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2022 Journal Article Evaluation of a fit-for-purpose assay to monitor antigen-specific functional CD4+ T-cell subpopulations in rheumatoid arthritis using flow cytometry-based peptide-MHC class-II tetramer stainingPatel, Swati, Ramnoruth, Nishta, Wehr, Pascale, Rossjohn, Jamie, Reid, Hugh H., Campbell, Kim, Nel, Hendrik J. and Thomas, Ranjeny (2022). Evaluation of a fit-for-purpose assay to monitor antigen-specific functional CD4+ T-cell subpopulations in rheumatoid arthritis using flow cytometry-based peptide-MHC class-II tetramer staining. Clinical and Experimental Immunology, 207 (1), 72-83. doi: 10.1093/cei/uxab008 |
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2022 Other Outputs E.PAGE: A curated database and enrichment tool to predict gene modules associated with gene-environment interactionsMuralidharan, Sachin, Ali, Sarah, Yang, Lilin, Badshah, Joshua, Zahir, Farah, Ali, Rubbiya, Chandra, Janin, Thomas, Ranjeny and Mehdi, Ahmed M. (2022). E.PAGE: A curated database and enrichment tool to predict gene modules associated with gene-environment interactions. doi: 10.1101/2022.01.03.474848 |
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2022 Journal Article Tolerance induction by liposomes targeting a single CD8 epitope IGRP in a model of type 1 diabetes is impeded by co-targeting a CD4 islet epitopeBuckle, Irina, Loaiza Naranjo, Jeniffer D., Bergot, Anne-Sophie, Zhang, Vivian, Talekar, Meghna, Steptoe, Raymond J., Thomas, Ranjeny and Hamilton-Williams, Emma E. (2022). Tolerance induction by liposomes targeting a single CD8 epitope IGRP in a model of type 1 diabetes is impeded by co-targeting a CD4 islet epitope. Immunology and Cell Biology, 100 (1), 33-48. doi: 10.1111/imcb.12506 |
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2021 Journal Article IL-6 receptor blockade does not slow β cell loss in new-onset type 1 diabetesGreenbaum, Carla J., Serti, Elisavet, Lambert, Katharina, Weiner, Lia J., Kanaparthi, Sai, Lord, Sandra, Gitelman, Stephen E., Wilson, Darrell M., Gaglia, Jason L., Griffin, Kurt J., Russell, William E., Raskin, Philip, Moran, Antoinette, Willi, Steven M., Tsalikian, Eva, DiMeglio, Linda A., Herold, Kevan C., Moore, Wayne V., Goland, Robin, Harris, Mark, Craig, Maria E., Schatz, Desmond A., Baidal, David A., Rodriguez, Henry, Utzschneider, Kristina M., Nel, Hendrik J., Soppe, Carol L., Boyle, Karen D., Cerosaletti, Karen ... Sanda, Srinath (2021). IL-6 receptor blockade does not slow β cell loss in new-onset type 1 diabetes. JCI Insight, 6 (21) e150074. doi: 10.1172/jci.insight.150074 |
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2021 Conference Publication Antigen-specific and bystander autoreactive T cell control in peripheral blood of ACPA plus rheumatoid arthritis patients administered antigen-specific tolerising immunotherapyWehr, Pascale, Thomas, Ranjeny, Ramnoruth, Nishta, Patel, Swati, Rossjohn, Jamie and Reid, Hugh (2021). Antigen-specific and bystander autoreactive T cell control in peripheral blood of ACPA plus rheumatoid arthritis patients administered antigen-specific tolerising immunotherapy. ACR Convergence Conference, Virtual, 5-9 November 2021. Hoboken, NJ, United States: John Wiley & Sons. doi: 10.1002/art.41966 |
