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2009

Journal Article

Response to the comment 'Iron, type 2 diabetes mellitus, and Alzheimer's disease' to our Visions and Reflections article 'Common features between diabetes mellitus and Alzheimer's disease'

Götz, Jürgen, Ittner, Lars M. and Lim, Yun-An (2009). Response to the comment 'Iron, type 2 diabetes mellitus, and Alzheimer's disease' to our Visions and Reflections article 'Common features between diabetes mellitus and Alzheimer's disease'. Cellular and Molecular Life Sciences, 66 (17), 2945-2945. doi: 10.1007/s00018-009-0073-8

Response to the comment 'Iron, type 2 diabetes mellitus, and Alzheimer's disease' to our Visions and Reflections article 'Common features between diabetes mellitus and Alzheimer's disease'

2009

Journal Article

Phosphorylated Tau interacts with c-Jun N-terminal kinase-interacting protein 1 (JIP1) in Alzheimer disease

Ittner, Lars M., Ke, Yazi D. and Gotz, Jurgen (2009). Phosphorylated Tau interacts with c-Jun N-terminal kinase-interacting protein 1 (JIP1) in Alzheimer disease. Journal of Biological Chemistry, 284 (31), 20909-20916. doi: 10.1074/jbc.M109.014472

Phosphorylated Tau interacts with c-Jun N-terminal kinase-interacting protein 1 (JIP1) in Alzheimer disease

2009

Journal Article

Common features between diabetes mellitus and Alzheimer's disease

Götz, J., Ittner, L. M. and Lim, Y. A. (2009). Common features between diabetes mellitus and Alzheimer's disease. Cellular and Molecular Life Sciences, 66 (8), 1321-1325. doi: 10.1007/s00018-009-9070-1

Common features between diabetes mellitus and Alzheimer's disease

2009

Journal Article

Substrate-specific reduction of PP2A activity exaggerates tau pathology

Deters, Natasha, Ittner, Lars M. and Gotz, Jurgen (2009). Substrate-specific reduction of PP2A activity exaggerates tau pathology. Biochemical and Biophysical Research Communications, 379 (2), 400-405. doi: 10.1016/j.bbrc.2008.12.140

Substrate-specific reduction of PP2A activity exaggerates tau pathology

2009

Journal Article

Phosphorylation of soluble tau differs in Pick's disease and Alzheimer's disease brains

van Eersel, Janet, Bi, Mian, Ke, Yazi D., Hodges, John R., Xuereb, John H., Gregory, Gillian C., Halliday, Glenda M., Gotz, Jurgen, Kril, Jillian J. and Ittner, Lars M. (2009). Phosphorylation of soluble tau differs in Pick's disease and Alzheimer's disease brains. Journal of Neural Transmission, 116 (10), 1243-1251. doi: 10.1007/s00702-009-0293-y

Phosphorylation of soluble tau differs in Pick's disease and Alzheimer's disease brains

2009

Journal Article

Primary support cultures of hippocampal and substantia nigra neurons

Fath, Thomas, Ke, Yazi D., Gunning, Peter, Gotz, Jürgen and Ittner, Lars M. (2009). Primary support cultures of hippocampal and substantia nigra neurons. Nature Protocols, 4 (1), 78-85. doi: 10.1038/nprot.2008.199

Primary support cultures of hippocampal and substantia nigra neurons

2009

Journal Article

Alzheimer's disease selective vulnerability and modeling in transgenic Mice

Gotz, Jurgen, Schonrock, Nicole, Vissel, Bryce and Ittner, Lars M. (2009). Alzheimer's disease selective vulnerability and modeling in transgenic Mice. Journal of Alzheimer's Disease, 18 (2), 243-251. doi: 10.3233/JAD-2009-1143

Alzheimer's disease selective vulnerability and modeling in transgenic Mice

2008

Journal Article

An update on the toxicity of A-beta in Alzheimer's disease

Götz, Jurgen, Ittner, Lars M, Schonrock, Nicole and Cappai, Roberto (2008). An update on the toxicity of A-beta in Alzheimer's disease. Neuropsychiatric Disease and Treatment, 4 (6), 1033-1042. doi: 10.2147/NDT.S3016

An update on the toxicity of A-beta in Alzheimer's disease

2008

Journal Article

Parkinsonism and impaired axonal transport in a mouse model of frontotemporal dementia

Ittner, Lars M., Fath, Thomas, Ke, Yazi D., Bi, Mian, van Eersel, Janet, Li, Kong M., Gunning, Peter and Gotz, Jurgen (2008). Parkinsonism and impaired axonal transport in a mouse model of frontotemporal dementia. Proceedings of the National Academy of Sciences of the United States of America, 105 (41), 15997-16002. doi: 10.1073/pnas.0808084105

Parkinsonism and impaired axonal transport in a mouse model of frontotemporal dementia

2008

Journal Article

Pathogenetic mechanisms in Down Syndrome

Einfeld, S., Goetz, J. and Holsinger, R. M. D. (2008). Pathogenetic mechanisms in Down Syndrome. Journal of Intellectual Disability Research, 52 (10), 813-813. doi: 10.1111/j.1365-2788.2008.01119_7.x

Pathogenetic mechanisms in Down Syndrome

2008

Journal Article

Human but not rat amylin shares neurotoxic properties with Aβ42 in long-term hippocampal and cortical cultures

Lim, Yun-An, Ittner, Lars M., Lim, Yun Li and Gotz, Jürgen (2008). Human but not rat amylin shares neurotoxic properties with Aβ42 in long-term hippocampal and cortical cultures. FEBS Letters, 582 (15), 2188-2194. doi: 10.1016/j.febslet.2008.05.006

