Overview
Background
Dr Craig Bell is an Industry Fellow with the Australian Institute for Bioengineering and Nanotechnology, and the Centre for Advanced Imaging. Since obtaining his PhD in 2011, he has been the recipient of two international fellowships, a prestigious Newton International Fellowship (2013-2014) funded by the Royal Society, and the NHMRC CJ Martin Early Career Fellowship (2014-2018). He has contributed scientific articles to various leading journals in his field, and is the co-inventor on two patents. His current research focus is on the development of degradable polymer devices for imaging and tracking of disease and cellular processes by using a tool-kit of controlled polymerisation techniques along with polymer and molecular coupling methodologies. The incorporation of degradable moieties into these constructs not only allows for enzymatic and hydrolytic degradation for complete body clearance of these constructs but also allows for tracking of these devices in vivo upon degradation to help elucidate cellular processes. Dr Bell currently engages with Aegros, a membrane fabrication and human serum fractionation company based in Sydney.
Availability
- Dr Craig Bell is:
- Available for supervision
Fields of research
Qualifications
- Bachelor of Science, The University of Queensland
- Doctor of Philosophy, The University of Queensland
Research impacts
Design and synthesis of degradable polymeric materials that can be applied to molecular imaging and drug delivery in nanomedicine.
Works
Search Professor Craig Bell’s works on UQ eSpace
2022
Journal Article
Understanding nanomedicine treatment in an aggressive spontaneous brain cancer model at the stage of early blood brain barrier disruption
Janowicz, Phillip W., Houston, Zachary H., Bunt, Jens, Fletcher, Nicholas L., Bell, Craig A., Cowin, Gary, Howard, Christopher B., Taslima, Dewan, Westra van Holthe, Nicholas, Prior, Amber, Soh, Vanessa, Ghosh, Saikat, Humphries, James, Huda, Pie, Mahler, Stephen M., Richards, Linda J. and Thurecht, Kristofer J. (2022). Understanding nanomedicine treatment in an aggressive spontaneous brain cancer model at the stage of early blood brain barrier disruption. Biomaterials, 283 121416, 121416. doi: 10.1016/j.biomaterials.2022.121416
2022
Journal Article
Simple synthetic route to a self-assembling enzyme-inspired transesterification catalysts
Kumar, Ashwani, Nothling, Mitchell David, Aitken, Heather M., Xiao, Zeyun, Lam, Mathew, Bell, Craig, O'Mara, Megan and Connal, Luke Andrew (2022). Simple synthetic route to a self-assembling enzyme-inspired transesterification catalysts. Catalysis Science and Technology, 12 (22), 6655-6659. doi: 10.1039/d2cy00744d
2021
Journal Article
Concomitant control of mechanical properties and degradation in resorbable elastomer-like materials using stereochemistry and stoichiometry for soft tissue engineering
Wandel, Mary Beth, Bell, Craig A., Yu, Jiayi, Arno, Maria C., Dreger, Nathan Z., Hsu, Yen-Hao, Pitto-Barry, Anaïs, Worch, Joshua C., Dove, Andrew P. and Becker, Matthew L. (2021). Concomitant control of mechanical properties and degradation in resorbable elastomer-like materials using stereochemistry and stoichiometry for soft tissue engineering. Nature Communications, 12 (1) 446. doi: 10.1038/s41467-020-20610-5
2021
Journal Article
Optimisation of alendronate conjugation to polyethylene glycol for functionalisation of biopolymers and nanoparticles
Poli, Hamish, Mushtaq, Asim, Bell, Craig A., McGeary, Ross P., Grøndahl, Lisbeth and A, Anitha (2021). Optimisation of alendronate conjugation to polyethylene glycol for functionalisation of biopolymers and nanoparticles. European Polymer Journal, 155 110571, 110571. doi: 10.1016/j.eurpolymj.2021.110571
2021
Journal Article
Cyanine-5-driven behaviours of hyperbranched polymers designed for therapeutic delivery are cell-type specific and correlated with polar lipid distribution in membranes
Simpson, Joshua D., Currin-Ross, Denni L., Ediriweera, Gayathri R., Schirra, Horst Joachim, Fletcher, Nicholas L., Bell, Craig A., Arno, Maria C. and Thurecht, Kristofer J. (2021). Cyanine-5-driven behaviours of hyperbranched polymers designed for therapeutic delivery are cell-type specific and correlated with polar lipid distribution in membranes. Nanomaterials, 11 (7) 1745, 1-18. doi: 10.3390/nano11071745
2021
Journal Article
Poly(2-ethyl-2-oxazoline) bottlebrushes: How nanomaterial dimensions can influence biological interactions
Pizzi, David, Mahmoud, Ayaat M., Klein, Tobias, Morrow, Joshua P., Humphries, James, Houston, Zachary H., Fletcher, Nicholas L., Bell, Craig A., Thurecht, Kristofer J. and Kempe, Kristian (2021). Poly(2-ethyl-2-oxazoline) bottlebrushes: How nanomaterial dimensions can influence biological interactions. European Polymer Journal, 151 110447, 1-9. doi: 10.1016/j.eurpolymj.2021.110447
2021
Other Outputs
Biomimetic synthetic rubber and methods for controlling its physical properties through backbone double bond stereochemistry by monomer selection and end group modification
Becker, Matthew L., Dove, Andrew P., Truong, Vinh X., Bell, Craig A., Barker, Ian A. and Yu, Jiayi (2021). Biomimetic synthetic rubber and methods for controlling its physical properties through backbone double bond stereochemistry by monomer selection and end group modification. US10968303.
