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2019

Journal Article

Altered composition and phenotype of mucosal-associated invariant T cells in early untreated rheumatoid arthritis

Koppejan, Hester, Jansen, Diahann T. S. L., Hameetman, Marjolijn, Thomas, Ranjeny, Toes, Rene E. M. and van Gaalen, Floris A. (2019). Altered composition and phenotype of mucosal-associated invariant T cells in early untreated rheumatoid arthritis. Arthritis Research and Therapy, 21 (1) 3, 3. doi: 10.1186/s13075-018-1799-1

Altered composition and phenotype of mucosal-associated invariant T cells in early untreated rheumatoid arthritis

2019

Conference Publication

A phase I, randomized, double-blind, placebo-controlled, single center, single-dose escalation to investigate the safety, tolerability, and pharmacodynamics of subcutaneously administered DEN-181 in adult patients with ACPA plus rheumatoid arthritis on stable methotrexate

Sonigra, Amee, Nel, Hendrik, Ramnoruth, Nishta, Talekar, Meghna, Tesiram, Joanne, Stuurman, Frederik, Proctor, Lavinia, Roberts, Helen, Thurmond, Robin, Vecchio, Phillip, Gourley, Ian, Rigby, Mark, Felix, Nathan, Becart, Stephane, Campbell, Kim and Thomas, Ranjeny (2019). A phase I, randomized, double-blind, placebo-controlled, single center, single-dose escalation to investigate the safety, tolerability, and pharmacodynamics of subcutaneously administered DEN-181 in adult patients with ACPA plus rheumatoid arthritis on stable methotrexate. 2019 ACR/ARP Annual Meeting, Atlanta, GA, United States, 8 - 13 November 2019. Hoboken, NJ, United States: John Wiley & Sons.

A phase I, randomized, double-blind, placebo-controlled, single center, single-dose escalation to investigate the safety, tolerability, and pharmacodynamics of subcutaneously administered DEN-181 in adult patients with ACPA plus rheumatoid arthritis on stable methotrexate

2019

Conference Publication

CD4+CD25+CD127HI cells correlate with length of remission in type 1 diabetes: validated in a multi-site study

Narsale, A., Moya, R., Robertson, H., Payne, D., Lu, T. T., Geoffery, R., Buchanan, K., Harris, M., Bergot, A. S., Thomas, R., Hessner, M., Battaglia, M., Serti, E. and Davies, J. (2019). CD4+CD25+CD127HI cells correlate with length of remission in type 1 diabetes: validated in a multi-site study. International Conference on Lymphocyte Engineering (ICLE), London, United Kingdom, 13-15 September 2019. New Rochelle, NY United States: Mary Ann Liebert. doi: 10.1089/hum.2019.29091.abstracts

CD4+CD25+CD127HI cells correlate with length of remission in type 1 diabetes: validated in a multi-site study

2018

Journal Article

An improved clinical model to predict stimulated C-peptide in children with recent-onset type 1 diabetes

Buchanan, Kerry, Mehdi, Ahmed M, Hughes, Ian, Cotterill, Andrew, Le Cao, Kim-Anh, Thomas, Ranjeny and Harris, Mark (2018). An improved clinical model to predict stimulated C-peptide in children with recent-onset type 1 diabetes. Pediatric Diabetes, 20 (2), 166-171. doi: 10.1111/pedi.12808

An improved clinical model to predict stimulated C-peptide in children with recent-onset type 1 diabetes

2018

Journal Article

Dendritic cells, T cells and their interaction in rheumatoid arthritis : Dendritic cells, T cells and their interaction

Wehr, P., Purvis, H., Law, S.-C. and Thomas, R. (2018). Dendritic cells, T cells and their interaction in rheumatoid arthritis : Dendritic cells, T cells and their interaction. Clinical and Experimental Immunology, 196 (1), 12-27. doi: 10.1111/cei.13256

Dendritic cells, T cells and their interaction in rheumatoid arthritis : Dendritic cells, T cells and their interaction

2018

Journal Article

The SKG model of spondyloarthritis

Rahman, M. Arifur and Thomas, Ranjeny (2018). The SKG model of spondyloarthritis. Best Practice and Research: Clinical Rheumatology, 30 (6), 1-15. doi: 10.1016/j.berh.2018.07.004

The SKG model of spondyloarthritis

2018

Journal Article

Pro-inflammatory CX3CR1 CD59 TL1A IL-23 monocytes are expanded in patients with Ankylosing Spondylitis and modulate ILC3 immune functions

Ciccia, Francesco, Guggino, Giuliana, Zeng, Michael, Thomas, Ranjeny, Ranganathan, Vidya, Rahman, Arifur, Alessandro, Riccardo, Rizzo, Aroldo, Saieva, Laura, Macaluso, Federica, Peralta, Sergio, Di Liberto, Diana, Dieli, Francesco, Cipriani, Paola, Giacomelli, Roberto, Baeten, Dominique and Haroon, Nigil (2018). Pro-inflammatory CX3CR1 CD59 TL1A IL-23 monocytes are expanded in patients with Ankylosing Spondylitis and modulate ILC3 immune functions. Arthritis & Rheumatology, 70 (12), 2003-2013. doi: 10.1002/art.40582

