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2013 Journal Article PTL-1 regulates neuronal integrity and lifespan in C-elegansChew, Yee Lian, Fan, Xiaochen, Goetz, Juergen and Nicholas, Hannah R. (2013). PTL-1 regulates neuronal integrity and lifespan in C-elegans. Journal of Cell Science, 126 (9), 2079-2091. doi: 10.1242/jcs.jcs124404 |
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2013 Journal Article Pattern of tau hyperphosphorylation and neurotransmitter markers in the brainstem of senescent tau filament forming transgenic miceMorcinek, Kerstin, Köhler, Christoph, Goetz, Juergen and Schröder, Hannsjorg (2013). Pattern of tau hyperphosphorylation and neurotransmitter markers in the brainstem of senescent tau filament forming transgenic mice. Brain Research, 1497, 73-84. doi: 10.1016/j.brainres.2012.12.016 |
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2013 Journal Article How it all started: Tau and protein phosphatase 2ALiu, Chang and Goetz, Juergen (2013). How it all started: Tau and protein phosphatase 2A. Journal of Alzheimer's Disease, 37 (3), 483-494. doi: 10.3233/jad-130503 |
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2013 Journal Article Single nucleotide variants (SNVs) define senescence-accelerated SAMP8 mice, a model of a geriatric conditionDelerue, Fabien, Sjollema, Geoff, Whittle, Belinda, Krueger, Sarah, Andrews, Dan and Goetz, Juergen (2013). Single nucleotide variants (SNVs) define senescence-accelerated SAMP8 mice, a model of a geriatric condition. Journal of Alzheimers Disease, 36 (2), 349-363. doi: 10.3233/JAD-130089 |
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2012 Journal Article Decoding the non-coding RNAs in Alzheimer's diseaseSchonrock, Nicole and Goetz, Juergen (2012). Decoding the non-coding RNAs in Alzheimer's disease. Cellular and Molecular Life Sciences, 69 (21), 3543-3559. doi: 10.1007/s00018-012-1125-z |
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2012 Journal Article Tau promotes neurodegeneration via DRP1 mislocalization in vivoDuBoff, Brian, Goetz, Juergen and Feany, Mel B. (2012). Tau promotes neurodegeneration via DRP1 mislocalization in vivo. Neuron, 75 (4), 618-632. doi: 10.1016/j.neuron.2012.06.026 |
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2012 Journal Article Alzheimer's disease models and functional genomics-how many needles are there in the haystack?Goetz, Juergen, Matamales, Miriam, Goetz, Naeman N., Ittner, Lars M. and Eckert, Anne (2012). Alzheimer's disease models and functional genomics-how many needles are there in the haystack?. Frontiers in Physiology, 3 (320) Article 320, 320.1-320.14. doi: 10.3389/fphys.2012.00320 |
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2012 Journal Article Alzheimer's disease, oestrogen and mitochondria: an ambiguous relationshipGrimm, Amandine, Lim, Yun-An, Mensah-Nyagan, Ayikoe Guy, Goetz, Jurgen and Eckert, Anne (2012). Alzheimer's disease, oestrogen and mitochondria: an ambiguous relationship. Molecular Neurobiology, 46 (1), 151-160. doi: 10.1007/s12035-012-8281-x |
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2012 Journal Article MicroRNA networks surrounding APP and amyloid-β metabolism - implications for Alzheimer's diseaseSchonrock, Nicole, Matamales, Miriam, Ittner, Lars M. and Gotz, Juergen (2012). MicroRNA networks surrounding APP and amyloid-β metabolism - implications for Alzheimer's disease. Experimental Neurology, 235 (2), 447-454. doi: 10.1016/j.expneurol.2011.11.013 |
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2012 Journal Article Tau-mediated nuclear depletion and cytoplasmic accumulation of SFPQ in Alzheimer's and Pick's diseaseKe, Yazi, Dramiga, Joe, Schütz, Ulrich, Kril, Jillian J., Ittner, Lars M., Schröder, Hannsjörg and Götz, Jürgen (2012). Tau-mediated nuclear depletion and cytoplasmic accumulation of SFPQ in Alzheimer's and Pick's disease. PloS One, 7 (4), 1-8. doi: 10.1371/journal.pone.0035678 |
