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2010 Journal Article The balancing act of autoimmunity: Central and peripheral tolerance versus infection controlThomas, Ranjeny (2010). The balancing act of autoimmunity: Central and peripheral tolerance versus infection control. International Reviews of Immunology, 29 (2), 211-233. doi: 10.3109/08830180903434219 |
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2010 Journal Article A physiological function of inflammation-associated SerpinB2 is regulation of adaptive immunitySchroder, Wayne A., Le, Thuy T. T., Major, Lee, Street, Shayna, Gardner, Joy, Lambley, Eleanore, Markey, Kate, MacDonald, Kelli P., Fish, Richard J., Thomas, Ranjeny and Suhrbier, Andreas (2010). A physiological function of inflammation-associated SerpinB2 is regulation of adaptive immunity. Journal of Immunology, 184 (5), 2663-2670. doi: 10.4049/jimmunol.0902187 |
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2010 Journal Article Targeting antigen to diverse APCs inactivates memory CD8+ T cells without eliciting tissue-destructive effector functionKenna, Tony J., Waldie, Tanya, McNally, Alice, Thomson, Meagan, Yagita, Hideo, Thomas, Ranjeny and Steptoe, Raymond J. (2010). Targeting antigen to diverse APCs inactivates memory CD8+ T cells without eliciting tissue-destructive effector function. Journal of Immunology, 184 (2), 598-606. doi: 10.4049/jimmunol.0900032 |
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2010 Conference Publication F.72. IL-1 beta produced in response to islet autoantigen presentation differentiates T-helper-17 cells at the expense of regulatory T cells: Implications for the timing of tolerizing immunotherapyBertin-Maghit, Sebastien, O'Sullivan, Brendan, Best, Shannoiin, Duggan, Emily, Pang, Dimeng, Thomas, Helen, Kay, Thomas, Harrison, Leonard, Steptoe, Raymond and Thomas, Ranjeny (2010). F.72. IL-1 beta produced in response to islet autoantigen presentation differentiates T-helper-17 cells at the expense of regulatory T cells: Implications for the timing of tolerizing immunotherapy. FOCiS 2010: Tenth Annual Meeting of the Federation of Clinical Immunology Societies, Boston, MA, U.S.A., 24-27 June 2010. Orlando, FL, U.S.A.: Academic Press. doi: 10.1016/j.clim.2010.03.294 |
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2010 Conference Publication Autoreactive T cells Eescaping thymic deletion in REL-B deficient mice depend on dendritic cell-encoded REL-B for control of autoimmunityO'Sullivan, B, Pai, S, Street, S, MacDonald, K, Gerondakis, S, Hill, G and Thomas, R (2010). Autoreactive T cells Eescaping thymic deletion in REL-B deficient mice depend on dendritic cell-encoded REL-B for control of autoimmunity. 10th Annual Meeting of the Federation-of-Clinical-Immunology-Societies, Boston, MA, U.S.A., 24-27 June 2010. Maryland Heights, MO, U.S.A.: Academic Press. doi: 10.1016/j.clim.2010.03.407 |
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2010 Conference Publication F.25. Activity of the REL-B and p65 subunits of NF-kappa B demonstrates innate immune activation in children at risk of type 1 diabetesPai, S, Best, S, Roddick, J, Pahao, H, Baskerville, T, Brown, M, Harris, M, Cotterill, A and Thomas, R (2010). F.25. Activity of the REL-B and p65 subunits of NF-kappa B demonstrates innate immune activation in children at risk of type 1 diabetes. FOCiS 2010: Tenth Annual Meeting of the Federation of Clinical Immunology Societies, Boston, MA, U.S.A., 24-27 June 2010. Orlando, FL, U.S.A.: Academic Press. doi: 10.1016/j.clim.2010.03.247 |
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2009 Journal Article c-Rel is required for the development of thymic Foxp3(+) CD4 regulatory T cellsIsomura, I., Palmer, S., Grumont, R. J., Bunting, K., Hoyne, G., Wilkinson, N., Banerjee, A., Proietto, A., Gugasyan, R., Li, W., McNally, Alice, Steptoe, Raymond J., Thomas, Ranjeny, Shannon, F. and Gerondakis, S. (2009). c-Rel is required for the development of thymic Foxp3(+) CD4 regulatory T cells. The Journal of Experimental Medicine, 206 (13), 3001-3014. doi: 10.1084/jem.20091411 |
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2009 Book Chapter Dendritic CellsPai, Saparna and Thomas, Ranjeny (2009). Dendritic Cells. Rheumatoid Arthritis. (pp. 116-123) Elsevier Inc.. doi: 10.1016/B978-032305475-1.50021-5 |
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2009 Journal Article Steady-state dendritic cells continuously inactivate T cells that escape thymic negative selectionDoan, Tracy, McNally, Alice, Thomas, Ranjeny and Steptoe, Raymond (2009). Steady-state dendritic cells continuously inactivate T cells that escape thymic negative selection. Immunology and Cell Biology, 87 (8), 615-622. doi: 10.1038/icb.2009.46 |
