Overview
Background
Dr Craig Bell is an Industry Fellow with the Australian Institute for Bioengineering and Nanotechnology, and the Centre for Advanced Imaging. Since obtaining his PhD in 2011, he has been the recipient of two international fellowships, a prestigious Newton International Fellowship (2013-2014) funded by the Royal Society, and the NHMRC CJ Martin Early Career Fellowship (2014-2018). He has contributed scientific articles to various leading journals in his field, and is the co-inventor on two patents. His current research focus is on the development of degradable polymer devices for imaging and tracking of disease and cellular processes by using a tool-kit of controlled polymerisation techniques along with polymer and molecular coupling methodologies. The incorporation of degradable moieties into these constructs not only allows for enzymatic and hydrolytic degradation for complete body clearance of these constructs but also allows for tracking of these devices in vivo upon degradation to help elucidate cellular processes. Dr Bell currently engages with Aegros, a membrane fabrication and human serum fractionation company based in Sydney.
Availability
- Dr Craig Bell is:
- Available for supervision
Fields of research
Qualifications
- Bachelor of Science, The University of Queensland
- Doctor of Philosophy, The University of Queensland
Research impacts
Design and synthesis of degradable polymeric materials that can be applied to molecular imaging and drug delivery in nanomedicine.
Works
Search Professor Craig Bell’s works on UQ eSpace
Featured
2016
Journal Article
Independent control of elastomer properties through stereocontrolled synthesis
Bell, Craig A., Yu,Jiayi, Barker, Ian A., Truong, Vinh X., Cao, Zhen, Dobrinyin, Andrey V., Becker, Matthew L. and Dove, Andrew P. (2016). Independent control of elastomer properties through stereocontrolled synthesis. Angewandte Chemie - International Edition, 55 (42), 13076-13080. doi: 10.1002/anie.201606750
Featured
2014
Journal Article
Functional degradable polymers by xanthate-mediated polymerization
Hedir, Guillaume G., Bell, Craig A., Leong, Nga Sze, Chapman, Emma, Collins, Ian R., O'Reilly, Rachel K. and Dove, Andrew P. (2014). Functional degradable polymers by xanthate-mediated polymerization. Macromolecules, 47 (9), 2847-2852. doi: 10.1021/ma500428e
Featured
2011
Journal Article
A rapid electrochemical method for determining rate coefficients for copper-catalyzed polymerizations
Bell, Craig A., Bernhardt, Paul V. and Monteiro, Michael J. (2011). A rapid electrochemical method for determining rate coefficients for copper-catalyzed polymerizations. Journal of the American Chemical Society, 133 (31), 11944-11947. doi: 10.1021/ja205193f
Featured
2011
Journal Article
Directing the pathway of orthogonal 'click' reactions by modulating copper-catalytic activity
Jia, Zhongfan, Bell, Craig A. and Monteiro, Michael J. (2011). Directing the pathway of orthogonal 'click' reactions by modulating copper-catalytic activity. Chemical Communications, 47 (14), 4165-4167. doi: 10.1039/c0cc05478j
Featured
2006
Journal Article
Surface-functionalized polymer nanoparticles for selective sequestering of heavy metals
Bell, C. A., Smith, S. V., Whittaker, M. R., Whittaker, A. K., Gahan, L. R. and Monteiro, M. J. (2006). Surface-functionalized polymer nanoparticles for selective sequestering of heavy metals. Advanced Materials, 18 (5), 582-586. doi: 10.1002/adma.200501712
2024
Journal Article
Material Trends and Clinical Costings in Systematically Identified CDER‐Approved Nanomedicines
Jarrett, Thomas Ryan, Pregelj, Lisette, Bell, Craig Andrew, Fletcher, Nicholas Lyle and Thurecht, Kristofer James (2024). Material Trends and Clinical Costings in Systematically Identified CDER‐Approved Nanomedicines. Advanced Therapeutics. doi: 10.1002/adtp.202400124
2024
Journal Article
Mitigating the effects of persistent antipolymer immune reactions in nanomedicine: Evaluating materials-based approaches using molecular imaging
Humphries, James, Fletcher, Nicholas L., Sonderegger, Stefan E., Bell, Craig A., Kempe, Kristian and Thurecht, Kristofer J. (2024). Mitigating the effects of persistent antipolymer immune reactions in nanomedicine: Evaluating materials-based approaches using molecular imaging. ACS Nano, 18 (30), 19890-19904. doi: 10.1021/acsnano.4c07317
2024
Journal Article
Biodegradable mPEG-<i>b</i>-poly(MDO-<i>co</i>-vinyl esters) block copolymers as a viable nanocarrier platform with tuneable disassembly