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2012 Journal Article Insights into mitochondrial dysfunction: aging, amyloid-β, and tau-A deleterious trioSchmitt, Karen, Grimm, Amandine, Kazmierczak, Anna, Strosznajder, Joanna B., Gotz, Jurgen and Eckert, Anne (2012). Insights into mitochondrial dysfunction: aging, amyloid-β, and tau-A deleterious trio. Antioxidants and Redox Signaling, 16 (12), 1456-1466. doi: 10.1089/ars.2011.4400 |
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2012 Journal Article A neuroprotective role for the DNA damage checkpoint in tauopathyKhurana, Vikram, Merlo, Paola, DuBoff, Brian, Fulga, Tudor A., Sharp, Katherine A., Campbell, Shelagh D., Goetz, Juergen and Feany, Mel B. (2012). A neuroprotective role for the DNA damage checkpoint in tauopathy. Aging Cell, 11 (2), 360-362. doi: 10.1111/j.1474-9726.2011.00778.x |
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2012 Journal Article Tau-targeted treatment strategies in Alzheimer's diseaseGotz, Jurgen, Ittner, Arne and Ittner, Lars M. (2012). Tau-targeted treatment strategies in Alzheimer's disease. British Journal of Pharmacology, 165 (5), 1246-1259. doi: 10.1111/j.1476-5381.2011.01713.x |
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2012 Journal Article Target gene repression mediated by miRNAs miR-181c and miR-9 both of which are down-regulated by amyloid-β.Schonrock, Nicole, Humphreys, David T., Preiss, Thomas and Gotz, Jürgen (2012). Target gene repression mediated by miRNAs miR-181c and miR-9 both of which are down-regulated by amyloid-β.. Journal of Molecular Neuroscience, 46 (2), 324-335. doi: 10.1007/s12031-011-9587-2 |
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2012 Journal Article Role of hippocalcin in mediating Aβ toxicityLim, Yun-An, Giese, Maria, Shepherd, Claire, Halliday, Glenda, Kobayashi, Masaaki, Takamatsu, Ken, Staufenbiel, Matthias, Eckert, Anne and Gotz, Jürgen (2012). Role of hippocalcin in mediating Aβ toxicity. Biochimica et Biophysica Acta - Molecular Basis of Disease, 1822 (8), 1247-1257. doi: 10.1016/j.bbadis.2012.04.007 |
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2011 Journal Article Tau-targeted immunization impedes progression of neurofibrillary histopathology in aged P301L tau transgenic miceBi, Mian, Ittner, Arne, Ke, Yazi D., Gotz, Jurgen and Ittner, Lars M. (2011). Tau-targeted immunization impedes progression of neurofibrillary histopathology in aged P301L tau transgenic mice. PLoS ONE, 6 (12) e26860, e26860.1-e26860.7. doi: 10.1371/journal.pone.0026860 |
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2011 Journal Article Inhibition of the mitochondrial enzyme ABAD restores the amyloid-β-mediated deregulation of estradiolLim, Yun-An, Grimm, Amandine, Giese, Maria, Mensah-Nyagan, Ayikoe Guy, Villafranca, J. Ernest, Ittner, Lars M., Eckert, Anne and Gotz, Jurgen (2011). Inhibition of the mitochondrial enzyme ABAD restores the amyloid-β-mediated deregulation of estradiol. PLoS ONE, 6 (12) e28887, e28887.1-e28887.12. doi: 10.1371/journal.pone.0028887 |
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2011 Journal Article Alzheimer's disease selective vulnerability and modelling in transgenic miceGötz, Jürgen, Schonrock, Nicole, Vissel, Bryce and Ittner, Lars M. (2011). Alzheimer's disease selective vulnerability and modelling in transgenic mice. Advances in Alzheimer's Disease, 1, 49-58. doi: 10.3233/978-1-60750-733-8-49 |
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2011 Journal Article Cytoplasmic accumulation and aggregation of TDP-43 upon proteasome inhibition in cultured neuronsvan Eersel, Janet, Ke, Yazi D., Gladbach, Amadeus, Bi, Mian, Gotz, Jurgen, Kril, Jillian J. and Ittner, Lars M. (2011). Cytoplasmic accumulation and aggregation of TDP-43 upon proteasome inhibition in cultured neurons. PLoS ONE, 6 (7) e22850, e22850.1-e22850.13. doi: 10.1371/journal.pone.0022850 |
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2011 Journal Article Mitochondrial dysfunction - The beginning of the end in Alzheimer's disease? Separate and synergistic modes of tau and amyloid-toxicityEckert, Anne, Schmitt, Karen and Gotz, Jurgen (2011). Mitochondrial dysfunction - The beginning of the end in Alzheimer's disease? Separate and synergistic modes of tau and amyloid-toxicity. Alzheimer's Research and Therapy, 3 (3) 15, 15.1-15.11. doi: 10.1186/alzrt74 |
