Overview
Background
I graduated with Honours in Medicine from the University of the West Indies, Jamaica, in 1992. In 1997 I relocated to the UK where I specialised in Obstetrics & Gynaecology and was admitted as a Member of the Royal College of Obstetricians & Gynaecologists in 1999. In 2012 I gained dual accreditation as a Subspecialist in Reproductive Medicine & Surgery and was admitted to the European Specialist Register. In 2012, I was appointed Senior Lecturer and Consultant in Reproductive Medicine & Surgery at University College London (UCL) and UCL Hospitals where I was the clinical lead for IVF and Recurrent Miscarriage and the scientific lead for Mammalian Oocyte Research within UCL’s Institute for Women’s Health. In January 2014 I relocated to Australia after being recruited to UNSW through the DVCR’s Strategic Priority Funding Scheme. At UNSW I jointly set up and co-directed UNSW’s first oocyte biology research lab. In January 2016, following a competitive global search, I was appointed to the fully endowed Christopher Chen Chair in Reproductive Medicine at UQ where I currently head the Christopher Chen Oocyte Research Laboratory. Since relocating to Australia I have been awarded Fellowship of the Royal Australian NZ College of Obstetricians & Gynaecologists.
In parallel with clinical activity, I have developed an internationally leading research program investigating oocyte maturation and oocyte quality. My Ph.D was awarded in 2009 from the University of Newcastle-upon-Tyne (UK) and received a Dean’s commendation. My thesis investigated the regulation of chromosome segregation in mouse and human oocytes and was funded by a WellBeing of Women Research Training Fellowship. My post-doctoral research was undertaken at UCL funded by a prestigious Wellcome Trust Clinician Scientist Fellowship ($1.2 million). At UCL, I was one of the principal investigators in the cross-faculty Mammalian Oocyte and Embryo Research Laboratory. In my first 2 years in Australia, I have secured NHMRC funding as CIA worth over $1 million.
I have placed leading papers on oocyte regulation in high impact journals such as Science, Developmental Cell, Genes & Development and Nature Cell Biology all of which have been cited by the Faculty of 1000 Experts. I have received numerous prizes and awards including the highly prestigious Medical Research Society Young Investigator Award (first and only award made to the specialty of O&G in the UK) and was the first of the UK Walport Clinical Lecturers in all specialties to attain Clinician Scientist status. I was one of the very few to have delivered the RCOG’s William Blair Bell Memorial Lecture whilst still a clinical trainee.
Availability
- Professor Hayden Homer is:
- Available for supervision
Fields of research
Qualifications
- Bachelor (Honours) of Medicine Surgery, Newcastle University
- Doctor of Philosophy, Newcastle University
- Royal Australian and New Zealand College of Obstetricians and Gynaecologists, Royal Australian and New Zealand College of Obstetricians and Gynaecologists
- Royal College of Obstetricians and Gynaecologists, Royal College of Obstetricians and Gynaecologists
Works
Search Professor Hayden Homer’s works on UQ eSpace
2024
Book Chapter
Using FRET to Define Cdk1-Dependent Ordering of Events During Exit from Second Meiotic M-Phase in Oocytes
Zhou, Chenxi, Ye, Yunan and Homer, Hayden (2024). Using FRET to Define Cdk1-Dependent Ordering of Events During Exit from Second Meiotic M-Phase in Oocytes. Methods in Molecular Biology. (pp. 99-114) New York, NY: Springer US. doi: 10.1007/978-1-0716-4236-8_9
2024
Journal Article
Fertility protection during chemotherapy treatment by boosting the NAD(P)+ metabolome
Ho, Wing-Hong Jonathan, Marinova, Maria B, Listijono, Dave R, Bertoldo, Michael J, Richani, Dulama, Kim, Lynn-Jee, Brown, Amelia, Riepsamen, Angelique H, Cabot, Safaa, Frost, Emily R, Bustamante, Sonia, Zhong, Ling, Selesniemi, Kaisa, Wong, Derek, Madawala, Romanthi, Marchante, Maria, Goss, Dale M, Li, Catherine, Araki, Toshiyuki, Livingston, David J, Turner, Nigel, Sinclair, David A, Walters, Kirsty A, Homer, Hayden A, Gilchrist, Robert B and Wu, Lindsay E (2024). Fertility protection during chemotherapy treatment by boosting the NAD(P)+ metabolome. EMBO Molecular Medicine, 16 (10), 2583-2618. doi: 10.1038/s44321-024-00119-w
