2022 Journal Article Isolation and culture of pure adult mouse microglia and astrocytes for in vitro characterization and analysesMilner, Mark T., Lawrence, Grace M. E. P., Holley, Caroline L., Bodea, Liviu-Gabriel, Götz, Jürgen, Burgener, Sabrina S. and Schroder, Kate (2022). Isolation and culture of pure adult mouse microglia and astrocytes for in vitro characterization and analyses. STAR Protocols, 3 (2) 101295, 1-16. doi: 10.1016/j.xpro.2022.101295 |
2022 Journal Article Ultrasound-mediated bioeffects in senescent mice and Alzheimer’s mouse modelsBalbi, Matilde, Blackmore, Daniel G., Padmanabhan, Pranesh and Götz, Jürgen (2022). Ultrasound-mediated bioeffects in senescent mice and Alzheimer’s mouse models. Brain Sciences, 12 (6) 775, 1-12. doi: 10.3390/brainsci12060775 |
2022 Journal Article Transcriptional signature in microglia isolated from an Alzheimer's disease mouse model treated with scanning ultrasoundLeinenga, Gerhard, Bodea, Liviu‐Gabriel, Schröder, Jan, Sun, Giuzhi, Zhou, Yichen, Song, Jae, Grubman, Alexandra, Polo, Jose M. and Götz, Jürgen (2022). Transcriptional signature in microglia isolated from an Alzheimer's disease mouse model treated with scanning ultrasound. Bioengineering & Translational Medicine, 8 (1) e10329, e10329. doi: 10.1002/btm2.10329 |
2022 Journal Article Claudin-5 binder enhances focused ultrasound-mediated opening in an in vitro blood-brain barrier modelChen, Liyu, Sutharsan, Ratneswary, Lee, Jonathan LF, Cruz, Esteban, Asnicar, Blaise, Palliyaguru, Tishila, Wasielewska, Joanna M, Gaudin, Arnaud, Song, Jae, Leinenga, Gerhard and Götz, Jürgen (2022). Claudin-5 binder enhances focused ultrasound-mediated opening in an in vitro blood-brain barrier model. Theranostics, 12 (5), 1952-1970. doi: 10.7150/thno.65539 |
2022 Journal Article A sporadic Alzheimer’s blood-brain barrier model for developing ultrasound-mediated delivery of Aducanumab and anti-Tau antibodiesWasielewska, Joanna M., Chaves, Juliana C.S., Johnston, Rebecca L., Milton, Laura A., Hernández, Damián, Chen, Liyu, Song, Jae, Lee, Wendy, Leinenga, Gerhard, Nisbet, Rebecca M., Pébay, Alice, Götz, Jürgen, White, Anthony R. and Oikari, Lotta E. (2022). A sporadic Alzheimer’s blood-brain barrier model for developing ultrasound-mediated delivery of Aducanumab and anti-Tau antibodies. Theranostics, 12 (16), 6826-6847. doi: 10.7150/thno.72685 |
2021 Journal Article Super-resolution microscopy: a closer look at synaptic dysfunction in Alzheimer diseasePadmanabhan, Pranesh, Kneynsberg, Andrew and Götz, Jürgen (2021). Super-resolution microscopy: a closer look at synaptic dysfunction in Alzheimer disease. Nature Reviews Neuroscience, 22 (12), 723-740. doi: 10.1038/s41583-021-00531-y |
2021 Journal Article Therapeutic ultrasound as a treatment modality for physiological and pathological ageing including Alzheimer’s diseaseGötz, Jürgen, Richter-Stretton, Gina and Cruz, Esteban (2021). Therapeutic ultrasound as a treatment modality for physiological and pathological ageing including Alzheimer’s disease. Pharmaceutics, 13 (7) 1002, 1002. doi: 10.3390/pharmaceutics13071002 |
2021 Journal Article Exosomal and vesicle-free tau seeds - propagation and convergence in endolysosomal permeabilizationPolanco, Juan Carlos and Götz, Jürgen (2021). Exosomal and vesicle-free tau seeds - propagation and convergence in endolysosomal permeabilization. The FEBS Journal, 289 (22) febs.16055, 6891-6907. doi: 10.1111/febs.16055 |
2021 Journal Article Altered ribosomal function and protein synthesis caused by tauEvans, Harrison Tudor, Taylor, Deonne, Kneynsberg, Andrew, Bodea, Liviu-Gabriel and Götz, Jürgen (2021). Altered ribosomal function and protein synthesis caused by tau. Acta Neuropathologica Communications, 9 (1) 110, 110. doi: 10.1186/s40478-021-01208-4 |
2021 Journal Article PINK1 and parkin shape the organism-wide distribution of a deleterious mitochondrial genomeAhier, Arnaud, Dai, Chuan-Yang, Kirmes, Ina, Cummins, Nadia, Hung, Grace Ching Ching, Götz, Jürgen and Zuryn, Steven (2021). PINK1 and parkin shape the organism-wide distribution of a deleterious mitochondrial genome. Cell Reports, 35 (9) 109203, 109203. doi: 10.1016/j.celrep.2021.109203 |
