2020 Journal Article RelB suppresses type I Interferon signaling in dendritic cellsSaha, Irene, Jaiswal, Hemant, Mishra, Richa, Nel, Hendrik J., Schreuder, Jaring, Kaushik, Monika, Singh Chauhan, Kuldeep, Singh Rawat, Bhupendra, Thomas, Ranjeny, Naik, Shalin, Kumar, Himanshu and Tailor, Prafullakumar (2020). RelB suppresses type I Interferon signaling in dendritic cells. Cellular Immunology, 349 104043, 104043. doi: 10.1016/j.cellimm.2020.104043 |
2020 Journal Article Regulatory T cells induced by single-peptide liposome immunotherapy suppress islet-Specific T cell responses to multiple antigens and protect from autoimmune diabetesBergot, Anne-Sophie, Buckle, Irina, Cikaluru, Sumana, Naranjo, Jennifer Loaiza, Wright, Casey Maree, Zheng, Guoliang, Talekar, Meghna, Hamilton-Williams, Emma E. and Thomas, Ranjeny (2020). Regulatory T cells induced by single-peptide liposome immunotherapy suppress islet-Specific T cell responses to multiple antigens and protect from autoimmune diabetes. Journal of Immunology, 204 (7), ji1901128-1797. doi: 10.4049/jimmunol.1901128 |
2020 Journal Article Mortality is increased in patients with rheumatoid arthritis or diabetes compared to the general population – the Nord-Trøndelag health studyHouge, Ingrid Sæther, Hoff, Mari, Thomas, Ranjeny and Videm, Vibeke (2020). Mortality is increased in patients with rheumatoid arthritis or diabetes compared to the general population – the Nord-Trøndelag health study. Scientific Reports, 10 (1) 3593, 3593. doi: 10.1038/s41598-020-60621-2 |
2019 Journal Article MHC class II antigen presentation by the intestinal epithelium initiates graft-versus-host disease and is influenced by the microbiotaKoyama, Motoko, Mukhopadhyay, Pamela, Schuster, Iona S., Henden, Andrea S., Hülsdünker, Jan, Varelias, Antiopi, Vetizou, Marie, Kuns, Rachel D., Robb, Renee J., Zhang, Ping, Blazar, Bruce B., Thomas, Ranjeny, Begun, Jakob, Waddell, Nicola, Trinchieri, Giorgio, Zeiser, Robert, Clouston, Andrew D., Degli-Esposti, Mariapia A. and Hill, Geoffrey R. (2019). MHC class II antigen presentation by the intestinal epithelium initiates graft-versus-host disease and is influenced by the microbiota. Immunity, 51 (5), 885-898. doi: 10.1016/j.immuni.2019.08.011 |
2019 Journal Article PD-L1 and calcitriol dependent liposomal antigen-specific regulation of systemic inflammatory autoimmune diseaseGalea, Ryan, Nel, Hendrik, Talekar, Meghna, Liu, Xiao, Ooi, Joshua D., Huynh, Megan, Hadjigol, Sara, Robson, Kate J., Ting, Yi Tian, Cole, Suzanne, Cochlin, Karyn, Hitchcock, Shannon, Zeng, Bijun, Yekollu, Suman, Boks, Martine, Goh, Natalie, Roberts, Helen, Rossjohn, Jamie, Reid, Hugh H., Boyd, Ben J., Malaviya, Ravi, Shealy, David J., Baker, Daniel G., Madakamutil, Loui, Kitching, A. Richard, O’Sullivan, Brendan J. and Thomas, Ranjeny (2019). PD-L1 and calcitriol dependent liposomal antigen-specific regulation of systemic inflammatory autoimmune disease. JCI Insight, 4 (18) e126025. doi: 10.1172/jci.insight.126025 |
2019 Conference Publication COMPARISON OF MORTALITY IN RHEUMATOID ARTHRITIS AND DIABETES - THE HUNT POPULATION-BASED STUDYHouge, Ingrid Saether, Hoff, Mari, Thomas, Ranjeny and Videm, Vibeke (2019). COMPARISON OF MORTALITY IN RHEUMATOID ARTHRITIS AND DIABETES - THE HUNT POPULATION-BASED STUDY. Annual European Congress of Rheumatology (EULAR), Madrid Spain, Jun 12-15, 2019. LONDON: BMJ PUBLISHING GROUP. doi: 10.1136/annrheumdis-2019-eular.1781 |
