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2021

Conference Publication

Antigen-specific and bystander autoreactive T cell control in peripheral blood of ACPA plus rheumatoid arthritis patients administered antigen-specific tolerising immunotherapy

Wehr, Pascale, Thomas, Ranjeny, Ramnoruth, Nishta, Patel, Swati, Rossjohn, Jamie and Reid, Hugh (2021). Antigen-specific and bystander autoreactive T cell control in peripheral blood of ACPA plus rheumatoid arthritis patients administered antigen-specific tolerising immunotherapy. ACR Convergence Conference, Virtual, 5-9 November 2021. Hoboken, NJ, United States: John Wiley & Sons. doi: 10.1002/art.41966

Antigen-specific and bystander autoreactive T cell control in peripheral blood of ACPA plus rheumatoid arthritis patients administered antigen-specific tolerising immunotherapy

2021

Conference Publication

A Combined Patient Registry and Biobank Laboratory Information System for Prospective Multisite Chronic Rheumatic Disease Research Using REDCap

Willers, Craig, Lynch, Tom, Chand, Vibhasha, Islam, Mohammad, Lassere, Marissa, Keen, Helen, Kenna, Tony, Lester, Susan, Thomas, Ranjeny, Sinnathurai, Premarani, Wechalekar, Mihir, Fletcher, Ashley, Lightowler, Daniel, Mohd, Sheeraz, Ramnoruth, Nishta, Ruediger, Carlee, Weedon, Helen and March, Lyn (2021). A Combined Patient Registry and Biobank Laboratory Information System for Prospective Multisite Chronic Rheumatic Disease Research Using REDCap. ACR Convergence Conference, Electr Network, Nov 05-09, 2021. HOBOKEN: WILEY.

A Combined Patient Registry and Biobank Laboratory Information System for Prospective Multisite Chronic Rheumatic Disease Research Using REDCap

2021

Journal Article

Associations of baseline use of biologic or targeted synthetic DMARDs with COVID-19 severity in rheumatoid arthritis: Results from the COVID-19 Global Rheumatology Alliance physician registry

Sparks, Jeffrey A, Wallace, Zachary S, Seet, Andrea M, Gianfrancesco, Milena A, Izadi, Zara, Hyrich, Kimme L, Strangfeld, Anja, Gossec, Laure, Carmona, Loreto, Mateus, Elsa F, Lawson-Tovey, Saskia, Trupin, Laura, Rush, Stephanie, Katz, Patricia, Schmajuk, Gabriela, Jacobsohn, Lindsay, Wise, Leanna, Gilbert, Emily L, Duarte-Garciá, Ali, Valenzuela-Almada, Maria O, Pons-Estel, Guillermo J, Isnardi, Carolina A, Berbotto, Guillermo A, Hsu, Tiffany Y-T, D'Silva, Kristin M, Patel, Naomi J, Kearsley-Fleet, Lianne, Schäfer, Martin, Ribeiro, Sandra Lúcia Euzébio ... Yazdany, Jinoos (2021). Associations of baseline use of biologic or targeted synthetic DMARDs with COVID-19 severity in rheumatoid arthritis: Results from the COVID-19 Global Rheumatology Alliance physician registry. Annals of the Rheumatic Diseases, 80 (9), 1137-1146. doi: 10.1136/annrheumdis-2021-220418

Associations of baseline use of biologic or targeted synthetic DMARDs with COVID-19 severity in rheumatoid arthritis: Results from the COVID-19 Global Rheumatology Alliance physician registry

2021

Journal Article

Preclinical models of arthritis for studying immunotherapy and immune tolerance

Meehan, Gavin R., Thomas, Ranjeny, Al Khabouri, Shaima, Wehr, Pascale, Hilkens, Catharien M.U., Wraith, David C., Sieghart, Daniela, Bonelli, Michael, Nagy, György, Garside, Paul, Tough, David F., Lewis, Huw D. and Brewer, James M. (2021). Preclinical models of arthritis for studying immunotherapy and immune tolerance. Annals of the Rheumatic Diseases, 80 (10), 1268-1277. doi: 10.1136/annrheumdis-2021-220043

Preclinical models of arthritis for studying immunotherapy and immune tolerance

2021

Journal Article

Overcoming obstacles in the development of antigen-specific immunotherapies for Type 1 diabetes

