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2023

Conference Publication

Goblet cell specific anti-apoptotic role of interleukin-24 in spondyloarthritis-associated ileitis

Cameron, Amy, Giri, Rabina, Begun, Jakob, Wells, Timothy, Thomas, Ranjeny and Bergot, Anne-Sophie (2023). Goblet cell specific anti-apoptotic role of interleukin-24 in spondyloarthritis-associated ileitis. ACR Convergence 2023, San Diego, CA, United States, 10 - 15 November 2023. Hoboken, NJ, United States: John Wiley & Sons.

Goblet cell specific anti-apoptotic role of interleukin-24 in spondyloarthritis-associated ileitis

2023

Conference Publication

Goblet cell specific anti-apoptotic role of interleukin-24 in spondyloarthritis-associated ileitis

Cameron, A., Giri, R., Begun, J., Wells, T., Bergot, A. S. and Thomas, R. (2023). Goblet cell specific anti-apoptotic role of interleukin-24 in spondyloarthritis-associated ileitis. EULAR 2023 European Congress of Rheumatology, Milan, Italy, 31 May-3 June 2023. London, United Kingdom: BMJ Group. doi: 10.1136/annrheumdis-2023-eular.1346

Goblet cell specific anti-apoptotic role of interleukin-24 in spondyloarthritis-associated ileitis

2023

Journal Article

Reinforcing the Checkpoint in Rheumatoid Arthritis

Gravallese, Ellen M. and Thomas, Ranjeny (2023). Reinforcing the Checkpoint in Rheumatoid Arthritis. The New England journal of medicine, 388 (20), 1905-1907. doi: 10.1056/NEJMe2300734

Reinforcing the Checkpoint in Rheumatoid Arthritis

2023

Conference Publication

INCREASED ENDOTHELIAL PROTEIN C RECEPTOR CORRELATES WITH DISEASE ACTIVITY AND INFLAMMATORY CYTOKINES IN RHEUMATOID AND PSORIATIC ARTHRITIS PATIENTS

Xue, Meilang, Lin, Haiyan, Lynch, Tom, Bereza-Malcolm, Lara, Sinnathurai, Premarani, Thomas, Ranjeny, Keen, Helen, Hill, Catherine, Lester, Susan, Wechalekar, Mihir and March, Lyn (2023). INCREASED ENDOTHELIAL PROTEIN C RECEPTOR CORRELATES WITH DISEASE ACTIVITY AND INFLAMMATORY CYTOKINES IN RHEUMATOID AND PSORIATIC ARTHRITIS PATIENTS. HOBOKEN: WILEY.

INCREASED ENDOTHELIAL PROTEIN C RECEPTOR CORRELATES WITH DISEASE ACTIVITY AND INFLAMMATORY CYTOKINES IN RHEUMATOID AND PSORIATIC ARTHRITIS PATIENTS

2023

Conference Publication

UPDATE ON NATIONAL RECRUITMENT FOR THE AUSTRALIAN ARTHRITIS AND AUTOIMMUNE BIOBANK COLLABORATIVE BIOBANK & REGISTRY FOR RHEUMATIC DISEASES

Lynch, Tom, Thomas, Ranjeny, Keen, Helen, Hill, Catherine, Lester, Susan, Wechalekar, Mihir, Lassere, Marissa, Buchbinder, Rachelle, Munro, Jane, Singh-Grewal, Davinder, Sinnathurai, Premarani, Xue, Meilang, Lightowler, Daniel, McInnes, Linda, Bereza-Malcolm, Lara, Lin, Haiyan, Cross, Marita, Chand, Vibhasha, Yi, Jie, Grivei, Anca, Herd, Karen, Roch, Michelle, Tuli, Jannatul, Briggs, Liz, Weedon, Helen and March, Lyn (2023). UPDATE ON NATIONAL RECRUITMENT FOR THE AUSTRALIAN ARTHRITIS AND AUTOIMMUNE BIOBANK COLLABORATIVE BIOBANK & REGISTRY FOR RHEUMATIC DISEASES. HOBOKEN: WILEY.