2021 Journal Article Alzheimer's disease research progress in Australia: The Alzheimer's Association International Conference Satellite Symposium in SydneySexton, Claire E, Anstey, Kaarin J, Baldacci, Filippo, Barnum, C J, Barron, Anna M, Blennow, Kaj, Brodaty, Henry, Burnham, Samantha, Elahi, Fanny M, Götz, Jürgen, Jeon, Yun-Hee, Koronyo-Hamaoui, Maya, Landau, Susan M, Lautenschlager, Nicola T, Laws, Simon M, Lipnicki, Darren M, Lu, Hanzhang, Masters, Colin L, Moyle, Wendy, Nakamura, Akinori, Pasinetti, Giulio Maria, Rao, Naren, Rowe, Christopher, Sachdev, Perminder S, Schofield, Peter R, Sigurdsson, Einar M, Smith, Kate, Srikanth, Velandai, Szoeke, Cassandra ... Carrillo, Maria C (2021). Alzheimer's disease research progress in Australia: The Alzheimer's Association International Conference Satellite Symposium in Sydney. Alzheimer's & dementia : the journal of the Alzheimer's Association, 18 (1) alz.12380, 178-190. doi: 10.1002/alz.12380 |
2021 Journal Article Low-intensity ultrasound restores long-term potentiation and memory in senescent mice through pleiotropic mechanisms including NMDAR signalingBlackmore, Daniel G., Turpin, Fabrice, Palliyaguru, Tishila, Evans, Harrison T., Chicoteau, Antony, Lee, Wendy, Pelekanos, Matthew, Nguyen, Nghia, Song, Jae, Sullivan, Robert K. P., Sah, Pankaj, Bartlett, Perry F. and Götz, Jürgen (2021). Low-intensity ultrasound restores long-term potentiation and memory in senescent mice through pleiotropic mechanisms including NMDAR signaling. Molecular Psychiatry, 26 (11), 6975-6991. doi: 10.1038/s41380-021-01129-7 |
2021 Journal Article A comparative study of the effects of Aducanumab and scanning ultrasound on amyloid plaques and behavior in the APP23 mouse model of Alzheimer diseaseLeinenga, Gerhard, Koh, Wee Kiat and Götz, Jürgen (2021). A comparative study of the effects of Aducanumab and scanning ultrasound on amyloid plaques and behavior in the APP23 mouse model of Alzheimer disease. Alzheimer's Research and Therapy, 13 (1) 76, 1-14. doi: 10.1186/s13195-021-00809-4 |
2021 Journal Article De novo proteomic methods for examining the molecular mechanisms underpinning long-term memoryEvans, Harrison Tudor, Blackmore, Daniel, Goetz, Juergen and Bodea, Liviu-Gabriel (2021). De novo proteomic methods for examining the molecular mechanisms underpinning long-term memory. Brain Research Bulletin, 169, 94-103. doi: 10.1016/j.brainresbull.2020.12.015 |
2021 Journal Article Tau antibody isotype induces differential effects following passive immunisation of tau transgenic miceBajracharya, Rinie, Brici, David, Bodea, Liviu-Gabriel, Janowicz, Phillip W., Götz, Jürgen and Nisbet, Rebecca M. (2021). Tau antibody isotype induces differential effects following passive immunisation of tau transgenic mice. Acta Neuropathologica Communications, 9 (1) 42, 1-13. doi: 10.1186/s40478-021-01147-0 |
2021 Journal Article The NLRP3 inflammasome triggers sterile neuroinflammation and Alzheimer’s diseaseMilner, Mark T, Maddugoda, Madhavi, Götz, Jürgen, Burgener, Sabrina S and Schroder, Kate (2021). The NLRP3 inflammasome triggers sterile neuroinflammation and Alzheimer’s disease. Current Opinion in Immunology, 68, 116-124. doi: 10.1016/j.coi.2020.10.011 |
2021 Journal Article Exosomes induce endolysosomal permeabilization as a gateway by which exosomal tau seeds escape into the cytosolPolanco, Juan Carlos, Hand, Gabriel Rhys, Briner, Adam, Li, Chuanzhou and Götz, Jürgen (2021). Exosomes induce endolysosomal permeabilization as a gateway by which exosomal tau seeds escape into the cytosol. Acta Neuropathologica, 141 (2), 235-256. doi: 10.1007/s00401-020-02254-3 |
2020 Journal Article Role for caveolin-mediated transcytosis in facilitating transport of large cargoes into the brain via ultrasoundPandit, Rucha, Koh, Wee Kiat, Sullivan, Robert K.P., Palliyaguru, Tishila, Parton, Robert G. and Götz, Jürgen (2020). Role for caveolin-mediated transcytosis in facilitating transport of large cargoes into the brain via ultrasound. Journal of Controlled Release, 327, 667-675. doi: 10.1016/j.jconrel.2020.09.015 |
2020 Journal Article Fyn kinase controls tau aggregation in vivoBriner, Adam, Götz, Jürgen and Polanco, Juan Carlos (2020). Fyn kinase controls tau aggregation in vivo. Cell Reports, 32 (7) 108045, 108045. doi: 10.1016/j.celrep.2020.108045 |
2020 Journal Article Delivery of antibodies into the brain using focused scanning ultrasoundLeinenga, Gerhard, Bodea, Liviu-Gabriel, Koh, Wee Kiat, Nisbet, Rebecca M. and Götz, Jürgen (2020). Delivery of antibodies into the brain using focused scanning ultrasound. Journal of Visualized Experiments, 2020 (161) e61372, 1-13. doi: 10.3791/61372 |