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2011 Journal Article Langerhans cells are precommitted to immune tolerance inductionShklovskaya, Elena, O'Sullivan, Brendan J., Ng, Lai Guan, Roediger, Ben, Thomas, Ranjeny, Weninger, Wolfgang and de St Groth, Barbara Fazekas (2011). Langerhans cells are precommitted to immune tolerance induction. Proceedings of the National Academy of Sciences of the United States of America, 108 (44), 18049-18054. doi: 10.1073/pnas.1110076108 |
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2011 Journal Article Targeting curcusomes to inflammatory dendritic cells inhibits NF-{kappa}b and improves insulin resistance in obese miceYekollu, Suman Kumar, Thomas, Ranjeny and O'Sullivan, Brendan (2011). Targeting curcusomes to inflammatory dendritic cells inhibits NF-{kappa}b and improves insulin resistance in obese mice. Diabetes, 60 (11), 2928-2938. doi: 10.2337/db11-0275 |
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2011 Journal Article Immunotherapy with costimulatory dendritic cells to control autoimmune inflammationO'Sullivan, Brendan J., Pai, Saparna, Street, Shayna, An, Xiayou, Macdonald, Kelli P. A., Wong, Michelle, Strutton, Geoffrey, Gerondakis, Steve, Steptoe, Raymond J., Fazekas de St Groth, Barbara, Hill, Geoffrey R. and Thomas, Ranjeny (2011). Immunotherapy with costimulatory dendritic cells to control autoimmune inflammation. Journal of Immunology, 187 (7), 4018-4030. doi: 10.4049/jimmunol.1101727 |
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2011 Journal Article CD4+CD25+ regulatory T cells control CD8+ T-cell effector differentiation by modulating IL-2 homeostasisMcNally, Alice, Hill, Geoffrey R., Sparwasser, Tim, Thomas, Ranjeny and Steptoe, Raymond J. (2011). CD4+CD25+ regulatory T cells control CD8+ T-cell effector differentiation by modulating IL-2 homeostasis. Proceedings of the National Academy of Sciences of the United States of America, 108 (18), 7529-7534. doi: 10.1073/pnas.1103782108 |
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2011 Conference Publication PROINFLAMMATORY AND REGULATORY T CELL RESPONSES TO CITRULLINATED AUTOANTIGENIC PEPTIDES IN PERIPHERAL BLOOD OF SHARED EPITOPE plus RHEUMATOID ARTHRITIS PATIENTSStreet, S., Purcell, A., Law, S., Yu, A., Capini, C., O'Sullivan, B., Pahau, H. and Thomas, R. (2011). PROINFLAMMATORY AND REGULATORY T CELL RESPONSES TO CITRULLINATED AUTOANTIGENIC PEPTIDES IN PERIPHERAL BLOOD OF SHARED EPITOPE plus RHEUMATOID ARTHRITIS PATIENTS. MALDEN: WILEY-BLACKWELL. |
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2011 Journal Article Reduced soluble receptor for advanced glycation end-products in COPDSmith, D. J., Yerkovich, S. T., Towers, M. A., Carroll, M. L., Thomas, R. and Upham, J. W. (2011). Reduced soluble receptor for advanced glycation end-products in COPD. European Respiratory Journal, 37 (3), 516-522. doi: 10.1183/09031936.00029310 |
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2011 Conference Publication Feasibility, safety and clinical effects of a single intradermal administration of autologous tolerising dendritic cells exposed to citrullinated peptides in patients with rheumatoid arthritisThomas, Ranjeny, Street, Shayna, Ramnoruth, Nishta, Pahau, Helen, Law, Soi, Brunck, Marion, Hyde, Claire, O'Sullivan, Brendan, Capini, C., Tran, A., Ng, J. and Paul, S. (2011). Feasibility, safety and clinical effects of a single intradermal administration of autologous tolerising dendritic cells exposed to citrullinated peptides in patients with rheumatoid arthritis. 75th Annual Scientific Meeting of the American College of Rheumatology/46th Annual Scientific Meeting of the Association-of-Rheumatology-Health-Professionals, Chicago, IL, United States, 04-09 November 2011. Hoboken NJ, United States: John Wiley & Sons. doi: 10.1002/art.33310 |
