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2015

Journal Article

What we can learn from animal models about cerebral multi-morbidity

Baker, Sian and Gotz, Jurgen (2015). What we can learn from animal models about cerebral multi-morbidity. Alzheimer's Research and Therapy, 7 (11) 11, 11. doi: 10.1186/s13195-015-0097-2

What we can learn from animal models about cerebral multi-morbidity

2015

Journal Article

Connecting the dots between tau dysfunction and neurodegeneration

Frost, Bess, Gotz, Jurgen and Feany, Mel B. (2015). Connecting the dots between tau dysfunction and neurodegeneration. Trends in Cell Biology, 25 (1), 46-53. doi: 10.1016/j.tcb.2014.07.005

Connecting the dots between tau dysfunction and neurodegeneration

2014

Journal Article

Tau aggregation and its interplay with amyloid-β

Nisbet, Rebecca M., Polanco, Juan-Carlos, Ittner, Lars M. and Gotz, Jurgen (2014). Tau aggregation and its interplay with amyloid-β. Acta Neuropathologica, 129 (2), 207-220. doi: 10.1007/s00401-014-1371-2

Tau aggregation and its interplay with amyloid-β

2014

Journal Article

Granulovacuolar degeneration and unfolded protein response in mouse models of tauopathy and Aβ amyloidosis

Kohler, Christoph, Dinekov, Maja and Gotz, Jürgen (2014). Granulovacuolar degeneration and unfolded protein response in mouse models of tauopathy and Aβ amyloidosis. Neurobiology of Disease, 71, 169-179. doi: 10.1016/j.nbd.2014.07.006

Granulovacuolar degeneration and unfolded protein response in mouse models of tauopathy and Aβ amyloidosis

2014

Journal Article

Bio-orthogonal labeling as a tool to visualize and identify newly synthesized proteins in Caenorhabditis elegans

Ullrich, Milena, Liang, Vanessa, Chew, Yee Lian, Banister, Samuel, Song, Xiaomin, Zaw, Thiri, Lam, Hong, Berber, Slavica, Kassiou, Michael, Nicholas, Hannah R. and Goetz, Juergen (2014). Bio-orthogonal labeling as a tool to visualize and identify newly synthesized proteins in Caenorhabditis elegans. Nature Protocols, 9 (9), 2237-2255. doi: 10.1038/nprot.2014.150

Bio-orthogonal labeling as a tool to visualize and identify newly synthesized proteins in Caenorhabditis elegans

2014

Journal Article

Altered proteostasis in aging and heat shock response in C. elegans revealed by analysis of the global and de novo synthesized proteome

Liang, Vanessa, Ullrich, Milena, Lam, Hong, Chew, Yee Lian, Banister, Samuel, Song, Xiaomin, Zaw, Thiri, Kassiou, Michael, Gotz, Jürgen and Nicholas, Hannah R. (2014). Altered proteostasis in aging and heat shock response in C. elegans revealed by analysis of the global and de novo synthesized proteome. Cellular and Molecular Life Sciences, 71 (17), 3339-3361. doi: 10.1007/s00018-014-1558-7

Altered proteostasis in aging and heat shock response in C. elegans revealed by analysis of the global and de novo synthesized proteome

2014

Journal Article

Tau-targeting passive immunization modulates aspects of pathology in tau transgenic mice

Ittner, Arne, Bertz, Josefine, Suh, Lisa S., Stevens, Claire H., Gotz, Jurgen and Ittner, Lars M. (2014). Tau-targeting passive immunization modulates aspects of pathology in tau transgenic mice. Journal of Neurochemistry, 132 (1), 1-11. doi: 10.1111/jnc.12821

Tau-targeting passive immunization modulates aspects of pathology in tau transgenic mice

2014

Journal Article

Regulation of age-related structural integrity in neurons by protein with tau-like repeats (PTL-1) is cell autonomous

Chew, Yee Lian, Fan, Xiaochen, Gotz, Jurgen and Nicholas, Hannah R. (2014). Regulation of age-related structural integrity in neurons by protein with tau-like repeats (PTL-1) is cell autonomous. Scientific Reports, 4 (1) 5185, 5185. doi: 10.1038/srep05185

Regulation of age-related structural integrity in neurons by protein with tau-like repeats (PTL-1) is cell autonomous

2014

Journal Article

Premature lethality, hyperactivity, and aberrant phosphorylation in transgenic mice expressing a constitutively active form of Fyn

Xia, Di and Gotz, Jurgen (2014). Premature lethality, hyperactivity, and aberrant phosphorylation in transgenic mice expressing a constitutively active form of Fyn. Frontiers in Molecular Neuroscience, 7 (MAY) 40, 1-11. doi: 10.3389/fnmol.2014.00040

Premature lethality, hyperactivity, and aberrant phosphorylation in transgenic mice expressing a constitutively active form of Fyn

2014

Journal Article

Visualizing the microtubule-associated protein tau in the nucleus

Lu, Jing, Li, Ting, He, RongQiao, Bartlett, Perry F. and Gotz, Jürgen (2014). Visualizing the microtubule-associated protein tau in the nucleus. Science China Life Sciences, 57 (4), 422-431. doi: 10.1007/s11427-014-4635-0

Visualizing the microtubule-associated protein tau in the nucleus

2014

Journal Article

The herbal compound geniposide rescues formaldehyde-induced apoptosis in N2a neuroblastoma cells