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2021 Conference Publication A Combined Patient Registry and Biobank Laboratory Information System for Prospective Multisite Chronic Rheumatic Disease Research Using REDCapWillers, Craig, Lynch, Tom, Chand, Vibhasha, Islam, Mohammad, Lassere, Marissa, Keen, Helen, Kenna, Tony, Lester, Susan, Thomas, Ranjeny, Sinnathurai, Premarani, Wechalekar, Mihir, Fletcher, Ashley, Lightowler, Daniel, Mohd, Sheeraz, Ramnoruth, Nishta, Ruediger, Carlee, Weedon, Helen and March, Lyn (2021). A Combined Patient Registry and Biobank Laboratory Information System for Prospective Multisite Chronic Rheumatic Disease Research Using REDCap. ACR Convergence Conference, Electr Network, Nov 05-09, 2021. HOBOKEN: WILEY. |
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2021 Journal Article Associations of baseline use of biologic or targeted synthetic DMARDs with COVID-19 severity in rheumatoid arthritis: Results from the COVID-19 Global Rheumatology Alliance physician registrySparks, Jeffrey A, Wallace, Zachary S, Seet, Andrea M, Gianfrancesco, Milena A, Izadi, Zara, Hyrich, Kimme L, Strangfeld, Anja, Gossec, Laure, Carmona, Loreto, Mateus, Elsa F, Lawson-Tovey, Saskia, Trupin, Laura, Rush, Stephanie, Katz, Patricia, Schmajuk, Gabriela, Jacobsohn, Lindsay, Wise, Leanna, Gilbert, Emily L, Duarte-Garciá, Ali, Valenzuela-Almada, Maria O, Pons-Estel, Guillermo J, Isnardi, Carolina A, Berbotto, Guillermo A, Hsu, Tiffany Y-T, D'Silva, Kristin M, Patel, Naomi J, Kearsley-Fleet, Lianne, Schäfer, Martin, Ribeiro, Sandra Lúcia Euzébio ... Yazdany, Jinoos (2021). Associations of baseline use of biologic or targeted synthetic DMARDs with COVID-19 severity in rheumatoid arthritis: Results from the COVID-19 Global Rheumatology Alliance physician registry. Annals of the Rheumatic Diseases, 80 (9), 1137-1146. doi: 10.1136/annrheumdis-2021-220418 |
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2021 Journal Article Preclinical models of arthritis for studying immunotherapy and immune toleranceMeehan, Gavin R., Thomas, Ranjeny, Al Khabouri, Shaima, Wehr, Pascale, Hilkens, Catharien M.U., Wraith, David C., Sieghart, Daniela, Bonelli, Michael, Nagy, György, Garside, Paul, Tough, David F., Lewis, Huw D. and Brewer, James M. (2021). Preclinical models of arthritis for studying immunotherapy and immune tolerance. Annals of the Rheumatic Diseases, 80 (10), 1268-1277. doi: 10.1136/annrheumdis-2021-220043 |
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2021 Journal Article Overcoming obstacles in the development of antigen-specific immunotherapies for Type 1 diabetesThomas, Ranjeny, Carballido, José M., Wesley, Johnna D. and Ahmed, Simi T. (2021). Overcoming obstacles in the development of antigen-specific immunotherapies for Type 1 diabetes. Frontiers in Immunology, 12 730414, 730414. doi: 10.3389/fimmu.2021.730414 |
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2021 Journal Article Potential for antigen-specific tolerizing immunotherapy in systematic lupus erythematosusRobinson, Sean and Thomas, Ranjeny (2021). Potential for antigen-specific tolerizing immunotherapy in systematic lupus erythematosus. Frontiers in Immunology, 12 654701, 654701. doi: 10.3389/fimmu.2021.654701 |