2019 Journal Article Regulation of tolerogenic features on dexamethasone-modulated MPLA-activated dendritic cells by MYCGarcia-Gonzalez, Paulina A., Maggi, Jaxaira, Schinnerling, Katina, Sepulveda-Gutierrez, Alejandro, Soto, Lilian, Neire, Oscar, Mehdi, Ahmed M., Nel, Hendrik J., Pesce, Barbara, Aravena, Octavio, Carmen Molina, Maria, Catalan, Diego, Thomas, Ranjeny, Verdugo, Ricardo A. and Carlos Aguillon, Juan (2019). Regulation of tolerogenic features on dexamethasone-modulated MPLA-activated dendritic cells by MYC. Frontiers in Immunology, 10 (MAY) 1171, 1171. doi: 10.3389/fimmu.2019.01171 |
2019 Journal Article NKT cell-driven enhancement of antitumor immunity induced by Clec9a-targeted tailorable nanoemulsionLam, Pui Yeng, Kobayashi, Takumi, Soon, Megan, Zeng, Bijun, Dolcetti, Riccardo, Leggatt, Graham, Thomas, Ranjeny and Mattarollo, Stephen R. (2019). NKT cell-driven enhancement of antitumor immunity induced by Clec9a-targeted tailorable nanoemulsion. Cancer Immunology Research, 7 (6), 952-962. doi: 10.1158/2326-6066.cir-18-0650 |
2019 Conference Publication Immune responses to the microbiome tune MHC class II antigen presentation by the intestinal epithelium to control gut pathologyKoyama, Motoko, Mukhopadhyay, Pamela, Schuster, Iona S., Henden, Andrea S., Hülsdünker, Jan, Varelias, Antiopi, Vetizou, Marie, Kuns, Rachel D., Robb, Renee J., Zhang, Ping, Blazar, Bruce R., Thomas, Ranjeny, Begun, Jakob, Waddell, Nicola, Trinchieri, Giorgio, Zeiser, Robert, Clouston, Andrew D., Degli-Esposti, Mariapia A. and Hill, Geoffrey R. (2019). Immune responses to the microbiome tune MHC class II antigen presentation by the intestinal epithelium to control gut pathology. Immunology 2019™ Meeting, San Diego, CA United States, 9-13 May 2019. Rockville, MD United States: American Association of Immunologists. doi: 10.4049/jimmunol.202.supp.69.38 |
2019 Journal Article A microfluidic-SERSplatform for isolation and immuno-phenotyping of antigen specific T-cellsDey, Shuvashis, Vaidyanathan, Ramanathan, Reza, K. Kamil, Wang, Jing, Wang, Yuling, Nel, Hendrik J., Law, Soi-Cheng, Tyler, Jennifer, Rossjohn, Jamie, Reid, Hugh H., Ibn Sina, Abu Ali, Thomas, Ranjeny and Trau, Matt (2019). A microfluidic-SERSplatform for isolation and immuno-phenotyping of antigen specific T-cells. Sensors and Actuators B: Chemical, 284, 281-288. doi: 10.1016/j.snb.2018.12.099 |
2019 Journal Article Humanized mouse models of rheumatoid arthritis for studies on immunopathogenesis and preclinical testing of cell-based therapiesSchinnerling, Katina, Rosas, Carlos, Soto, Lilian, Thomas, Ranjeny and Carlos Aguillon, Juan (2019). Humanized mouse models of rheumatoid arthritis for studies on immunopathogenesis and preclinical testing of cell-based therapies. Frontiers in Immunology, 10 (FEB) 203, 203. doi: 10.3389/fimmu.2019.00203 |
2019 Journal Article Cardiorespiratory fitness in patients with rheumatoid arthritis is associated with the patient global assessment but not with objective measurements of disease activityLiff, Marthe Halsan, Hoff, Mari, Fremo, Thomas, Wisløff, Ulrik, Thomas, Ranjeny and Videm, Vibeke (2019). Cardiorespiratory fitness in patients with rheumatoid arthritis is associated with the patient global assessment but not with objective measurements of disease activity. RMD Open, 5 (1) e000912, e000912. doi: 10.1136/rmdopen-2019-000912 |
2019 Journal Article IL-23 favours outgrowth of spondyloarthritis-associated pathobionts and suppresses host support for homeostatic microbiotaRehaume, Linda M., Matigian, Nicholas, Mehdi, Ahmed M., Lachner, Nancy, Bowerman, Kate L., Daly, Joshua, Lê Cao, Kim-Anh, Hugenholtz, Philip and Thomas, Ranjeny (2019). IL-23 favours outgrowth of spondyloarthritis-associated pathobionts and suppresses host support for homeostatic microbiota. Annals of the Rheumatic Diseases, 78 (4), 494-503. doi: 10.1136/annrheumdis-2018-214381 |