Thomas, Ranjeny, Carballido, José M., Wesley, Johnna D. and Ahmed, Simi T. (2021). Overcoming obstacles in the development of antigen-specific immunotherapies for Type 1 diabetes. Frontiers in Immunology, 12 730414, 730414. doi: 10.3389/fimmu.2021.730414

Overcoming obstacles in the development of antigen-specific immunotherapies for Type 1 diabetes

2021

Journal Article

Potential for antigen-specific tolerizing immunotherapy in systematic lupus erythematosus

Robinson, Sean and Thomas, Ranjeny (2021). Potential for antigen-specific tolerizing immunotherapy in systematic lupus erythematosus. Frontiers in Immunology, 12 654701, 654701. doi: 10.3389/fimmu.2021.654701

Potential for antigen-specific tolerizing immunotherapy in systematic lupus erythematosus

2021

Journal Article

Mediation of interleukin-23 and tumor necrosis factor–driven reactive arthritis by Chlamydia-infected macrophages in SKG mice

Romand, Xavier, Liu, Xiao, Rahman, M. Arifur, Bhuyan, Zaied Ahmed, Douillard, Claire, Arora Kedia, Reena, Stone, Nathan, Roest, Dominique, Chew, Zi Huai, Cameron, Amy J., Rehaume, Linda M., Bozon, Aurélie, Habib, Mohammed, Armitage, Charles W., Nguyen, Minh Vu Chuong, Favier, Bertrand, Beagley, Kenneth, Maurin, Max, Gaudin, Philippe, Thomas, Ranjeny, Wells, Timothy J. and Baillet, Athan (2021). Mediation of interleukin-23 and tumor necrosis factor–driven reactive arthritis by Chlamydia-infected macrophages in SKG mice. Arthritis and Rheumatology, 73 (7) art.41653, 1200-1210. doi: 10.1002/art.41653

Mediation of interleukin-23 and tumor necrosis factor–driven reactive arthritis by Chlamydia-infected macrophages in SKG mice

2021

Journal Article

Ankylosing spondylitis: an autoimmune or autoinflammatory disease?

Mauro, Daniele, Thomas, Ranjeny, Guggino, Giuliana, Lories, Rik, Brown, Matthew A. and Ciccia, Francesco (2021). Ankylosing spondylitis: an autoimmune or autoinflammatory disease?. Nature Reviews Rheumatology, 17 (7), 387-404. doi: 10.1038/s41584-021-00625-y

Ankylosing spondylitis: an autoimmune or autoinflammatory disease?

2021

Conference Publication

Associations Of Baseline Use Of Biologic Or Targeted Synthetic DMARDs With COVID-19 Severity In Rheumatoid Arthritis: Results From The COVID-19 Global Rheumatology Alliance

Sparks, J., Wallace, Z., Seet, A., Gianfrancesco, M., Izadi, Z., Hyrich, K., Strangfeld, A., Gossec, L., Carmona, L., Mateus, E., Lawson-Tovey, S., Trupin, L., Rush, S., Schmajuk, G., Katz, P., Jacobsohn, L., Al Emadi, S., Wise, L., Gilbert, E., Duarte-Garcia, A., Valenzuela-Almada, M., Hsu, T., D'silva, K., Serling-Boyd, N., Dieudé, P., Nikiphorou, E., Kronzer, V., Singh, N., Ugarte-Gil, M.F. ... Alliance, on behalf of COVID-19 Global Rheumatology (2021). Associations Of Baseline Use Of Biologic Or Targeted Synthetic DMARDs With COVID-19 Severity In Rheumatoid Arthritis: Results From The COVID-19 Global Rheumatology Alliance. EULAR 2021 European Congress of Rheumatology, Online, 2-5 June 2021. London, United Kingdom: BMJ. doi: 10.1136/annrheumdis-2021-eular.1632

Associations Of Baseline Use Of Biologic Or Targeted Synthetic DMARDs With COVID-19 Severity In Rheumatoid Arthritis: Results From The COVID-19 Global Rheumatology Alliance

