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2019

Journal Article

NKT cell-driven enhancement of antitumor immunity induced by Clec9a-targeted tailorable nanoemulsion

Lam, Pui Yeng, Kobayashi, Takumi, Soon, Megan, Zeng, Bijun, Dolcetti, Riccardo, Leggatt, Graham, Thomas, Ranjeny and Mattarollo, Stephen R. (2019). NKT cell-driven enhancement of antitumor immunity induced by Clec9a-targeted tailorable nanoemulsion. Cancer Immunology Research, 7 (6), 952-962. doi: 10.1158/2326-6066.cir-18-0650

NKT cell-driven enhancement of antitumor immunity induced by Clec9a-targeted tailorable nanoemulsion

2019

Conference Publication

Immune responses to the microbiome tune MHC class II antigen presentation by the intestinal epithelium to control gut pathology

Koyama, Motoko, Mukhopadhyay, Pamela, Schuster, Iona S., Henden, Andrea S., Hülsdünker, Jan, Varelias, Antiopi, Vetizou, Marie, Kuns, Rachel D., Robb, Renee J., Zhang, Ping, Blazar, Bruce R., Thomas, Ranjeny, Begun, Jakob, Waddell, Nicola, Trinchieri, Giorgio, Zeiser, Robert, Clouston, Andrew D., Degli-Esposti, Mariapia A. and Hill, Geoffrey R. (2019). Immune responses to the microbiome tune MHC class II antigen presentation by the intestinal epithelium to control gut pathology. Immunology 2019™ Meeting, San Diego, CA United States, 9-13 May 2019. Rockville, MD United States: American Association of Immunologists. doi: 10.4049/jimmunol.202.supp.69.38

Immune responses to the microbiome tune MHC class II antigen presentation by the intestinal epithelium to control gut pathology

2019

Journal Article

A microfluidic-SERSplatform for isolation and immuno-phenotyping of antigen specific T-cells

Dey, Shuvashis, Vaidyanathan, Ramanathan, Reza, K. Kamil, Wang, Jing, Wang, Yuling, Nel, Hendrik J., Law, Soi-Cheng, Tyler, Jennifer, Rossjohn, Jamie, Reid, Hugh H., Ibn Sina, Abu Ali, Thomas, Ranjeny and Trau, Matt (2019). A microfluidic-SERSplatform for isolation and immuno-phenotyping of antigen specific T-cells. Sensors and Actuators B: Chemical, 284, 281-288. doi: 10.1016/j.snb.2018.12.099

A microfluidic-SERSplatform for isolation and immuno-phenotyping of antigen specific T-cells

2019

Journal Article

Humanized mouse models of rheumatoid arthritis for studies on immunopathogenesis and preclinical testing of cell-based therapies

Schinnerling, Katina, Rosas, Carlos, Soto, Lilian, Thomas, Ranjeny and Carlos Aguillon, Juan (2019). Humanized mouse models of rheumatoid arthritis for studies on immunopathogenesis and preclinical testing of cell-based therapies. Frontiers in Immunology, 10 (FEB) 203, 203. doi: 10.3389/fimmu.2019.00203

Humanized mouse models of rheumatoid arthritis for studies on immunopathogenesis and preclinical testing of cell-based therapies

2019

Journal Article

Cardiorespiratory fitness in patients with rheumatoid arthritis is associated with the patient global assessment but not with objective measurements of disease activity

Liff, Marthe Halsan, Hoff, Mari, Fremo, Thomas, Wisløff, Ulrik, Thomas, Ranjeny and Videm, Vibeke (2019). Cardiorespiratory fitness in patients with rheumatoid arthritis is associated with the patient global assessment but not with objective measurements of disease activity. RMD Open, 5 (1) e000912, e000912. doi: 10.1136/rmdopen-2019-000912

Cardiorespiratory fitness in patients with rheumatoid arthritis is associated with the patient global assessment but not with objective measurements of disease activity

2019

Journal Article

IL-23 favours outgrowth of spondyloarthritis-associated pathobionts and suppresses host support for homeostatic microbiota

Rehaume, Linda M., Matigian, Nicholas, Mehdi, Ahmed M., Lachner, Nancy, Bowerman, Kate L., Daly, Joshua, Lê Cao, Kim-Anh, Hugenholtz, Philip and Thomas, Ranjeny (2019). IL-23 favours outgrowth of spondyloarthritis-associated pathobionts and suppresses host support for homeostatic microbiota. Annals of the Rheumatic Diseases, 78 (4), 494-503. doi: 10.1136/annrheumdis-2018-214381

IL-23 favours outgrowth of spondyloarthritis-associated pathobionts and suppresses host support for homeostatic microbiota

2019

Journal Article

Altered composition and phenotype of mucosal-associated invariant T cells in early untreated rheumatoid arthritis

