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2016 Journal Article Motor cortical function determines prognosis in sporadic ALSShibuya, Kazumoto, Park, Susanna B., Geevasinga, Nimeshan, Menon, Parvathi, Howells, James, Simon, Neil G., Huynh, William, Noto, Yu-ichi, Gotz, Jurgen, Kril, Jillian J., Ittner, Lars M., Hodges, John, Halliday, Glenda, Vucic, Steve and Kiernan, Matthew C. (2016). Motor cortical function determines prognosis in sporadic ALS. Neurology, 87 (5), 513-520. doi: 10.1212/WNL.0000000000002912 |
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2016 Journal Article Tau physiology and pathomechanisms in frontotemporal lobar degenerationBodea, Liviu-Gabriel, Eckert, Anne, Ittner, Lars Matthias, Piguet, Olivier and Götz, Juergen (2016). Tau physiology and pathomechanisms in frontotemporal lobar degeneration. Journal of Neurochemistry, 138 (S1), 71-94. doi: 10.1111/jnc.13600 |
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2016 Journal Article Mobility and subcellular localization of endogenous, gene-edited Tau differs from that of over-expressed human wild-type and P301L mutant TauXia, Di, Gutmann, Julia M. and Gotz, Jurgen (2016). Mobility and subcellular localization of endogenous, gene-edited Tau differs from that of over-expressed human wild-type and P301L mutant Tau. Scientific Reports, 6 (1) 29074, 29074. doi: 10.1038/srep29074 |
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2016 Journal Article Quantitative imaging of cholinergic interneurons reveals a distinctive spatial organization and a functional gradient across the mouse striatumMatamales, Miriam, Gotz, Jurgen and Bertran-Gonzalez, Jesus (2016). Quantitative imaging of cholinergic interneurons reveals a distinctive spatial organization and a functional gradient across the mouse striatum. PLoS One, 11 (6) e0157682, 1-13. doi: 10.1371/journal.pone.0157682 |
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2016 Journal Article Extracellular vesicles isolated from the brains of rTg4510 mice seed tau protein aggregation in a threshold-dependent mannerPolanco, Juan Carlos, Scicluna, Benjamin James, Hill, Andrew Francis and Gotz, Jurgen (2016). Extracellular vesicles isolated from the brains of rTg4510 mice seed tau protein aggregation in a threshold-dependent manner. Journal of Biological Chemistry, 291 (24), 12445-12466. doi: 10.1074/jbc.M115.709485 |
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2016 Journal Article Aging-related dysfunction of striatal cholinergic interneurons produces conflict in action selectionMatamales, Miriam, Skrbis, Zala, Hatch, Robert J., Balleine, Bernard W., Gotz, Jurgen and Bertran-Gonzalez, Jesus (2016). Aging-related dysfunction of striatal cholinergic interneurons produces conflict in action selection. Neuron, 90 (2), 362-373. doi: 10.1016/j.neuron.2016.03.006 |
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2016 Journal Article Co-immunoprecipitation with Tau isoform-specific antibodies reveals distinct protein interactions and highlights a putative role for 2N Tau in diseaseLiu, Chang, Song, Xiaomin, Nisbet, Rebecca and Goetz, Juergen (2016). Co-immunoprecipitation with Tau isoform-specific antibodies reveals distinct protein interactions and highlights a putative role for 2N Tau in disease. Journal of Biological Chemistry, 291 (15), 8173-8188. doi: 10.1074/jbc.M115.641902 |
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2016 Journal Article A local insult of okadaic acid in wild-type mice induces tau phosphorylation and protein aggregation in anatomically distinct brain regionsBaker, Sian and Götz, Jürgen (2016). A local insult of okadaic acid in wild-type mice induces tau phosphorylation and protein aggregation in anatomically distinct brain regions. Acta Neuropathologica Communications, 4 (1) 32, 32.1-32.13. doi: 10.1186/s40478-016-0300-0 |
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2016 Journal Article Impulsivity, decreased social exploration, and executive dysfunction in a mouse model of frontotemporal dementiaVan der Jeugd, Ann, Vermaercke, Ben, Halliday, Glenda M., Staufenbiel, Matthias and Gotz, Jürgen (2016). Impulsivity, decreased social exploration, and executive dysfunction in a mouse model of frontotemporal dementia. Neurobiology of Learning and Memory, 130, 34-43. doi: 10.1016/j.nlm.2016.01.007 |