2021

Journal Article

Inflammasome activation in ankylosing spondylitis is associated to gut dysbiosis

Guggino, Giuliana, Mauro, Daniele, Rizzo, Aroldo, Alessandro, Riccardo, Raimondo, Stefania, Bergot, Anne-Sophie, Rahman, M Arifur, Ellis, Jonathan J., Milling, Simon, Lories, Rik, Elewaut, Dirk, Brown, Matthew A., Thomas, Ranjeny and Ciccia, Francesco (2021). Inflammasome activation in ankylosing spondylitis is associated to gut dysbiosis. Arthritis and Rheumatology, 73 (7) art.41644, 1189-1199. doi: 10.1002/art.41644

Inflammasome activation in ankylosing spondylitis is associated to gut dysbiosis

2021

Conference Publication

Monitoring antigen-specific functional CD4 t cells using a peptide-MHC Class-II tetramer staining based qualified assay in rheumatoid arthritis patients

Patel, Swati, Ramnoruth, Nishta, Wehr, Pascale, Rossjohn, Jamie, Reid, Hugh, Campbell, Kim, Nel, Hendrik and Thomas, Ranjeny Thomas (2021). Monitoring antigen-specific functional CD4 t cells using a peptide-MHC Class-II tetramer staining based qualified assay in rheumatoid arthritis patients. Australian Rheumatology Association 61st Annual Scientific Meeting, Hybrid Meeting, 21–23 May 2021. Richmond, VIC, Australia: Wiley-Blackwell.

Monitoring antigen-specific functional CD4 t cells using a peptide-MHC Class-II tetramer staining based qualified assay in rheumatoid arthritis patients

2021

Conference Publication

Antigen-expanded t cells infiltrating new-onset rheumatoid arthritis synovial tissue are IL-6-reponsive, T-helper 2 and pro-inflammatory viral-specific clones

Wehr, Pascale, Nel, Hendrik J., Zhou, Chenhao, Mehdi, Ahmed M., McGuire, Helen, Weedon, Helen, Small, Annabelle, Steptoe, Raymond, Gras, Stephanie, Wechalekar, Mihir D. and Thomas, Ranjeny (2021). Antigen-expanded t cells infiltrating new-onset rheumatoid arthritis synovial tissue are IL-6-reponsive, T-helper 2 and pro-inflammatory viral-specific clones. Australian Rheumatology Association 61st Annual Scientific Meeting, Hybrid Meeting, 21–23 May 2021. Richmond, VIC, Australia: Wiley-Blackwell.

Antigen-expanded t cells infiltrating new-onset rheumatoid arthritis synovial tissue are IL-6-reponsive, T-helper 2 and pro-inflammatory viral-specific clones

2021

Journal Article

A patient-centered knowledge translation tool for treat-to-target strategy in rheumatoid arthritis: patient and rheumatologist perspectives

Benham, Helen, Chiu, Hedva, Tesiram, Joanne, Mehdi, Ahmed, Landsberg, Peter, Grosman, Sergei, Harrison, Andrew, Nash, Peter, Thomas, Ranjeny, Langbecker, Danette and Van Driel, Mieke (2021). A patient-centered knowledge translation tool for treat-to-target strategy in rheumatoid arthritis: patient and rheumatologist perspectives. International Journal of Rheumatic Diseases, 24 (3), 355-363. doi: 10.1111/1756-185x.14051

A patient-centered knowledge translation tool for treat-to-target strategy in rheumatoid arthritis: patient and rheumatologist perspectives

2021

Journal Article

Streptococcus species enriched in the oral cavity of patients with RA are a source of peptidoglycan-polysaccharide polymers that can induce arthritis in mice

Moentadj, Rabia, Wang, Yiwen, Bowerman, Kate, Rehaume, Linda, Nel, Hendrik, O Cuiv, Paraic, Stephens, Juliette, Baharom, Amalina, Maradana, Muralidhara, Lakis, Vanessa, Morrison, Mark, Wells, Timothy, Hugenholtz, Philip, Benham, Helen, Le Cao, Kim-Anh and Thomas, Ranjeny (2021). Streptococcus species enriched in the oral cavity of patients with RA are a source of peptidoglycan-polysaccharide polymers that can induce arthritis in mice. Annals of the Rheumatic Diseases, 80 (5) annrheumdis-2020-219009, annrheumdis-2020. doi: 10.1136/annrheumdis-2020-219009

Streptococcus species enriched in the oral cavity of patients with RA are a source of peptidoglycan-polysaccharide polymers that can induce arthritis in mice

