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2010

Journal Article

The balancing act of autoimmunity: Central and peripheral tolerance versus infection control

Thomas, Ranjeny (2010). The balancing act of autoimmunity: Central and peripheral tolerance versus infection control. International Reviews of Immunology, 29 (2), 211-233. doi: 10.3109/08830180903434219

The balancing act of autoimmunity: Central and peripheral tolerance versus infection control

2010

Journal Article

A physiological function of inflammation-associated SerpinB2 is regulation of adaptive immunity

Schroder, Wayne A., Le, Thuy T. T., Major, Lee, Street, Shayna, Gardner, Joy, Lambley, Eleanore, Markey, Kate, MacDonald, Kelli P., Fish, Richard J., Thomas, Ranjeny and Suhrbier, Andreas (2010). A physiological function of inflammation-associated SerpinB2 is regulation of adaptive immunity. Journal of Immunology, 184 (5), 2663-2670. doi: 10.4049/jimmunol.0902187

A physiological function of inflammation-associated SerpinB2 is regulation of adaptive immunity

2010

Journal Article

Targeting antigen to diverse APCs inactivates memory CD8+ T cells without eliciting tissue-destructive effector function

Kenna, Tony J., Waldie, Tanya, McNally, Alice, Thomson, Meagan, Yagita, Hideo, Thomas, Ranjeny and Steptoe, Raymond J. (2010). Targeting antigen to diverse APCs inactivates memory CD8+ T cells without eliciting tissue-destructive effector function. Journal of Immunology, 184 (2), 598-606. doi: 10.4049/jimmunol.0900032

Targeting antigen to diverse APCs inactivates memory CD8+ T cells without eliciting tissue-destructive effector function

2010

Conference Publication

F.72. IL-1 beta produced in response to islet autoantigen presentation differentiates T-helper-17 cells at the expense of regulatory T cells: Implications for the timing of tolerizing immunotherapy

Bertin-Maghit, Sebastien, O'Sullivan, Brendan, Best, Shannoiin, Duggan, Emily, Pang, Dimeng, Thomas, Helen, Kay, Thomas, Harrison, Leonard, Steptoe, Raymond and Thomas, Ranjeny (2010). F.72. IL-1 beta produced in response to islet autoantigen presentation differentiates T-helper-17 cells at the expense of regulatory T cells: Implications for the timing of tolerizing immunotherapy. FOCiS 2010: Tenth Annual Meeting of the Federation of Clinical Immunology Societies, Boston, MA, U.S.A., 24-27 June 2010. Orlando, FL, U.S.A.: Academic Press. doi: 10.1016/j.clim.2010.03.294

F.72. IL-1 beta produced in response to islet autoantigen presentation differentiates T-helper-17 cells at the expense of regulatory T cells: Implications for the timing of tolerizing immunotherapy

2010

Conference Publication

Autoreactive T cells Eescaping thymic deletion in REL-B deficient mice depend on dendritic cell-encoded REL-B for control of autoimmunity

O'Sullivan, B, Pai, S, Street, S, MacDonald, K, Gerondakis, S, Hill, G and Thomas, R (2010). Autoreactive T cells Eescaping thymic deletion in REL-B deficient mice depend on dendritic cell-encoded REL-B for control of autoimmunity. 10th Annual Meeting of the Federation-of-Clinical-Immunology-Societies, Boston, MA, U.S.A., 24-27 June 2010. Maryland Heights, MO, U.S.A.: Academic Press. doi: 10.1016/j.clim.2010.03.407

Autoreactive T cells Eescaping thymic deletion in REL-B deficient mice depend on dendritic cell-encoded REL-B for control of autoimmunity

2010

Conference Publication

F.25. Activity of the REL-B and p65 subunits of NF-kappa B demonstrates innate immune activation in children at risk of type 1 diabetes