2021
Journal Article
Thermally-induced hyperbranching of bromine-containing polyesters by insertion of in situ generated chain-end carbenes dagger
Bexis, Panagiotis, Arno, Maria C., Bell, Craig A., Thomas, Anthony W. and Dove, Andrew P. (2021). Thermally-induced hyperbranching of bromine-containing polyesters by insertion of in situ generated chain-end carbenes dagger. Chemical Communications, 57 (35), 4275-4278. doi: 10.1039/d1cc00821h
2021
Journal Article
Fluorophore selection and incorporation contribute to permeation and distribution behaviors of hyperbranched polymers in multi-cellular tumor spheroids and xenograft tumor models
Simpson, Joshua D., Monteiro, Patrícia F., Ediriweera, Gayathri R., Prior, Amber R., Sonderegger, Stefan E., Bell, Craig A., Fletcher, Nicholas L., Alexander, Cameron and Thurecht, Kristofer J. (2021). Fluorophore selection and incorporation contribute to permeation and distribution behaviors of hyperbranched polymers in multi-cellular tumor spheroids and xenograft tumor models. ACS Applied Bio Materials, 4 (3) acsabm.0c01616, 2675-2685. doi: 10.1021/acsabm.0c01616
2021
Journal Article
Curcumin chemoprevention reduces the incidence of Braf mutant colorectal cancer in a preclinical study
Kane, Alexandra M., Liu, Cheng, Akhter, Dewan T., McKeone, Diane M., Bell, Craig A., Thurecht, Kristofer J., Leggett, Barbara A. and Whitehall, Vicki L. J. (2021). Curcumin chemoprevention reduces the incidence of Braf mutant colorectal cancer in a preclinical study. Digestive Diseases and Sciences, 66 (12), 4326-4332. doi: 10.1007/s10620-020-06752-y
2021
Journal Article
Understanding the role of colon-specific microparticles based on retrograded starch/pectin in the delivery of chitosan nanoparticles along the gastrointestinal tract
dos Santos, Aline Martins, Meneguin, Andréia Bagliotti, Akhter, Dewan Taslima, Fletcher, Nicholas, Houston, Zachary H., Bell, Craig, Thurecht, Kristofer J. and Gremião, Maria Palmira Daflon (2021). Understanding the role of colon-specific microparticles based on retrograded starch/pectin in the delivery of chitosan nanoparticles along the gastrointestinal tract. European Journal of Pharmaceutics and Biopharmaceutics, 158, 371-378. doi: 10.1016/j.ejpb.2020.12.004
2020
Journal Article
Effect of chain‐end chemistries on the efficiency of coupling antibodies to polymers using unnatural amino acids
Sivaram, Amal J., Wardiana, Andri, Preethi, S. S. Hema, Fuchs, Adrian V., Howard, Christopher B., Fletcher, Nicholas L., Bell, Craig A. and Thurecht, Kristofer J. (2020). Effect of chain‐end chemistries on the efficiency of coupling antibodies to polymers using unnatural amino acids. Macromolecular Rapid Communications, 41 (21) 2000294, e2000294. doi: 10.1002/marc.202000294
