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2016 Journal Article Reduced interleukin-2 responsiveness impairs the ability of Treg cells to compete for IL-2 in nonobese diabetic miceJames, Cini R., Buckle, Irina, Muscate, Franziska, Otsuka, Masayuki, Nakao, Mari, Oon, Jack S. H., Steptoe, Raymond J., Thomas, Ranjeny and Hamilton-Williams, Emma E. (2016). Reduced interleukin-2 responsiveness impairs the ability of Treg cells to compete for IL-2 in nonobese diabetic mice. Immunology and Cell Biology, 94 (5), 509-519. doi: 10.1038/icb.2016.7 |
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2016 Conference Publication Abnormalities of antigen presenting cells in type 1 diabetesBoks, M., Buchanan, K., Nagl, L., Harris, M. and Thomas, R. (2016). Abnormalities of antigen presenting cells in type 1 diabetes. International Congress of Immunology (ICI 2016), Melbourne, Australia, 21-26 August 2016. Weinheim, Germany: Wiley. |
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2016 Conference Publication Molecular basis for the increased susceptibility of Indigenous North American tribes to seropositive rheumatoid arthritisScally, S., Law, S. -C, van Heemst, J., Wieles, D., Moustakis, A., Papadopoulos, G., van der Woude, D., Hitchon, C., Robinson, D., Huizinga, T., Reid, H., Toes, R., El-Gabalawy, H., Rossjohn, J. and Thomas, R. (2016). Molecular basis for the increased susceptibility of Indigenous North American tribes to seropositive rheumatoid arthritis. International Congress of Immunology (ICI 2016), Melbourne, Australia, 21-26 August 2016. Weinheim, Germany: Wiley. doi: 10.1002/eji.201670200 |
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2016 Conference Publication Profiling immunogenic bacteria within the microbiota of SKG mice associated with spondyloarthritis and ileitis using IgA-SEQRehaume, L. M., Kang, A., Zbarskaya, O., Mullaney, J. A., Kim, M., Cuiv, O. P., Angel, N., Lachner, N., Daly, J., Morrison, M., Hugenholtz, P. and Thomas, R. (2016). Profiling immunogenic bacteria within the microbiota of SKG mice associated with spondyloarthritis and ileitis using IgA-SEQ. International Congress of Immunology (ICI 2016), Melbourne, Australia, 21-26 August 2016. Weinheim, Germany: Wiley. |
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2016 Conference Publication An Australian prospective cohort of rheumatoid arthritis patients and their first-degree relatives characterising environmental, genetic, microbial and immune factorsBenham, Helen, Wood, John, Nagl, Lisa, Maradana, Muralidhara, Daly, Joshua, Lachner, Nancy, Hugenholtz, Philip and Thomas, Ranjeny (2016). An Australian prospective cohort of rheumatoid arthritis patients and their first-degree relatives characterising environmental, genetic, microbial and immune factors. Australian Rheumatology Association in conjunction with Rheumatology Health Professionals Association, 57th Annual Scientific Meeting, Darwin, NT, Australia, 30 April–4 May 2016. Richmond, VIC, Australia: Wiley-Blackwell Publishing Asia. doi: 10.1111/imj.13052 |
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2016 Conference Publication Restraint of autoreactive T cell expansion is defective in female BALB/c ZAP70(W163C) mutant (SKG) miceRahman, M. A., Montizaan, D., Bhuyan, Z. A., Rehaume, L. M. and Thomas, R. (2016). Restraint of autoreactive T cell expansion is defective in female BALB/c ZAP70(W163C) mutant (SKG) mice. International Congress of Immunology (ICI 2016), Melbourne, Australia, 21-26 August 2016. Weinheim, Germany: Wiley. |
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2016 Conference Publication Collagen specific CD4+T-cells restricted by HLA-DRB1*0101 are selected into the repertoire and expand in disease in mice and patients with inflammatory arthritisJansen, D. T. S. L., Nel, H. J., Ramnoruth, N., Tesiram, J., Nagl, L., Benham, H., Scally, S., Reed, H. H., Rossjohn, J. and Thomas, R. (2016). Collagen specific CD4+T-cells restricted by HLA-DRB1*0101 are selected into the repertoire and expand in disease in mice and patients with inflammatory arthritis. International Congress of Immunology (ICI 2016), Melbourne, Australia, 21-26 August 2016. Weinheim, Germany: Wiley. doi: 10.1002/eji.201670200 |
