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2013 Journal Article Complement factor C5a as mast cell activator mediates vascular remodelling in vein graft diseasede Vries, Margreet R., Wezel, Anouk, Schepers, Abbey, van Santbrink, Peter J., Woodruff, Trent M., Niessen, Hans W. M., Hamming, Jaap F., Kuiper, Johan, Bot, Ilze and Quax, Paul H. A. (2013). Complement factor C5a as mast cell activator mediates vascular remodelling in vein graft disease. Cardiovascular Research, 97 (2), 311-320. doi: 10.1093/cvr/cvs312 |
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2013 Journal Article Neutrophils-A key component of ischemia-reperfusion injurySchofield, Zoe Victoria, Woodruff, Trent Martin, Halai, Reena, Wu, Mike Chia-Lun and Cooper, Matthew Allister (2013). Neutrophils-A key component of ischemia-reperfusion injury. Shock, 40 (6), 463-470. doi: 10.1097/SHK.0000000000000044 |
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2013 Journal Article The C5a receptor antagonist PMX205 ameliorates experimentally induced colitis associated with increased IL-4 and IL-10Jain, U., Woodruff, T. M. and Stadnyk, A. W. (2013). The C5a receptor antagonist PMX205 ameliorates experimentally induced colitis associated with increased IL-4 and IL-10. British Journal of Pharmacology, 168 (2), 488-501. doi: 10.1111/j.1476-5381.2012.02183.x |
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2013 Journal Article Complement in pregnancy: a delicate balanceDenny, Kerina J., Woodruff, Trent M., Taylor, Stephen M. and Callaway, Leonie K. (2013). Complement in pregnancy: a delicate balance. American Journal of Reproductive Immunology, 69 (1), 3-11. doi: 10.1111/aji.12000 |
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2013 Journal Article Neural tube defects, folate, and immune modulationDenny, Kerina J., Jeanes, Angela, Fathe, Kristin, Finnell, Richard H., Taylor, Stephen M. and Woodruff, Trent M. (2013). Neural tube defects, folate, and immune modulation. Birth Defects Research Part A - Clinical and Molecular Teratology, 97 (9), 602-609. doi: 10.1002/bdra.23177 |
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2012 Journal Article Eph/Ephrin signaling in injury and inflammationCoulthard, Mark G., Morgan, Michael, Woodruff, Trent M., Arumugam, Thiruma V., Taylor, Stephen M., Carpenter, Todd C., Martin Lackmann, and Boyd, Andrew W. (2012). Eph/Ephrin signaling in injury and inflammation. American Journal of Pathology, 181 (5), 1493-1503. doi: 10.1016/j.ajpath.2012.06.043 |
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2012 Journal Article Generation of complement component C5a by ischemic neurons promotes neuronal apoptosisPavlovski, Dale, Thundyil, John, Monk, Peter N., Wetsel, Rick A., Taylor, Stephen M. and Woodruff, Trent M. (2012). Generation of complement component C5a by ischemic neurons promotes neuronal apoptosis. The FASEB Journal, 26 (9), 3680-3690. doi: 10.1096/fj.11-202382 |
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2012 Journal Article Complement activation in the injured central nervous system: Another dual-edged sword?Brennan, Faith H., Anderson, Aileen J., Taylor, Stephen M., Woodruff, Trent M. and Ruitenberg, Marc J. (2012). Complement activation in the injured central nervous system: Another dual-edged sword?. Journal of Neuroinflammation, 9 (1) 137, 137. doi: 10.1186/1742-2094-9-137 |
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2012 Journal Article Complement C5a regulates prolabor mediators in human placentaLappas, Martha, Woodruff, Trent M., Taylor, Stephen M. and Permezel, Michael (2012). Complement C5a regulates prolabor mediators in human placenta. Biology of Reproduction, 86 (6) 190, 190.1-190.9. doi: 10.1095/biolreprod.111.098475 |
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2012 Journal Article De novo peptide design with C3a receptor agonist and antagonist activities: Theoretical predictions and experimental validationBellows-Peterson, Meghan L., Fung, Ho Ki, Floudas, Christodoulos A., Kieslich, Chris A., Zhang, Li, Morikis, Dimitrios, Wareham, Kathryn J., Monk, Peter N., Hawksworth, Owen A. and Woodruff, Trent M. (2012). De novo peptide design with C3a receptor agonist and antagonist activities: Theoretical predictions and experimental validation. Journal of Medicinal Chemistry, 55 (9), 4159-4168. doi: 10.1021/jm201609k |