Pai, S, Best, S, Roddick, J, Pahao, H, Baskerville, T, Brown, M, Harris, M, Cotterill, A and Thomas, R (2010). F.25. Activity of the REL-B and p65 subunits of NF-kappa B demonstrates innate immune activation in children at risk of type 1 diabetes. FOCiS 2010: Tenth Annual Meeting of the Federation of Clinical Immunology Societies, Boston, MA, U.S.A., 24-27 June 2010. Orlando, FL, U.S.A.: Academic Press. doi: 10.1016/j.clim.2010.03.247

F.25. Activity of the REL-B and p65 subunits of NF-kappa B demonstrates innate immune activation in children at risk of type 1 diabetes

2009

Journal Article

c-Rel is required for the development of thymic Foxp3(+) CD4 regulatory T cells

Isomura, I., Palmer, S., Grumont, R. J., Bunting, K., Hoyne, G., Wilkinson, N., Banerjee, A., Proietto, A., Gugasyan, R., Li, W., McNally, Alice, Steptoe, Raymond J., Thomas, Ranjeny, Shannon, F. and Gerondakis, S. (2009). c-Rel is required for the development of thymic Foxp3(+) CD4 regulatory T cells. The Journal of Experimental Medicine, 206 (13), 3001-3014. doi: 10.1084/jem.20091411

c-Rel is required for the development of thymic Foxp3(+) CD4 regulatory T cells

2009

Book Chapter

Dendritic Cells

Pai, Saparna and Thomas, Ranjeny (2009). Dendritic Cells. Rheumatoid Arthritis. (pp. 116-123) Elsevier Inc.. doi: 10.1016/B978-032305475-1.50021-5

Dendritic Cells

2009

Journal Article

Steady-state dendritic cells continuously inactivate T cells that escape thymic negative selection

Doan, Tracy, McNally, Alice, Thomas, Ranjeny and Steptoe, Raymond (2009). Steady-state dendritic cells continuously inactivate T cells that escape thymic negative selection. Immunology and Cell Biology, 87 (8), 615-622. doi: 10.1038/icb.2009.46

Steady-state dendritic cells continuously inactivate T cells that escape thymic negative selection

2009

Journal Article

Inflammation predicts accelerated brachial arterial wall changes in patients with recent-onset rheumatoid arthritis

Hannawi, Suad, Marwick, Thomas and Thomas, Ranjeny (2009). Inflammation predicts accelerated brachial arterial wall changes in patients with recent-onset rheumatoid arthritis. Arthritis Research and Therapy, 11 (2) R51, R51.1-R51.7. doi: 10.1186/ar2668

Inflammation predicts accelerated brachial arterial wall changes in patients with recent-onset rheumatoid arthritis

2009

Journal Article

Serum levels of soluble receptor for advanced glycation end products and of S100 proteins are associated with inflammatory, autoantibody, and classical risk markers of joint and vascular damage in rheumatoid arthritis

Chen, Yueh-Sheng, Yan, Weixing, Geczy, Carolyn L., Brown, Matthew A. and Thomas, Ranjeny (2009). Serum levels of soluble receptor for advanced glycation end products and of S100 proteins are associated with inflammatory, autoantibody, and classical risk markers of joint and vascular damage in rheumatoid arthritis. Arthritis Research and Therapy, 11 (2) R39, R39 .1-R39 .11. doi: 10.1186/ar2645

Serum levels of soluble receptor for advanced glycation end products and of S100 proteins are associated with inflammatory, autoantibody, and classical risk markers of joint and vascular damage in rheumatoid arthritis

2008

Conference Publication

RelB response to LPS: Characterizing the molecular mechanism of abnormal DC function in Type 1 Diabetes

Pai, S., Best, S. E., Mollah, Z. U., Prins, J., Brown, M. and Thomas, R. (2008). RelB response to LPS: Characterizing the molecular mechanism of abnormal DC function in Type 1 Diabetes. Annual Congress of the British-Society-of-Immunology, Glasgow Scotland, Nov 17-21, 2008.

