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2017 Journal Article Non-invasive assessment of altered activity following restraint in mice using an automated physiological monitoring systemSpiers, Jereme G., Chen, Hsiao-Jou Cortina, Steyn, Frederik J., Lavidis, Nickolas A., Woodruff, Trent M. and Lee, John D. (2017). Non-invasive assessment of altered activity following restraint in mice using an automated physiological monitoring system. Stress, 20 (1), 59-67. doi: 10.1080/10253890.2016.1276898 |
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2016 Journal Article Complement in the fundamental processes of the cellHawksworth, Owen A., Coulthard, Liam G. and Woodruff, Trent M. (2016). Complement in the fundamental processes of the cell. Molecular Immunology, 84, 17-25. doi: 10.1016/j.molimm.2016.11.010 |
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2016 Journal Article Prokineticin-2 upregulation during neuronal injury mediates a compensatory protective response against dopaminergic neuronal degenerationGordon, Richard, Neal, Matthew L., Luo, Jie, Langley, Monica R., Harischandra, Dilshan S., Panicker, Nikhil, Charli, Adhithiya, Jin, Huajun, Anantharam, Vellareddy, Woodruff, Trent M., Zhou, Qun-Yong, Kanthasamy, Anumantha G. and Kanthasamy, Arthi (2016). Prokineticin-2 upregulation during neuronal injury mediates a compensatory protective response against dopaminergic neuronal degeneration. Nature Communications, 7 (1) 12932, 12932.1-12932.18. doi: 10.1038/ncomms12932 |
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2016 Journal Article Discovery of functionally selective C5aR2 ligands: novel modulators of C5a signallingCroker, Daniel E., Monk, Peter N., Halai, Reena, Kaeslin, Geraldine, Schofield, Zoe, Wu, Mike C. L., Clark, Richard J., Blaskovich, Mark A. T., Morikis, Dimitrios, Floudas, Christodoulos A., Cooper, Matthew and Woodruff, Trent M. (2016). Discovery of functionally selective C5aR2 ligands: novel modulators of C5a signalling. Immunology and Cell Biology, 94 (8), 787-795. doi: 10.1038/icb.2016.43 |
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2016 Journal Article Release of bioactive peptides from polyurethane films in vitro and in vivo: Effect of polymer compositionZhang, Jing, Woodruff, Trent M., Clark, Richard J., Martin, Darren J. and Minchin, Rodney F. (2016). Release of bioactive peptides from polyurethane films in vitro and in vivo: Effect of polymer composition. Acta Biomaterialia, 41, 264-272. doi: 10.1016/j.actbio.2016.05.034 |
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2016 Journal Article C5a induces caspase-dependent apoptosis in brain vascular endothelial cells in experimental lupusMahajan, Supriya D., Tutino, Vincent M., Redae, Yonas, Meng, Hui, Siddiqui, Adnan, Woodruff, Trent M., Jarvis, James N., Hennon, Teresa, Schwartz, Stanley, Quigg, Richard J. and Alexander, Jessy J. (2016). C5a induces caspase-dependent apoptosis in brain vascular endothelial cells in experimental lupus. Immunology, 148 (4), 407-419. doi: 10.1111/imm.12619 |
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2016 Journal Article Contribution of the anaphylatoxin receptors, C3aR and C5aR, to the pathogenesis of pulmonary fibrosisGu, Hongmei, Fisher, Amanda J., Mickler, Elizabeth A., Duerson, Frank, III, Cummings, Oscar W., Peters-Golden, Marc, Twigg, Homer L., III, Woodruff, Trent M., Wilkes, David S. and Vittal, Ragini (2016). Contribution of the anaphylatoxin receptors, C3aR and C5aR, to the pathogenesis of pulmonary fibrosis. FASEB Journal, 30 (6), 2336-2350. doi: 10.1096/fj.201500044 |
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2016 Journal Article The complement system component C5a produces thermal hyperalgesia via macrophage-to-nociceptor signaling that requires NGF and TRPV1Shutov, Leonid P., Warwick, Charles A., Shi, Xiaoyu, Gnanasekaran, Aswini, Shepherd, Andrew J., Mohapatra, Durga P., Woodruff, Trent M., David Clark, J. and Usachev, Yuriy M. (2016). The complement system component C5a produces thermal hyperalgesia via macrophage-to-nociceptor signaling that requires NGF and TRPV1. Journal of Neuroscience, 36 (18), 5055-5070. doi: 10.1523/JNEUROSCI.3249-15.2016 |
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2016 Journal Article The complement C3a receptor contributes to melanoma tumorigenesis by inhibiting neutrophil and CD4+ T cell responsesNabizadeh, Jamileh A., Manthey, Helga D., Steyn, Frederik J., Chen, Weiyu, Widiapradja, Alexander, Akhir, Fazrena N. Md, Boyle, Glen M., Taylor, Stephen M., Woodruff, Trent M. and Rolfe, Barbara E. (2016). The complement C3a receptor contributes to melanoma tumorigenesis by inhibiting neutrophil and CD4+ T cell responses. Journal of Immunology, 196 (11), 4783-4792. doi: 10.4049/jimmunol.1600210 |
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2016 Journal Article Autoantibodies against homocysteinylated protein in a mouse model of folate deficiency-induced neural tube defectsDenny, Kerina J., Kelly, Christina F., Kumar, Vinod, Witham, Katey L., Cabrera, Robert M., Fennell, Richard H., Taylor, Stephen M., Jeanes, Angela and Woodruff, Trent M. (2016). Autoantibodies against homocysteinylated protein in a mouse model of folate deficiency-induced neural tube defects. Birth Defects Research Part A: Clinical and Molecular Teratology, 106 (3), 201-207. doi: 10.1002/bdra.23483 |