Chen, JinYan, Sun, MengRu, Wang, XingHua, Lu, Jing, Wei, Yan, Tan, Yan, Liu, Ying, Gotz J., He, RongQiao and Hua, Qian (2014). The herbal compound geniposide rescues formaldehyde-induced apoptosis in N2a neuroblastoma cells. Science China Life Sciences, 57 (4), 412-421. doi: 10.1007/s11427-014-4643-0

The herbal compound geniposide rescues formaldehyde-induced apoptosis in N2a neuroblastoma cells

2013

Journal Article

Profiling murine tau with 0N, 1N and 2N isoform-specific antibodies in brain and peripheral organs reveals distinct subcellular localization, with the 1N isoform being enriched in the nucleus

Liu, Chang and Goetz, Juergen (2013). Profiling murine tau with 0N, 1N and 2N isoform-specific antibodies in brain and peripheral organs reveals distinct subcellular localization, with the 1N isoform being enriched in the nucleus. PloS One, 8 (12) e84849, e84849. doi: 10.1371/journal.pone.0084849

Profiling murine tau with 0N, 1N and 2N isoform-specific antibodies in brain and peripheral organs reveals distinct subcellular localization, with the 1N isoform being enriched in the nucleus

2013

Journal Article

March separate, strike together: role of phosphorylated TAU in mitochondrial dysfunction in Alzheimer's disease

Eckert, Anne, Nisbet, Rebecca, Grimm, Amandine and Götz, Jürgen (2013). March separate, strike together: role of phosphorylated TAU in mitochondrial dysfunction in Alzheimer's disease. Biochimica et Biophysica Acta (BBA): Molecular Basis of Disease, 1842 (8), 1258-1266. doi: 10.1016/j.bbadis.2013.08.013

March separate, strike together: role of phosphorylated TAU in mitochondrial dysfunction in Alzheimer's disease

2013

Journal Article

Aging in the nervous system of Caenorhabditis elegans

Chew, Yee Lian, Fan, Xiaochen, Goetz, Juergen and Nicholas, Hannah R. (2013). Aging in the nervous system of Caenorhabditis elegans. Communicative and Integrative Biology, 6 (5) e25288, e25288.1-e25288.6. doi: 10.4161/cib.25288

Aging in the nervous system of Caenorhabditis elegans

2013

Journal Article

Lessons from two prevalent amyloidoses-what amylin and A beta have in common

Goetz, Juergen, Lim, Yun-An and Eckert, Anne (2013). Lessons from two prevalent amyloidoses-what amylin and A beta have in common. Frontiers in Aging Neuroscience, 5 (AUG) Article 38, 38.1-38.9. doi: 10.3389/fnagi.2013.00038

Lessons from two prevalent amyloidoses-what amylin and A beta have in common

2013

Journal Article

Proximal interphalangeal joint replacement with an unconstrained pyrocarbon prosthesis (Ascension®): a long-term follow-up

Heers, G., Springorum, H. R., Baier, C., Götz, J., Grifka, J. and Renkawitz, T. (2013). Proximal interphalangeal joint replacement with an unconstrained pyrocarbon prosthesis (Ascension®): a long-term follow-up. Journal of Hand Surgery: European Volume, 38 (6), 680-685. doi: 10.1177/1753193412469898

Proximal interphalangeal joint replacement with an unconstrained pyrocarbon prosthesis (Ascension®): a long-term follow-up

2013

Journal Article

What renders TAU toxic

Goetz, Juergen, Xia, Di, Leinenga, Gerhard, Chew, Yee Lian and Nicholas, Hannah R. (2013). What renders TAU toxic. Frontiers in Neurology, 4 Article 72, 72.1-72.10. doi: 10.3389/fneur.2013.00072

What renders TAU toxic

2013

Journal Article

Why size matters - balancing mitochondrial dynamics in Alzheimer's disease

DuBoff, Brian, Feany, Mel and Goetz, Juergen (2013). Why size matters - balancing mitochondrial dynamics in Alzheimer's disease. Trends in Neurosciences, 36 (6), 325-335. doi: 10.1016/j.tins.2013.03.002

Why size matters - balancing mitochondrial dynamics in Alzheimer's disease

2013

Journal Article

Glutamate metabolism is impaired in transgenic mice with tau hyperphosphorylation

Nilsen, Linn Hege, Rae, Caroline, Ittner, Lars M., Goetz, Juergen and Sonnewald, Ursula (2013). Glutamate metabolism is impaired in transgenic mice with tau hyperphosphorylation. Journal of Cerebral Blood Flow and Metabolism, 33 (5), 684-691. doi: 10.1038/jcbfm.2012.212

Glutamate metabolism is impaired in transgenic mice with tau hyperphosphorylation

2013

Journal Article

Active glycogen synthase kinase-3 and tau pathology-related tyrosine phosphorylation in pR5 human tau transgenic mice

Koehler, Christoph, Dinekov, Maja and Goetz, Juergen (2013). Active glycogen synthase kinase-3 and tau pathology-related tyrosine phosphorylation in pR5 human tau transgenic mice. Neurobiology of Aging, 34 (5), 1369-1379. doi: 10.1016/j.neurobiolaging.2012.11.010

Active glycogen synthase kinase-3 and tau pathology-related tyrosine phosphorylation in pR5 human tau transgenic mice