UPDATE ON NATIONAL RECRUITMENT FOR THE AUSTRALIAN ARTHRITIS AND AUTOIMMUNE BIOBANK COLLABORATIVE BIOBANK & REGISTRY FOR RHEUMATIC DISEASES

2023

Conference Publication

The interplay of IL-23, probiotic and pathobiont bacteria in the pathogenesis of ileitis and spondyloarthritis in the SKG mouse model

Bergot, Anne-Sophie, Cai, Benjamin, Giri, Rabina, Cameron, Amy, Duggan, Emily, Lim, Kai, Rehaume, Linda, Morrison, Mark, Begun, Jakob and Thomas, Ranjeny (2023). The interplay of IL-23, probiotic and pathobiont bacteria in the pathogenesis of ileitis and spondyloarthritis in the SKG mouse model. 2023 Australian Rheumatology Association (ARA) 63rd Annual Scientific Meeting, Hobart, TAS, Australia, 6–9 May 2023. Hoboken, NJ, United States: Wiley.

The interplay of IL-23, probiotic and pathobiont bacteria in the pathogenesis of ileitis and spondyloarthritis in the SKG mouse model

2023

Conference Publication

A pilot blended-delivery wellbeing and healthy lifestyle program for adults with rheumatoid arthritis

Thomas, Ranjeny, Burton, Nicola, Mayr, Hannah, Chachay, Veronique, Sweeney, Aoife, Hollis, Kely, Gartner, Coral and Coombs, Jeff (2023). A pilot blended-delivery wellbeing and healthy lifestyle program for adults with rheumatoid arthritis. 2023 Australian Rheumatology Association (ARA) 63rd Annual Scientific Meeting, Hobart, TAS Australia, 6–9 May 2023. Richmond, VIC Australia: John Wiley & Sons.

A pilot blended-delivery wellbeing and healthy lifestyle program for adults with rheumatoid arthritis

2023

Journal Article

Antigen specific immunotherapy to restore antigen-specific tolerance in type 1 diabetes and Graves’ disease

Zala, Aakansha and Thomas, Ranjeny (2023). Antigen specific immunotherapy to restore antigen-specific tolerance in type 1 diabetes and Graves’ disease. Clinical and Experimental Immunology, 211 (2), 164-175. doi: 10.1093/cei/uxac115

Antigen specific immunotherapy to restore antigen-specific tolerance in type 1 diabetes and Graves’ disease

2023

Journal Article

Genetically encoded Runx3 and CD4+ intestinal epithelial lymphocyte deficiencies link SKG mouse and human predisposition to spondyloarthropathy

Bhuyan, Zaied Ahmed, Rahman, M. Arifur, Maradana, Muralidhara Rao, Mehdi, Ahmed M., Bergot, Anne-Sophie, Simone, Davide, El-Kurdi, Marya, Garrido-Mesa, Jose, Cai, Cheng Bang Benjamin, Cameron, Amy J., Hanson, Aimee L., Nel, Hendrik J., Kenna, Tony, Leo, Paul, Rehaume, Linda, Brown, Matthew A., Ciccia, Francesco and Thomas, Ranjeny (2023). Genetically encoded Runx3 and CD4+ intestinal epithelial lymphocyte deficiencies link SKG mouse and human predisposition to spondyloarthropathy. Clinical Immunology, 247 109220, 1-14. doi: 10.1016/j.clim.2022.109220

Genetically encoded Runx3 and CD4+ intestinal epithelial lymphocyte deficiencies link SKG mouse and human predisposition to spondyloarthropathy

2022

Journal Article

Environmental pathways affecting gene expression (E.PAGE) as an R package to predict gene–environment associations

