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2012 Journal Article Interferon response factors 3 and 7 protect against Chikungunya virus hemorrhagic fever and shockRudd, Penny A., Wilson, Jane, Gardner, Joy, Larcher, Thibaut, Babarit, Candice, Le, Thuy T., Anraku, Itaru, Kumagai, Yutaro, Loo, Yueh-Ming, Gale Jr, Michael, Akira, Shizuo, Khromykh, Alexander A. and Suhrbier, Andreas (2012). Interferon response factors 3 and 7 protect against Chikungunya virus hemorrhagic fever and shock. Journal of Virology, 86 (18), 9888-9898. doi: 10.1128/JVI.00956-12 |
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2012 Journal Article Characterization of virulent West Nile virus Kunjin Strain, Australia, 2011Frost, Melinda J., Zhang, Jing, Edmonds, Judith H., Prow, Natalie A., Gu, Xingnian, Davis, Rodney, Hornitzky, Christine, Arzey, Kathleen E., Finlaison, Deborah, Hick, Paul, Read, Andrew, Hobson-Peters, Jody, May, Fiona J., Doggett, Stephen L., Haniotis, John, Russell, Richard C., Hall, Roy A., Khromykh, Alexander A. and Kirkland, Peter D. (2012). Characterization of virulent West Nile virus Kunjin Strain, Australia, 2011. Emerging Infectious Diseases, 18 (5), 792-800. doi: 10.3201/eid1805.111720 |
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2012 Journal Article West Nile virus noncoding subgenomic RNA contributes to viral evasion of the type I interferon-mediated antiviral responseSchuessler, Andrea, Funk, Anneke, Lazear, Helen M., Cooper, Daphne A., Torres, Shessy, Daffis, Stephane, Jha, Babal Kant, Kumagai, Yutaro, Takeuchi, Osamu, Hertzog, Paul, Silverman, Robert, Akira, Shizuo, Barton, David J., Diamond, Michael S. and Khromykh, Alexander A. (2012). West Nile virus noncoding subgenomic RNA contributes to viral evasion of the type I interferon-mediated antiviral response. Journal of Virology, 86 (10), 5708-5718. doi: 10.1128/JVI.00207-12 |
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2012 Journal Article West Nile virus encodes a microRNA-like small RNA in the 3' untranslated region which up-regulates GATA4 mRNA and facilitates virus replication in mosquito cellsHussain, Mazhar, Torres, Shessy, Schnettler, Esther, Funk, Anneke, Grundhoff, Adam, Pijlman, Gorben P., Khromykh, Alexander A. and Asgari, Sassan (2012). West Nile virus encodes a microRNA-like small RNA in the 3' untranslated region which up-regulates GATA4 mRNA and facilitates virus replication in mosquito cells. Nucleic Acids Research, 40 (5), 2210-2223. doi: 10.1093/nar/gkr848 |
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2011 Journal Article Kunjin virus replicon-based vaccines expressing Ebola virus glycoprotein GP protect the guinea pig against lethal Ebola virus infectionReynard, O., Mokhonov, V., Mokhonova, E., Leung, J., Page, A., Mateo, M., Pyankova, O., Georges-Courbot, M. C., Raoul, H., Khromykh, A. A. and Volchkov, V. E. (2011). Kunjin virus replicon-based vaccines expressing Ebola virus glycoprotein GP protect the guinea pig against lethal Ebola virus infection. Journal of Infectious Diseases, 204 (3), S1060-S1065. doi: 10.1093/infdis/jir347 |
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2011 Journal Article Determinants of attenuation in the envelope protein of the flavivirus AlfuyProw, Natalie A., May, Fiona J., Westlake, Daniel J., Hurrelbrink, Robert J., Biron, Rebecca M., Leung, Jason Y., McMinn, Peter C., Clark, David C., Mackenzie, John S., Lobigs, Mario, Khromykh, Alexander A. and Hall, Roy A. (2011). Determinants of attenuation in the envelope protein of the flavivirus Alfuy. Journal of General Virology, 92 (10), 2286-2296. doi: 10.1099/vir.0.034793-0 |
