motor cortical function determines prognosis in sporadic ALSShibuya, Kazumoto, Park, Susanna B., Geevasinga, Nimeshan, Menon, Parvathi, Howells, James, Simon, Neil G., Huynh, William, Noto, Yu-ichi, Gotz, Jurgen, Kril, Jillian J., Ittner, Lars M., Hodges, John, Halliday, Glenda, Vucic, Steve and Kiernan, Matthew C. (2016). Motor cortical function determines prognosis in sporadic ALS. Neurology, 87 (5), 513-520. doi: 10.1212/WNL.0000000000002912 |
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2016 Journal Article Tau physiology and pathomechanisms in frontotemporal lobar degenerationBodea, Liviu-Gabriel, Eckert, Anne, Ittner, Lars Matthias, Piguet, Olivier and Götz, Juergen (2016). Tau physiology and pathomechanisms in frontotemporal lobar degeneration. Journal of Neurochemistry, 138 (S1), 71-94. doi: 10.1111/jnc.13600 |
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2016 Journal Article Mobility and subcellular localization of endogenous, gene-edited Tau differs from that of over-expressed human wild-type and P301L mutant TauXia, Di, Gutmann, Julia M. and Gotz, Jurgen (2016). Mobility and subcellular localization of endogenous, gene-edited Tau differs from that of over-expressed human wild-type and P301L mutant Tau. Scientific Reports, 6 (1) 29074, 29074. doi: 10.1038/srep29074 |
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2016 Journal Article Quantitative imaging of cholinergic interneurons reveals a distinctive spatial organization and a functional gradient across the mouse striatumMatamales, Miriam, Gotz, Jurgen and Bertran-Gonzalez, Jesus (2016). Quantitative imaging of cholinergic interneurons reveals a distinctive spatial organization and a functional gradient across the mouse striatum. PLoS One, 11 (6) e0157682, 1-13. doi: 10.1371/journal.pone.0157682 |
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2016 Journal Article Extracellular vesicles isolated from the brains of rTg4510 mice seed tau protein aggregation in a threshold-dependent mannerPolanco, Juan Carlos, Scicluna, Benjamin James, Hill, Andrew Francis and Gotz, Jurgen (2016). Extracellular vesicles isolated from the brains of rTg4510 mice seed tau protein aggregation in a threshold-dependent manner. Journal of Biological Chemistry, 291 (24), 12445-12466. doi: 10.1074/jbc.M115.709485 |
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2016 Journal Article Aging-related dysfunction of striatal cholinergic interneurons produces conflict in action selectionMatamales, Miriam, Skrbis, Zala, Hatch, Robert J., Balleine, Bernard W., Gotz, Jurgen and Bertran-Gonzalez, Jesus (2016). Aging-related dysfunction of striatal cholinergic interneurons produces conflict in action selection. Neuron, 90 (2), 362-373. doi: 10.1016/j.neuron.2016.03.006 |
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2016 Journal Article Co-immunoprecipitation with Tau isoform-specific antibodies reveals distinct protein interactions and highlights a putative role for 2N Tau in diseaseLiu, Chang, Song, Xiaomin, Nisbet, Rebecca and Goetz, Juergen (2016). Co-immunoprecipitation with Tau isoform-specific antibodies reveals distinct protein interactions and highlights a putative role for 2N Tau in disease. Journal of Biological Chemistry, 291 (15), 8173-8188. doi: 10.1074/jbc.M115.641902 |
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2016 Journal Article A local insult of okadaic acid in wild-type mice induces tau phosphorylation and protein aggregation in anatomically distinct brain regionsBaker, Sian and Götz, Jürgen (2016). A local insult of okadaic acid in wild-type mice induces tau phosphorylation and protein aggregation in anatomically distinct brain regions. Acta Neuropathologica Communications, 4 (1) 32, 32.1-32.13. doi: 10.1186/s40478-016-0300-0 |
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2016 Journal Article Impulsivity, decreased social exploration, and executive dysfunction in a mouse model of frontotemporal dementiaVan der Jeugd, Ann, Vermaercke, Ben, Halliday, Glenda M., Staufenbiel, Matthias and Gotz, Jürgen (2016). Impulsivity, decreased social exploration, and executive dysfunction in a mouse model of frontotemporal dementia. Neurobiology of Learning and Memory, 130, 34-43. doi: 10.1016/j.nlm.2016.01.007 |
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2016 Journal Article The frontotemporal dementia-motor neuron disease continuumBurrell, James R., Halliday, Glenda M., Kril, Jillian J., Ittner, Lars M., Gotz, Jurgen, Kiernan, Matthew C. and Hodges, John R. (2016). The frontotemporal dementia-motor neuron disease continuum. The Lancet, 388 (10047), 919-931. doi: 10.1016/S0140-6736(16)00737-6 |
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2016 Journal Article Ultrasound treatment of neurological diseases — current and emerging applicationsLeinenga, Gerhard, Langton, Christian, Nisbet, Rebecca and Gotz, Jurgen (2016). Ultrasound treatment of neurological diseases — current and emerging applications. Nature Reviews Neurology, 12 (3), 161-174. doi: 10.1038/nrneurol.2016.13 |
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2016 Journal Article Extracellular vesicles containing P301L mutant tau accelerate pathological tau phosphorylation and oligomer formation but do not seed mature neurofibrillary tangles in ALZ17 miceBaker, Sian, Polanco, Juan Carlos and Gotz, Juergen (2016). Extracellular vesicles containing P301L mutant tau accelerate pathological tau phosphorylation and oligomer formation but do not seed mature neurofibrillary tangles in ALZ17 mice. Journal of Alzheimer's Disease, 54 (3), 1207-1217. doi: 10.3233/JAD-160371 |
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2016 Journal Article Glutamate receptors in alzheimer's disease: mechanisms and therapiesAnggono, Victor, Tsai, Li-Huei and Goetz, Juergen (2016). Glutamate receptors in alzheimer's disease: mechanisms and therapies. Neural Plasticity, 2016 8256196, 8256196-2. doi: 10.1155/2016/8256196 |
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2015 Journal Article No full admission for tau to the exclusive prion club yetPolanco, Juan Carlos and Götz, Jürgen (2015). No full admission for tau to the exclusive prion club yet. EMBO Journal, 34 (24), 2990-2992. doi: 10.15252/embj.201593311 |
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2015 Journal Article Sex hormone-related neurosteroids differentially rescue bioenergetic deficits induced by amyloid-β or hyperphosphorylated tau proteinGrimm, Amandine, Biliouris, Emily E., Lang, Undine E., Gotz, Jurgen, Mensah-Nyagan, Ayikoe Guy and Eckert, Anne (2015). Sex hormone-related neurosteroids differentially rescue bioenergetic deficits induced by amyloid-β or hyperphosphorylated tau protein. Cellular and Molecular Life Sciences, 73 (1), 201-215. doi: 10.1007/s00018-015-1988-x |
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2015 Journal Article FTD and ALS—translating mouse studies into clinical trialsIttner, Lars M., Halliday, Glenda M., Kril, Jillian J., Götz, Jürgen, Hodges, John R. and Kiernan, Matthew C. (2015). FTD and ALS—translating mouse studies into clinical trials. Nature Reviews Neurology, 11 (6), 360-366. doi: 10.1038/nrneurol.2015.65 |
