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2010

Journal Article

Parkinson's disease: insights from non-traditional model organisms

Pienaar, Ilse S., Gotz, Jürgen and Feany, Mel B. (2010). Parkinson's disease: insights from non-traditional model organisms. Progress in Neurobiology, 92 (4), 558-571. doi: 10.1016/j.pneurobio.2010.09.001

Parkinson's disease: insights from non-traditional model organisms

2010

Journal Article

Aβ and human amylin share a common toxicity pathway via mitochondrial dysfunction

Lim, Yun-An, Rhein, Virginie, Baysang, Ginette, Meier, Fides, Poljak, Anne, Raftery, Mark J., Guilhaus, Michael, Ittner, Lars M., Eckert, Anne and Gotz, Jürgen (2010). Aβ and human amylin share a common toxicity pathway via mitochondrial dysfunction. Proteomics, 10 (8), 1621-1633. doi: 10.1002/pmic.200900651

Aβ and human amylin share a common toxicity pathway via mitochondrial dysfunction

2009

Journal Article

Animal models for Alzheimer's disease and frontotemporal dementia: A perspective

Götz, Jürgen and Götz, Naeman N. (2009). Animal models for Alzheimer's disease and frontotemporal dementia: A perspective. ASN Neuro, 1 (4) e00019, 251-264. doi: 10.1042/AN20090042

Animal models for Alzheimer's disease and frontotemporal dementia: A perspective

2009

Journal Article

Amyloid-β and tau synergistically impair the oxidative phosphorylation system in triple transgenic Alzheimer's disease mice

Rhein, Virginie, Song, Xiaomin, Wiesner, Andreas, Ittner, Lars M., Baysang, Ginette, Meier, Fides, Ozmen, Laurence, Bluethmann, Horst, Drose, Stefan, Brandt, Ulrich, Savaskan, Egemen, Czech, Christian, Gotz, Jurgen and Eckert, Anne (2009). Amyloid-β and tau synergistically impair the oxidative phosphorylation system in triple transgenic Alzheimer's disease mice. Proceedings of the National Academy of Sciences of the United States of America, 106 (47), 20057-20062. doi: 10.1073/pnas.0905529106

Amyloid-β and tau synergistically impair the oxidative phosphorylation system in triple transgenic Alzheimer's disease mice

2009

Journal Article

Experimental diabetes mellitus exacerbates Tau pathology in a transgenic mouse model of Alzheimer's disease

Ke, Yazi D., Delerue, Fabien, Gladbach, Amadeus, Gotz, Jurgen and Ittner, Lars M. (2009). Experimental diabetes mellitus exacerbates Tau pathology in a transgenic mouse model of Alzheimer's disease. PLoS ONE, 4 (11) e7917, e7917.1-e7917.7. doi: 10.1371/journal.pone.0007917

Experimental diabetes mellitus exacerbates Tau pathology in a transgenic mouse model of Alzheimer's disease

2009

Journal Article

Response to the comment 'Iron, type 2 diabetes mellitus, and Alzheimer's disease' to our Visions and Reflections article 'Common features between diabetes mellitus and Alzheimer's disease'

Götz, Jürgen, Ittner, Lars M. and Lim, Yun-An (2009). Response to the comment 'Iron, type 2 diabetes mellitus, and Alzheimer's disease' to our Visions and Reflections article 'Common features between diabetes mellitus and Alzheimer's disease'. Cellular and Molecular Life Sciences, 66 (17), 2945-2945. doi: 10.1007/s00018-009-0073-8

Response to the comment 'Iron, type 2 diabetes mellitus, and Alzheimer's disease' to our Visions and Reflections article 'Common features between diabetes mellitus and Alzheimer's disease'

2009

Journal Article

Phosphorylated Tau interacts with c-Jun N-terminal kinase-interacting protein 1 (JIP1) in Alzheimer disease

Ittner, Lars M., Ke, Yazi D. and Gotz, Jurgen (2009). Phosphorylated Tau interacts with c-Jun N-terminal kinase-interacting protein 1 (JIP1) in Alzheimer disease. Journal of Biological Chemistry, 284 (31), 20909-20916. doi: 10.1074/jbc.M109.014472

Phosphorylated Tau interacts with c-Jun N-terminal kinase-interacting protein 1 (JIP1) in Alzheimer disease

2009

Journal Article

Common features between diabetes mellitus and Alzheimer's disease

Götz, J., Ittner, L. M. and Lim, Y. A. (2009). Common features between diabetes mellitus and Alzheimer's disease. Cellular and Molecular Life Sciences, 66 (8), 1321-1325. doi: 10.1007/s00018-009-9070-1

Common features between diabetes mellitus and Alzheimer's disease

2009

Journal Article

Substrate-specific reduction of PP2A activity exaggerates tau pathology

Deters, Natasha, Ittner, Lars M. and Gotz, Jurgen (2009). Substrate-specific reduction of PP2A activity exaggerates tau pathology. Biochemical and Biophysical Research Communications, 379 (2), 400-405. doi: 10.1016/j.bbrc.2008.12.140

Substrate-specific reduction of PP2A activity exaggerates tau pathology

2009

Journal Article

Phosphorylation of soluble tau differs in Pick's disease and Alzheimer's disease brains

van Eersel, Janet, Bi, Mian, Ke, Yazi D., Hodges, John R., Xuereb, John H., Gregory, Gillian C., Halliday, Glenda M., Gotz, Jurgen, Kril, Jillian J. and Ittner, Lars M. (2009). Phosphorylation of soluble tau differs in Pick's disease and Alzheimer's disease brains. Journal of Neural Transmission, 116 (10), 1243-1251. doi: 10.1007/s00702-009-0293-y