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2021 Journal Article Mediation of interleukin-23 and tumor necrosis factor–driven reactive arthritis by Chlamydia-infected macrophages in SKG miceRomand, Xavier, Liu, Xiao, Rahman, M. Arifur, Bhuyan, Zaied Ahmed, Douillard, Claire, Arora Kedia, Reena, Stone, Nathan, Roest, Dominique, Chew, Zi Huai, Cameron, Amy J., Rehaume, Linda M., Bozon, Aurélie, Habib, Mohammed, Armitage, Charles W., Nguyen, Minh Vu Chuong, Favier, Bertrand, Beagley, Kenneth, Maurin, Max, Gaudin, Philippe, Thomas, Ranjeny, Wells, Timothy J. and Baillet, Athan (2021). Mediation of interleukin-23 and tumor necrosis factor–driven reactive arthritis by Chlamydia-infected macrophages in SKG mice. Arthritis and Rheumatology, 73 (7) art.41653, 1200-1210. doi: 10.1002/art.41653 |
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2021 Journal Article Ankylosing spondylitis: an autoimmune or autoinflammatory disease?Mauro, Daniele, Thomas, Ranjeny, Guggino, Giuliana, Lories, Rik, Brown, Matthew A. and Ciccia, Francesco (2021). Ankylosing spondylitis: an autoimmune or autoinflammatory disease?. Nature Reviews Rheumatology, 17 (7), 387-404. doi: 10.1038/s41584-021-00625-y |
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2021 Conference Publication Associations Of Baseline Use Of Biologic Or Targeted Synthetic DMARDs With COVID-19 Severity In Rheumatoid Arthritis: Results From The COVID-19 Global Rheumatology AllianceSparks, J., Wallace, Z., Seet, A., Gianfrancesco, M., Izadi, Z., Hyrich, K., Strangfeld, A., Gossec, L., Carmona, L., Mateus, E., Lawson-Tovey, S., Trupin, L., Rush, S., Schmajuk, G., Katz, P., Jacobsohn, L., Al Emadi, S., Wise, L., Gilbert, E., Duarte-Garcia, A., Valenzuela-Almada, M., Hsu, T., D'silva, K., Serling-Boyd, N., Dieudé, P., Nikiphorou, E., Kronzer, V., Singh, N., Ugarte-Gil, M.F. ... Alliance, on behalf of COVID-19 Global Rheumatology (2021). Associations Of Baseline Use Of Biologic Or Targeted Synthetic DMARDs With COVID-19 Severity In Rheumatoid Arthritis: Results From The COVID-19 Global Rheumatology Alliance. EULAR 2021 European Congress of Rheumatology, Online, 2-5 June 2021. London, United Kingdom: BMJ. doi: 10.1136/annrheumdis-2021-eular.1632 |
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2021 Journal Article Inflammasome activation in ankylosing spondylitis is associated to gut dysbiosisGuggino, Giuliana, Mauro, Daniele, Rizzo, Aroldo, Alessandro, Riccardo, Raimondo, Stefania, Bergot, Anne-Sophie, Rahman, M Arifur, Ellis, Jonathan J., Milling, Simon, Lories, Rik, Elewaut, Dirk, Brown, Matthew A., Thomas, Ranjeny and Ciccia, Francesco (2021). Inflammasome activation in ankylosing spondylitis is associated to gut dysbiosis. Arthritis and Rheumatology, 73 (7) art.41644, 1189-1199. doi: 10.1002/art.41644 |
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2021 Conference Publication Monitoring antigen-specific functional CD4 t cells using a peptide-MHC Class-II tetramer staining based qualified assay in rheumatoid arthritis patientsPatel, Swati, Ramnoruth, Nishta, Wehr, Pascale, Rossjohn, Jamie, Reid, Hugh, Campbell, Kim, Nel, Hendrik and Thomas, Ranjeny Thomas (2021). Monitoring antigen-specific functional CD4 t cells using a peptide-MHC Class-II tetramer staining based qualified assay in rheumatoid arthritis patients. Australian Rheumatology Association 61st Annual Scientific Meeting, Hybrid Meeting, 21–23 May 2021. Richmond, VIC, Australia: Wiley-Blackwell. |
