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2017 Conference Publication Impaired Control of Autoreactive T Cell Expansion Is Coupled with Type-1 Regulatory T Cell Deficiency in BALB/c ZAP70W163C Mutant MiceRahman, M. Arifur, Montizaan, Daphne, Bhuyan, Zaied Ahmed, Rehaume, Linda and Thomas, Ranjeny (2017). Impaired Control of Autoreactive T Cell Expansion Is Coupled with Type-1 Regulatory T Cell Deficiency in BALB/c ZAP70W163C Mutant Mice. 2017 ACR/ARHP Pediatric Rheumatology Symposium, San Diego, California, 3-8 November 2017. Hoboken, NJ, United States: John Wiley & Sons. |
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2016 Journal Article Treatment with dexamethasone and monophosphoryl lipid a removes disease-associated transcriptional signatures in monocyte-derived dendritic cells from rheumatoid arthritis patients and confers tolerogenic featuresGarcia-Gonzalez, Paulina A., Schinnerling, Katina, Sepulveda-Gutierrez, Alejandro, Maggi, Jaxaira, Hoyos, Lorena, Morales, Rodrigo A., Mehdi, Ahmed M., Nel, Hendrik J., Soto, Lilian, Pesce, Barbara, Carmen Molina, Maria, Cuchacovich, Miguel, Larrondo, Milton L., Neira, Oscar, Francisco Catalan, Diego, Hilkens, Catharien M., Thomas, Ranjeny, Verdugo, Ricardo A. and Aguillon, Juan C. (2016). Treatment with dexamethasone and monophosphoryl lipid a removes disease-associated transcriptional signatures in monocyte-derived dendritic cells from rheumatoid arthritis patients and confers tolerogenic features. Frontiers in Immunology, 7 (OCT) 458, 458. doi: 10.3389/fimmu.2016.00458 |
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2016 Conference Publication Genetic Association of Ankylosing Spondylitis with TBX21 Influences T-Bet and Pro-Inflammatory Cytokine Expression in Humans and SKG Mice As a Model of Spondyloarthritis and Alters Host Microbiome and Response to Microbial StimuliLau, Max, Keith, Patricia, McCready, Madeline, Costello, Mary-Ellen, Bradbury, Linda, Hollis, Kelly, Thomas, Ranjeny, Thomas, Gethin P., Brown, Matthew A. and Kenna, Tony J. (2016). Genetic Association of Ankylosing Spondylitis with TBX21 Influences T-Bet and Pro-Inflammatory Cytokine Expression in Humans and SKG Mice As a Model of Spondyloarthritis and Alters Host Microbiome and Response to Microbial Stimuli. Annual Meeting of the American-College-of-Rheumatology/Association-of-Rheumatology-Health-Professionals (ACR/ARHP), Washington Dc, Nov 11-16, 2016. HOBOKEN: WILEY. |
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2016 Conference Publication Heightened MAIT Cell Sensitivity to MR1 Ligands Could Impact Control of Dysbiosis in Patients with Rheumatoid Arthritis and Ankylosing SpondylitisJansen, Diahann, Klinken, Elizabeth, Nel, Hendrik, Law, Soi Cheng, Benham, Helen, Cummins, Lisa, Brown, Matthew, Kenna, Tony, Liu, Ligong, Fairlie, David, Rossjohn, Jamie, Morrison, Mark, Thomas, Ranjeny, Cuiv, Paraic O., McCluskey, James and Corbett, Alexandra (2016). Heightened MAIT Cell Sensitivity to MR1 Ligands Could Impact Control of Dysbiosis in Patients with Rheumatoid Arthritis and Ankylosing Spondylitis. 2016 ACR/ARHP Annual Meeting, Washington, DC, United States, 11-16 November 2016. Hoboken, NJ, United States: John Wiley & Sons. doi: 10.1002/art.39977 |
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2016 Conference Publication Treatment with dexamethasone and monophosphoryl lipid a removes disease-associated transcriptional signatures in monocyte-derived dendritic cells from rheumatoid arthritis patients and confers the ability to modulate CD4+T cell responsesGarcia-Gonzalez, Paulina, Neira, Oscar, Schinnerling, Katina, Sepulveda-Gutierrez, Alejandro, Maggy, Jaxaira, Hoyos, Lorena, Morales, Rodrigo, Ubilla-Olguin, Gabriela, Mehdi, Ahmed, Nel, Hendrik, Soto, Lilian, Pesce, Barbara, Carmen Molina, Maria, Cuchacovich, Miguel, Larrondo, Milton, Catalan, Diego, Hilkens, Catharien M., Thomas, Ranjeny, Verdugo, Ricardo and Aguillon, Juan C. (2016). Treatment with dexamethasone and monophosphoryl lipid a removes disease-associated transcriptional signatures in monocyte-derived dendritic cells from rheumatoid arthritis patients and confers the ability to modulate CD4+T cell responses. Annual Meeting of the American-College-of-Rheumatology/Association-of-Rheumatology-Health-Professionals (ACR/ARHP), Washington, DC, United States, 11-16 November 2016. Hoboken, NJ, United States: John Wiley & Sons. |
