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2018 Journal Article Self-adjuvanting nanoemulsion targeting dendritic cell receptor Clec9A enables antigen-specific immunotherapyZeng, Bijun, Middelberg, Anton P. J., Gemiarto, Adrian, MacDonald, Kelli, Baxter, Alan G, Talekar, Meghna, Moi, Davide, Tullett, Kirsteen M, Caminschi, Irina, Lahoud, Mireille H, Mazzieri, Roberta, Dolcetti, Riccardo and Thomas, Ranjeny (2018). Self-adjuvanting nanoemulsion targeting dendritic cell receptor Clec9A enables antigen-specific immunotherapy. The Journal of clinical investigation, 128 (5), 1971-1984. doi: 10.1172/JCI96791 |
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2018 Journal Article A peripheral blood transcriptomic signature predicts autoantibody development in infants at risk of type 1 diabetesMehdi, Ahmed M., Hamilton-Williams, Emma E., Cristino, Alexandre, Ziegler, Anette, Bonifacio, Ezio, Le Cao, Kim-Anh, Harris, Mark and Thomas, Ranjeny (2018). A peripheral blood transcriptomic signature predicts autoantibody development in infants at risk of type 1 diabetes. JCI Insight, 3 (5) e98212. doi: 10.1172/jci.insight.98212 |
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2017 Journal Article Molecular basis for increased susceptibility of Indigenous North Americans to seropositive rheumatoid arthritisScally, Stephen W, Law, Soi-Cheng, Ting, Yi Tian, Heemst, Jurgen Van, Sokolove, Jeremy, Deutsch, Aaron J, Bridie Clemens, E., Moustakas, Antonis K, Papadopoulos, George K, Woude, Diane Van Der, Smolik, Irene, Hitchon, Carol A, Robinson, David B, Ferucci, Elizabeth D, Bernstein, Charles N, Meng, Xiaobo, Anaparti, Vidyanand, Huizinga, Tom, Kedzierska, Katherine, Reid, Hugh H, Raychaudhuri, Soumya, Toes, René E, Rossjohn, Jamie, El-Gabalawy, Hani and Thomas, Ranjeny (2017). Molecular basis for increased susceptibility of Indigenous North Americans to seropositive rheumatoid arthritis. Annals of the Rheumatic Diseases, 76 (11), 1915-1923. doi: 10.1136/annrheumdis-2017-211300 |
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2015 Journal Article Citrullinated peptide dendritic cell immunotherapy in HLA risk genotype–positive rheumatoid arthritis patientsBenham, Helen, Nel, Hendrik J., Law, Soi Cheng, Mehdi, Ahmed M., Street, Shayna, Ramnoruth, Nishta, Pahau, Helen, Lee, Bernett T., Ng, Jennifer, Brunck, Marion E. G., Hyde, Claire, Trouw, Leendert A., Dudek, Nadine L., Purcell, Anthony W., O'Sullivan, Brendan J., Connolly, John E., Paul, Sanjoy K., Le Cao, Kim-Anh and Thomas, Ranjeny (2015). Citrullinated peptide dendritic cell immunotherapy in HLA risk genotype–positive rheumatoid arthritis patients. Science Translational Medicine, 7 (290) 290ra87, 290ra87.1-290ra87.11. doi: 10.1126/scitranslmed.aaa9301 |
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2015 Journal Article High Chlamydia burden promotes TNF-dependent reactive arthritis in SKG miceBaillet, Athan C., Rehaume, Linda, Benham, Helen, O'Meara, Connor P., Armitage, Charles W., Ruscher, Roland, Brizard, Geraldine, Harvie, Marina C. G., Velasco, Jared, Hansbro, Phillip, Forrester, John V., Degli-Esposti, Mariapia, Beagley, Kenneth W. and Thomas, Ranjeny (2015). High Chlamydia burden promotes TNF-dependent reactive arthritis in SKG mice. Arthritis and Rheumatology, 67 (6), 1535-1547. doi: 10.1002/art.39041 |
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2014 Journal Article ZAP-70 genotype disrupts the relationship between microbiota and host leading to spondyloarthritis and ileitis in SKG MiceRehaume, Linda, Mondot, Stanislas, Aguirre de Cárcer, Daniel, Velasco, Jared, Benham, Helen, Hasnain, Sumaira Zia, Bowman, Jaclyn, Ruutu, Merja, Hansbro, Philip M., McGuckin, Michael, Morrison, Mark and Thomas, Ranjeny (2014). ZAP-70 genotype disrupts the relationship between microbiota and host leading to spondyloarthritis and ileitis in SKG Mice. Arthritis and Rheumatology, 66 (10), 2780-2792. doi: 10.1002/art.38773 |