Muralidharan, Sachin, Ali, Sarah, Yang, Lilin, Badshah, Joshua, Zahir, Syeda Farah, Ali, Rubbiya A., Chandra, Janin, Frazer, Ian H., Thomas, Ranjeny and Mehdi, Ahmed M. (2022). Environmental pathways affecting gene expression (E.PAGE) as an R package to predict gene–environment associations. Scientific Reports, 12 (1) 18710, 1-19. doi: 10.1038/s41598-022-21988-6

Environmental pathways affecting gene expression (E.PAGE) as an R package to predict gene–environment associations

2022

Journal Article

Randomized phase I trial of antigen-specific tolerizing immunotherapy with peptide/calcitriol liposomes in ACPA+ rheumatoid arthritis

Sonigra, Amee, Nel, Hendrik J., Wehr, Pascale, Ramnoruth, Nishta, Patel, Swati, van Schie, Karin A., Bladen, Maxwell W., Mehdi, Ahmed M., Tesiram, Joanne, Talekar, Meghna, Rossjohn, Jamie, Reid, Hugh H., Stuurman, Frederik E., Roberts, Helen, Vecchio, Phillip, Gourley, Ian, Rigby, Mark, Becart, Stephane, Toes, Rene E.M., Scherer, Hans Ulrich, Lê Cao, Kim-Anh, Campbell, Kim and Thomas, Ranjeny (2022). Randomized phase I trial of antigen-specific tolerizing immunotherapy with peptide/calcitriol liposomes in ACPA+ rheumatoid arthritis. JCI Insight, 7 (20) e160964, 1-18. doi: 10.1172/jci.insight.160964

Randomized phase I trial of antigen-specific tolerizing immunotherapy with peptide/calcitriol liposomes in ACPA+ rheumatoid arthritis

2022

Other Outputs

High Chlamydia burden promotes TNF-dependent reactive arthritis in SKG mice

Baillet, Athan and Thomas, Ranjeny (2022). High Chlamydia burden promotes TNF-dependent reactive arthritis in SKG mice. The University of Queensland. (Dataset) doi: 10.48610/6de8d54

High Chlamydia burden promotes TNF-dependent reactive arthritis in SKG mice

2022

Conference Publication

A Positive-feedback Model for the Contribution of Virus-Specific T Cells to the Development of Rheumatoid Arthritis

Nel, H., Wehr, P., Andoniou, C., Schuster, I., Gras, S., McGuire, H., Weedon, H., Small, A., Lowe, K., Degli-Esposti M., Wechalekar M. and Thomas R. (2022). A Positive-feedback Model for the Contribution of Virus-Specific T Cells to the Development of Rheumatoid Arthritis. ACR Convergence 2022, Philadelphia, PA, United States, 10-14 November 2022. Hoboken, NJ, United States: John Wiley & Sons. doi: 10.1002/art.42355

A Positive-feedback Model for the Contribution of Virus-Specific T Cells to the Development of Rheumatoid Arthritis

2022

Journal Article

Global epidemiology of rheumatoid arthritis

Finckh, Axel, Gilbert, Benoît, Hodkinson, Bridget, Bae, Sang-Cheol, Thomas, Ranjeny, Deane, Kevin D., Alpizar-Rodriguez, Deshiré and Lauper, Kim (2022). Global epidemiology of rheumatoid arthritis. Nature Reviews Rheumatology, 18 (10), 591-602. doi: 10.1038/s41584-022-00827-y

Global epidemiology of rheumatoid arthritis

2022

Journal Article

Immune tolerance therapies for autoimmune diseases: shifting the goalpost to cure

Sharkey, Patrick and Thomas, Ranjeny (2022). Immune tolerance therapies for autoimmune diseases: shifting the goalpost to cure. Current Opinion in Pharmacology, 65 102242, 102242. doi: 10.1016/j.coph.2022.102242

Immune tolerance therapies for autoimmune diseases: shifting the goalpost to cure