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2011 Journal Article pDNA-lipoplexes engrafted with flagellin-related peptide induce potent immunity and anti-tumour effectsFaham, Abdus, Herringson, Thomas, Parish, Chris, Suhrbier, AandreaS, Khromykh, Alexander A. and Altin, Joseph G. (2011). pDNA-lipoplexes engrafted with flagellin-related peptide induce potent immunity and anti-tumour effects. Vaccine, 29 (40), 6911-6919. doi: 10.1016/j.vaccine.2011.07.045 |
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2011 Journal Article The naturally attenuated Kunjin strain of West Nile virus shows enhanced sensitivity to the host type I interferon responseDaffis, Stephane, Lazear, Helen M., Liu, Wen Jun, Audsley, Michelle, Engle, Michael, Khromykh, Alexander A. and Diamond, Michael S. (2011). The naturally attenuated Kunjin strain of West Nile virus shows enhanced sensitivity to the host type I interferon response. Journal of Virology, 85 (11), 5664-5668. doi: 10.1128/JVI.00232-11 |
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2011 Journal Article Virulence determinants between New York 99 and Kunjin strains of West Nile virusAudsley, Michelle, Edmonds, Judith, Liu, Wenjun, Mokhonov, Vlad, Mokhonova, Ekaterina, Melian, Ezequeil Balmori, Prow, Natalie, Hall, Roy A. and Khromykh, Alexander A. (2011). Virulence determinants between New York 99 and Kunjin strains of West Nile virus. Virology, 414 (1), 63-73. doi: 10.1016/j.virol.2011.03.008 |
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2011 Journal Article Prime-boost vaccinations using recombinant flavivirus replicon and vaccinia virus vaccines: An ELISPOT analysisRattanasena, Paweena, Anraku, Itaru, Gardner, Joy, Le, Thuy T., Wang, Xiang Ju, Khromykh, Alexander A. and Suhrbier, Andreas (2011). Prime-boost vaccinations using recombinant flavivirus replicon and vaccinia virus vaccines: An ELISPOT analysis. Immunology and Cell Biology, 89 (3), 426-436. doi: 10.1038/icb.2010.99 |
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2010 Journal Article RNA structures required for production of subgenomic flavivirus RNAFunk, Anneke, Truong, Katherine, Nagasaki, Tomoko, Torres, Shessy, Floden, Nadia, Balmori Melian, Ezequiel, Edmonds, Judy, Dong, Hongping, Shi, Pei-Yong and Khromykh, Alexander A. (2010). RNA structures required for production of subgenomic flavivirus RNA. Journal of Virology, 84 (21), 11407-11417. doi: 10.1128/JVI.01159-10 |
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2010 Journal Article Chikungunya virus nonstructural protein 2 inhibits type I/II interferon-stimulated JAK-STAT signalingFros, Jelke J., Liu, Wen Jun, Prow, Natalie A., Geertsema, Corinne, Ligtenberg, Maarten, Vanlandingham, Dana L., Schnettler, Esther, Vlak, Just M., Suhrbier, Andreas, Khromykh, Alexander A. and Pijlman, Gorben P. (2010). Chikungunya virus nonstructural protein 2 inhibits type I/II interferon-stimulated JAK-STAT signaling. Journal of Virology, 84 (20), 10877-10887. doi: 10.1128/JVI.00949-10 |
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2010 Journal Article Nanopatch-targeted skin vaccination against West Nile virus and chikungunya virus in miceProw, Tarl W., Chen, Xianfeng, Prow, Natalie A., Fernando, Germain J. P., Tan, Cindy S. E., Raphael, Anthony P., Chang, David, Ruutu, Merja P., Jenkins, Derek W. K., Pyke, Alyssa, Crichton, Michael L., Raphaelli, Kristin, Goh, Lucas Y. H., Frazer, Ian H., Roberts, Michael S., Gardner, Joy, Khromykh, Alexander A., Suhrbier, Andreas, Hall, Roy A. and Kendall, Mark A. F. (2010). Nanopatch-targeted skin vaccination against West Nile virus and chikungunya virus in mice. Small, 6 (16), 1776-1784. doi: 10.1002/smll.201000331 |