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2021 Conference Publication Antigen-expanded t cells infiltrating new-onset rheumatoid arthritis synovial tissue are IL-6-reponsive, T-helper 2 and pro-inflammatory viral-specific clonesWehr, Pascale, Nel, Hendrik J., Zhou, Chenhao, Mehdi, Ahmed M., McGuire, Helen, Weedon, Helen, Small, Annabelle, Steptoe, Raymond, Gras, Stephanie, Wechalekar, Mihir D. and Thomas, Ranjeny (2021). Antigen-expanded t cells infiltrating new-onset rheumatoid arthritis synovial tissue are IL-6-reponsive, T-helper 2 and pro-inflammatory viral-specific clones. Australian Rheumatology Association 61st Annual Scientific Meeting, Hybrid Meeting, 21–23 May 2021. Richmond, VIC, Australia: Wiley-Blackwell. |
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2021 Journal Article A patient-centered knowledge translation tool for treat-to-target strategy in rheumatoid arthritis: patient and rheumatologist perspectivesBenham, Helen, Chiu, Hedva, Tesiram, Joanne, Mehdi, Ahmed, Landsberg, Peter, Grosman, Sergei, Harrison, Andrew, Nash, Peter, Thomas, Ranjeny, Langbecker, Danette and Van Driel, Mieke (2021). A patient-centered knowledge translation tool for treat-to-target strategy in rheumatoid arthritis: patient and rheumatologist perspectives. International Journal of Rheumatic Diseases, 24 (3), 355-363. doi: 10.1111/1756-185x.14051 |
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2021 Journal Article Streptococcus species enriched in the oral cavity of patients with RA are a source of peptidoglycan-polysaccharide polymers that can induce arthritis in miceMoentadj, Rabia, Wang, Yiwen, Bowerman, Kate, Rehaume, Linda, Nel, Hendrik, O Cuiv, Paraic, Stephens, Juliette, Baharom, Amalina, Maradana, Muralidhara, Lakis, Vanessa, Morrison, Mark, Wells, Timothy, Hugenholtz, Philip, Benham, Helen, Le Cao, Kim-Anh and Thomas, Ranjeny (2021). Streptococcus species enriched in the oral cavity of patients with RA are a source of peptidoglycan-polysaccharide polymers that can induce arthritis in mice. Annals of the Rheumatic Diseases, 80 (5) annrheumdis-2020-219009, annrheumdis-2020. doi: 10.1136/annrheumdis-2020-219009 |
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2021 Journal Article CD4+CD25+CD127hi cell frequency predicts disease progression in type 1 diabetesNarsale, Aditi, Lam, Breanna, Moya, Rosa, Lu, TingTing, Mandelli, Alessandra, Gotuzzo, Irene, Pessina, Benedetta, Giamporcaro, Gianmaria, Geoffrey, Rhonda, Buchanan, Kerry, Harris, Mark, Bergot, Anne-Sophie, Thomas, Ranjeny, Hessner, Martin J., Battaglia, Manuela, Serti, Elisavet and Davies, Joanna D. (2021). CD4+CD25+CD127hi cell frequency predicts disease progression in type 1 diabetes. JCI Insight, 6 (2) e136114. doi: 10.1172/jci.insight.136114 |
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2021 Journal Article Proinsulin‐specific T‐cell responses correlate with estimated c‐peptide and predict partial remission duration in type 1 diabetesMusthaffa, Yassmin, Hamilton‐Williams, Emma E, Nel, Hendrik J., Bergot, Anne‐Sophie, Mehdi, Ahmed M., Harris, Mark and Thomas, Ranjeny (2021). Proinsulin‐specific T‐cell responses correlate with estimated c‐peptide and predict partial remission duration in type 1 diabetes. Clinical & Translational Immunology, 10 (7) e1315, e1315. doi: 10.1002/cti2.1315 |