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2016 Conference Publication Clinician Researchers: Understanding the Barriers and Facilitators for Medical Students and Junior Doctors Considering a Career in ResearchBenham, Helen, Jensen, Charmaine, Thomas, Ranjeny and Eley, Diann (2016). Clinician Researchers: Understanding the Barriers and Facilitators for Medical Students and Junior Doctors Considering a Career in Research. Australian Rheumatology Association in conjunction with Rheumatology Health Professionals Association, 57th Annual Scientific Meeting, Darwin, NT, Australia, 30 April–4 May 2016. HOBOKEN: Wiley. doi: 10.1111/imj.13052 |
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2016 Conference Publication Ablation of pathogenic memory T-cell responses by bone marrow-mediated gene therapy under immune-preserving conditionsSteptoe, R., Al-Kouba, J., Coleman, M., Jessup, C., Starkey, M., Overgaard, N., Bridge, J., Horvat, J., Werder, R., Walters, S., Coates, P. T., Grey, S., Thomas, R., Wells, J., Hansbro, P., Phipps, S. and Davies, J. (2016). Ablation of pathogenic memory T-cell responses by bone marrow-mediated gene therapy under immune-preserving conditions. International Congress of Immunology (ICI 2016), Melbourne, Australia, 21-26 August 2016. Weinheim, Germany: Wiley. |
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2016 Conference Publication Treatment of ZAP-70 Mutant SKG Mice with Anti-IL-23 Antibody Alters Fecal Microbiota Composition and Prevents Outgrowth of Bacteria Associated with Susceptibility to Spondyloarthritis and IleitisRehaume, Linda, Matigian, Nicholas, Kang, Alicia, Zbarskaya, Olga, Kikly, Kristine, Lachner, Nancy, Daly, Joshua, Hugenholtz, Philip, Morrison, Mark, Le Cao, Kim-Anh and Thomas, Ranjeny (2016). Treatment of ZAP-70 Mutant SKG Mice with Anti-IL-23 Antibody Alters Fecal Microbiota Composition and Prevents Outgrowth of Bacteria Associated with Susceptibility to Spondyloarthritis and Ileitis. 2016 ACR/ARHP Annual Meeting, Washington, DC United States, 11–16 November 2016. Hoboken, NJ United States: Wiley. |
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2016 Conference Publication Development of a model for antigen-specific tolerising immunotherapy and response in NOD miceBuckle, I, Steptoe, R. J., Thomas, R. and Hamilton-Williams, E. E. (2016). Development of a model for antigen-specific tolerising immunotherapy and response in NOD mice. International Congress of Immunology (ICI 2016), Melbourne, Australia, 21-26 August 2016. Weinheim, Germany: Wiley. |
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2016 Conference Publication Oligoclonally expanded CD4+T cells recognising citrulinated vimentin in peripheral blood of rheumatoid arthritis patientsLaw, S. C., Nel, H. J., Scally, S. W., Mehdi, A., Le Cao, K. -A, Rossjohn, J., Reid, H. H., La Gruta, N. L. and Thomas, R. (2016). Oligoclonally expanded CD4+T cells recognising citrulinated vimentin in peripheral blood of rheumatoid arthritis patients. International Congress of Immunology (ICI 2016), Melbourne, Australia, 21-26 August 2016. Weinheim, Germany: Wiley. doi: 10.1002/eji.201670200 |
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2016 Conference Publication Dexamethasone and MPLA treatment of monocyte-derived dendritic cells from rheumatoid arthritis patients induce transcriptional modulation of genes related to cell recruitment, signaling and metabolismGarcia-Gonzalez, P. A., Schinnerling, K., Sepulveda, A., Ubilla-Olguin, G., Soto, L., Neira, O., Medhi, A. M., Nel, H. J., Catalan, D., Thomas, R., Verdugo, R. A. and Aguillon, J. C. (2016). Dexamethasone and MPLA treatment of monocyte-derived dendritic cells from rheumatoid arthritis patients induce transcriptional modulation of genes related to cell recruitment, signaling and metabolism. International Congress of Immunology (ICI 2016), Melbourne, Australia, 21-26 August 2016. Weinheim, Germany: Wiley. |