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2011 Journal Article Interleukin-1 beta produced in response to islet autoantigen presentation differentiates T-helper 17 cells at the expense of regulatory T-cells: Implications for the timing of tolerizing immunotherapyBertin-Maghit, Sebastien, Pang, Dimeng, O'Sullivan, Brendan, Best, Shannon, Duggan, Emily, Paul, Sanjoy, Thomas, Helen, Kay, Thomas W. H., Harrison, Leonard C., Steptoe, Raymond and Thomas, Ranjeny (2011). Interleukin-1 beta produced in response to islet autoantigen presentation differentiates T-helper 17 cells at the expense of regulatory T-cells: Implications for the timing of tolerizing immunotherapy. Diabetes, 60 (1), 248-257. doi: 10.2337/db10-0104 |
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2011 Conference Publication The Role of Gut Microflora and Autoreactive CD4+T Cells in the Development of Spondyloarthritis and Inflammatory Bowel Disease in Beta-Glucan-Treated SKG MiceRuutu, Merja, Velasco, Jared, Aguirre, Daniel, Benham, Helen, Morrison, Mark, McGuckin, Michael and Thomas, Ranjeny (2011). The Role of Gut Microflora and Autoreactive CD4+T Cells in the Development of Spondyloarthritis and Inflammatory Bowel Disease in Beta-Glucan-Treated SKG Mice. 75th Annual Scientific Meeting of the American College of Rheumatology/46th Annual Scientific Meeting of the Association of Rheumatology Health Professionals, Chicago, IL, United States, 4-9 November 2011. Hoboken, NJ, United States: John Wiley & Sons. doi: 10.1002/art.33310 |
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2011 Journal Article Streptococcus pneumoniae infection suppresses allergic airways disease by inducing regulatory T-cellsPreston, J. A., Thorburn, A. N., Starkey, M. R., Beckett, E. L., Horvat, J. C., Wade, M. A., O'Sullivan, B. J., Thomas, R., Beagley, K. W., Gibson, P. G., Foster, P. S. and Hansbro, P. M. (2011). Streptococcus pneumoniae infection suppresses allergic airways disease by inducing regulatory T-cells. European Respiratory Journal, 37 (1), 53-64. doi: 10.1183/09031936.00049510 |
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2010 Journal Article Pneumococcal conjugate vaccine-induced regulatory T cells suppress the development of allergic airways diseaseThorburn, Alison N., O'Sullivan, Brendan J., Thomas, Ranjeny, Kumar, Rakesh K., Foster, Peter S., Gibson, Peter G. and Hansbro, Philip M. (2010). Pneumococcal conjugate vaccine-induced regulatory T cells suppress the development of allergic airways disease. Thorax, 65 (12), 1053-1060. doi: 10.1136/thx.2009.131508 |
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2010 Journal Article IL-1 signalling determines the fate of skin grafts expressing non-self protein in keratinocytesHadis, Usriansyah, Leggatt, Graham R., Thomas, Ranjeny, Frazer, Ian H. and Kovacs, Eva M. (2010). IL-1 signalling determines the fate of skin grafts expressing non-self protein in keratinocytes. Experimental Dermatology, 19 (8), 723-729. doi: 10.1111/j.1600-0625.2010.01092.x |
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2010 Journal Article c-Rel is required for the development of thymic Foxp3+ CD4 regulatory T cells (The Journal of Experimental Medicine (December 21, 2009) 206, 13 (3001-3014))Isomura, Iwao, Palmer, Stephanie, Grumont, Raelene J., Bunting, Karen, Hoyne, Gerard, Wilkinson, Nancy, Banerjee, Ashish, Proietto, Anna, Gugasyan, Raffi, Wu, Li, McNally, Alice, Steptoe, Raymond J., Thomas, Ranjeny, Shannon, M. Frances and Gerondakis, Steve (2010). c-Rel is required for the development of thymic Foxp3+ CD4 regulatory T cells (The Journal of Experimental Medicine (December 21, 2009) 206, 13 (3001-3014)). Journal of Experimental Medicine, 207 (4), 899-899. doi: 10.1084/jem.2009141132610c |