2024
Journal Article
Understanding oocyte ageing
HOMER, Hayden A. (2024). Understanding oocyte ageing. Minerva Obstetrics and Gynecology, 76 (3), 284-292. doi: 10.23736/s2724-606x.24.05343-0
2024
Journal Article
A surge in cytoplasmic viscosity triggers nuclear remodeling required for Dux silencing and pre-implantation embryo development
Ye, Yunan and Homer, Hayden Anthony (2024). A surge in cytoplasmic viscosity triggers nuclear remodeling required for Dux silencing and pre-implantation embryo development. Cell Reports, 43 (3) 113917, 113917. doi: 10.1016/j.celrep.2024.113917
2023
Conference Publication
Fertility Preservation During Chemotherapy Treatment by NAD+ Repletion in Mice
Gilchrist, Robert, Ho, Wing-Hong Jonathan, Marinova, Maria B., Listijono, Dave R., Bertoldo, Michael J., Richani, Dulama, Lynn-Jee, Kim, Brown, Amelia, Riepsamen, Angelique H., Cabot, Safaa, Bustamante, Sonia, Zhong, Ling, Selesniemi, Kaisa, Wong, Derek, Goss, Dale M., Li, Catherine, Araki, Toshiyuki, Livingston, David J., Turner, Nigel, Sinclair, David A., Walters, Kirsty A., Homer, Hayden A. and Wu, Lindsay E. (2023). Fertility Preservation During Chemotherapy Treatment by NAD+ Repletion in Mice. 12th Congress Of The Asia Pacific Initiative On Reproduction, Adelaide, SA Australia, 7-10 September 2023. Singapore: World Scientific Publishing. doi: 10.1142/s2661318223742790
2023
Journal Article
Fertility treatment pathways and births for women with and without polycystic ovary syndrome—a retrospective population linked data study
Moss, Katrina M., Doust, Jenny, Copp, Tessa, Homer, Hayden and Mishra, Gita D. (2023). Fertility treatment pathways and births for women with and without polycystic ovary syndrome—a retrospective population linked data study. Fertility and Sterility, 121 (2), 314-322. doi: 10.1016/j.fertnstert.2023.11.008
2023
Journal Article
Effects of endometriosis on in vitro fertilisation – Myth or reality?
Homer, Hayden Anthony (2023). Effects of endometriosis on in vitro fertilisation – Myth or reality?. Australian and New Zealand Journal of Obstetrics and Gynaecology, 63 (1), 3-5. doi: 10.1111/ajo.13643
2022
Journal Article
Two‐step nuclear centring by competing microtubule‐ and actin‐based mechanisms in 2‐cell mouse embryos
Ye, Yunan and Homer, Hayden A. (2022). Two‐step nuclear centring by competing microtubule‐ and actin‐based mechanisms in 2‐cell mouse embryos. EMBO reports, 23 (11) e55251, 1-18. doi: 10.15252/embr.202255251
2022
Conference Publication
Fertility Awareness and Attitudes Among Women Embarking on a Career in Medicine
MOORE, Rebecca, MOORE, David, MACARTHUR, Lauren, HOMER, Hayden, CAMERON, Sarah and BELL, Nicholas (2022). Fertility Awareness and Attitudes Among Women Embarking on a Career in Medicine. Fertility Society Of Australia And New Zealand Annual Conference, Sydney, NSW Australia, 30 July–2 August 2022. Singapore: World Scientific Publishing. doi: 10.1142/s2661318222740656
2022
Journal Article
The oocyte spindle midzone pauses Cdk1 inactivation during fertilization to enable male pronuclear formation and embryo development
Zhou, Chenxi and Homer, Hayden A. (2022). The oocyte spindle midzone pauses Cdk1 inactivation during fertilization to enable male pronuclear formation and embryo development. Cell Reports, 39 (5) 110789, 110789. doi: 10.1016/j.celrep.2022.110789
2021
Journal Article
Delayed diagnosis of endometriosis disadvantages women in ART: a retrospective population linked data study
Moss, K. M., Doust, J., Homer, H., Rowlands, I. J., Hockey, R. and Mishra, G. D. (2021). Delayed diagnosis of endometriosis disadvantages women in ART: a retrospective population linked data study. Human Reproduction, 36 (12), 3074-3082. doi: 10.1093/humrep/deab216
2021
Journal Article
Isolation and in vitro culture of mouse oocytes
Greaney, Jessica, Subramanian, Goutham, Ye, Yunan and Homer, Hayden (2021). Isolation and in vitro culture of mouse oocytes. bio-protocol, 11 (15) e4104, e4104. doi: 10.21769/bioprotoc.4104
2021
Journal Article
Understanding oocyte ageing: can we influence the process as clinicians?