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2011 Journal Article Inhibition of inflammation and fibrosis by a complement C5a receptor antagonist in DOCA-salt hypertensive ratsIyer, Abishek, Woodruff, Trent M., Wu, Mike C. L., Stylianou, Con, Reid, Robert C., Fairlie, David P., Taylor, Stephen M. and Brown, Lindsay (2011). Inhibition of inflammation and fibrosis by a complement C5a receptor antagonist in DOCA-salt hypertensive rats. Journal of Cardiovascular Pharmacology, 58 (5), 479-486. doi: 10.1097/FJC.0b013e31822a7a09 |
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2011 Journal Article Inhibiting the C5-C5a receptor axisWoodruff, Trent M., Nandakumar, Kutty S. and Tedesco, Francesco (2011). Inhibiting the C5-C5a receptor axis. Molecular Immunology, 48 (14), 1631-1642. doi: 10.1016/j.molimm.2011.04.014 |
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2011 Journal Article Complement C5a inhibition reduces atherosclerosis in ApoE(-/-) miceManthey, Helga D., Thomas, Anita C., Shiels, Ian A., Zernecke, Alma, Woodruff, Trent M., Rolfe, Barbara and Taylor, Stephen M. (2011). Complement C5a inhibition reduces atherosclerosis in ApoE(-/-) mice. FASEB Journal, 25 (7), 2447-2455. doi: 10.1096/fj.10-174284 |
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2011 Journal Article Oral treatment with complement factor C5a receptor (CD88) antagonists inhibits experimental periodontitis in ratsBreivik, T., Gundersen, Y., Gjermo, P., Taylor, S. M., Woodruff, T. M. and Opstad, P. K. (2011). Oral treatment with complement factor C5a receptor (CD88) antagonists inhibits experimental periodontitis in rats. Journal of Periodontal Research, 46 (6), 643-647. doi: 10.1111/j.1600-0765.2011.01383.x |
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2011 Journal Article Pathophysiology, treatment, and animal and cellular models of human ischemic strokeWoodruff, Trent M., Thundyil, John, Tang, Sung Chun, Sobey, Christopher G., Taylor, Stephen M. and Arumugam, Thiruma V. (2011). Pathophysiology, treatment, and animal and cellular models of human ischemic stroke. Molecular Neurodegeneration, 6 (1) 11, 1-19. doi: 10.1186/1750-1326-6-11 |
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2011 Journal Article Increased expression of C5a receptor (CD88) mRNA in canine mammary tumorsHezmee, Mohd Noor Mohd, Kyaw-Tanner, Myat, Lee, Jia Yu Peppermint, Shiels, Ian A., Rolfe, Barbara, Woodruff, Trent and Mills, Paul C. (2011). Increased expression of C5a receptor (CD88) mRNA in canine mammary tumors. Veterinary Immunology and Immunopathology, 139 (1), 50-56. doi: 10.1016/j.vetimm.2010.08.005 |
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2011 Journal Article Comparative efficacy of a secretory phospholipase A(2) inhibitor with conventional anti-inflammatory agents in a rat model of antigen-induced arthritisCoulthard, Liam G., Costello, Jaclyn, Robinson, Brent, Shiels, Ian A., Taylor, Stephen M. and Woodruff, Ttrent M. (2011). Comparative efficacy of a secretory phospholipase A(2) inhibitor with conventional anti-inflammatory agents in a rat model of antigen-induced arthritis. Arthritis Research & Therapy, 13 (2) R42, R42-1-R42-10. doi: 10.1186/ar3278 |
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2010 Journal Article Evidence that adiponectin receptor 1 activation exacerbates ischemic neuronal deathThundyil, John, Tang, Sung-Chun, Okun, Eitan, Shah, Kausik, Karamyan, Vardan T., Li , Yu-I, Woodruff, Trent M., Taylor, Stephen M., Jo, Dong-Gyu, Mattson, Mark P and Arumugam, Thiruma V. (2010). Evidence that adiponectin receptor 1 activation exacerbates ischemic neuronal death. Experimental and Translational Stroke Medicine, 2 (1) 15, 15-1-15-8. doi: 10.1186/2040-7378-2-15 |
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2010 Journal Article The role of the ribosomal protein S19 C-terminus in Gi protein-dependent alternative activation of p38 MAP kinase via the C5a receptor in HMC-1 cellsNishiura, Hiroshi, Tokita, Kazutaka, Li, Ying, Harada, Koichi, Woodruff, Trent W., Taylor, Stephen M., Nsiama, Tienabe K., Nishino, Norikazu and Yamamoto, Tetsuro (2010). The role of the ribosomal protein S19 C-terminus in Gi protein-dependent alternative activation of p38 MAP kinase via the C5a receptor in HMC-1 cells. Apoptosis, 15 (8), 966-981. doi: 10.1007/s10495-010-0511-y |
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2010 Journal Article The role of the complement system and the activation fragment C5a in the central nervous systemWoodruff, T. M., Ager, R. R., Tenner, A. J., Noakes, P. G. and Taylor, S. M. (2010). The role of the complement system and the activation fragment C5a in the central nervous system. Neuromolecular Medecine, 12 (2), 179-192. doi: 10.1007/s12017-009-8085-y |
