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2009 Journal Article Animal models for Alzheimer's disease and frontotemporal dementia: A perspectiveGötz, Jürgen and Götz, Naeman N. (2009). Animal models for Alzheimer's disease and frontotemporal dementia: A perspective. ASN Neuro, 1 (4) e00019, 251-264. doi: 10.1042/AN20090042 |
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2009 Journal Article Amyloid-β and tau synergistically impair the oxidative phosphorylation system in triple transgenic Alzheimer's disease miceRhein, Virginie, Song, Xiaomin, Wiesner, Andreas, Ittner, Lars M., Baysang, Ginette, Meier, Fides, Ozmen, Laurence, Bluethmann, Horst, Drose, Stefan, Brandt, Ulrich, Savaskan, Egemen, Czech, Christian, Gotz, Jurgen and Eckert, Anne (2009). Amyloid-β and tau synergistically impair the oxidative phosphorylation system in triple transgenic Alzheimer's disease mice. Proceedings of the National Academy of Sciences of the United States of America, 106 (47), 20057-20062. doi: 10.1073/pnas.0905529106 |
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2009 Journal Article Experimental diabetes mellitus exacerbates Tau pathology in a transgenic mouse model of Alzheimer's diseaseKe, Yazi D., Delerue, Fabien, Gladbach, Amadeus, Gotz, Jurgen and Ittner, Lars M. (2009). Experimental diabetes mellitus exacerbates Tau pathology in a transgenic mouse model of Alzheimer's disease. PLoS ONE, 4 (11) e7917, e7917.1-e7917.7. doi: 10.1371/journal.pone.0007917 |
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2009 Journal Article Response to the comment 'Iron, type 2 diabetes mellitus, and Alzheimer's disease' to our Visions and Reflections article 'Common features between diabetes mellitus and Alzheimer's disease'Götz, Jürgen, Ittner, Lars M. and Lim, Yun-An (2009). Response to the comment 'Iron, type 2 diabetes mellitus, and Alzheimer's disease' to our Visions and Reflections article 'Common features between diabetes mellitus and Alzheimer's disease'. Cellular and Molecular Life Sciences, 66 (17), 2945-2945. doi: 10.1007/s00018-009-0073-8 |
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2009 Journal Article Phosphorylated Tau interacts with c-Jun N-terminal kinase-interacting protein 1 (JIP1) in Alzheimer diseaseIttner, Lars M., Ke, Yazi D. and Gotz, Jurgen (2009). Phosphorylated Tau interacts with c-Jun N-terminal kinase-interacting protein 1 (JIP1) in Alzheimer disease. Journal of Biological Chemistry, 284 (31), 20909-20916. doi: 10.1074/jbc.M109.014472 |
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2009 Journal Article Common features between diabetes mellitus and Alzheimer's diseaseGötz, J., Ittner, L. M. and Lim, Y. A. (2009). Common features between diabetes mellitus and Alzheimer's disease. Cellular and Molecular Life Sciences, 66 (8), 1321-1325. doi: 10.1007/s00018-009-9070-1 |
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2009 Journal Article Substrate-specific reduction of PP2A activity exaggerates tau pathologyDeters, Natasha, Ittner, Lars M. and Gotz, Jurgen (2009). Substrate-specific reduction of PP2A activity exaggerates tau pathology. Biochemical and Biophysical Research Communications, 379 (2), 400-405. doi: 10.1016/j.bbrc.2008.12.140 |
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2009 Journal Article Phosphorylation of soluble tau differs in Pick's disease and Alzheimer's disease brainsvan Eersel, Janet, Bi, Mian, Ke, Yazi D., Hodges, John R., Xuereb, John H., Gregory, Gillian C., Halliday, Glenda M., Gotz, Jurgen, Kril, Jillian J. and Ittner, Lars M. (2009). Phosphorylation of soluble tau differs in Pick's disease and Alzheimer's disease brains. Journal of Neural Transmission, 116 (10), 1243-1251. doi: 10.1007/s00702-009-0293-y |
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2009 Journal Article Primary support cultures of hippocampal and substantia nigra neuronsFath, Thomas, Ke, Yazi D., Gunning, Peter, Gotz, Jürgen and Ittner, Lars M. (2009). Primary support cultures of hippocampal and substantia nigra neurons. Nature Protocols, 4 (1), 78-85. doi: 10.1038/nprot.2008.199 |
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2009 Journal Article Alzheimer's disease selective vulnerability and modeling in transgenic MiceGotz, Jurgen, Schonrock, Nicole, Vissel, Bryce and Ittner, Lars M. (2009). Alzheimer's disease selective vulnerability and modeling in transgenic Mice. Journal of Alzheimer's Disease, 18 (2), 243-251. doi: 10.3233/JAD-2009-1143 |