Pro-inflammatory CX3CR1 CD59 TL1A IL-23 monocytes are expanded in patients with Ankylosing Spondylitis and modulate ILC3 immune functions

2018

Journal Article

Treatment delays for patients with new onset rheumatoid arthritis presenting to an Australian early arthritis clinic

Ison, Matthew, Duggan, Emily, Mehdi, Ahmed, Thomas, Ranjeny and Benham, Helen (2018). Treatment delays for patients with new onset rheumatoid arthritis presenting to an Australian early arthritis clinic. Internal Medicine Journal, 48 (12), 1498-1504. doi: 10.1111/imj.13972

Treatment delays for patients with new onset rheumatoid arthritis presenting to an Australian early arthritis clinic

2018

Journal Article

Autoimmune-mediated thymic atrophy is accelerated but reversible in RelB-deficient mice

O'Sullivan, Brendan J., Yekollu, Suman, Ruscher, Roland, Mehdi, Ahmed M., Maradana, Muralidhara Rao, Chidgey, Ann P. and Thomas, Ranjeny (2018). Autoimmune-mediated thymic atrophy is accelerated but reversible in RelB-deficient mice. Frontiers in Immunology, 9 (MAY) 1092, 1092. doi: 10.3389/fimmu.2018.01092

Autoimmune-mediated thymic atrophy is accelerated but reversible in RelB-deficient mice

2018

Journal Article

Flow Cytometric Clinical Immunomonitoring Using Peptide-MHC Class II Tetramers: Optimization of Methods and Protocol Development

Jansen, Diahann T. S. L., Ramnoruth, Nishta, Loh, Khai L., Rossjohn, Jamie, Reid, Hugh H., Nel, Hendrik J. and Thomas, Ranjeny (2018). Flow Cytometric Clinical Immunomonitoring Using Peptide-MHC Class II Tetramers: Optimization of Methods and Protocol Development. Frontiers in Immunology, 9 (JAN) 8, 1-10. doi: 10.3389/fimmu.2018.00008

Flow Cytometric Clinical Immunomonitoring Using Peptide-MHC Class II Tetramers: Optimization of Methods and Protocol Development

2018

Journal Article

The interplay between citrullination and HLA-DRB1 polymorphism in shaping peptide binding hierarchies in rheumatoid arthritis

Ting, Yi Tian, Petersen, Jan, Ramarathinam, Sri H., Scally, Stephen W., Loh, Khai L., Thomas, Ranjeny, Suri, Anish, Baker, Daniel G., Purcell, Anthony W., Reid, Hugh H. and Rossjohn, Jamie (2018). The interplay between citrullination and HLA-DRB1 polymorphism in shaping peptide binding hierarchies in rheumatoid arthritis. The Journal of Biological Chemistry, 293 (9), 3236-3251. doi: 10.1074/jbc.RA117.001013

The interplay between citrullination and HLA-DRB1 polymorphism in shaping peptide binding hierarchies in rheumatoid arthritis

2018

Conference Publication

Antigen-Specific CD4 regulation by Liposomes encapsulating calcitriol and ChgA mimotope in NOD mice

Bergot, A. S., Buckle,, Wright, C., Talekar, M., Hamilton-Williams, E. and Thomas, R. (2018). Antigen-Specific CD4 regulation by Liposomes encapsulating calcitriol and ChgA mimotope in NOD mice. 15th International Symposium on Dendritic Cells (DC), Aachen, Germany, 10-14 June 2018. Hoboken, NJ, United States: Wiley. doi: 10.1002/eji.201871000

Antigen-Specific CD4 regulation by Liposomes encapsulating calcitriol and ChgA mimotope in NOD mice

2018

Conference Publication

Towards T cell tolerance in rheumatoid arthritis

Thomas, R. (2018). Towards T cell tolerance in rheumatoid arthritis. Congress of the European League Against Rheumatism (EULAR), Amsterdam, Netherlands, 13-16 June 2018. London, United Kingdom: BMJ Group. doi: 10.1136/annrheumdis-2018-eular.7793

Towards T cell tolerance in rheumatoid arthritis

2018

Conference Publication

Intestinal inflammatory regulation in murine and human spondyloarthropathy requires high-affinity T cell receptor-zeta chain-associated protein (ZAP) 70-mediated runt-related transcription factor (Runx) 3 activity

Bhuyan, Zaied Ahmed, Rahman, M. Arifur, Maradana, Muralidhara, Mehdi, Ahmed, Guggino, Giuliana, Leo, Paul, Rehaume, Linda, Brown, Matthew, Ciccia, Francesco and Thomas, Ranjeny (2018). Intestinal inflammatory regulation in murine and human spondyloarthropathy requires high-affinity T cell receptor-zeta chain-associated protein (ZAP) 70-mediated runt-related transcription factor (Runx) 3 activity. 2018 ACR/ARHP Annual Meeting, Chicago, Illinois, 19-24 October 2018. Hoboken, NJ, United States: John Wiley & Sons.

