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2014 Journal Article Multiple immune factors are involved in controlling acute and chronic chikungunya virus infectionPoo, Yee Suan, Rudd, Penny A., Gardner, Joy, Wilson, Jane A. C., Larcher, Thibaut, Colle, Marie-Anne, Le, Thuy T., Nakaya, Helder I., Warrilow, David, Allcock, Richard, Bielefeldt-Ohmann, Helle, Schroder, Wayne A., Khromykh, Alexander A., Lopez, Jose A. and Suhrbier, Andreas (2014). Multiple immune factors are involved in controlling acute and chronic chikungunya virus infection. PLoS Neglected Tropical Diseases, 8 (12) e3354, 1-15. doi: 10.1371/journal.pntd.0003354 |
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2014 Journal Article Programmed ribosomal frameshift alters expression of West Nile virus genes and facilitates virus replication in birds and mosquitoesMelian, Ezequiel Balmori, Hall-Mendelin, Sonja, Du, Fangyao, Owens, Nick, Bosco-Lauth, Angela M., Nagasaki, Tomoko, Rudd, Stephen, Brault, Aaron C., Bowen, Richard A., Hall, Roy A., van den Hurk, Andrew F. and Khromykh, Alexander A. (2014). Programmed ribosomal frameshift alters expression of West Nile virus genes and facilitates virus replication in birds and mosquitoes. PLoS Pathogens, 10 (11) e1004447, e1004447.1-e1004447.18. doi: 10.1371/journal.ppat.1004447 |
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2014 Journal Article The increased expression of capsid protein in trans enhances production of single-round infectious particles by West Nile virus DNA vaccine candidateRoby, Justin A., Bielefeldt-Ohmann, Helle, Prow, Natalie A., Chang, David C., Hall, Roy A. and Khromykh, Alexander A. (2014). The increased expression of capsid protein in trans enhances production of single-round infectious particles by West Nile virus DNA vaccine candidate. Journal of General Virology, 95 (10), 2176-2191. doi: 10.1099/vir.0.064121-0 |
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2014 Journal Article Expression of mosquito microRNA aae-miR-2940-5p is down-regulated in response to West Nile Virus infection to restrict viral replicationSlonchak, Andrii, Hussain, Mazhar, Torres Morales, Shessy, Asgari, Sassan and Khromykh, Alexander (2014). Expression of mosquito microRNA aae-miR-2940-5p is down-regulated in response to West Nile Virus infection to restrict viral replication. Journal of Virology, 88 (15), 8457-8467. doi: 10.1128/JVI.00317-14 |
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2014 Journal Article Wolbachia infection modifies the profile, shuttling and structure of MicroRNAs in a mosquito cell lineMayoral, Jamie G., Etebari, Kayvan, Hussain, Mazhar, Khromykh, Alexander A. and Asgari, Sassan (2014). Wolbachia infection modifies the profile, shuttling and structure of MicroRNAs in a mosquito cell line. PLoS One, 9 (4) e96107, e96107. doi: 10.1371/journal.pone.0096107 |
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2014 Journal Article Loop de loop: viral RNA evades IFIT1 targetingRoby, Justin A., Clarke, Brian D. and Khromykh, Alexander A. (2014). Loop de loop: viral RNA evades IFIT1 targeting. Trends In Microbiology, 22 (4), 171-173. doi: 10.1016/j.tim.2014.02.014 |
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2014 Journal Article Internal ribosome entry site-based attenuation of a flavivirus candidate vaccine and evaluation of the effect of beta interferon coexpression on vaccine propertiesFrese, Michael, Lee, Eva, Larena, Maximilian, Lim, Pek Siew, Rao, Sudha, Matthaei, Klaus I., Khromykh, Alexander, Ramshaw, Ian and Lobigs, Mario (2014). Internal ribosome entry site-based attenuation of a flavivirus candidate vaccine and evaluation of the effect of beta interferon coexpression on vaccine properties. Journal of Virology, 88 (4), 2056-2070. doi: 10.1128/JVI.03051-13 |
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2014 Journal Article Noncoding subgenomic flavivirus RNA: multiple functions in West Nile Virus pathogenesis and modulation of host responsesRoby, Justin A., Pijlman, Gorben P., Wilusz, Jeffrey and Khromykh, Alexander A. (2014). Noncoding subgenomic flavivirus RNA: multiple functions in West Nile Virus pathogenesis and modulation of host responses. Viruses, 6 (2), 404-427. doi: 10.3390/v6020404 |
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2014 Journal Article The West Nile virus assembly process evades the conserved antiviral mechanism of the interferon-induced MxA proteinHoenen, Antje, Gillespie, Leah, Morgan, Garry, van der Heide, Peter, Khromykh, Alexander and Mackenzie, Jason (2014). The West Nile virus assembly process evades the conserved antiviral mechanism of the interferon-induced MxA protein. Virology, 448, 104-116. doi: 10.1016/j.virol.2013.10.005 |
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2013 Journal Article West Nile virus genome with glycosylated envelope protein and deletion of alpha helixes 1, 2 and 4 in the capsid gene is non-infectious and efficiently secretes sub-viral particlesRoby, Justin A., Hall, Roy A. and Khromykh, Alexander A. (2013). West Nile virus genome with glycosylated envelope protein and deletion of alpha helixes 1, 2 and 4 in the capsid gene is non-infectious and efficiently secretes sub-viral particles. Journal of Virology, 87 (23), 13063-13069. doi: 10.1128/JVI.01552-13 |