2021

Journal Article

CD4+CD25+CD127hi cell frequency predicts disease progression in type 1 diabetes

Narsale, Aditi, Lam, Breanna, Moya, Rosa, Lu, TingTing, Mandelli, Alessandra, Gotuzzo, Irene, Pessina, Benedetta, Giamporcaro, Gianmaria, Geoffrey, Rhonda, Buchanan, Kerry, Harris, Mark, Bergot, Anne-Sophie, Thomas, Ranjeny, Hessner, Martin J., Battaglia, Manuela, Serti, Elisavet and Davies, Joanna D. (2021). CD4+CD25+CD127hi cell frequency predicts disease progression in type 1 diabetes. JCI Insight, 6 (2) e136114. doi: 10.1172/jci.insight.136114

CD4+CD25+CD127hi cell frequency predicts disease progression in type 1 diabetes

2021

Journal Article

Rheumatoid arthritis is a preventable disease: 11 ways to reduce your patients’ risk

Koller‐Smith, Louise, Mehdi, Ahmed M., March, Lyn, Tooth, Leigh, Mishra, Gita and Thomas, Ranjeny (2021). Rheumatoid arthritis is a preventable disease: 11 ways to reduce your patients’ risk. Internal Medicine Journal, 52 (5), 711-716. doi: 10.1111/imj.15537

Rheumatoid arthritis is a preventable disease: 11 ways to reduce your patients’ risk

2021

Journal Article

Proinsulin‐specific T‐cell responses correlate with estimated c‐peptide and predict partial remission duration in type 1 diabetes

Musthaffa, Yassmin, Hamilton‐Williams, Emma E, Nel, Hendrik J., Bergot, Anne‐Sophie, Mehdi, Ahmed M., Harris, Mark and Thomas, Ranjeny (2021). Proinsulin‐specific T‐cell responses correlate with estimated c‐peptide and predict partial remission duration in type 1 diabetes. Clinical & Translational Immunology, 10 (7) e1315, e1315. doi: 10.1002/cti2.1315

Proinsulin‐specific T‐cell responses correlate with estimated c‐peptide and predict partial remission duration in type 1 diabetes

2020

Journal Article

Optimization of a method to detect autoantigen-specific t-cell responses in type 1 diabetes

Musthaffa, Yassmin, Nel, Hendrik J., Ramnoruth, Nishta, Patel, Swati, Hamilton-Williams, Emma E., Harris, Mark and Thomas, Ranjeny (2020). Optimization of a method to detect autoantigen-specific t-cell responses in type 1 diabetes. Frontiers in Immunology, 11 587469, 587469. doi: 10.3389/fimmu.2020.587469

Optimization of a method to detect autoantigen-specific t-cell responses in type 1 diabetes

2020

Journal Article

Autoantigens in rheumatoid arthritis and the potential for antigen-specific tolerising immunotherapy

Nel, Hendrik J., Malmström, Vivianne, Wraith, David C. and Thomas, Ranjeny (2020). Autoantigens in rheumatoid arthritis and the potential for antigen-specific tolerising immunotherapy. The Lancet Rheumatology, 2 (11), e712-e723. doi: 10.1016/S2665-9913(20)30344-1

Autoantigens in rheumatoid arthritis and the potential for antigen-specific tolerising immunotherapy

2020

Conference Publication

Mapping Oligoclonally Expanded T Cells Within the Peripheral and Synovial Immune Landscape of Untreated ACPA plus Rheumatoid Arthritis Patients at the Single Cell Level

Wehr, Pascale, Nel, Hendrik, Zhou, Chenhao, Mehdi, Ahmed, Christ, Angelika, Weedon, Helen, Wechalekar, Mihir and Thomas, Ranjeny (2020). Mapping Oligoclonally Expanded T Cells Within the Peripheral and Synovial Immune Landscape of Untreated ACPA plus Rheumatoid Arthritis Patients at the Single Cell Level. ACR Convergence 2020, Virtual, 5-9 November 2020. Hoboken, NJ, United States: John Wiley & Sons. doi: 10.1002/art.41538

Mapping Oligoclonally Expanded T Cells Within the Peripheral and Synovial Immune Landscape of Untreated ACPA plus Rheumatoid Arthritis Patients at the Single Cell Level