Balaji, Arunpandian, Prior, Amber R., O'Reilly, Rachel K., Dove, Andrew P., Thurecht, Kristofer J. and Bell, Craig A. (2024). Biodegradable mPEG-b-poly(MDO-co-vinyl esters) block copolymers as a viable nanocarrier platform with tuneable disassembly. Polymer Chemistry, 15 (12), 1152-1165. doi: 10.1039/d4py00049h
2024
Journal Article
Comparison of the hydrophilicity of water-soluble poly(2-alkyl-2-oxazoline)s, poly(2-alkyl-2-oxazine)s and poly(2,4-dialkyl-2-oxazoline)s
Mint, Kelly, Morrow, Joshua P., Warne, Nicole M., He, Xie, Pizzi, David, Shah, Shaffiq Zainal Osman, Pierens, Gregory K., Fletcher, Nicholas L., Bell, Craig A., Thurecht, Kristofer J. and Kempe, Kristian (2024). Comparison of the hydrophilicity of water-soluble poly(2-alkyl-2-oxazoline)s, poly(2-alkyl-2-oxazine)s and poly(2,4-dialkyl-2-oxazoline)s. Polymer Chemistry, 15 (26), 2662-2676. doi: 10.1039/d4py00332b
2023
Journal Article
Exploring the impact of severity in hepatic fibrosis disease on the intrahepatic distribution of novel biodegradable nanoparticles targeted towards different disease biomarkers
Balaji, Arunpandian, Bell, Craig A., Houston, Zachary H., Bridle, Kim R., Genz, Berit, Fletcher, Nicholas L., Ramm, Grant A. and Thurecht, Kristofer J. (2023). Exploring the impact of severity in hepatic fibrosis disease on the intrahepatic distribution of novel biodegradable nanoparticles targeted towards different disease biomarkers. Biomaterials, 302 122318, 1-18. doi: 10.1016/j.biomaterials.2023.122318
2023
Journal Article
Click‐on antibody fragments for customisable targeted nanomedicines – site‐specific tetrazine and azide functionalisation through non‐canonical amino acid incorporation
Huda, Pie, Humphries, James, Fletcher, Nicholas L., Howard, Christopher B., Thurecht, Kristofer J. and Bell, Craig A. (2023). Click‐on antibody fragments for customisable targeted nanomedicines – site‐specific tetrazine and azide functionalisation through non‐canonical amino acid incorporation. Chemistry–Methods, 4 (2) e202300036. doi: 10.1002/cmtd.202300036
2023
Journal Article
Recent advances and future perspectives in engineering biodegradable face masks
Athukoralalage, Sandya S. A., Bell, Craig A., Gemmell, Anna C., Rowan, Alan E. and Amiralian, Nasim (2023). Recent advances and future perspectives in engineering biodegradable face masks. Journal of Materials Chemistry A, 11 (4), 1575-1592. doi: 10.1039/d2ta08019b
2022
Journal Article
Probing the biocompatibility and immune cell association of chiral, water-soluble, bottlebrush poly(2-oxazoline)s
Pizzi, David, Humphries, James, Morrow, Joshua P., Mahmoud, Ayaat M., Fletcher, Nicholas L., Sonderegger, Stefan E., Bell, Craig A., Thurecht, Kristofer J. and Kempe, Kristian (2022). Probing the biocompatibility and immune cell association of chiral, water-soluble, bottlebrush poly(2-oxazoline)s. Biomacromolecules, 24 (1), 246-257. doi: 10.1021/acs.biomac.2c01105
2022
Journal Article
Pre-targeting of polymeric nanomaterials to balance tumour accumulation and clearance
Fletcher, N. L., Prior, A., Choy, O., Humphries, J., Huda, P., Ghosh, S., Houston, Z. H., Bell, C. A. and Thurecht, K. J. (2022). Pre-targeting of polymeric nanomaterials to balance tumour accumulation and clearance. Chemical Communications, 58 (57), 7912-7915. doi: 10.1039/d2cc02443h
2022
Journal Article
Development of targeted micelles and polymersomes prepared from degradable RAFT-based diblock copolymers and their potential role as nanocarriers for chemotherapeutics
Ahmed, Salma E., Fletcher, Nicholas L., Prior, Amber R., Huda, Pie, Bell, Craig A. and Thurecht, Kristofer J. (2022). Development of targeted micelles and polymersomes prepared from degradable RAFT-based diblock copolymers and their potential role as nanocarriers for chemotherapeutics. Polymer Chemistry, 13 (27), 4004-4017. doi: 10.1039/d2py00257d
2022
Journal Article
Understanding nanomedicine treatment in an aggressive spontaneous brain cancer model at the stage of early blood brain barrier disruption
Janowicz, Phillip W., Houston, Zachary H., Bunt, Jens, Fletcher, Nicholas L., Bell, Craig A., Cowin, Gary, Howard, Christopher B., Taslima, Dewan, Westra van Holthe, Nicholas, Prior, Amber, Soh, Vanessa, Ghosh, Saikat, Humphries, James, Huda, Pie, Mahler, Stephen M., Richards, Linda J. and Thurecht, Kristofer J. (2022). Understanding nanomedicine treatment in an aggressive spontaneous brain cancer model at the stage of early blood brain barrier disruption. Biomaterials, 283 121416, 121416. doi: 10.1016/j.biomaterials.2022.121416
2022
Journal Article
Simple synthetic route to a self-assembling enzyme-inspired transesterification catalysts