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2016 Journal Article Reduced interleukin-2 responsiveness impairs the ability of Treg cells to compete for IL-2 in nonobese diabetic miceJames, Cini R., Buckle, Irina, Muscate, Franziska, Otsuka, Masayuki, Nakao, Mari, Oon, Jack S. H., Steptoe, Raymond J., Thomas, Ranjeny and Hamilton-Williams, Emma E. (2016). Reduced interleukin-2 responsiveness impairs the ability of Treg cells to compete for IL-2 in nonobese diabetic mice. Immunology and Cell Biology, 94 (5), 509-519. doi: 10.1038/icb.2016.7 |
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2016 Journal Article Development and performance evaluation of novel nanoparticles of a grafted copolymer loaded with curcuminMutalik, Srinivas, Suthar, Neelam A., Managuli, Renuka S., Shetty, Pallavi K., Avadhani, Kiran, Kalthur, Guruprasad, Kulkarni, Raghavendra V. and Thomas, Ranjeny (2016). Development and performance evaluation of novel nanoparticles of a grafted copolymer loaded with curcumin. International Journal of Biological Macromolecules, 86, 709-720. doi: 10.1016/j.ijbiomac.2015.11.092 |
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2016 Journal Article Antigen-encoding bone marrow terminates islet-directed memory CD8+ T-cell responses to alleviate islet transplant rejectionColeman, Miranda A., Jessup, Claire F., Bridge, Jennifer A., Overgaard, Nana H., Penko, Daniella, Walters, Stacey, Borg, Danielle J., Galea, Ryan, Forbes, Josephine M., Thomas, Ranjeny, Coates, Patrick T. C., Grey, Shane T., Wells, James W. and Steptoe, Raymond J. (2016). Antigen-encoding bone marrow terminates islet-directed memory CD8+ T-cell responses to alleviate islet transplant rejection. Diabetes, 65 (5), 1328-1340. doi: 10.2337/db15-1418 |
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2016 Conference Publication An Australian prospective cohort of rheumatoid arthritis patients and their first-degree relatives characterising environmental, genetic, microbial and immune factorsBenham, Helen, Wood, John, Nagl, Lisa, Maradana, Muralidhara, Daly, Joshua, Lachner, Nancy, Hugenholtz, Philip and Thomas, Ranjeny (2016). An Australian prospective cohort of rheumatoid arthritis patients and their first-degree relatives characterising environmental, genetic, microbial and immune factors. Australian Rheumatology Association in conjunction with Rheumatology Health Professionals Association, 57th Annual Scientific Meeting, Darwin, NT, Australia, 30 April–4 May 2016. Richmond, VIC, Australia: Wiley-Blackwell Publishing Asia. doi: 10.1111/imj.13052 |
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2016 Conference Publication Restraint of autoreactive T cell expansion is defective in female BALB/c ZAP70(W163C) mutant (SKG) miceRahman, M. A., Montizaan, D., Bhuyan, Z. A., Rehaume, L. M. and Thomas, R. (2016). Restraint of autoreactive T cell expansion is defective in female BALB/c ZAP70(W163C) mutant (SKG) mice. International Congress of Immunology (ICI 2016), Melbourne, Australia, 21-26 August 2016. Weinheim, Germany: Wiley. |
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2016 Conference Publication Collagen specific CD4+T-cells restricted by HLA-DRB1*0101 are selected into the repertoire and expand in disease in mice and patients with inflammatory arthritisJansen, D. T. S. L., Nel, H. J., Ramnoruth, N., Tesiram, J., Nagl, L., Benham, H., Scally, S., Reed, H. H., Rossjohn, J. and Thomas, R. (2016). Collagen specific CD4+T-cells restricted by HLA-DRB1*0101 are selected into the repertoire and expand in disease in mice and patients with inflammatory arthritis. International Congress of Immunology (ICI 2016), Melbourne, Australia, 21-26 August 2016. Weinheim, Germany: Wiley. doi: 10.1002/eji.201670200 |
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2016 Conference Publication Clinician Researchers: Understanding the Barriers and Facilitators for Medical Students and Junior Doctors Considering a Career in ResearchBenham, Helen, Jensen, Charmaine, Thomas, Ranjeny and Eley, Diann (2016). Clinician Researchers: Understanding the Barriers and Facilitators for Medical Students and Junior Doctors Considering a Career in Research. Australian Rheumatology Association in conjunction with Rheumatology Health Professionals Association, 57th Annual Scientific Meeting, Darwin, NT, Australia, 30 April–4 May 2016. HOBOKEN: Wiley. doi: 10.1111/imj.13052 |
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2016 Conference Publication Ablation of pathogenic memory T-cell responses by bone marrow-mediated gene therapy under immune-preserving conditionsSteptoe, R., Al-Kouba, J., Coleman, M., Jessup, C., Starkey, M., Overgaard, N., Bridge, J., Horvat, J., Werder, R., Walters, S., Coates, P. T., Grey, S., Thomas, R., Wells, J., Hansbro, P., Phipps, S. and Davies, J. (2016). Ablation of pathogenic memory T-cell responses by bone marrow-mediated gene therapy under immune-preserving conditions. International Congress of Immunology (ICI 2016), Melbourne, Australia, 21-26 August 2016. Weinheim, Germany: Wiley. |
