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2010 Journal Article Microglial C5aR (CD88) expression correlates with amyloid-β deposition in murine models of Alzheimer's diseaseAger, Rahasson R., Fonseca, Maira I., Chu, Shu-Hui, Sanderson, Sam D., Taylor, Stephen M., Woodruff, Trent M. and Tenner, Andrea J. (2010). Microglial C5aR (CD88) expression correlates with amyloid-β deposition in murine models of Alzheimer's disease. Journal of Neurochemistry, 113 (2), 389-401. doi: 10.1111/j.1471-4159.2010.06595.x |
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2010 Journal Article Quantitative analysis of cellular inflammation after traumatic spinal cord injury: Evidence for a multiphasic inflammatory response in the acute to chronic environmentBeck, Kevin D., Nguyen, Hal X., Galvan, Manuel D., Salazar, Desireé L., Woodruff, Trent M. and Anderson, Aileen J. (2010). Quantitative analysis of cellular inflammation after traumatic spinal cord injury: Evidence for a multiphasic inflammatory response in the acute to chronic environment. Brain, 133 (2), 433-447. doi: 10.1093/brain/awp322 |
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2009 Journal Article Dendritic cell function in allostimulation is modulated by C5aR signalingPeng, Qi, Li, Ke, Wang, Naiyin, Li, Qijun, Asgari, Elham, Lu, Bao, Woodruff, Trent M., Sacks, Steven H. and Zhou, Wuding (2009). Dendritic cell function in allostimulation is modulated by C5aR signaling. Journal of Immunology, 183 (10), 6058-6068. doi: 10.4049/jimmunol.0804186 |
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2009 Journal Article Complement component 5a (C5a)Manthey, Helga D., Woodruff, Trent M., Taylor, Stephen M. and Monk, Peter N. (2009). Complement component 5a (C5a). International Journal of Biochemistry and Cell Biology, 41 (11), 2114-2117. doi: 10.1016/j.biocel.2009.04.005 |
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2009 Journal Article Pivotal role for beta-1 integrin in neurovascular remodelling after ischemic strokeLathia, Justin D., Chigurupati, Srinivasulu, Thundyil, John, Selvaraj, Pradeep K., Mughal, Mohamed R., Woodruff, Trent M., Chan, Sic L., Karamyan, Vardan T., Mattson, Mark P. and Arumugam, Thiruma V. (2009). Pivotal role for beta-1 integrin in neurovascular remodelling after ischemic stroke. Experimental Neurology, 221 (1), 107-114. doi: 10.1016/j.expneurol.2009.10.007 |
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2009 Journal Article Treatment with a C5aR antagonist decreases pathology and enhances behavioral performance in murine models of Alzheimer's diseaseFonseca, Maria I., Ager, Rahasson R., Chu, Shu-Hui, Yazan, Ozkan, Sanderson, Sam D., LaFerla, Frank M., Taylor, Stephen M., Woodruff, Trent M. and Tenner, Andrea J. (2009). Treatment with a C5aR antagonist decreases pathology and enhances behavioral performance in murine models of Alzheimer's disease. Journal of Immunology, 183 (2), 1375-1383. doi: 10.4049/jimmunol.0901005 |
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2009 Journal Article Toll-like receptors in ischemia-reperfusion injuryArumugam, Thiruma V., Okun, Eitan, Tang, Sung-Chun, Thundyil, John, Taylor, Stephen M. and Woodruff, Trent M. (2009). Toll-like receptors in ischemia-reperfusion injury. Shock, 32 (1), 4-16. doi: 10.1097/SHK.0b013e318193e333 |
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2009 Journal Article Complement factors C3a and C5a have distinct hemodynamic effects in the ratProctor, Lavinia M., Moore, Tyson A., Monk, Peter N., Sanderson, Sam D., Taylor, Stephen M. and Woodruff, Trent M. (2009). Complement factors C3a and C5a have distinct hemodynamic effects in the rat. International Immunopharmacology, 9 (6), 800-806. doi: 10.1016/j.intimp.2009.03.002 |
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2009 Journal Article Neuroprotection in stroke by complement inhibition and immunoglobulin therapyArumugam, T V, Woodruff, T M, Lathia, J D, Selvaraj, P K, Mattson, M P and Taylor, S M (2009). Neuroprotection in stroke by complement inhibition and immunoglobulin therapy. Neuroscience, 158 (3), 1074-1089. doi: 10.1016/j.neuroscience.2008.07.015 |
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2009 Journal Article The C5a anaphylatoxin receptor CD88 is expressed in presynaptic terminals of hippocampal mossy fibresCrane, James W., Baiquni, Gilang P., Sullivan, Robert K. P., Lee, John D, Sah, Pankaj, Taylor, Stephen M, Noakes, Peter G. and Woodruff, Trent (2009). The C5a anaphylatoxin receptor CD88 is expressed in presynaptic terminals of hippocampal mossy fibres. Journal of Neuroinflammation, 6 (34) 34, 34.1-34.10. doi: 10.1186/1742-2094-6-34 |