Kumar, Ashwani, Nothling, Mitchell David, Aitken, Heather M., Xiao, Zeyun, Lam, Mathew, Bell, Craig, O'Mara, Megan and Connal, Luke Andrew (2022). Simple synthetic route to a self-assembling enzyme-inspired transesterification catalysts. Catalysis Science and Technology, 12 (22), 6655-6659. doi: 10.1039/d2cy00744d
2021
Journal Article
Concomitant control of mechanical properties and degradation in resorbable elastomer-like materials using stereochemistry and stoichiometry for soft tissue engineering
Wandel, Mary Beth, Bell, Craig A., Yu, Jiayi, Arno, Maria C., Dreger, Nathan Z., Hsu, Yen-Hao, Pitto-Barry, Anaïs, Worch, Joshua C., Dove, Andrew P. and Becker, Matthew L. (2021). Concomitant control of mechanical properties and degradation in resorbable elastomer-like materials using stereochemistry and stoichiometry for soft tissue engineering. Nature Communications, 12 (1) 446. doi: 10.1038/s41467-020-20610-5
2021
Journal Article
Optimisation of alendronate conjugation to polyethylene glycol for functionalisation of biopolymers and nanoparticles
Poli, Hamish, Mushtaq, Asim, Bell, Craig A., McGeary, Ross P., Grøndahl, Lisbeth and A, Anitha (2021). Optimisation of alendronate conjugation to polyethylene glycol for functionalisation of biopolymers and nanoparticles. European Polymer Journal, 155 110571, 110571. doi: 10.1016/j.eurpolymj.2021.110571
2021
Journal Article
Cyanine-5-driven behaviours of hyperbranched polymers designed for therapeutic delivery are cell-type specific and correlated with polar lipid distribution in membranes
Simpson, Joshua D., Currin-Ross, Denni L., Ediriweera, Gayathri R., Schirra, Horst Joachim, Fletcher, Nicholas L., Bell, Craig A., Arno, Maria C. and Thurecht, Kristofer J. (2021). Cyanine-5-driven behaviours of hyperbranched polymers designed for therapeutic delivery are cell-type specific and correlated with polar lipid distribution in membranes. Nanomaterials, 11 (7) 1745, 1-18. doi: 10.3390/nano11071745
Supervision
Availability
- Dr Craig Bell is:
- Available for supervision
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Supervision history
Current supervision
-
Doctor Philosophy
Development of novel polymer-protein conjugates
Associate Advisor
Other advisors: Associate Professor Idriss Blakey, Professor Kristofer Thurecht
-
Doctor Philosophy
Methods for protein structure analysis using spin labelling, electron paramagnetic resonance spectroscopy and molecular modelling
Associate Advisor
Other advisors: Professor Bostjan Kobe, Dr Rhia Stone, Associate Professor Jeffrey Harmer
-
Doctor Philosophy
Aqueous one-pot photoinitiated polymerization-induced self-assembly (photo-PISA) to synthesize therapeutic protein loaded nanocarriers
Associate Advisor
Other advisors: Professor Kristofer Thurecht, Dr Gayathri Ediriweera
-
Doctor Philosophy
Novel complementary diagnostics for improved therapeutics/theranostics
Associate Advisor
Other advisors: Dr Nick Fletcher, Dr Rhia Stone, Professor Kristofer Thurecht
Completed supervision
-
2023
Doctor Philosophy
Design of pH-sensitive, polymeric nanoparticles, and their application in chemotherapeutic drug delivery
Associate Advisor
Other advisors: Dr Nick Fletcher, Professor Kristofer Thurecht
-
2023
Doctor Philosophy
Understanding Immunogenicity in Nanomedicine
Associate Advisor
Other advisors: Dr Nick Fletcher, Dr Pie Huda, Professor Kristofer Thurecht
-
2023
Doctor Philosophy
Photoacoustic Molecular Imaging in Nanomedicine: Development of a Polymeric Probe to Assess Tumour Penetration and Reassessment of the Contrast Enhancement Mechanism
Associate Advisor
Other advisors: Professor Kristofer Thurecht
-
2021
Doctor Philosophy
Self-assembled polymeric theranostics for hepatic fibrosis - An approach to non-invasive staging and targeted drug delivery
Associate Advisor
Other advisors: Professor Kristofer Thurecht
-
2021
Doctor Philosophy
Biological Interactions of Polymeric Nanomedicines & Molecular Imaging Agents
Associate Advisor
Other advisors: Dr Nick Fletcher, Professor Kristofer Thurecht
-
2020
Doctor Philosophy
Development of polymeric theranostics using bioorthogonal chemistry
Associate Advisor
Other advisors: Professor Kristofer Thurecht
-
2020
Doctor Philosophy
Design and synthesis of nanomaterials as combination therapeutics
Associate Advisor
Other advisors: Professor Kristofer Thurecht
-
2018
Doctor Philosophy
Development of novel polymeric theranostic for the treatment of colorectal cancer
Associate Advisor
Other advisors: Professor Kristofer Thurecht
Media
Enquiries
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