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2014 Journal Article Interleukin-23 mediates the intestinal response to microbial beta-glucan and the development of spondyloarthritis pathology in SKG miceBenham, Helen, Rehaume, Linda M., Hasnain, Sumaira Z., Velasco, Jared, Baillet, Athan C., Ruutu, Merja, Kikly, Kristine, Wang, Ran, Tseng, Hsu-Wen, Thomas, Gethin P., Brown, Matthew A., Strutton, Geoffrey, McGuckin, Michael A. and Thomas, Ranjeny (2014). Interleukin-23 mediates the intestinal response to microbial beta-glucan and the development of spondyloarthritis pathology in SKG mice. Arthritis and Rheumatology, 66 (7), 1755-1767. doi: 10.1002/art.38638 |
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2013 Journal Article A molecular basis for the association of the HLA-DRB1 locus, citrullination, and rheumatoid arthritisScally, Stephen W., Petersen, Jan, Law, Soi Cheng, Dudek, Nadine L., Nel, Hendrik J., Loh, Khai Lee, Wijeyewickrema, Lakshmi C., Eckle, Sidonia B.G., van Heemst, Jurgen, Pike, Robert N., McCluskey, James, Toes, Rene E., La Gruta, Nicole L., Purcell, Anthony W., Reid, Hugh H., Thomas, Ranjeny and Rossjohn, Jamie (2013). A molecular basis for the association of the HLA-DRB1 locus, citrullination, and rheumatoid arthritis. Journal of Experimental Medicine, 210 (12), 2569-2582. doi: 10.1084/jem.20131241 |
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2012 Journal Article β-glucan triggers spondylarthritis and Crohn's disease–like ileitis in SKG miceRuutu, Merja, Thomas, Gethin, Steck, Roland, Degli-Esposti, Mariapia A., Zinkernagel, Martin S., Alexander, Kylie, Velasco, Jared, Strutton, Geoffrey, Tran, Ai, Benham, Helen, Rehaume, Linda, Wilson, Robert J., Kikly, Kristine, Davies, Julian, Pettit, Allison R., Brown, Matthew A., McGuckin, Michael A. and Thomas, Ranjeny (2012). β-glucan triggers spondylarthritis and Crohn's disease–like ileitis in SKG mice. Arthritis and Rheumatism, 64 (7), 2211-2222. doi: 10.1002/art.34423 |
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2009 Journal Article Antigen-specific suppression of inflammatory arthritis using liposomesCapini, Christelle, Jaturanpinyo, Montree, Chang, Hsin-I, Mutalik, Srinivas, McNally, Alice, Street, Shayna, Steptoe, Raymond, O'Sullivan, Brendan, Davies, Nigel and Thomas, Ranjeny (2009). Antigen-specific suppression of inflammatory arthritis using liposomes. Journal of Immunology, 182 (6), 3556-3565. doi: 10.4049/jimmunol.0802972 |
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2025 Journal Article AI automated radiographic scoring in rheumatoid arthritis: Shedding light on barriers to implementation through comprehensive evaluationBird, Alix, Oakden-Rayner, Lauren, Chakradeo, Katrina, Thomas, Ranjeny, Gupta, Drishti, Jain, Suyash, Jacob, Rohan, Ray, Shonket, Wechalekar, Mihir D, Proudman, Susanna and Palmer, Lyle J. (2025). AI automated radiographic scoring in rheumatoid arthritis: Shedding light on barriers to implementation through comprehensive evaluation. Seminars in Arthritis and Rheumatism, 74 152761, 152761-74. doi: 10.1016/j.semarthrit.2025.152761 |
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2025 Journal Article Interleukin-6 in synovial fluid drives the conversion of DC2s to DC3s in inflammatory arthritisDecker, Annika H., van den Hoogen, Lucas L., van Oorschot, Tom, Sanchez-Rocha, Liliana, Boks, Martine A., Bakdash, Ghaith, Thomas, Ranjeny, Popa, Calin D., Verdoes, Martijn, Thurlings, Rogier M., Becker, Anouk M.D. and de Vries, I. Jolanda M. (2025). Interleukin-6 in synovial fluid drives the conversion of DC2s to DC3s in inflammatory arthritis. iScience, 28 (7) 112957, 112957. doi: 10.1016/j.isci.2025.112957 |
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2025 Journal Article PD‐1 expressing islet‐specific CD4<sup>+</sup> T cells promote bystander tolerance and prevent autoimmunityLoaiza Naranjo, Jeniffer D., Zhang, Vivian, Ravichandran, Rathna, Bergot, Anne‐Sophie, Thomas, Ranjeny and Hamilton‐Williams, Emma E. (2025). PD‐1 expressing islet‐specific CD4+ T cells promote bystander tolerance and prevent autoimmunity. Immunology and Cell Biology imcb.70044. doi: 10.1111/imcb.70044 |
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2025 Journal Article Th Cell Phenotypes and Their Correlations with Disease Activity in Patients with Rheumatoid ArthritisXue, Meilang, Lin, Haiyan, Lynch, Tom, Chand, Vibhasha, Sinnathurai, Premarani, Thomas, Ranjeny, Keen, Helen, Hill, Catherine, Lester, Susan, Wechalekar, Mihir, Lassere, Marissa and March, Lyn (2025). Th Cell Phenotypes and Their Correlations with Disease Activity in Patients with Rheumatoid Arthritis. Journal of Clinical Medicine, 14 (12) 4220, 4220-12. doi: 10.3390/jcm14124220 |