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2016 Conference Publication Treatment of ZAP-70 Mutant SKG Mice with Anti-IL-23 Antibody Alters Fecal Microbiota Composition and Prevents Outgrowth of Bacteria Associated with Susceptibility to Spondyloarthritis and IleitisRehaume, Linda, Matigian, Nicholas, Kang, Alicia, Zbarskaya, Olga, Kikly, Kristine, Lachner, Nancy, Daly, Joshua, Hugenholtz, Philip, Morrison, Mark, Le Cao, Kim-Anh and Thomas, Ranjeny (2016). Treatment of ZAP-70 Mutant SKG Mice with Anti-IL-23 Antibody Alters Fecal Microbiota Composition and Prevents Outgrowth of Bacteria Associated with Susceptibility to Spondyloarthritis and Ileitis. 2016 ACR/ARHP Annual Meeting, Washington, DC United States, 11–16 November 2016 . Hoboken, NJ United States: Wiley. |
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2016 Conference Publication Development of a model for antigen-specific tolerising immunotherapy and response in NOD miceBuckle, I, Steptoe, R. J., Thomas, R. and Hamilton-Williams, E. E. (2016). Development of a model for antigen-specific tolerising immunotherapy and response in NOD mice. International Congress of Immunology (ICI 2016), Melbourne, Australia, 21-26 August 2016. Weinheim, Germany: Wiley. |
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2016 Conference Publication Oligoclonally expanded CD4+T cells recognising citrulinated vimentin in peripheral blood of rheumatoid arthritis patientsLaw, S. C., Nel, H. J., Scally, S. W., Mehdi, A., Le Cao, K. -A, Rossjohn, J., Reid, H. H., La Gruta, N. L. and Thomas, R. (2016). Oligoclonally expanded CD4+T cells recognising citrulinated vimentin in peripheral blood of rheumatoid arthritis patients. International Congress of Immunology (ICI 2016), Melbourne, Australia, 21-26 August 2016. Weinheim, Germany: Wiley. doi: 10.1002/eji.201670200 |
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2016 Conference Publication Dexamethasone and MPLA treatment of monocyte-derived dendritic cells from rheumatoid arthritis patients induce transcriptional modulation of genes related to cell recruitment, signaling and metabolismGarcia-Gonzalez, P. A., Schinnerling, K., Sepulveda, A., Ubilla-Olguin, G., Soto, L., Neira, O., Medhi, A. M., Nel, H. J., Catalan, D., Thomas, R., Verdugo, R. A. and Aguillon, J. C. (2016). Dexamethasone and MPLA treatment of monocyte-derived dendritic cells from rheumatoid arthritis patients induce transcriptional modulation of genes related to cell recruitment, signaling and metabolism. International Congress of Immunology (ICI 2016), Melbourne, Australia, 21-26 August 2016. Weinheim, Germany: Wiley. |
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2016 Conference Publication Abnormalities of antigen presenting cells in type 1 diabetesBoks, M., Buchanan, K., Nagl, L., Harris, M. and Thomas, R. (2016). Abnormalities of antigen presenting cells in type 1 diabetes. International Congress of Immunology (ICI 2016), Melbourne, Australia, 21-26 August 2016. Weinheim, Germany: Wiley. |
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2016 Conference Publication Molecular basis for the increased susceptibility of Indigenous North American tribes to seropositive rheumatoid arthritisScally, S., Law, S. -C, van Heemst, J., Wieles, D., Moustakis, A., Papadopoulos, G., van der Woude, D., Hitchon, C., Robinson, D., Huizinga, T., Reid, H., Toes, R., El-Gabalawy, H., Rossjohn, J. and Thomas, R. (2016). Molecular basis for the increased susceptibility of Indigenous North American tribes to seropositive rheumatoid arthritis. International Congress of Immunology (ICI 2016), Melbourne, Australia, 21-26 August 2016. Weinheim, Germany: Wiley. doi: 10.1002/eji.201670200 |
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2016 Conference Publication Profiling immunogenic bacteria within the microbiota of SKG mice associated with spondyloarthritis and ileitis using IgA-SEQRehaume, L. M., Kang, A., Zbarskaya, O., Mullaney, J. A., Kim, M., Cuiv, O. P., Angel, N., Lachner, N., Daly, J., Morrison, M., Hugenholtz, P. and Thomas, R. (2016). Profiling immunogenic bacteria within the microbiota of SKG mice associated with spondyloarthritis and ileitis using IgA-SEQ. International Congress of Immunology (ICI 2016), Melbourne, Australia, 21-26 August 2016. Weinheim, Germany: Wiley. |