Koppejan, Hester, Jansen, Diahann T. S. L., Hameetman, Marjolijn, Thomas, Ranjeny, Toes, Rene E. M. and van Gaalen, Floris A. (2019). Altered composition and phenotype of mucosal-associated invariant T cells in early untreated rheumatoid arthritis. Arthritis Research and Therapy, 21 (1) 3, 3. doi: 10.1186/s13075-018-1799-1

Altered composition and phenotype of mucosal-associated invariant T cells in early untreated rheumatoid arthritis

2019

Conference Publication

CD4+CD25+CD127HI cells correlate with length of remission in type 1 diabetes: validated in a multi-site study

Narsale, A., Moya, R., Robertson, H., Payne, D., Lu, T. T., Geoffery, R., Buchanan, K., Harris, M., Bergot, A. S., Thomas, R., Hessner, M., Battaglia, M., Serti, E. and Davies, J. (2019). CD4+CD25+CD127HI cells correlate with length of remission in type 1 diabetes: validated in a multi-site study. International Conference on Lymphocyte Engineering (ICLE), London, United Kingdom, 13-15 September 2019. New Rochelle, NY United States: Mary Ann Liebert. doi: 10.1089/hum.2019.29091.abstracts

CD4+CD25+CD127HI cells correlate with length of remission in type 1 diabetes: validated in a multi-site study

2019

Conference Publication

A phase I, randomized, double-blind, placebo-controlled, single center, single-dose escalation to investigate the safety, tolerability, and pharmacodynamics of subcutaneously administered DEN-181 in adult patients with ACPA plus rheumatoid arthritis on stable methotrexate

Sonigra, Amee, Nel, Hendrik, Ramnoruth, Nishta, Talekar, Meghna, Tesiram, Joanne, Stuurman, Frederik, Proctor, Lavinia, Roberts, Helen, Thurmond, Robin, Vecchio, Phillip, Gourley, Ian, Rigby, Mark, Felix, Nathan, Becart, Stephane, Campbell, Kim and Thomas, Ranjeny (2019). A phase I, randomized, double-blind, placebo-controlled, single center, single-dose escalation to investigate the safety, tolerability, and pharmacodynamics of subcutaneously administered DEN-181 in adult patients with ACPA plus rheumatoid arthritis on stable methotrexate. 2019 ACR/ARP Annual Meeting, Atlanta, GA, United States, 8 - 13 November 2019. Hoboken, NJ, United States: John Wiley & Sons.

A phase I, randomized, double-blind, placebo-controlled, single center, single-dose escalation to investigate the safety, tolerability, and pharmacodynamics of subcutaneously administered DEN-181 in adult patients with ACPA plus rheumatoid arthritis on stable methotrexate

2018

Journal Article

An improved clinical model to predict stimulated C-peptide in children with recent-onset type 1 diabetes

Buchanan, Kerry, Mehdi, Ahmed M, Hughes, Ian, Cotterill, Andrew, Le Cao, Kim-Anh, Thomas, Ranjeny and Harris, Mark (2018). An improved clinical model to predict stimulated C-peptide in children with recent-onset type 1 diabetes. Pediatric Diabetes, 20 (2), 166-171. doi: 10.1111/pedi.12808

An improved clinical model to predict stimulated C-peptide in children with recent-onset type 1 diabetes

2018

Journal Article

Dendritic cells, T cells and their interaction in rheumatoid arthritis : Dendritic cells, T cells and their interaction

Wehr, P., Purvis, H., Law, S.-C. and Thomas, R. (2018). Dendritic cells, T cells and their interaction in rheumatoid arthritis : Dendritic cells, T cells and their interaction. Clinical and Experimental Immunology, 196 (1), 12-27. doi: 10.1111/cei.13256

Dendritic cells, T cells and their interaction in rheumatoid arthritis : Dendritic cells, T cells and their interaction

2018

Journal Article

The SKG model of spondyloarthritis

Rahman, M. Arifur and Thomas, Ranjeny (2018). The SKG model of spondyloarthritis. Best Practice and Research: Clinical Rheumatology, 30 (6), 1-15. doi: 10.1016/j.berh.2018.07.004

The SKG model of spondyloarthritis

2018

Journal Article

Pro-inflammatory CX3CR1 CD59 TL1A IL-23 monocytes are expanded in patients with Ankylosing Spondylitis and modulate ILC3 immune functions

Ciccia, Francesco, Guggino, Giuliana, Zeng, Michael, Thomas, Ranjeny, Ranganathan, Vidya, Rahman, Arifur, Alessandro, Riccardo, Rizzo, Aroldo, Saieva, Laura, Macaluso, Federica, Peralta, Sergio, Di Liberto, Diana, Dieli, Francesco, Cipriani, Paola, Giacomelli, Roberto, Baeten, Dominique and Haroon, Nigil (2018). Pro-inflammatory CX3CR1 CD59 TL1A IL-23 monocytes are expanded in patients with Ankylosing Spondylitis and modulate ILC3 immune functions. Arthritis & Rheumatology, 70 (12), 2003-2013. doi: 10.1002/art.40582