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2008 Journal Article An update on the toxicity of A-beta in Alzheimer's diseaseGötz, Jurgen, Ittner, Lars M, Schonrock, Nicole and Cappai, Roberto (2008). An update on the toxicity of A-beta in Alzheimer's disease. Neuropsychiatric Disease and Treatment, 4 (6), 1033-1042. doi: 10.2147/NDT.S3016 |
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2008 Journal Article Parkinsonism and impaired axonal transport in a mouse model of frontotemporal dementiaIttner, Lars M., Fath, Thomas, Ke, Yazi D., Bi, Mian, van Eersel, Janet, Li, Kong M., Gunning, Peter and Gotz, Jurgen (2008). Parkinsonism and impaired axonal transport in a mouse model of frontotemporal dementia. Proceedings of the National Academy of Sciences of the United States of America, 105 (41), 15997-16002. doi: 10.1073/pnas.0808084105 |
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2008 Journal Article Pathogenetic mechanisms in Down SyndromeEinfeld, S., Goetz, J. and Holsinger, R. M. D. (2008). Pathogenetic mechanisms in Down Syndrome. Journal of Intellectual Disability Research, 52 (10), 813-813. doi: 10.1111/j.1365-2788.2008.01119_7.x |
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2008 Journal Article Human but not rat amylin shares neurotoxic properties with Aβ42 in long-term hippocampal and cortical culturesLim, Yun-An, Ittner, Lars M., Lim, Yun Li and Gotz, Jürgen (2008). Human but not rat amylin shares neurotoxic properties with Aβ42 in long-term hippocampal and cortical cultures. FEBS Letters, 582 (15), 2188-2194. doi: 10.1016/j.febslet.2008.05.006 |
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2008 Journal Article Antiviral CD8 T cells recognize Borna disease virus antigen transgenically expressed in either neurons or astrocytesBaur, Karen, Rauer, Mathias, Richter, Kirsten, Pagenstecher, Axel, Gotz, Jurgen, Hausmann, Jurgen and Staeheli, Peter (2008). Antiviral CD8 T cells recognize Borna disease virus antigen transgenically expressed in either neurons or astrocytes. Journal of Virology, 82 (6), 3099-3108. doi: 10.1128/JVI.02479-07 |
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2008 Journal Article Oligomeric and fibrillar species of β-amyloid (Aβ42) both impair mitochondrial function in P301L tau transgenic miceEckert, Anne, Hauptmann, Susanne, Scherping, Isabel, Meinhardt, Jessica, Rhein, Virginie, Drose, Stefan, Brandt, Ulrich, Fandrich, Marcus, Muller, Walter E. and Gotz, Jürgen (2008). Oligomeric and fibrillar species of β-amyloid (Aβ42) both impair mitochondrial function in P301L tau transgenic mice. Journal of Molecular Medicine, 86 (11), 1255-1267. doi: 10.1007/s00109-008-0391-6 |
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2008 Journal Article Animal models of Alzheimer's disease and frontotemporal dementiaGotz, Jurgen and Ittner, Lars M. (2008). Animal models of Alzheimer's disease and frontotemporal dementia. Nature Reviews Neuroscience, 9 (7), 532-544. doi: 10.1038/nrn2420 |
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2008 Journal Article Divergent phosphorylation pattern of tau in P301L tau transgenic miceDeters, Natasha, Ittner, Lars M. and Gotz, Jurgen (2008). Divergent phosphorylation pattern of tau in P301L tau transgenic mice. European Journal of Neuroscience, 28 (1), 137-147. doi: 10.1111/j.1460-9568.2008.06318.x |
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2008 Journal Article Transgenic mice with ocular overexpression of an adrenomedullin receptor reflect human acute angle-closure glaucomaIttner, Lars M., Schwerdtfeger, Kerstin, Kunz, Thomas H., Muff, Roman, Husmann, Knut, Grimm, Christian, Hafezi, Farhad, Langh, Karl S., Kurrer, Michael O., Gotz, Jurgen, Born, Walter and Fischer, Jan A. (2008). Transgenic mice with ocular overexpression of an adrenomedullin receptor reflect human acute angle-closure glaucoma. Clinical Science, 114 (1-2), 49-58. doi: 10.1042/CS20070163 |
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2008 Journal Article Is tau aggregation toxic or protective: a sensible question in the absence of sensitive methods?Goetz, Juergen, Ittner, Lars M., Faendrich, Marcus and Schonrock, Nicole (2008). Is tau aggregation toxic or protective: a sensible question in the absence of sensitive methods?. Journal of Alzheimers Disease, 14 (4), 423-429. doi: 10.3233/JAD-2008-14410 |