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2025 Journal Article OP0150 DRUG-FREE REMISSION IS CHARACTERISED BY EXPANSION OF CITRULLINATED VIMENTIN-REACTIVE IMMUNE-REGULATORY CD4+CD39+TIGIThi T CELLS IN ACPA+ RHEUMATOID ARTHRITISAnderson, A.E., Lemos, H., Nel, H., Sorbet Santiago, S., Hee, J.Y., Rayner, F., Degnan, A., Wilson, I., Diboll, J., Sim, J., Melville, A., Siebert, S., McInnes, I.B., Goodyear, C.S., Hilkens, C., Filer, A., Raza, K., Buckley, C.D., Reid, H., Baker, K.F., Pratt, A., Rossjohn, J., Thomas, R. and Isaacs, J.D. (2025). OP0150 DRUG-FREE REMISSION IS CHARACTERISED BY EXPANSION OF CITRULLINATED VIMENTIN-REACTIVE IMMUNE-REGULATORY CD4+CD39+TIGIThi T CELLS IN ACPA+ RHEUMATOID ARTHRITIS. Annals of the Rheumatic Diseases, 84, 128-129. doi: 10.1016/j.ard.2025.05.171 |
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2025 Journal Article JAK inhibition and axial spondyloarthritis: new steps on the path to understanding pathophysiologyCiccia, Francesco, Mcgonagle, Dennis, Thomas, Ranjeny, Marzo-Ortega, Helena, Martin, David A., Yndestad, Arne and Volkov, Mikhail (2025). JAK inhibition and axial spondyloarthritis: new steps on the path to understanding pathophysiology. Frontiers in Immunology, 16 1488357, 1488357. doi: 10.3389/fimmu.2025.1488357 |
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2025 Journal Article Comparative study of management strategies for immune checkpoint inhibitor-induced inflammatory arthritis: rheumatologists versus oncologistsYoon, Jang S., Zhao, Frances, Masood, Hafsa, De Silva, Ravini, Binns, Jessie, Atkinson, Victoria, Thomas, Ranjeny and Terrill, Matthew (2025). Comparative study of management strategies for immune checkpoint inhibitor-induced inflammatory arthritis: rheumatologists versus oncologists. Internal Medicine Journal, 55 (3), 426-434. doi: 10.1111/imj.16629 |
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2025 Journal Article Therapeutic interception in individuals at risk of rheumatoid arthritis to prevent clinically impactful diseaseDeane, Kevin D, Holers, V Michael, Emery, Paul, Mankia, Kulveer, El Gabalawy, Hani, Sparks, Jeffrey A, Costenbader, Karen H, Schett, Georg, van der Helm-van Mil, Annette, van Schaardenburg, Dirkjan, Thomas, Ranjeny and Cope, Andrew P (2025). Therapeutic interception in individuals at risk of rheumatoid arthritis to prevent clinically impactful disease. Annals of the Rheumatic Diseases, 84 (1) 224211, 14-28. doi: 10.1136/ard-2023-224211 |
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2024 Conference Publication Unveiling the uterine-joint axis: dysbiosis and subclinical uterine inflammation in female axial spondyloarthritis pathogenesisMauro, Daniele, Vecellio, Matteo, Bergot, Anne-Sophie, Schmid, Eva, Forte, Giulio, Stingo, Alessia, Salzillo, Alessia, Pastore, Aldo, Aretini, Paolo, Di Lorenzo, Francesca, Ciancio, Antonio, Pantano, Ilenia, Saccone, Gabriele, Zullo, Fulvio, Montecucco, Carlo Maurizio, Rizzo, Aroldo, Schett, Georg, Thomas, Ranjeny, Zaiss, Mario and Ciccia, Francesco (2024). Unveiling the uterine-joint axis: dysbiosis and subclinical uterine inflammation in female axial spondyloarthritis pathogenesis. ACR Convergence: where rheumatology meets, Washington, DC, United States, 14 - 19 November 2024. Hoboken, NJ, United States: John Wiley & Sons. |
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2024 Conference Publication Self or Bacteria-reactive Th17 Expand from Conventional and Regulatory T Cells in Parabacteroides Goldsteinii Gnotobiotic Arthritic SKG Mice, in Context of Interferon-driven Synovial Inflammatory Macrophages and Reduced Bacterial Immune RegulationCai, Benjamin, Tuong, Zewen Kelvin, Morrison, Mark, Bergot, Anne-Sophie and Thomas, Ranjeny (2024). Self or Bacteria-reactive Th17 Expand from Conventional and Regulatory T Cells in Parabacteroides Goldsteinii Gnotobiotic Arthritic SKG Mice, in Context of Interferon-driven Synovial Inflammatory Macrophages and Reduced Bacterial Immune Regulation. ACR Convergence 2024, Washington, DC United States, 15–19 November 2024. Hoboken, NJ United States: John Wiley & Sons. |