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2008 Journal Article The Complement Factor C5a Contributes to Pathology in a Rat Model of Amyotrophic Lateral SclerosisWoodruff, Trent M., Costantini, Kerina J., Crane, James W., Atkin, Julie D., Monk, Peter N., Taylor, Stephen M. and Noakes, Peter G. (2008). The Complement Factor C5a Contributes to Pathology in a Rat Model of Amyotrophic Lateral Sclerosis. Journal of Immunology, 181 (12), 8727-8734. doi: 10.4049/jimmunol.181.12.8727 |
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2008 Journal Article Role of complement in motor neuron disease: animal models and therapeutic potential of complement inhibitorsWoodruff, Trent M., Costantini, Kerina J., Taylor, Steve M. and Noakes, Peter G. (2008). Role of complement in motor neuron disease: animal models and therapeutic potential of complement inhibitors. Advances in Experimental Medicine and Biology, 632, 143-158. |
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2008 Journal Article Pharmacokinetics of a C5a receptor antagonist in the rat after different sites of enteral administrationMorgan, Michael, Bulmer, Andrew C., Woodruff, Trent M., Proctor, Lavinia M., Williams, Hua M., Stocks, Shelli Z., Pollitt, Sandra, Taylor, Stephen M. and Shiels, Ian A (2008). Pharmacokinetics of a C5a receptor antagonist in the rat after different sites of enteral administration. European Journal of Pharmaceutical Sciences, 33 (4-5), 390-398. doi: 10.1016/j.ejps.2008.01.009 |
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2008 Journal Article Role of complement C5a in mechanical inflammatory hypernociception: potential use of C5a receptor antagonists to control inflammatory painTing, E., Guerrero, A. T. G., Cunha, T. M., Verri, W. A., Taylor, S. M., Woodruff, T. M., Cunha, F. Q. and Ferreira, S. H. (2008). Role of complement C5a in mechanical inflammatory hypernociception: potential use of C5a receptor antagonists to control inflammatory pain. British Journal of Pharmacology, 153 (5), 1043-1053. doi: 10.1038/sj.bjp.0707640 |
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2008 Journal Article Targeting ischemic brain injury with intravenous immunoglobulinArumugam, Thiruma V., Selvaraj, Pradeep K., Woodruff, Trent M. and Mattson, Mark P. (2008). Targeting ischemic brain injury with intravenous immunoglobulin. Expert Opinion on Therapeutic Targets, 12 (1), 19-29. doi: 10.1517/14728222.12.1.19 |
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2007 Journal Article The role of the N-terminal domain of the complement fragment receptor C5L2 in ligand bindingScola, A. M., Higginbottom, A., Partridge, L, J., Reid, R. C., Woodruff, T., Taylor, S. M., Fairlie, D. P. and Monk, P. N. (2007). The role of the N-terminal domain of the complement fragment receptor C5L2 in ligand binding. Journal of Biological Chemistry, 282 (6), 3664-3671. doi: 10.1074/jbc.M609178200 |
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2006 Journal Article Complement mediators in ischemia-reperfusion injuryArumugam, Thiruma V., Magnus, Tim, Woodruff, Trent M., Proctor, Lavinia M., Shiels, Ian A., Taylor, Stephen M., A. H. Wu and J. Delanghe (2006). Complement mediators in ischemia-reperfusion injury. Clinica Chimica Acta, 374 (1-2), 33-45. doi: 10.1016/j.cca.2006.06.010 |
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2006 Journal Article Transdermal pharmacology of small molecule cyclic C5a antagonistsProctor, Lavinia M, Woodruff, Trent M, Sharma, Prakirti, Shiels, Ian A and Taylor, Stephen M (2006). Transdermal pharmacology of small molecule cyclic C5a antagonists. Advances in experimental medicine and biology, 586, 329-345. |
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2006 Journal Article Complement inhibitors selectively attenuate injury following administration of cobra venom factor to ratsProctor, Lavinia M., Strachan, Anna J., Woodruff, Trent M., Mahadevan, Indumathy B., Williams, H. Ming, Shiels, Ian A. and Taylor, Stephen M. (2006). Complement inhibitors selectively attenuate injury following administration of cobra venom factor to rats. International Immunopharmacology, 6 (8), 1224-1232. doi: 10.1016/j.intimp.2006.03.002 |
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2006 Journal Article Therapeutic activity of C5a receptor antagonists in a rat model of neurodegenerationWoodruff, Trent M., Crane, James W., Proctor, Lavinia. M., Buller, Kathryn M., Shek, Annie B., De Vos, Kurt, Pollitt, Sandra, Williams, Hua M., Shiels, Ian A., Monk, Peter N. and Taylor, Stephen M. (2006). Therapeutic activity of C5a receptor antagonists in a rat model of neurodegeneration. FASEB Journal, 20 (9), 1407-1417. doi: 10.1096/fj.05-5814com |