2020
Journal Article
Person-specific biomolecular coronas modulate nanoparticle interactions with immune cells in human blood
Ju, Yi, Kelly, Hannah G., Dagley, Laura F., Reynaldi, Arnold, Schlub, Timothy E., Spall, Sukhdeep K., Bell, Craig A., Cui, Jiwei, Mitchell, Andrew J., Lin, Zhixing, Wheatley, Adam K., Thurecht, Kristofer J., Davenport, Miles P., Webb, Andrew I., Caruso, Frank and Kent, Stephen J. (2020). Person-specific biomolecular coronas modulate nanoparticle interactions with immune cells in human blood. ACS Nano, 14 (11) acsnano.0c06679, 15723-15737. doi: 10.1021/acsnano.0c06679
2020
Journal Article
Controlling the biological fate of micellar nanoparticles: balancing stealth and targeting
Sivaram, Amal J., Wardiana, Andri, Alcantara, Sheilajen, Sonderegger, Stefan E., Fletcher, Nicholas L., Houston, Zachary H., Howard, Christopher B., Mahler, Stephen M., Alexander, Cameron, Kent, Stephen J., Bell, Craig A. and Thurecht, Kristofer J. (2020). Controlling the biological fate of micellar nanoparticles: balancing stealth and targeting. ACS Nano, 14 (10) acsnano.0c06033, 13739-13753. doi: 10.1021/acsnano.0c06033
2020
Journal Article
Hyperbranched Poly(2-oxazoline)s and Poly(ethylene glycol): A structure–activity comparison of biodistribution
Humphries, James, Pizzi, David, Sonderegger, Stefan E., Fletcher, Nicholas L., Houston, Zachary H., Bell, Craig A., Kempe, Kristian and Thurecht, Kristofer J. (2020). Hyperbranched Poly(2-oxazoline)s and Poly(ethylene glycol): A structure–activity comparison of biodistribution. Biomacromolecules, 21 (8) acs.biomac.0c00765, 3318-3331. doi: 10.1021/acs.biomac.0c00765
2020
Journal Article
Tuning of the aggregation behavior of fluorinated polymeric nanoparticles for improved therapeutic efficacy
Zhang, Cheng, Liu, Tianqing, Wang, Wenqian, Bell, Craig A., Han, Yanxiao, Fu, Changkui, Peng, Hui, Tan, Xiao, Král, Petr, Gaus, Katharina, Gooding, J. Justin and Whittaker, Andrew K. (2020). Tuning of the aggregation behavior of fluorinated polymeric nanoparticles for improved therapeutic efficacy. ACS Nano, 14 (6) acsnano.0c02954, 7425-7434. doi: 10.1021/acsnano.0c02954
2020
Conference Publication
Canine PET/CT imaging with 64Cu-nanomedicines
Daniel, Sarah, Houston, Zachary, Fletcher, Nicholas, Bell, Craig, Atcheson, Nicole, Al-Najjar, Aiman, Howard, Christopher, Mahler, Stephen, Straw, Rod and Thurecht, Kristofer (2020). Canine PET/CT imaging with 64Cu-nanomedicines. SNMMI Annual Meeting, Online, 11-14 July, 2020. Reston, VA, United States: Society of Nuclear Medicine.