Intestinal inflammatory regulation in murine and human spondyloarthropathy requires high-affinity T cell receptor-zeta chain-associated protein (ZAP) 70-mediated runt-related transcription factor (Runx) 3 activity

2018

Journal Article

Immunomodulatory liposomes targeting liver macrophages arrest progression of nonalcoholic steatohepatitis

Maradana, Muralidhara Rao, Yekollu, Suman Kumar, Zeng, Bijun, Ellis, Jonathan, Clouston, Andrew, Miller, Gregory, Talekar, Meghna, Bhuyan, Zaied Ahmed, Mahadevaiah, Sachin, Powell, Elizabeth E., Irvine, Katharine M., Thomas, Ranjeny and O'Sullivan, Brendan John (2018). Immunomodulatory liposomes targeting liver macrophages arrest progression of nonalcoholic steatohepatitis. Metabolism: Clinical and Experimental, 78, 80-94. doi: 10.1016/j.metabol.2017.09.002

Immunomodulatory liposomes targeting liver macrophages arrest progression of nonalcoholic steatohepatitis

2018

Conference Publication

The Australian arthritis and autoimmune biobank collabortive (A3BC) protocol

March, L., Willers, C., Ellis, J., Cobb, J., Lester, S., Buchbinder, R., Wechalekar, M., Munro, J., Benham, H., Jackson, C., Xue, M., Hill, C., Kenna, T., Keen, H., Perera, C., Hassett, G., Singh-Grewal, D., Richards, B., Lassere, M., Youssef, P., Lim,, Walsh, P., Thomas, R., Brown, M., Adib, N., Barrett, C., Ng, J., Rischmueller, M., Boros, C. ... Murray, K. (2018). The Australian arthritis and autoimmune biobank collabortive (A3BC) protocol. Australian Rheumatology Association Annual Scientific Meeting with the Rheumatology Health Professionals Association, Melbourne, VIC, Australia, 5 - 8 May 2018. Richmond, VIC, Australia: Wiley-Blackwell Publishing Asia. doi: 10.1111/imj.13772

The Australian arthritis and autoimmune biobank collabortive (A3BC) protocol

2018

Conference Publication

Cardiorespiratory fitness in patients with rheumatoid arthritis

Liff, M. H., Hoff, M., Fremo, T., Wisloff, U., Thomas, R. and Videm, V. (2018). Cardiorespiratory fitness in patients with rheumatoid arthritis. Congress of the European League Against Rheumatism (EULAR), Amsterdam, Netherlands, 13-16 June 2018. London, United Kingdom: BMJ Group. doi: 10.1136/annrheumdis-2018-eular.5497

Cardiorespiratory fitness in patients with rheumatoid arthritis

2018

Conference Publication

Pre-clinical clonally-expanded aggrecan89-103-specific CD4+T cells are a target for autoimmune arthritis prevention

Wehr, Pascale, Nel, Hendrik, Law, Soi Cheng, Jansen, Diahann, La Gruta, Nicole, Reid, Hugh, Rossjohn, Jamie and Thomas, Ranjeny (2018). Pre-clinical clonally-expanded aggrecan89-103-specific CD4+T cells are a target for autoimmune arthritis prevention. 2018 ACR/ARHP Annual Meeting, Chicago, Il United States, 19-24 October 2018. Hoboken, NJ United States: John Wiley & Sons.

Pre-clinical clonally-expanded aggrecan89-103-specific CD4+T cells are a target for autoimmune arthritis prevention

2017

Journal Article

What will it take? Pathways, time and funding: Australian medical students' perspective on clinician-scientist training

Eley, Diann S., Jensen, Charmaine, Thomas, Ranjeny and Benham, Helen (2017). What will it take? Pathways, time and funding: Australian medical students' perspective on clinician-scientist training. BMC Medical Education, 14 (242) 242, 242. doi: 10.1186/s12909-017-1081-2

What will it take? Pathways, time and funding: Australian medical students' perspective on clinician-scientist training

2017

Journal Article

Dexamethasone and monophosphoryl lipid a induce a distinctive profile on monocyte-derived dendritic cells through transcriptional modulation of genes associated with essential processes of the immune response

Garcia-Gonzalez, Paulina A., Schinnerling, Katina, Sepulveda-Gutierrez, Alejandro, Maggi, Jaxaira, Mehdi, Ahmed M., Nel, Hendrik J., Pesce, Barbara, Larrondo, Milton L., Aravena, Octavio, Molina, Mar-A C., Catalan, Diego, Thomas, Ranjeny, Verdugo, Ricardo A. and Aguillon, Juan C. (2017). Dexamethasone and monophosphoryl lipid a induce a distinctive profile on monocyte-derived dendritic cells through transcriptional modulation of genes associated with essential processes of the immune response. Frontiers in Immunology, 8 (OCT) 1350, 1350. doi: 10.3389/fimmu.2017.01350

Dexamethasone and monophosphoryl lipid a induce a distinctive profile on monocyte-derived dendritic cells through transcriptional modulation of genes associated with essential processes of the immune response