2022

Journal Article

Secreted NF-κB suppressive microbial metabolites modulate gut inflammation

Giri, Rabina, Hoedt, Emily C., Khushi, Shamsunnahar, Salim, Angela A., Bergot, Anne-Sophie, Schreiber, Veronika, Thomas, Ranjeny, McGuckin, Michael A., Florin, Timothy H., Morrison, Mark, Capon, Robert J., Ó Cuív, Páraic and Begun, Jakob (2022). Secreted NF-κB suppressive microbial metabolites modulate gut inflammation. Cell Reports, 39 (2) 110646, 110646. doi: 10.1016/j.celrep.2022.110646

Secreted NF-κB suppressive microbial metabolites modulate gut inflammation

2022

Journal Article

Evaluation of a fit-for-purpose assay to monitor antigen-specific functional CD4+ T-cell subpopulations in rheumatoid arthritis using flow cytometry-based peptide-MHC class-II tetramer staining

Patel, Swati, Ramnoruth, Nishta, Wehr, Pascale, Rossjohn, Jamie, Reid, Hugh H., Campbell, Kim, Nel, Hendrik J. and Thomas, Ranjeny (2022). Evaluation of a fit-for-purpose assay to monitor antigen-specific functional CD4+ T-cell subpopulations in rheumatoid arthritis using flow cytometry-based peptide-MHC class-II tetramer staining. Clinical and Experimental Immunology, 207 (1), 72-83. doi: 10.1093/cei/uxab008

Evaluation of a fit-for-purpose assay to monitor antigen-specific functional CD4+ T-cell subpopulations in rheumatoid arthritis using flow cytometry-based peptide-MHC class-II tetramer staining

2022

Other Outputs

E.PAGE: A curated database and enrichment tool to predict gene modules associated with gene-environment interactions

Muralidharan, Sachin, Ali, Sarah, Yang, Lilin, Badshah, Joshua, Zahir, Farah, Ali, Rubbiya, Chandra, Janin, Thomas, Ranjeny and Mehdi, Ahmed M. (2022). E.PAGE: A curated database and enrichment tool to predict gene modules associated with gene-environment interactions. doi: 10.1101/2022.01.03.474848

E.PAGE: A curated database and enrichment tool to predict gene modules associated with gene-environment interactions

2022

Journal Article

Tolerance induction by liposomes targeting a single CD8 epitope IGRP in a model of type 1 diabetes is impeded by co-targeting a CD4 islet epitope

Buckle, Irina, Loaiza Naranjo, Jeniffer D., Bergot, Anne-Sophie, Zhang, Vivian, Talekar, Meghna, Steptoe, Raymond J., Thomas, Ranjeny and Hamilton-Williams, Emma E. (2022). Tolerance induction by liposomes targeting a single CD8 epitope IGRP in a model of type 1 diabetes is impeded by co-targeting a CD4 islet epitope. Immunology and Cell Biology, 100 (1), 33-48. doi: 10.1111/imcb.12506

Tolerance induction by liposomes targeting a single CD8 epitope IGRP in a model of type 1 diabetes is impeded by co-targeting a CD4 islet epitope

2021

Journal Article

IL-6 receptor blockade does not slow β cell loss in new-onset type 1 diabetes

Greenbaum, Carla J., Serti, Elisavet, Lambert, Katharina, Weiner, Lia J., Kanaparthi, Sai, Lord, Sandra, Gitelman, Stephen E., Wilson, Darrell M., Gaglia, Jason L., Griffin, Kurt J., Russell, William E., Raskin, Philip, Moran, Antoinette, Willi, Steven M., Tsalikian, Eva, DiMeglio, Linda A., Herold, Kevan C., Moore, Wayne V., Goland, Robin, Harris, Mark, Craig, Maria E., Schatz, Desmond A., Baidal, David A., Rodriguez, Henry, Utzschneider, Kristina M., Nel, Hendrik J., Soppe, Carol L., Boyle, Karen D., Cerosaletti, Karen ... Sanda, Srinath (2021). IL-6 receptor blockade does not slow β cell loss in new-onset type 1 diabetes. JCI Insight, 6 (21) e150074. doi: 10.1172/jci.insight.150074

IL-6 receptor blockade does not slow β cell loss in new-onset type 1 diabetes