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2009 Journal Article Inflammation predicts accelerated brachial arterial wall changes in patients with recent-onset rheumatoid arthritisHannawi, Suad, Marwick, Thomas and Thomas, Ranjeny (2009). Inflammation predicts accelerated brachial arterial wall changes in patients with recent-onset rheumatoid arthritis. Arthritis Research and Therapy, 11 (2) R51, R51.1-R51.7. doi: 10.1186/ar2668 |
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2009 Journal Article Serum levels of soluble receptor for advanced glycation end products and of S100 proteins are associated with inflammatory, autoantibody, and classical risk markers of joint and vascular damage in rheumatoid arthritisChen, Yueh-Sheng, Yan, Weixing, Geczy, Carolyn L., Brown, Matthew A. and Thomas, Ranjeny (2009). Serum levels of soluble receptor for advanced glycation end products and of S100 proteins are associated with inflammatory, autoantibody, and classical risk markers of joint and vascular damage in rheumatoid arthritis. Arthritis Research and Therapy, 11 (2) R39, R39 .1-R39 .11. doi: 10.1186/ar2645 |
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2008 Conference Publication RelB response to LPS: Characterizing the molecular mechanism of abnormal DC function in Type 1 DiabetesPai, S., Best, S. E., Mollah, Z. U., Prins, J., Brown, M. and Thomas, R. (2008). RelB response to LPS: Characterizing the molecular mechanism of abnormal DC function in Type 1 Diabetes. Annual Congress of the British-Society-of-Immunology, Glasgow Scotland, Nov 17-21, 2008. |
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2008 Journal Article Immune deficiency or hyperactivity-Nf-κb illuminates autoimmunityPai, Saparna and Thomas, Ranjeny (2008). Immune deficiency or hyperactivity-Nf-κb illuminates autoimmunity. Journal of Autoimmunity, 31 (3), 245-251. doi: 10.1016/j.jaut.2008.04.012 |
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2008 Journal Article High avidity autoreactive T cells with a low signalling capacity through the T-cell receptor: central to rheumatoid arthritis pathogenesis?Thomas, Ranjeny, Turner, Malcolm and Cope, Andrew P. (2008). High avidity autoreactive T cells with a low signalling capacity through the T-cell receptor: central to rheumatoid arthritis pathogenesis?. Arthritis Research and Therapy, 10 (4) 210, 1-9. doi: 10.1186/ar2446 |
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2008 Journal Article Abnormal NF-kappa B function characterizes human type 1 diabetes dendritic cells and monocytesMollah, Zia U.A., Pai, Saparna, Craig Moore, O'Sullivan, Brendan J., Harrison, Matthew J., Peng, Judy, Phillips, Karen, Prins, Johannes B., Cardinal, John and Thomas, Ranjeny (2008). Abnormal NF-kappa B function characterizes human type 1 diabetes dendritic cells and monocytes. Journal of Immunology, 180 (5), 3166-3175. doi: 10.4049/jimmunol.180.5.3166 |
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2008 Journal Article Steady-state dendritic cells expressing cognate antgen terminate memory CD8+ T-cell responsesKenna, Tony J., Thomas, Ranjeny and Steptoe, Raymond J. (2008). Steady-state dendritic cells expressing cognate antgen terminate memory CD8+ T-cell responses. Blood, 111 (4), 2091-2100. doi: 10.1182/blood-2007-07-103200 |
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2008 Book Chapter Dendritic CellsPai, Saparna and Thomas, Ranjeny (2008). Dendritic Cells. Rheumatoid Arthritis. (pp. 116-123) Elsevier. doi: 10.1016/B978-032305475-1.50021-5 |
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2007 Journal Article Atherosclerotic disease is increased in recent onset rheumatoid arthritis: a critical role for inflammationHannawi, Suad, Haluska, Brian, Marwick, Thomas H. and Thomas, Ranjeny (2007). Atherosclerotic disease is increased in recent onset rheumatoid arthritis: a critical role for inflammation. Arthritis Research and Therapy, 9 (6) R116, R116.1-R116.9. doi: 10.1186/ar2323 |
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2007 Journal Article Cells of the synovium in rheumatoid arthritis: dendritic cellsLutzky, Viviana, Suad Hannawi, Suad and Thomas, Ranjeny (2007). Cells of the synovium in rheumatoid arthritis: dendritic cells. Arthritis Research and Therapy, 9 (4) 219, 219-230. doi: 10.1186/ar2200 |
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2007 Journal Article Plasmodium strain determines dendritic cell function essential for survival from malariaWykes, Michelle N., Liu, Xue Q., Beattie, Lynette, Stanisic, Danielle I., Stacey, Katryn J., Smyth, Mark J., Thomas, Ranjeny and Good, Michael F. (2007). Plasmodium strain determines dendritic cell function essential for survival from malaria. PLoS Pathogens, 3 (7), e96-0904-e96-0912. doi: 10.1371/journal.ppat.0030096 |