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2013 Journal Article An interaction between the methyltransferase and RNA dependent RNA polymerase domains of the West Nile virus NS5 proteinTan, Cindy S. E., Hobson-Peters, Jody M., Stoermer, Martin J., Fairlie, David P., Khromykh, Alexander A. and Hall, Roy A. (2013). An interaction between the methyltransferase and RNA dependent RNA polymerase domains of the West Nile virus NS5 protein. Journal of General Virology, 94 (Pt. 9), 1961-1971. doi: 10.1099/vir.0.054395-0 |
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2013 Journal Article NS1' colocalizes with NS1 and can substitute for NS1 in West Nile virus replicationYoung, Lucy B., Melian, Ezequiel Balmori and Khromykh, Alexander A. (2013). NS1' colocalizes with NS1 and can substitute for NS1 in West Nile virus replication. Journal of Virology, 87 (16), 9384-9390. doi: 10.1128/JVI.01101-13 |
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2013 Journal Article West Nile virus NS2A protein facilitates virus-induced apoptosis independently of interferon responseMelian, Ezequiel Balmori, Edmonds, Judith H., Nagasaki, Tomoko Kim, Hinzman, Edward, Floden, Nadia and Khromykh, Alexander A. (2013). West Nile virus NS2A protein facilitates virus-induced apoptosis independently of interferon response. Journal of General Virology, 94 (Part 2), 308-313. doi: 10.1099/vir.0.047076-0 |
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2013 Journal Article A novel bacteria-free method for generation of flavivirus infectious DNA by circular polymerase extension reaction allows accurate recapitulation of viral heterogeneityEdmonds, Judith, van Grinsven, Erinke, Prow, Natalie, Bosco-Lauth, Angela, Brault, Aaron C., Bowen, Richard A., Hall, Roy and Khromykh, Alexander A. (2013). A novel bacteria-free method for generation of flavivirus infectious DNA by circular polymerase extension reaction allows accurate recapitulation of viral heterogeneity. Journal of Virology, 87 (4), 2367-2372. doi: 10.1128/JVI.03162-12 |
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2013 Journal Article Effect of Wolbachia on replication of West Nile Virus in mosquito cell line and adult mosquitoesHussain, Mazhar, Lu, Guangjin, Torres, Shessy, Edmonds, Judith H., Kay, Brian H., Khromykh, Alexander A. and Asgari, Sassan (2013). Effect of Wolbachia on replication of West Nile Virus in mosquito cell line and adult mosquitoes. Journal of Virology, 87 (2), 851-858. doi: 10.1128/JVI.01837-12 |
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2012 Journal Article Noncoding flavivirus RNA displays RNA interference suppressoractivity in insect and mammalian cellsSchnettler, Esther, Sterken, Mark G., Leung, Jason Y., Metz, Stefan W., Geertsema, Corinne, Goldbach, Rob W., Vlak, Just M., Kohl, Alain, Khromykh, Alexander A. and Pijlman, Gorben P. (2012). Noncoding flavivirus RNA displays RNA interference suppressoractivity in insect and mammalian cells. Journal of Virology, 86 (24), 13486-13500. doi: 10.1128/JVI.01104-12 |
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2012 Journal Article A noncoding RNA produced by arthropod-borne flaviviruses inhibits the cellular exoribonuclease XRN1 and alters host mRNA stabilityMoon, Stephanie L., Anderson, John R., Kumagai, Yutaro, Wilusz, Carol J., Akira, Shizuo, Khromykh, Alexander A. and Wilusz, Jeffrey (2012). A noncoding RNA produced by arthropod-borne flaviviruses inhibits the cellular exoribonuclease XRN1 and alters host mRNA stability. RNA, 18 (11), 2029-2040. doi: 10.1261/rna.034330.112 |
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2012 Journal Article Identification of residues in West Nile virus premembrane protein that influence viral particle secretion and virulenceSetoh, Y. X., Prow, N. A., Hobson-Peters, J., Lobigs, M., Young, P. R., Khromykh, A. A. and Hall, R. A. (2012). Identification of residues in West Nile virus premembrane protein that influence viral particle secretion and virulence. Journal of General Virology, 93 (Part 9), 1965-1975. doi: 10.1099/vir.0.044453-0 |
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2012 Journal Article Interferon response factors 3 and 7 protect against Chikungunya virus hemorrhagic fever and shockRudd, Penny A., Wilson, Jane, Gardner, Joy, Larcher, Thibaut, Babarit, Candice, Le, Thuy T., Anraku, Itaru, Kumagai, Yutaro, Loo, Yueh-Ming, Gale Jr, Michael, Akira, Shizuo, Khromykh, Alexander A. and Suhrbier, Andreas (2012). Interferon response factors 3 and 7 protect against Chikungunya virus hemorrhagic fever and shock. Journal of Virology, 86 (18), 9888-9898. doi: 10.1128/JVI.00956-12 |
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2012 Journal Article Characterization of virulent West Nile virus Kunjin Strain, Australia, 2011Frost, Melinda J., Zhang, Jing, Edmonds, Judith H., Prow, Natalie A., Gu, Xingnian, Davis, Rodney, Hornitzky, Christine, Arzey, Kathleen E., Finlaison, Deborah, Hick, Paul, Read, Andrew, Hobson-Peters, Jody, May, Fiona J., Doggett, Stephen L., Haniotis, John, Russell, Richard C., Hall, Roy A., Khromykh, Alexander A. and Kirkland, Peter D. (2012). Characterization of virulent West Nile virus Kunjin Strain, Australia, 2011. Emerging Infectious Diseases, 18 (5), 792-800. doi: 10.3201/eid1805.111720 |
