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2005

Journal Article

Increased potency of a novel complement factor 5a receptor antagonist in a rat model of inflammatory bowel disease

Woodruff, T. M., Pollitt, S., Proctor, L. M., Stocks, S. Z., Manthey, H. D., Williams, H. M., Mahadevan, I. B., Shiels, I. A. and Taylor, S. M. (2005). Increased potency of a novel complement factor 5a receptor antagonist in a rat model of inflammatory bowel disease. Journal of Pharmacology And Experimental Therapeutics, 314 (2), 811-817. doi: 10.1124/jpet.105.086835

Increased potency of a novel complement factor 5a receptor antagonist in a rat model of inflammatory bowel disease

2004

Journal Article

Protective effect of a human C5a receptor antagonist against hepatic ischaemia-reperfusion injury in rats

Arumugam, Thiruma V., Woodruff, Trent M., Stocks, Shelli Z., Proctor, Lavinia M., Pollitt, Sandra, Shiels, Ian A., Reid, Robert C., Fairlie, David P. and Taylor, Stephen M. (2004). Protective effect of a human C5a receptor antagonist against hepatic ischaemia-reperfusion injury in rats. Journal of Hepatology, 40 (6), 934-941. doi: 10.1016/S0168-8278(04)00066-2

Protective effect of a human C5a receptor antagonist against hepatic ischaemia-reperfusion injury in rats

2004

Journal Article

Protective effect of a human C5a receptor antagonist against hepatic ischaemia-reperfusion injury in rats

Arumugam, Thiruma V., Woodruff, Trent M., Stocks, Shelli Z., Proctor, Lavinia M., Pollitt, Sandra, Shiels, Ian A., Reid, Robert C., Fairlie, David P., Taylor, Stephen M. and M. Colombo (2004). Protective effect of a human C5a receptor antagonist against hepatic ischaemia-reperfusion injury in rats. Journal of Hepatology, 40 (6), 934-941. doi: 10.1016/j.jhep.2004.02.017

Protective effect of a human C5a receptor antagonist against hepatic ischaemia-reperfusion injury in rats

2004

Journal Article

The role of the complement system in ischemia-reperfusion injury

Arumugam, Thiruma V., Shiels, Ian A., Woodruff, Trent M., Granger, D. Neil and Taylor, Stephen M. (2004). The role of the complement system in ischemia-reperfusion injury. Shock, 21 (5), 401-409. doi: 10.1097/01.shk.0000121227.73012.86

The role of the complement system in ischemia-reperfusion injury

2004

Journal Article

Protective effects of a potent C5a receptor antagonist on experimental acute limb ishemia-reperfusion in rats

Woodruff, Trent M., Arumugam, Thiruma V., Shiels, Ian A., Reid, Robert C., Fairlie, David P. and Taylor, Stephen M. (2004). Protective effects of a potent C5a receptor antagonist on experimental acute limb ishemia-reperfusion in rats. Journal of Surgical Research, 116 (1), 81-90. doi: 10.1016/j.jss.2003.04.001

Protective effects of a potent C5a receptor antagonist on experimental acute limb ishemia-reperfusion in rats

2004

Journal Article

Potent cyclic antagonists of the complement C5a receptor on human polymorphonulcear leukocytes. Relationships between structures and activity

March, Darren R., Proctor, Lavinia M., Stoermer, Martin J., Sbaglia, Robert, Abbenante, Giovanni, Reid, Robert C., Woodruff, Trent M., Wadi, Khemar, Paczkowski, Natalii, Tyndall, Joel D. A., Taylor, Stephen M. and Fairlie, David P. (2004). Potent cyclic antagonists of the complement C5a receptor on human polymorphonulcear leukocytes. Relationships between structures and activity. Molecular Pharmacology, 65 (4), 868-879. doi: 10.1124/mol.65.4.868

Potent cyclic antagonists of the complement C5a receptor on human polymorphonulcear leukocytes. Relationships between structures and activity