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2015 Journal Article Safety and retention of combination triple disease-modifying anti-rheumatic drugs in new-onset rheumatoid arthritisCummins, L., Katikireddi, V. S., Shankaranarayana, S., Su, K. Y. C., Duggan, E., Videm, V., Pahau, H. and Thomas, R. (2015). Safety and retention of combination triple disease-modifying anti-rheumatic drugs in new-onset rheumatoid arthritis. Internal Medicine Journal, 45 (12), 1266-1273. doi: 10.1111/imj.12896 |
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2015 Conference Publication Profiling at the Single-Cell Level Reveals Evidence for Antigen-Driven Oligoclonal Expansion of Citrullinated Vimentin-Specific CD4+T Cells in Peripheral Blood of Rheumatoid Arthritis (RA) PatientsLaw, Soi Cheng, Nel, Hendrik, Rossjohn, Jamie, Reid, Hugh H., La Gruta, Nicole L. and Thomas, Ranjeny (2015). Profiling at the Single-Cell Level Reveals Evidence for Antigen-Driven Oligoclonal Expansion of Citrullinated Vimentin-Specific CD4+T Cells in Peripheral Blood of Rheumatoid Arthritis (RA) Patients. Annual Meeting of the American-College-of-Rheumatology (ACR) and Association-of-Rheumatology-Health-Professionals (ARHP), San Francisco Ca, Nov 06-11, 2015. HOBOKEN: WILEY-BLACKWELL. |
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2015 Conference Publication The Shared Rheumatoid Arthritis HLA-DRB1 Susceptibility Epitope Shapes the Molecular Orientation of Citrulline and the Autoreactive T Cell Receptor Repertoirevan Heemst, Jurgen, Scally, Stephen, Law, Soi Cheng, van der Woude, Diane, Hitchon, Carol, Robinson, David B., Huizinga, T. W. J., Reid, Hugh H., Toes, Rene E. M., El-Gabalawy, Hani, Rossjohn, Jamie and Thomas, Ranjeny (2015). The Shared Rheumatoid Arthritis HLA-DRB1 Susceptibility Epitope Shapes the Molecular Orientation of Citrulline and the Autoreactive T Cell Receptor Repertoire. Annual Meeting of the American-College-of-Rheumatology (ACR) and Association-of-Rheumatology-Health-Professionals (ARHP), San Francisco Ca, Nov 06-11, 2015. HOBOKEN: WILEY-BLACKWELL. |
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2015 Journal Article Expression profiling pre-diabetic mice to uncover drugs with clinical application to type 1 diabetesPang, Dimeng, Irvine, Katharine M., Mehdi, Ahmed M., Thomas, Helen E., Harris, Mark, Hamilton-Williams, Emma E. and Thomas, Ranjeny (2015). Expression profiling pre-diabetic mice to uncover drugs with clinical application to type 1 diabetes. Clinical and Translational Immunology, 4 (8) e41, e41.1-e41.9. doi: 10.1038/cti.2015.17 |
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2015 Journal Article Coeliac disease and rheumatoid arthritis: similar mechanisms, different antigensKoning, Frits, Thomas, Ranjeny, Rossjohn, Jamie and Toes, Rene E. (2015). Coeliac disease and rheumatoid arthritis: similar mechanisms, different antigens. Nature Reviews Rheumatology, 11 (8), 450-461. doi: 10.1038/nrrheum.2015.59 |
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2015 Journal Article IL-6 driven STAT signalling in circulating CD4+ lymphocytes is a marker for early anti-citrullinated peptide antibody-negative rheumatoid arthritis.Anderson, Amy E., Pratt, Arthur G., Sedhom, Mamdouh A. K., Doran, John Paul, Routledge, Christine, Hargreaves, Ben, Brown, Philip M., Cao, Kim-Anh Le, Isaacs, John D. and Thomas, Ranjeny (2015). IL-6 driven STAT signalling in circulating CD4+ lymphocytes is a marker for early anti-citrullinated peptide antibody-negative rheumatoid arthritis.. Annals of the Rheumatic Diseases, 75 (2), 466-473. doi: 10.1136/annrheumdis-2014-205850 |
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2015 Conference Publication Interleukin-23 Mediates Psoriasis-Like Inflammation in the Skg Mouse Model of SpondyloarthropathyBenham, H., Rehaume, L., Baillet, A., Bhuyan, Z., Bowman, J., Pang, D., Kikly, K., Strutton, G. and Ranjeny, T. (2015). Interleukin-23 Mediates Psoriasis-Like Inflammation in the Skg Mouse Model of Spondyloarthropathy. 56th Annual Scientific Meeting of the Australian Rheumatology Associationin conjunction with Rheumatology Health Professionals Association, Adelaide, SA Australia, 23-26 May 2015. Richmond, VIC Australia: Wiley-Blackwell Publishing Asia. doi: 10.1111/imj.12752 |