Human but not rat amylin shares neurotoxic properties with Aβ42 in long-term hippocampal and cortical cultures

2008

Journal Article

Antiviral CD8 T cells recognize Borna disease virus antigen transgenically expressed in either neurons or astrocytes

Baur, Karen, Rauer, Mathias, Richter, Kirsten, Pagenstecher, Axel, Gotz, Jurgen, Hausmann, Jurgen and Staeheli, Peter (2008). Antiviral CD8 T cells recognize Borna disease virus antigen transgenically expressed in either neurons or astrocytes. Journal of Virology, 82 (6), 3099-3108. doi: 10.1128/JVI.02479-07

Antiviral CD8 T cells recognize Borna disease virus antigen transgenically expressed in either neurons or astrocytes

2008

Journal Article

Oligomeric and fibrillar species of β-amyloid (Aβ42) both impair mitochondrial function in P301L tau transgenic mice

Eckert, Anne, Hauptmann, Susanne, Scherping, Isabel, Meinhardt, Jessica, Rhein, Virginie, Drose, Stefan, Brandt, Ulrich, Fandrich, Marcus, Muller, Walter E. and Gotz, Jürgen (2008). Oligomeric and fibrillar species of β-amyloid (Aβ42) both impair mitochondrial function in P301L tau transgenic mice. Journal of Molecular Medicine, 86 (11), 1255-1267. doi: 10.1007/s00109-008-0391-6

Oligomeric and fibrillar species of β-amyloid (Aβ42) both impair mitochondrial function in P301L tau transgenic mice

2008

Journal Article

Animal models of Alzheimer's disease and frontotemporal dementia

Gotz, Jurgen and Ittner, Lars M. (2008). Animal models of Alzheimer's disease and frontotemporal dementia. Nature Reviews Neuroscience, 9 (7), 532-544. doi: 10.1038/nrn2420

Animal models of Alzheimer's disease and frontotemporal dementia

2008

Journal Article

Divergent phosphorylation pattern of tau in P301L tau transgenic mice

Deters, Natasha, Ittner, Lars M. and Gotz, Jurgen (2008). Divergent phosphorylation pattern of tau in P301L tau transgenic mice. European Journal of Neuroscience, 28 (1), 137-147. doi: 10.1111/j.1460-9568.2008.06318.x

Divergent phosphorylation pattern of tau in P301L tau transgenic mice

2008

Journal Article

Transgenic mice with ocular overexpression of an adrenomedullin receptor reflect human acute angle-closure glaucoma

Ittner, Lars M., Schwerdtfeger, Kerstin, Kunz, Thomas H., Muff, Roman, Husmann, Knut, Grimm, Christian, Hafezi, Farhad, Langh, Karl S., Kurrer, Michael O., Gotz, Jurgen, Born, Walter and Fischer, Jan A. (2008). Transgenic mice with ocular overexpression of an adrenomedullin receptor reflect human acute angle-closure glaucoma. Clinical Science, 114 (1-2), 49-58. doi: 10.1042/CS20070163

Transgenic mice with ocular overexpression of an adrenomedullin receptor reflect human acute angle-closure glaucoma

2008

Journal Article

Is tau aggregation toxic or protective: a sensible question in the absence of sensitive methods?

Goetz, Juergen, Ittner, Lars M., Faendrich, Marcus and Schonrock, Nicole (2008). Is tau aggregation toxic or protective: a sensible question in the absence of sensitive methods?. Journal of Alzheimers Disease, 14 (4), 423-429. doi: 10.3233/JAD-2008-14410

Is tau aggregation toxic or protective: a sensible question in the absence of sensitive methods?

2008

Journal Article

Neuroproteomics as a promising tool in Parkinson's disease research

Pienaar, Ilse S., Daniels, William M. U. and Gotz, Jurgen (2008). Neuroproteomics as a promising tool in Parkinson's disease research. Journal of Neural Transmission, 115 (10), 1413-1430. doi: 10.1007/s00702-008-0070-3

Neuroproteomics as a promising tool in Parkinson's disease research

2007

Journal Article

Directed selection of a conformational antibody domain that prevents mature amyloid fibril formation by stabilizing Aβ protofibrils

Habicht G., Haupt C., Friedrich R.P., Hortschansky P., Sachse C., Meinhardt J., Wieligmann K., Gellermann G.P., Brodhun M., Gotz J., Halbhuber K.-J., Rocken C., Horn U. and Fandrich M. (2007). Directed selection of a conformational antibody domain that prevents mature amyloid fibril formation by stabilizing Aβ protofibrils. Proceedings of the National Academy of Sciences of the United States of America, 104 (49), 19232-19237. doi: 10.1073/pnas.0703793104

Directed selection of a conformational antibody domain that prevents mature amyloid fibril formation by stabilizing Aβ protofibrils

2007

Journal Article

Aβ treatment and P301L tau expression in an Alzheimer's disease tissue culture model act synergistically to promote aberrant cell cycle re-entry

Hoerndli, Frederic J., Pelech, Steven, Papassotiropoulos, Andreas and Gotz, Juergen (2007). Aβ treatment and P301L tau expression in an Alzheimer's disease tissue culture model act synergistically to promote aberrant cell cycle re-entry. European Journal of Neuroscience, 26 (1), 60-72. doi: 10.1111/j.1460-9568.2007.05618.x

Aβ treatment and P301L tau expression in an Alzheimer's disease tissue culture model act synergistically to promote aberrant cell cycle re-entry