2003

Journal Article

A potent human C5a receptor antagonist protects against disease pathology in a rat model of inflammatory bowel disease

Woodruff, Trent M., Arumugam, Thiruma V., Shiels, Ian A., Reid, Robert C., Fairlie, David P. and Taylor, Stephen M. (2003). A potent human C5a receptor antagonist protects against disease pathology in a rat model of inflammatory bowel disease. Journal of Immunology, 171 (10), 5514-5520. doi: 10.4049/jimmunol.171.10.5514

A potent human C5a receptor antagonist protects against disease pathology in a rat model of inflammatory bowel disease

2002

Journal Article

Antiarthritic activity of an orally active C5a receptor antagonist against antigen-induced monarticular arthritis in the rat

Woodruff, Trent M., Strachan, Anna J., Dryburgh, Nathan, Shiels, Ian A., Reid, Robert C., Fairlie, David P. and Taylor, Stephen M. (2002). Antiarthritic activity of an orally active C5a receptor antagonist against antigen-induced monarticular arthritis in the rat. Arthritis and Rheumatism, 46 (9), 2476-2485. doi: 10.1002/art.10449

Antiarthritic activity of an orally active C5a receptor antagonist against antigen-induced monarticular arthritis in the rat

2002

Journal Article

Evaluation of VIDAS ® Immuno-concentration Salmonella/VIDAS Salmonella immunoassay method for detection of Salmonella in selected foods: Collaborative study

Lepper, Wendy A., Schultz, Ann M., Curiale, Michael S., Johnson, Ronald L., Agin, J., Campbell, S., Carver, C., Cherney, D., Copeland, F., Ekholm, D., Eklund, C., Gangar, V., Gardner, F., Herbst, K., High, E., Kallstrom, C., Lee, J., Lucas, J., Lyons, W., Maselli, M., Miele, M., Muehlenkamp, E., Muzzy, T., Nutsch, A., Parra, G., Post, L., Ryser, E., Schultz, A., Scorah, C. ... Woodruff, T. (2002). Evaluation of VIDAS ® Immuno-concentration Salmonella/VIDAS Salmonella immunoassay method for detection of Salmonella in selected foods: Collaborative study. Journal of AOAC International, 85 (3), 609-625.

Evaluation of VIDAS ® Immuno-concentration Salmonella/VIDAS Salmonella immunoassay method for detection of Salmonella in selected foods: Collaborative study

2002

Journal Article

Protective effect of a new C5a receptor antagonist against Ischemia-reperfusion injury in the rat small intestine

Arumugam, Thiruma V., Shiels, Ian A., Woodruff, Trent M., Reid, Robert C., Fairlie, David P. and Taylor, Stephen M. (2002). Protective effect of a new C5a receptor antagonist against Ischemia-reperfusion injury in the rat small intestine. Journal of Surgical Research, 103 (2), 260-267. doi: 10.1006/jsre.2002.6369

Protective effect of a new C5a receptor antagonist against Ischemia-reperfusion injury in the rat small intestine

2002

Journal Article

Evaluation of VIDAS®Immuno-concentration Salmonella assay plus selective plate method (Hektoen enteric, bismuth sulfite, Salmonella identification) for detection of Salmonella in selected foods: Collaborative study

Lepper, Wendy A., Schultz, Ann M., Curiale, Michael S., Johnson, Ronald L., Agin, J., Campbell, S., Carver, C., Cherney, D., Copeland, F., Ekholm, D., Eklund, C., Gangar, V., Gardner, F., Herbst, K., High, E., Kallstrom, C., Lee, J., Lucas, J., Lyons, W., Maselli, M., Miele, M., Muehlenkamp, E., Muzzy, T., Nutsch, A., Parra, G., Post, L., Ryser, E., Schultz, A., Scorah, C. ... Woodruff, T. (2002). Evaluation of VIDAS®Immuno-concentration Salmonella assay plus selective plate method (Hektoen enteric, bismuth sulfite, Salmonella identification) for detection of Salmonella in selected foods: Collaborative study. Journal of AOAC International, 85 (3), 576-592. doi: 10.1093/jaoac/85.3.576