RelB response to LPS: Characterizing the molecular mechanism of abnormal DC function in Type 1 Diabetes

2008

Journal Article

Immune deficiency or hyperactivity-Nf-κb illuminates autoimmunity

Pai, Saparna and Thomas, Ranjeny (2008). Immune deficiency or hyperactivity-Nf-κb illuminates autoimmunity. Journal of Autoimmunity, 31 (3), 245-251. doi: 10.1016/j.jaut.2008.04.012

Immune deficiency or hyperactivity-Nf-κb illuminates autoimmunity

2008

Journal Article

High avidity autoreactive T cells with a low signalling capacity through the T-cell receptor: central to rheumatoid arthritis pathogenesis?

Thomas, Ranjeny, Turner, Malcolm and Cope, Andrew P. (2008). High avidity autoreactive T cells with a low signalling capacity through the T-cell receptor: central to rheumatoid arthritis pathogenesis?. Arthritis Research and Therapy, 10 (4) 210, 1-9. doi: 10.1186/ar2446

High avidity autoreactive T cells with a low signalling capacity through the T-cell receptor: central to rheumatoid arthritis pathogenesis?

2008

Journal Article

Abnormal NF-kappa B function characterizes human type 1 diabetes dendritic cells and monocytes

Mollah, Zia U.A., Pai, Saparna, Craig Moore, O'Sullivan, Brendan J., Harrison, Matthew J., Peng, Judy, Phillips, Karen, Prins, Johannes B., Cardinal, John and Thomas, Ranjeny (2008). Abnormal NF-kappa B function characterizes human type 1 diabetes dendritic cells and monocytes. Journal of Immunology, 180 (5), 3166-3175. doi: 10.4049/jimmunol.180.5.3166

Abnormal NF-kappa B function characterizes human type 1 diabetes dendritic cells and monocytes

2008

Journal Article

Steady-state dendritic cells expressing cognate antgen terminate memory CD8+ T-cell responses

Kenna, Tony J., Thomas, Ranjeny and Steptoe, Raymond J. (2008). Steady-state dendritic cells expressing cognate antgen terminate memory CD8+ T-cell responses. Blood, 111 (4), 2091-2100. doi: 10.1182/blood-2007-07-103200

Steady-state dendritic cells expressing cognate antgen terminate memory CD8+ T-cell responses

2008

Book Chapter

Dendritic Cells

Pai, Saparna and Thomas, Ranjeny (2008). Dendritic Cells. Rheumatoid Arthritis. (pp. 116-123) Elsevier. doi: 10.1016/B978-032305475-1.50021-5

Dendritic Cells

2007

Journal Article

Atherosclerotic disease is increased in recent onset rheumatoid arthritis: a critical role for inflammation

Hannawi, Suad, Haluska, Brian, Marwick, Thomas H. and Thomas, Ranjeny (2007). Atherosclerotic disease is increased in recent onset rheumatoid arthritis: a critical role for inflammation. Arthritis Research and Therapy, 9 (6) R116, R116.1-R116.9. doi: 10.1186/ar2323

Atherosclerotic disease is increased in recent onset rheumatoid arthritis: a critical role for inflammation

2007

Journal Article

Cells of the synovium in rheumatoid arthritis: dendritic cells

Lutzky, Viviana, Suad Hannawi, Suad and Thomas, Ranjeny (2007). Cells of the synovium in rheumatoid arthritis: dendritic cells. Arthritis Research and Therapy, 9 (4) 219, 219-230. doi: 10.1186/ar2200

Cells of the synovium in rheumatoid arthritis: dendritic cells

2007

Journal Article

Plasmodium strain determines dendritic cell function essential for survival from malaria

Wykes, Michelle N., Liu, Xue Q., Beattie, Lynette, Stanisic, Danielle I., Stacey, Katryn J., Smyth, Mark J., Thomas, Ranjeny and Good, Michael F. (2007). Plasmodium strain determines dendritic cell function essential for survival from malaria. PLoS Pathogens, 3 (7), e96-0904-e96-0912. doi: 10.1371/journal.ppat.0030096

Plasmodium strain determines dendritic cell function essential for survival from malaria