Phosphorylation of soluble tau differs in Pick's disease and Alzheimer's disease brains

2009

Journal Article

Primary support cultures of hippocampal and substantia nigra neurons

Fath, Thomas, Ke, Yazi D., Gunning, Peter, Gotz, Jürgen and Ittner, Lars M. (2009). Primary support cultures of hippocampal and substantia nigra neurons. Nature Protocols, 4 (1), 78-85. doi: 10.1038/nprot.2008.199

Primary support cultures of hippocampal and substantia nigra neurons

2009

Journal Article

Alzheimer's disease selective vulnerability and modeling in transgenic Mice

Gotz, Jurgen, Schonrock, Nicole, Vissel, Bryce and Ittner, Lars M. (2009). Alzheimer's disease selective vulnerability and modeling in transgenic Mice. Journal of Alzheimer's Disease, 18 (2), 243-251. doi: 10.3233/JAD-2009-1143

Alzheimer's disease selective vulnerability and modeling in transgenic Mice

2008

Journal Article

An update on the toxicity of A-beta in Alzheimer's disease

Götz, Jurgen, Ittner, Lars M, Schonrock, Nicole and Cappai, Roberto (2008). An update on the toxicity of A-beta in Alzheimer's disease. Neuropsychiatric Disease and Treatment, 4 (6), 1033-1042. doi: 10.2147/NDT.S3016

An update on the toxicity of A-beta in Alzheimer's disease

2008

Journal Article

Parkinsonism and impaired axonal transport in a mouse model of frontotemporal dementia

Ittner, Lars M., Fath, Thomas, Ke, Yazi D., Bi, Mian, van Eersel, Janet, Li, Kong M., Gunning, Peter and Gotz, Jurgen (2008). Parkinsonism and impaired axonal transport in a mouse model of frontotemporal dementia. Proceedings of the National Academy of Sciences of the United States of America, 105 (41), 15997-16002. doi: 10.1073/pnas.0808084105

Parkinsonism and impaired axonal transport in a mouse model of frontotemporal dementia

2008

Journal Article

Pathogenetic mechanisms in Down Syndrome

Einfeld, S., Goetz, J. and Holsinger, R. M. D. (2008). Pathogenetic mechanisms in Down Syndrome. Journal of Intellectual Disability Research, 52 (10), 813-813. doi: 10.1111/j.1365-2788.2008.01119_7.x

Pathogenetic mechanisms in Down Syndrome

2008

Journal Article

Human but not rat amylin shares neurotoxic properties with Aβ42 in long-term hippocampal and cortical cultures

Lim, Yun-An, Ittner, Lars M., Lim, Yun Li and Gotz, Jürgen (2008). Human but not rat amylin shares neurotoxic properties with Aβ42 in long-term hippocampal and cortical cultures. FEBS Letters, 582 (15), 2188-2194. doi: 10.1016/j.febslet.2008.05.006

Human but not rat amylin shares neurotoxic properties with Aβ42 in long-term hippocampal and cortical cultures

2008

Journal Article

Antiviral CD8 T cells recognize Borna disease virus antigen transgenically expressed in either neurons or astrocytes

Baur, Karen, Rauer, Mathias, Richter, Kirsten, Pagenstecher, Axel, Gotz, Jurgen, Hausmann, Jurgen and Staeheli, Peter (2008). Antiviral CD8 T cells recognize Borna disease virus antigen transgenically expressed in either neurons or astrocytes. Journal of Virology, 82 (6), 3099-3108. doi: 10.1128/JVI.02479-07

Antiviral CD8 T cells recognize Borna disease virus antigen transgenically expressed in either neurons or astrocytes

2008

Journal Article

Oligomeric and fibrillar species of β-amyloid (Aβ42) both impair mitochondrial function in P301L tau transgenic mice

Eckert, Anne, Hauptmann, Susanne, Scherping, Isabel, Meinhardt, Jessica, Rhein, Virginie, Drose, Stefan, Brandt, Ulrich, Fandrich, Marcus, Muller, Walter E. and Gotz, Jürgen (2008). Oligomeric and fibrillar species of β-amyloid (Aβ42) both impair mitochondrial function in P301L tau transgenic mice. Journal of Molecular Medicine, 86 (11), 1255-1267. doi: 10.1007/s00109-008-0391-6

Oligomeric and fibrillar species of β-amyloid (Aβ42) both impair mitochondrial function in P301L tau transgenic mice

2008

Journal Article

Animal models of Alzheimer's disease and frontotemporal dementia

Gotz, Jurgen and Ittner, Lars M. (2008). Animal models of Alzheimer's disease and frontotemporal dementia. Nature Reviews Neuroscience, 9 (7), 532-544. doi: 10.1038/nrn2420

Animal models of Alzheimer's disease and frontotemporal dementia

2008

Journal Article

Divergent phosphorylation pattern of tau in P301L tau transgenic mice

Deters, Natasha, Ittner, Lars M. and Gotz, Jurgen (2008). Divergent phosphorylation pattern of tau in P301L tau transgenic mice. European Journal of Neuroscience, 28 (1), 137-147. doi: 10.1111/j.1460-9568.2008.06318.x

Divergent phosphorylation pattern of tau in P301L tau transgenic mice