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2008

Journal Article

Molecular engineering of conotoxins: The importance of loop size to alpha-conotoxin structure and function

Jin, Ai-Hua, Daly, N. L., Nevin, S. T., Wang, C. I. A., Dutertre, S., Lewis, R. J., Adams, D. J., Craik, D. J. and Alewood, P. F. (2008). Molecular engineering of conotoxins: The importance of loop size to alpha-conotoxin structure and function. Journal of Medicinal Chemistry, 51 (18), 5575-5584. doi: 10.1021/jm800278k

Molecular engineering of conotoxins: The importance of loop size to alpha-conotoxin structure and function

2008

Journal Article

Oxidative Folding of cyclic cystine knot proteins

Cemazar, M., Gruber, C. W. and Craik, D. J. (2008). Oxidative Folding of cyclic cystine knot proteins. Antioxidants and Redox Signaling, 10 (1), 103-111. doi: 10.1089/ars.2007.1849

Oxidative Folding of cyclic cystine knot proteins

2008

Journal Article

Quantitative analysis of backbone-cyclised peptides in plants

Saska, I., Colgrave, M. L., Jones, A., Anderson, M. A. and Craik, D. J. (2008). Quantitative analysis of backbone-cyclised peptides in plants. Journal of Chromatography B, 872 (1-2), 107-114. doi: 10.1016/j.jchromb.2008.07.023

Quantitative analysis of backbone-cyclised peptides in plants

2008

Journal Article

Altered metabolism of growth hormone receptor mutant mice: a combined NMR metabonomics and microarray study

Schirra, Horst Joachim, Anderson, Cameron G., Wilson, William J., Kerr, Linda, Craik, David J., Waters, Michael J. and Lichanska, Agnieszka M. (2008). Altered metabolism of growth hormone receptor mutant mice: a combined NMR metabonomics and microarray study. PLoS One, 3 (7) e2764, e2764-1-e2764-15. doi: 10.1371/journal.pone.0002764

Altered metabolism of growth hormone receptor mutant mice: a combined NMR metabonomics and microarray study

2008

Journal Article

Protease-catalysed protein splicing: a new post-translational modification?

Ivana Saska and Craik, David J. (2008). Protease-catalysed protein splicing: a new post-translational modification?. Trends In Biochemical Sciences, 33 (8), 363-368. doi: 10.1016/j.tibs.2008.04.016

Protease-catalysed protein splicing: a new post-translational modification?

2008

Journal Article

The structure of a two-disulfide intermediate assists in elucidating the oxidative folding pathway of a cyclic cystine knot protein

Cemazar, M., Joshi, A., Daly, N. L., Mark, A. E. and Craik, D. J. (2008). The structure of a two-disulfide intermediate assists in elucidating the oxidative folding pathway of a cyclic cystine knot protein. Structure, 16 (6), 842-851. doi: 10.1016/j.str.2008.02.023

The structure of a two-disulfide intermediate assists in elucidating the oxidative folding pathway of a cyclic cystine knot protein

2008

Journal Article

Backbone cyclised peptides from plants show molluscicidal activity against the rice pest pomacaea canaliculata (golden apple snail)

Plan, Manuel R. Rey, Saska, Ivana, Cagauan, Arsenia and Craik, David J. (2008). Backbone cyclised peptides from plants show molluscicidal activity against the rice pest pomacaea canaliculata (golden apple snail). Journal of Agricultural and Food Chemistry, 56 (13), 5237-5241. doi: 10.1021/jf800302f

Backbone cyclised peptides from plants show molluscicidal activity against the rice pest pomacaea canaliculata (golden apple snail)

2008

Journal Article

Engineering stablized vascular endothelial growth factor-A antagonists: synthesis, structural characterization and bioactivity of grafted analogues of cyclotides

Gunasekera, Sunithi, Foley, Fiona M., Clark, Richard J., Sando, Lillian, Fabri, Louis J., Craik, David J. and Daly, Norelle L. (2008). Engineering stablized vascular endothelial growth factor-A antagonists: synthesis, structural characterization and bioactivity of grafted analogues of cyclotides. Journal of Medicinal Chemistry, 51 (24), 7697-7704. doi: 10.1021/jm800704e

Engineering stablized vascular endothelial growth factor-A antagonists: synthesis, structural characterization and bioactivity of grafted analogues of cyclotides

2008

Journal Article

Tyrosine-rich conopeptides affect voltage-gated K+ channels

Imperial, Julita S., Chen, Ping, Sporning, Annett, Terlau, Heinrich, Daly, Norelle L., Craik, David J., Alewood, Paul F. and Olivera, Baldormero M. (2008). Tyrosine-rich conopeptides affect voltage-gated K+ channels. The journal of biological chemistry, 283 (34), 23026-23032. doi: 10.1074/jbc.M800084200

Tyrosine-rich conopeptides affect voltage-gated K+ channels

2008

Journal Article

Structural refinement of insecticidal plant proteinase inhibitors from Nicotiana alata

Schirra, H. J., Anderson, M and Craik, D. J. (2008). Structural refinement of insecticidal plant proteinase inhibitors from Nicotiana alata. Protein and Peptide Letters, 15 (9), 903-909. doi: 10.2174/092986608785849326

Structural refinement of insecticidal plant proteinase inhibitors from Nicotiana alata