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2016 Journal Article The frontotemporal dementia-motor neuron disease continuumBurrell, James R., Halliday, Glenda M., Kril, Jillian J., Ittner, Lars M., Gotz, Jurgen, Kiernan, Matthew C. and Hodges, John R. (2016). The frontotemporal dementia-motor neuron disease continuum. The Lancet, 388 (10047), 919-931. doi: 10.1016/S0140-6736(16)00737-6 |
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2016 Journal Article Ultrasound treatment of neurological diseases — current and emerging applicationsLeinenga, Gerhard, Langton, Christian, Nisbet, Rebecca and Gotz, Jurgen (2016). Ultrasound treatment of neurological diseases — current and emerging applications. Nature Reviews Neurology, 12 (3), 161-174. doi: 10.1038/nrneurol.2016.13 |
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2016 Journal Article Extracellular vesicles containing P301L mutant tau accelerate pathological tau phosphorylation and oligomer formation but do not seed mature neurofibrillary tangles in ALZ17 miceBaker, Sian, Polanco, Juan Carlos and Gotz, Juergen (2016). Extracellular vesicles containing P301L mutant tau accelerate pathological tau phosphorylation and oligomer formation but do not seed mature neurofibrillary tangles in ALZ17 mice. Journal of Alzheimer's Disease, 54 (3), 1207-1217. doi: 10.3233/JAD-160371 |
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2016 Journal Article Glutamate receptors in alzheimer's disease: mechanisms and therapiesAnggono, Victor, Tsai, Li-Huei and Goetz, Juergen (2016). Glutamate receptors in alzheimer's disease: mechanisms and therapies. Neural Plasticity, 2016 8256196, 8256196-2. doi: 10.1155/2016/8256196 |
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2015 Journal Article No full admission for tau to the exclusive prion club yetPolanco, Juan Carlos and Götz, Jürgen (2015). No full admission for tau to the exclusive prion club yet. EMBO Journal, 34 (24), 2990-2992. doi: 10.15252/embj.201593311 |
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2015 Journal Article Sex hormone-related neurosteroids differentially rescue bioenergetic deficits induced by amyloid-β or hyperphosphorylated tau proteinGrimm, Amandine, Biliouris, Emily E., Lang, Undine E., Gotz, Jurgen, Mensah-Nyagan, Ayikoe Guy and Eckert, Anne (2015). Sex hormone-related neurosteroids differentially rescue bioenergetic deficits induced by amyloid-β or hyperphosphorylated tau protein. Cellular and Molecular Life Sciences, 73 (1), 201-215. doi: 10.1007/s00018-015-1988-x |
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2015 Journal Article FTD and ALS—translating mouse studies into clinical trialsIttner, Lars M., Halliday, Glenda M., Kril, Jillian J., Götz, Jürgen, Hodges, John R. and Kiernan, Matthew C. (2015). FTD and ALS—translating mouse studies into clinical trials. Nature Reviews Neurology, 11 (6), 360-366. doi: 10.1038/nrneurol.2015.65 |
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2015 Journal Article Pseudophosphorylation of Tau at distinct epitopes or the presence of the P301L mutation targets the microtubule-associated protein Tau to dendritic spinesXia, Di, Li, Chuanzhou and Gotz, Jurgen (2015). Pseudophosphorylation of Tau at distinct epitopes or the presence of the P301L mutation targets the microtubule-associated protein Tau to dendritic spines. Biochimica et Biophysica Acta - Molecular Basis of Disease, 1852 (5), 913-924. doi: 10.1016/j.bbadis.2014.12.017 |
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2015 Journal Article Dementia and neurodegeneration - role of mitochondria and oxidative stress in Alzheimer's diseaseCummins, Nadia and Götz, Jurgen (2015). Dementia and neurodegeneration - role of mitochondria and oxidative stress in Alzheimer's disease. Australian Biochemist, 46 (1), 4-7. |
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2015 Journal Article Scanning ultrasound removes amyloid-beta and restores memory in an Alzheimer's disease mouse modelLeinenga, Gerhard and Götz, Jürgen (2015). Scanning ultrasound removes amyloid-beta and restores memory in an Alzheimer's disease mouse model. Science Translational Medicine, 7 (278) ARTN 278ra33, 278ra33.1-278ra33.12. doi: 10.1126/scitranslmed.aaa2512 |
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2015 Journal Article Neuronal protein with tau-like repeats (PTL-1) regulates intestinal SKN-1 nuclear accumulation in response to oxidative stressChew, Yee Lian, Gotz, Jurgen and Nicholas, Hannah R. (2015). Neuronal protein with tau-like repeats (PTL-1) regulates intestinal SKN-1 nuclear accumulation in response to oxidative stress. Aging Cell, 14 (1), 148-151. doi: 10.1111/acel.12285 |