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2016 Journal Article EPHA4-FC treatment reduces ischemia/reperfusion-induced intestinal injury by inhibiting vascular permeabilityWoodruff, Trent M., Wu, Mike C.-L., Morgan, Michael, Bain, Nathan T., Jeanes, Angela, Lipman, Jeffrey, Ting, Michael J., Boyd, Andrew W., Taylor, Stephen M. and Coulthard, Mark G. (2016). EPHA4-FC treatment reduces ischemia/reperfusion-induced intestinal injury by inhibiting vascular permeability. Shock, 45 (2), 184-191. doi: 10.1097/SHK.0000000000000494 |
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2016 Journal Article Therapeutic targeting of complement to modify disease course and improve outcomes in neurological conditionsBrennan, Faith H., Lee, John D., Ruitenberg, Marc J. and Woodruff, Trent M. (2016). Therapeutic targeting of complement to modify disease course and improve outcomes in neurological conditions. Seminars in Immunology, 28 (3), 292-308. doi: 10.1016/j.smim.2016.03.015 |
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2016 Journal Article Motor deficits associated with Huntington's disease occur in the absence of striatal degeneration in BACHD transgenic miceMantovani, Susanna, Gordon, Richard, Li, Rui, Christie, Daniel C., Kumar, Vinod and Woodruff, Trent M. (2016). Motor deficits associated with Huntington's disease occur in the absence of striatal degeneration in BACHD transgenic mice. Human Molecular Genetics, 25 (9) ddw050, 1780-1791. doi: 10.1093/hmg/ddw050 |
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2015 Journal Article The receptor for advanced glycation endproducts does not contribute to pathology in a mouse mesenteric ischemia/reperfusion-induced injury modelWu, Mike C. L., Gilmour, Timothy D., Mantovani, Susanna and Woodruff, Trent M. (2015). The receptor for advanced glycation endproducts does not contribute to pathology in a mouse mesenteric ischemia/reperfusion-induced injury model. Frontiers in Immunology, 6 (DEC) 614, 1-7. doi: 10.3389/fimmu.2015.00614 |
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2015 Journal Article Altered expression of metabolic proteins and adipokines in patients with amyotrophic lateral sclerosisNgo, S. T., Steyn, F. J., Huang, L., Mantovani, S., Pfluger, C. M. M., Woodruff, T. M., O'Sullivan, J. D., Henderson, R. D. and McCombe, P. A. (2015). Altered expression of metabolic proteins and adipokines in patients with amyotrophic lateral sclerosis. Journal of the Neurological Sciences, 357 (1-2), 22-27. doi: 10.1016/j.jns.2015.06.053 |
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2015 Journal Article Co-ordinated expression of innate immune molecules during mouse neurulationJeanes, Angela, Coulthard, Liam G., Mantovani, Susanna, Markham, Kathryn and Woodruff, Trent M. (2015). Co-ordinated expression of innate immune molecules during mouse neurulation. Molecular Immunology, 68 (2), 253-260. doi: 10.1016/j.molimm.2015.09.004 |
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2015 Journal Article Placental lipase expression in pregnancies complicated by preeclampsia: A case-control studyBarrett, Helen L., Kubala, Marta H., Scholz Romero, Katherin., Denny, Kerina J., Woodruff, Trent M., McIntyre, H.David., Callaway, Leonie K. and Dekker Nitert, Marloes. (2015). Placental lipase expression in pregnancies complicated by preeclampsia: A case-control study. Reproductive Biology and Endocrinology, 13 (1) 100, 100. doi: 10.1186/s12958-015-0098-9 |
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2015 Journal Article C5a alters blood-brain barrier integrity in a human in vitro model of systemic lupus erythematosusMahajan, Supriya D., Parikh, Neil U., Woodruff, Trent M., Jarvis, James N., Lopez, Molly, Hennon, Teresa, Cunningham, Patrick, Quigg, Richard J., Schwartz, Stanley A. and Alexander, Jessy J. (2015). C5a alters blood-brain barrier integrity in a human in vitro model of systemic lupus erythematosus. Immunology, 146 (1), 130-143. doi: 10.1111/imm.12489 |
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2015 Journal Article The role of C5a receptor signaling in endotoxin-induced miscarriage and preterm birthDenny, Kerina J., Coulthard, Liam G., Mantovani, Susanna, Simmons, David, Taylor, Stephen M. and Woodruff, Trent M. (2015). The role of C5a receptor signaling in endotoxin-induced miscarriage and preterm birth. American Journal of Reproductive Immunology, 74 (2), 148-155. doi: 10.1111/aji.12386 |
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2015 Journal Article Antiallodynic effects of alpha lipoic acid in an optimized RR-EAE mouse model of MS-neuropathic pain are accompanied by attenuation of upregulated BDNF-TrkB-ERK signalling in the dorsal horn of the spinal cordKhan, Nemat, Gordon, Richard, Woodruff, Trent M. and Smith, Maree T. (2015). Antiallodynic effects of alpha lipoic acid in an optimized RR-EAE mouse model of MS-neuropathic pain are accompanied by attenuation of upregulated BDNF-TrkB-ERK signalling in the dorsal horn of the spinal cord. Pharmacology Research and Perspectives, 3 (3) e00137, 1-16. doi: 10.1002/prp2.137 |