2008

Journal Article

Binding mode of alpha-conotoxins to an acetylcholine binding protein determined by saturation transfer difference NMR

Westermann, Jan, Clark, Richard J. and Craik, David J. (2008). Binding mode of alpha-conotoxins to an acetylcholine binding protein determined by saturation transfer difference NMR. Protein And Peptide Letters, 15 (9), 910-914. doi: 10.2174/092986608785849335

Binding mode of alpha-conotoxins to an acetylcholine binding protein determined by saturation transfer difference NMR

2008

Journal Article

15N cyclotides by whole plant labeling

Mylne, Joshua S. and Craik, David J. (2008). 15N cyclotides by whole plant labeling. Peptide Science, 90 (4), 575-580. doi: 10.1002/bip.21012

15N cyclotides by whole plant labeling

2008

Journal Article

Cyclotides: Natural, Circular Plant Peptides that possess significant activity against Gastrointestinal nematode parasites of sheep

Colgrave, M. L., Kotze, A. C., Huang, Y., O'Grady, J., Simonsen, S. M. and Craik, D. J. (2008). Cyclotides: Natural, Circular Plant Peptides that possess significant activity against Gastrointestinal nematode parasites of sheep. Biochemistry, 47 (20), 5581-5589. doi: 10.1021/bi800223y

Cyclotides: Natural, Circular Plant Peptides that possess significant activity against Gastrointestinal nematode parasites of sheep

2008

Journal Article

Alanine Scanning mutagenesis of the prototypic cyclotide reveals a cluster of residues essential for bioactivity

Simonsen, S. M., Sando, L., Rosengren, K. J., Wang, C. K., Colgrave, M. L., Daly, N. L. and Craik, D. J. (2008). Alanine Scanning mutagenesis of the prototypic cyclotide reveals a cluster of residues essential for bioactivity. Journal of Biological Chemistry, 283 (15), 9805-9813. doi: 10.1074/jbc.M709303200

Alanine Scanning mutagenesis of the prototypic cyclotide reveals a cluster of residues essential for bioactivity

2008

Journal Article

Structure and folding of disulfide-rich miniproteins: insights from molecular dynamics simulations and MM-PBSA free energy calculations

Combelles, C., Gracy, J., Heitz, A., Craik, D. J. and Chiche, L. (2008). Structure and folding of disulfide-rich miniproteins: insights from molecular dynamics simulations and MM-PBSA free energy calculations. Proteins, 73 (1), 87-103. doi: 10.1002/prot.22054

Structure and folding of disulfide-rich miniproteins: insights from molecular dynamics simulations and MM-PBSA free energy calculations

2008

Journal Article

Conopressin-T from Conus tulipa reveals an antagonist switch in vasopressin-like peptide

Dutertre, Sébastien, Croker, Daniel, Daly, Norelle L., Andersson, Åsa, Muttenthaler, Markus, Lumsden, Natalie G., Craik, David J., Alewood, Paul F., Guillon, Gilles and Lewis, Richard J. (2008). Conopressin-T from Conus tulipa reveals an antagonist switch in vasopressin-like peptide. Journal of Biological Chemistry, 283 (11), 7100-7108. doi: 10.1074/jbc.M706477200

Conopressin-T from Conus tulipa reveals an antagonist switch in vasopressin-like peptide

2008

Journal Article

The three-dimensional structure of the analgesic alpha-conotoxin, RgIA

Clark, Richard J., Daly, Norelle L., Halai, Reena, Nevin, Simon T., Adams, David J. and Craik, David J. (2008). The three-dimensional structure of the analgesic alpha-conotoxin, RgIA. FEBS Letters, 582 (5), 597-602. doi: 10.1016/j.febslet.2008.01.027

The three-dimensional structure of the analgesic alpha-conotoxin, RgIA

2008

Journal Article

The alpine violet, Viola biflora, is a rich source of cyclotides with potent cytotoxicity

Herrman, Anders, Burman, Robert, Mylne, Joshua S., Karlsson, Gustav, Gullbo, Joachim, Craik, David J., Clark, Richard J. and Goransson, Ulf (2008). The alpine violet, Viola biflora, is a rich source of cyclotides with potent cytotoxicity. Phytochemistry, 69 (4), 939-952. doi: 10.1016/j.phytochem.2007.10.023

The alpine violet, Viola biflora, is a rich source of cyclotides with potent cytotoxicity

2008

Journal Article

ConoServer, a database for conopeptide sequences and structures

Kaas, Quentin, Westermann, Jan, Halai, Reena, Wang, Conan and Craik, David J. (2008). ConoServer, a database for conopeptide sequences and structures. Bioinformatics, 24 (3), 445-446. doi: 10.1093/bioinformatics/btm596

ConoServer, a database for conopeptide sequences and structures

2008

Journal Article

Plant cyclotides disrupt epithelial cells in the midgut of lepidopteran larvae

Barbeta, Barbara L., Marshall, Alan T., Gillon, Amanda D., Craik, David J. and Anderson, Marilyn A. (2008). Plant cyclotides disrupt epithelial cells in the midgut of lepidopteran larvae. Proceedings of the National Acadamy of Sciences of the United State of America, 105 (4), 1221-1225. doi: 10.1073/pnas.0710338104

Plant cyclotides disrupt epithelial cells in the midgut of lepidopteran larvae