Pro-inflammatory CX3CR1 CD59 TL1A IL-23 monocytes are expanded in patients with Ankylosing Spondylitis and modulate ILC3 immune functions

2018

Journal Article

Treatment delays for patients with new onset rheumatoid arthritis presenting to an Australian early arthritis clinic

Ison, Matthew, Duggan, Emily, Mehdi, Ahmed, Thomas, Ranjeny and Benham, Helen (2018). Treatment delays for patients with new onset rheumatoid arthritis presenting to an Australian early arthritis clinic. Internal Medicine Journal, 48 (12), 1498-1504. doi: 10.1111/imj.13972

Treatment delays for patients with new onset rheumatoid arthritis presenting to an Australian early arthritis clinic

2018

Journal Article

Autoimmune-mediated thymic atrophy is accelerated but reversible in RelB-deficient mice

O'Sullivan, Brendan J., Yekollu, Suman, Ruscher, Roland, Mehdi, Ahmed M., Maradana, Muralidhara Rao, Chidgey, Ann P. and Thomas, Ranjeny (2018). Autoimmune-mediated thymic atrophy is accelerated but reversible in RelB-deficient mice. Frontiers in Immunology, 9 (MAY) 1092, 1092. doi: 10.3389/fimmu.2018.01092

Autoimmune-mediated thymic atrophy is accelerated but reversible in RelB-deficient mice

2018

Journal Article

Flow Cytometric Clinical Immunomonitoring Using Peptide-MHC Class II Tetramers: Optimization of Methods and Protocol Development

Jansen, Diahann T. S. L., Ramnoruth, Nishta, Loh, Khai L., Rossjohn, Jamie, Reid, Hugh H., Nel, Hendrik J. and Thomas, Ranjeny (2018). Flow Cytometric Clinical Immunomonitoring Using Peptide-MHC Class II Tetramers: Optimization of Methods and Protocol Development. Frontiers in Immunology, 9 (JAN) 8, 1-10. doi: 10.3389/fimmu.2018.00008

Flow Cytometric Clinical Immunomonitoring Using Peptide-MHC Class II Tetramers: Optimization of Methods and Protocol Development

2018

Journal Article

The interplay between citrullination and HLA-DRB1 polymorphism in shaping peptide binding hierarchies in rheumatoid arthritis

Ting, Yi Tian, Petersen, Jan, Ramarathinam, Sri H., Scally, Stephen W., Loh, Khai L., Thomas, Ranjeny, Suri, Anish, Baker, Daniel G., Purcell, Anthony W., Reid, Hugh H. and Rossjohn, Jamie (2018). The interplay between citrullination and HLA-DRB1 polymorphism in shaping peptide binding hierarchies in rheumatoid arthritis. The Journal of Biological Chemistry, 293 (9), 3236-3251. doi: 10.1074/jbc.RA117.001013

The interplay between citrullination and HLA-DRB1 polymorphism in shaping peptide binding hierarchies in rheumatoid arthritis

2018

Conference Publication

Cardiorespiratory fitness in patients with rheumatoid arthritis

Liff, M. H., Hoff, M., Fremo, T., Wisloff, U., Thomas, R. and Videm, V. (2018). Cardiorespiratory fitness in patients with rheumatoid arthritis. Congress of the European League Against Rheumatism (EULAR), Amsterdam, Netherlands, 13-16 June 2018. London, United Kingdom: BMJ Group. doi: 10.1136/annrheumdis-2018-eular.5497

Cardiorespiratory fitness in patients with rheumatoid arthritis

2018

Conference Publication

Pre-clinical clonally-expanded aggrecan89-103-specific CD4+T cells are a target for autoimmune arthritis prevention

Wehr, Pascale, Nel, Hendrik, Law, Soi Cheng, Jansen, Diahann, La Gruta, Nicole, Reid, Hugh, Rossjohn, Jamie and Thomas, Ranjeny (2018). Pre-clinical clonally-expanded aggrecan89-103-specific CD4+T cells are a target for autoimmune arthritis prevention. 2018 ACR/ARHP Annual Meeting, Chicago, Il United States, 19-24 October 2018. Hoboken, NJ United States: John Wiley & Sons.

Pre-clinical clonally-expanded aggrecan89-103-specific CD4+T cells are a target for autoimmune arthritis prevention

2018

Conference Publication

Antigen-Specific CD4 regulation by Liposomes encapsulating calcitriol and ChgA mimotope in NOD mice

Bergot, A. S., Buckle,, Wright, C., Talekar, M., Hamilton-Williams, E. and Thomas, R. (2018). Antigen-Specific CD4 regulation by Liposomes encapsulating calcitriol and ChgA mimotope in NOD mice. 15th International Symposium on Dendritic Cells (DC), Aachen, Germany, 10-14 June 2018. Hoboken, NJ, United States: Wiley. doi: 10.1002/eji.201871000

Antigen-Specific CD4 regulation by Liposomes encapsulating calcitriol and ChgA mimotope in NOD mice