2019 Journal Article Altered composition and phenotype of mucosal-associated invariant T cells in early untreated rheumatoid arthritisKoppejan, Hester, Jansen, Diahann T. S. L., Hameetman, Marjolijn, Thomas, Ranjeny, Toes, Rene E. M. and van Gaalen, Floris A. (2019). Altered composition and phenotype of mucosal-associated invariant T cells in early untreated rheumatoid arthritis. Arthritis Research and Therapy, 21 (1) 3, 3. doi: 10.1186/s13075-018-1799-1 |
2019 Conference Publication A phase I, randomized, double-blind, placebo-controlled, single center, single-dose escalation to investigate the safety, tolerability, and pharmacodynamics of subcutaneously administered DEN-181 in adult patients with ACPA plus rheumatoid arthritis on stable methotrexateSonigra, Amee, Nel, Hendrik, Ramnoruth, Nishta, Talekar, Meghna, Tesiram, Joanne, Stuurman, Frederik, Proctor, Lavinia, Roberts, Helen, Thurmond, Robin, Vecchio, Phillip, Gourley, Ian, Rigby, Mark, Felix, Nathan, Becart, Stephane, Campbell, Kim and Thomas, Ranjeny (2019). A phase I, randomized, double-blind, placebo-controlled, single center, single-dose escalation to investigate the safety, tolerability, and pharmacodynamics of subcutaneously administered DEN-181 in adult patients with ACPA plus rheumatoid arthritis on stable methotrexate. 2019 ACR/ARP Annual Meeting, Atlanta, GA, United States, 8 - 13 November 2019. Hoboken, NJ, United States: John Wiley & Sons. |
2019 Conference Publication CD4+CD25+CD127HI cells correlate with length of remission in type 1 diabetes: validated in a multi-site studyNarsale, A., Moya, R., Robertson, H., Payne, D., Lu, T. T., Geoffery, R., Buchanan, K., Harris, M., Bergot, A. S., Thomas, R., Hessner, M., Battaglia, M., Serti, E. and Davies, J. (2019). CD4+CD25+CD127HI cells correlate with length of remission in type 1 diabetes: validated in a multi-site study. International Conference on Lymphocyte Engineering (ICLE), London, United Kingdom, 13-15 September 2019. New Rochelle, NY United States: Mary Ann Liebert. doi: 10.1089/hum.2019.29091.abstracts |
2018 Journal Article An improved clinical model to predict stimulated C-peptide in children with recent-onset type 1 diabetesBuchanan, Kerry, Mehdi, Ahmed M, Hughes, Ian, Cotterill, Andrew, Le Cao, Kim-Anh, Thomas, Ranjeny and Harris, Mark (2018). An improved clinical model to predict stimulated C-peptide in children with recent-onset type 1 diabetes. Pediatric Diabetes, 20 (2), 166-171. doi: 10.1111/pedi.12808 |
2018 Journal Article Dendritic cells, T cells and their interaction in rheumatoid arthritis : Dendritic cells, T cells and their interactionWehr, P., Purvis, H., Law, S.-C. and Thomas, R. (2018). Dendritic cells, T cells and their interaction in rheumatoid arthritis : Dendritic cells, T cells and their interaction. Clinical and Experimental Immunology, 196 (1), 12-27. doi: 10.1111/cei.13256 |
2018 Journal Article The SKG model of spondyloarthritisRahman, M. Arifur and Thomas, Ranjeny (2018). The SKG model of spondyloarthritis. Best Practice and Research: Clinical Rheumatology, 30 (6), 1-15. doi: 10.1016/j.berh.2018.07.004 |
2018 Journal Article Pro-inflammatory CX3CR1 CD59 TL1A IL-23 monocytes are expanded in patients with Ankylosing Spondylitis and modulate ILC3 immune functionsCiccia, Francesco, Guggino, Giuliana, Zeng, Michael, Thomas, Ranjeny, Ranganathan, Vidya, Rahman, Arifur, Alessandro, Riccardo, Rizzo, Aroldo, Saieva, Laura, Macaluso, Federica, Peralta, Sergio, Di Liberto, Diana, Dieli, Francesco, Cipriani, Paola, Giacomelli, Roberto, Baeten, Dominique and Haroon, Nigil (2018). Pro-inflammatory CX3CR1 CD59 TL1A IL-23 monocytes are expanded in patients with Ankylosing Spondylitis and modulate ILC3 immune functions. Arthritis & Rheumatology, 70 (12), 2003-2013. doi: 10.1002/art.40582 |