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2010 Journal Article c-Rel is required for the development of thymic Foxp3(+) CD4 regulatory T cells (vol 206, pg 3001, 2009)Isomura, Iwao, Palmer, Stephanie, Grumont, Raelene J., Bunting, Karen, Hoyne, Gerard, Wilkinson, Nancy, Banerjee, Ashish, Proietto, Anna, Gugasyan, Raffi, Wu, Li, McNally, Alice, Steptoe, Raymond J., Thomas, Ranjeny, Shannon, M. Frances and Gerondakis, Steve (2010). c-Rel is required for the development of thymic Foxp3(+) CD4 regulatory T cells (vol 206, pg 3001, 2009). Journal of Experimental Medicine, 207 (4) |
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2010 Journal Article The balancing act of autoimmunity: Central and peripheral tolerance versus infection controlThomas, Ranjeny (2010). The balancing act of autoimmunity: Central and peripheral tolerance versus infection control. International Reviews of Immunology, 29 (2), 211-233. doi: 10.3109/08830180903434219 |
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2010 Journal Article A physiological function of inflammation-associated SerpinB2 is regulation of adaptive immunitySchroder, Wayne A., Le, Thuy T. T., Major, Lee, Street, Shayna, Gardner, Joy, Lambley, Eleanore, Markey, Kate, MacDonald, Kelli P., Fish, Richard J., Thomas, Ranjeny and Suhrbier, Andreas (2010). A physiological function of inflammation-associated SerpinB2 is regulation of adaptive immunity. Journal of Immunology, 184 (5), 2663-2670. doi: 10.4049/jimmunol.0902187 |
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2010 Journal Article Targeting antigen to diverse APCs inactivates memory CD8+ T cells without eliciting tissue-destructive effector functionKenna, Tony J., Waldie, Tanya, McNally, Alice, Thomson, Meagan, Yagita, Hideo, Thomas, Ranjeny and Steptoe, Raymond J. (2010). Targeting antigen to diverse APCs inactivates memory CD8+ T cells without eliciting tissue-destructive effector function. Journal of Immunology, 184 (2), 598-606. doi: 10.4049/jimmunol.0900032 |
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2010 Conference Publication F.72. IL-1 beta produced in response to islet autoantigen presentation differentiates T-helper-17 cells at the expense of regulatory T cells: Implications for the timing of tolerizing immunotherapyBertin-Maghit, Sebastien, O'Sullivan, Brendan, Best, Shannoiin, Duggan, Emily, Pang, Dimeng, Thomas, Helen, Kay, Thomas, Harrison, Leonard, Steptoe, Raymond and Thomas, Ranjeny (2010). F.72. IL-1 beta produced in response to islet autoantigen presentation differentiates T-helper-17 cells at the expense of regulatory T cells: Implications for the timing of tolerizing immunotherapy. FOCiS 2010: Tenth Annual Meeting of the Federation of Clinical Immunology Societies, Boston, MA, U.S.A., 24-27 June 2010. Orlando, FL, U.S.A.: Academic Press. doi: 10.1016/j.clim.2010.03.294 |
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2010 Conference Publication Autoreactive T cells Eescaping thymic deletion in REL-B deficient mice depend on dendritic cell-encoded REL-B for control of autoimmunityO'Sullivan, B, Pai, S, Street, S, MacDonald, K, Gerondakis, S, Hill, G and Thomas, R (2010). Autoreactive T cells Eescaping thymic deletion in REL-B deficient mice depend on dendritic cell-encoded REL-B for control of autoimmunity. 10th Annual Meeting of the Federation-of-Clinical-Immunology-Societies, Boston, MA, U.S.A., 24-27 June 2010. Maryland Heights, MO, U.S.A.: Academic Press. doi: 10.1016/j.clim.2010.03.407 |
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2010 Conference Publication F.25. Activity of the REL-B and p65 subunits of NF-kappa B demonstrates innate immune activation in children at risk of type 1 diabetesPai, S, Best, S, Roddick, J, Pahao, H, Baskerville, T, Brown, M, Harris, M, Cotterill, A and Thomas, R (2010). F.25. Activity of the REL-B and p65 subunits of NF-kappa B demonstrates innate immune activation in children at risk of type 1 diabetes. FOCiS 2010: Tenth Annual Meeting of the Federation of Clinical Immunology Societies, Boston, MA, U.S.A., 24-27 June 2010. Orlando, FL, U.S.A.: Academic Press. doi: 10.1016/j.clim.2010.03.247 |