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2010 Journal Article The NS5 protein of the virulent West Nile virus NY99 strain is a potent antagonist of type I interferon-mediated JAK-STAT signalingLaurent-Rolle, Maudry, Boer, Elena F., Lubick, Kirk J., Wolfinbarger, James B., Carmody, Aaron B., Rockx, Barry, Liu, Wenjun, Ashour, Joseph, Shupert, W. Lesley, Holbrook, Michael R., Barrett, Alan D., Mason, Peter W., Bloom, Marshall E., Garcia-Sastre, Adolfo, Khromykh, Alexander A. and Best, Sonja M. (2010). The NS5 protein of the virulent West Nile virus NY99 strain is a potent antagonist of type I interferon-mediated JAK-STAT signaling. Journal of Virology, 84 (7), 3503-3515. doi: 10.1128/JVI.01161-09 |
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2010 Journal Article Viral determinants in the NS3 helicase and 2K peptide that promote West Nile virus resistance to antiviral action of 2′,5′-oligoadenylate synthetase 1bMertens, E, Kajaste-Rudnitski, A, Torres, S, Funk, A, Frenkiel, MP, Iteman, I, Khromykh, AA and Despres, P (2010). Viral determinants in the NS3 helicase and 2K peptide that promote West Nile virus resistance to antiviral action of 2′,5′-oligoadenylate synthetase 1b. Virology, 399 (1), 176-185. doi: 10.1016/j.virol.2009.12.036 |
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2010 Journal Article NS1 ' of flaviviruses in the Japanese encephalitis virus serogroup is a product of ribosomal frameshifting and plays a role in viral neuroinvasivenessBalmori Melian, Ezequiel, Hinzman, Edward, Nagasaki, Tomoko, Firth, Andrew E., Wills, Norma M., Nouwens, Amanda S., Blitvich, Bradley J., Leung, Jason, Funk, Anneke, Atkins, John F., Hall, Roy and Khromykh, Alexander A. (2010). NS1 ' of flaviviruses in the Japanese encephalitis virus serogroup is a product of ribosomal frameshifting and plays a role in viral neuroinvasiveness. Journal of Virology, 84 (3), 1641-1647. doi: 10.1128/JVI.01979-09 |
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2009 Journal Article Monoclonal antibodies to the West Nile virus NS5 protein map to linear and conformational epitopes in the methyltransferase and polymerase domainsHall, Roy A., Tan, Si En, Selisko, Barbara, Slade, Rachael, Hobson-Peters, Jody, Canard, Bruno, Hughes, Megan, Leung, Jason Y., Balmori-Melian, Ezequiel, Hall-Mendelin, Sonja, Pham, Kim B., Clark, David C., Prow, Natalie A. and Khromykh, Alexander A. (2009). Monoclonal antibodies to the West Nile virus NS5 protein map to linear and conformational epitopes in the methyltransferase and polymerase domains. Journal of General Virology, 90 (12), 2912-2922. doi: 10.1099/vir.0.013805-0 |
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2009 Journal Article Generating flavivirus vaccine candidates by modulating interferon sensitivityFunk, Anneke and Khromykh, Alexander (2009). Generating flavivirus vaccine candidates by modulating interferon sensitivity. Expert Review of Vaccines, 8 (9), 1157-1160. doi: 10.1586/ERV.09.73 |
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2009 Journal Article West Nile virus: The current climateProw, Natalie A., Khromykh, Alexander A. and Hall, Roy A. (2009). West Nile virus: The current climate. Medical Laboratory Observer, 41 (4), 10-15. |
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2009 Journal Article A Kunjin replicon vector encoding granulocyte macrophage colony-stimulating factor for intra-tumoral gene therapyHoang-Le, D., Smeenk, L., Anraku, I., Pijlman, G. P., Wang, X. J., De Vrij, J., Liu, W. J., Le, T. T., Schroder, W. A., Khromykh, Alexander A. and Suhrbier, A. (2009). A Kunjin replicon vector encoding granulocyte macrophage colony-stimulating factor for intra-tumoral gene therapy. Gene Therapy, 16 (2), 190-199. doi: 10.1038/gt.2008.169 |