Evaluation of VIDAS®Immuno-concentration Salmonella assay plus selective plate method (Hektoen enteric, bismuth sulfite, Salmonella identification) for detection of Salmonella in selected foods: Collaborative study

2002

Journal Article

Salmonella in selected foods by VIDAS® Immuno-concentration Salmonella plus selective plate method (Hektoen enteric, xylose lysine desoxycholate, bismuth sulfite): Collaborative study

Lepper, Wendy A., Schultz, Ann M., Curiale, Michael S., Johnson, Ronald L., Agin, J., Campbell, S., Carver, C., Cherney, D., Copeland, F., Ekholm, D., Eklund, C., Gangar, V., Gardner, F., Herbst, K., High, E., Kallstrom, C., Lee, J., Lucas, J., Lyons, W., Maselli, M., Miele, M., Muehlenkamp, E., Muzzy, T., Nutsch, A., Parra, G., Post, L., Ryser, E., Schultz, A., Scorah, C. ... Woodruff, T. (2002). Salmonella in selected foods by VIDAS® Immuno-concentration Salmonella plus selective plate method (Hektoen enteric, xylose lysine desoxycholate, bismuth sulfite): Collaborative study. Journal of AOAC International, 85 (3), 593-608. doi: 10.1093/jaoac/85.3.593

Salmonella in selected foods by VIDAS® Immuno-concentration Salmonella plus selective plate method (Hektoen enteric, xylose lysine desoxycholate, bismuth sulfite): Collaborative study

2001

Journal Article

Species dependence for binding of small molecule agonist and antagonists to the C5a receptor on polymorphonuclear leukocytes

Woodruff, Trent M., Strachan, Anna J., Sanderson, Sam D., Monk, Peter N., Wong, Allan K., Fairlie, David P. and Taylor, Stephen M. (2001). Species dependence for binding of small molecule agonist and antagonists to the C5a receptor on polymorphonuclear leukocytes. Inflammation, 25 (3), 171-177. doi: 10.1023/A:1011036414353

Species dependence for binding of small molecule agonist and antagonists to the C5a receptor on polymorphonuclear leukocytes

2001

Journal Article

Modulation of ligand selectivity by mutation of the first extracellular loop of the human C5a receptor

Cain, S. A., Woodruff, T. M., Taylor, S. M., Fairlie, D. P., Sanderson, S. D. and Monk, P. N. (2001). Modulation of ligand selectivity by mutation of the first extracellular loop of the human C5a receptor. Biochemical Pharmacology, 61 (12), 1571-1579. doi: 10.1016/S0006-2952(01)00608-6

Modulation of ligand selectivity by mutation of the first extracellular loop of the human C5a receptor

2000

Journal Article

A new small molecule C5a receptor antagonist inhibits the reverse- passive Arthus reaction and endotoxic shock in rats

Strachan, Anna J., Woodruff, Trent M., Haaima, Gerald, Fairlie, David P. and Taylor, Stephen M. (2000). A new small molecule C5a receptor antagonist inhibits the reverse- passive Arthus reaction and endotoxic shock in rats. Journal of Immunology, 164 (12), 6560-6565. doi: 10.4049/jimmunol.164.12.6560

A new small molecule C5a receptor antagonist inhibits the reverse- passive Arthus reaction and endotoxic shock in rats

2000

Journal Article

A new small molecule C5a receptor antagonist inhibits the reverse-passive arthus reaction and endotoxic shock in rats

Strachan, A. J., Woodruff, T.M., Haaima, G., Fairlie, D. P. and Taylor, S. M. (2000). A new small molecule C5a receptor antagonist inhibits the reverse-passive arthus reaction and endotoxic shock in rats. Journal of Immunology, 164 (4), 6560-6565.

A new small molecule C5a receptor antagonist inhibits the reverse-passive arthus reaction and endotoxic shock in rats