2020
Journal Article
Oral delivery of multicompartment nanomedicines for colorectal cancer therapeutics: combining loco-regional delivery with cell-target specificity
Akhter, Dewan T., Simpson, Joshua D., Fletcher, Nicholas L., Houston, Zachary H., Fuchs, Adrian V., Bell, Craig A. and Thurecht, Kristofer J. (2020). Oral delivery of multicompartment nanomedicines for colorectal cancer therapeutics: combining loco-regional delivery with cell-target specificity. Advanced Therapeutics, 3 (2) 1900171, 1-13. doi: 10.1002/adtp.201900171
2020
Journal Article
Targeted and modular architectural polymers employing bioorthogonal chemistry for quantitative therapeutic delivery
Ediriweera, Gayathri R., Simpson, Joshua D., Fuchs, Adrian V., Venkatachalam, Taracad K., Van De Walle, Matthias, Howard, Christopher B., Mahler, Stephen M., Blinco, James P., Fletcher, Nicholas L., Houston, Zachary H., Bell, Craig A. and Thurecht, Kristofer J. (2020). Targeted and modular architectural polymers employing bioorthogonal chemistry for quantitative therapeutic delivery. Chemical Science, 11 (12), 3268-3280. doi: 10.1039/d0sc00078g
2019
Journal Article
Poly(2-oxazoline) macromonomers as building blocks for functional and biocompatible polymer architectures
Pizzi, David, Humphries, James, Morrow, Joshua P., Fletcher, Nicholas L., Bell, Craig A., Thurecht, Kristofer J. and Kempe, Kristian (2019). Poly(2-oxazoline) macromonomers as building blocks for functional and biocompatible polymer architectures. European Polymer Journal, 121 109258, 109258. doi: 10.1016/j.eurpolymj.2019.109258
Supervision
Availability
- Dr Craig Bell is:
- Available for supervision
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Supervision history
Current supervision
-
Doctor Philosophy
Development of polymeric nanoparticles for monitoring cytokine release in vivo via FRET
Associate Advisor
Other advisors: Associate Professor Idriss Blakey, Professor Kristofer Thurecht
-
Doctor Philosophy
Novel complementary diagnostics for improved therapeutics/theranostics
Associate Advisor
Other advisors: Dr Nick Fletcher, Dr Rhia Stone, Professor Kristofer Thurecht
-
Doctor Philosophy
Development of novel polymer-protein conjugates
Associate Advisor
Other advisors: Associate Professor Idriss Blakey, Professor Kristofer Thurecht
-
Doctor Philosophy
Methods for protein structure analysis using spin labelling, electron paramagnetic resonance spectroscopy and molecular modelling
Associate Advisor
Other advisors: Professor Bostjan Kobe, Dr Rhia Stone, Associate Professor Jeffrey Harmer
-
Doctor Philosophy
Development of site-specific radiopharmaceuticals using nanotechnology
Associate Advisor
Other advisors: Dr Nick Fletcher, Dr James Humphries, Professor Kristofer Thurecht
-
Doctor Philosophy
Novel complementary diagnostics for improved therapeutics/theranostics
Associate Advisor
Other advisors: Dr Nick Fletcher, Dr Rhia Stone, Professor Kristofer Thurecht
-
Doctor Philosophy
Aqueous one-pot photoinitiated polymerization-induced self-assembly (photo-PISA) to synthesize therapeutic protein loaded nanocarriers
Associate Advisor
Other advisors: Professor Kristofer Thurecht, Dr Gayathri Ediriweera
-
Doctor Philosophy
Development of novel polymer-protein conjugates
Associate Advisor
Other advisors: Associate Professor Idriss Blakey, Professor Kristofer Thurecht
-
Doctor Philosophy
Development of polymeric nanoparticles for monitoring cytokine release in vivo via FRET
Associate Advisor
Other advisors: Associate Professor Idriss Blakey, Professor Kristofer Thurecht
Completed supervision
-
2023
Doctor Philosophy
Design of pH-sensitive, polymeric nanoparticles, and their application in chemotherapeutic drug delivery
Associate Advisor
Other advisors: Dr Nick Fletcher, Professor Kristofer Thurecht
-
2023
Doctor Philosophy
Understanding Immunogenicity in Nanomedicine
Associate Advisor
Other advisors: Dr Nick Fletcher, Dr Pie Huda, Professor Kristofer Thurecht
-
2023
Doctor Philosophy
Photoacoustic Molecular Imaging in Nanomedicine: Development of a Polymeric Probe to Assess Tumour Penetration and Reassessment of the Contrast Enhancement Mechanism
Associate Advisor
Other advisors: Professor Kristofer Thurecht
-
2021
Doctor Philosophy
Self-assembled polymeric theranostics for hepatic fibrosis - An approach to non-invasive staging and targeted drug delivery
Associate Advisor
Other advisors: Professor Kristofer Thurecht
-
2021
Doctor Philosophy
Biological Interactions of Polymeric Nanomedicines & Molecular Imaging Agents
Associate Advisor
Other advisors: Dr Nick Fletcher, Professor Kristofer Thurecht
-
2020
Doctor Philosophy
Development of polymeric theranostics using bioorthogonal chemistry
Associate Advisor
Other advisors: Professor Kristofer Thurecht
-
2020
Doctor Philosophy
Design and synthesis of nanomaterials as combination therapeutics
Associate Advisor
Other advisors: Professor Kristofer Thurecht
-
2018
Doctor Philosophy
Development of novel polymeric theranostic for the treatment of colorectal cancer
Associate Advisor
Other advisors: Professor Kristofer Thurecht
Media
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