Homer, Hayden Anthony (2021). Understanding oocyte ageing: can we influence the process as clinicians?. Current Opinion in Obstetrics and Gynecology, 33 (3), 218-224. doi: 10.1097/GCO.0000000000000708
2021
Journal Article
Website advertising of IVF add‐ons: Does PGT‐A live up to its billing?
Homer, Hayden Anthony (2021). Website advertising of IVF add‐ons: Does PGT‐A live up to its billing?. Australian and New Zealand Journal of Obstetrics and Gynaecology, 61 (3), 328-330. doi: 10.1111/ajo.13366
2021
Journal Article
WDR62 is required for centriole duplication in spermatogenesis and manchette removal in spermiogenesis
Ho, Uda Y., Feng, Chun-Wei Allen, Yeap, Yvonne Y., Bain, Amanda L., Wei, Zhe, Shohayeb, Belal, Reichelt, Melissa E., Homer, Hayden, Khanna, Kum Kum, Bowles, Josephine and Ng, Dominic C. H. (2021). WDR62 is required for centriole duplication in spermatogenesis and manchette removal in spermiogenesis. Communications Biology, 4 (1) 645, 1-14. doi: 10.1038/s42003-021-02171-5
2021
Journal Article
Senataxin: a new guardian of the female germline important for delaying ovarian aging
Homer, Hayden A. (2021). Senataxin: a new guardian of the female germline important for delaying ovarian aging. Frontiers in Genetics, 12 647996, 1-9. doi: 10.3389/fgene.2021.647996
2020
Journal Article
Premature ovarian ageing following heterozygous loss of Senataxin
Subramanian, G. N., Lavin, M. and Homer, H. A. (2020). Premature ovarian ageing following heterozygous loss of Senataxin. Molecular Human Reproduction, 27 (2) gaaa080. doi: 10.1093/molehr/gaaa080
2020
Journal Article
Thyroid autoimmunity and IVF/ICSI outcomes in euthyroid women: a systematic review and meta-analysis
Venables, Ashley, Wong, Wilbert, Way, Mandy and Homer, Hayden Anthony (2020). Thyroid autoimmunity and IVF/ICSI outcomes in euthyroid women: a systematic review and meta-analysis. Reproductive Biology and Endocrinology, 18 (1) 120, 120. doi: 10.1186/s12958-020-00671-3
2020
Journal Article
Sirt1 sustains female fertility by slowing age‐related decline in oocyte quality required for post‐fertilization embryo development
Iljas, Juvita D., Wei, Zhe and Homer, Hayden A. (2020). Sirt1 sustains female fertility by slowing age‐related decline in oocyte quality required for post‐fertilization embryo development. Aging Cell, 19 (9) e13204, e13204. doi: 10.1111/acel.13204
2020
Journal Article
Nampt-mediated spindle sizing secures a post-anaphase increase in spindle speed required for extreme asymmetry
Wei, Zhe, Greaney, Jessica, Loh, Wei-Guo Nicholas and Homer, Hayden Anthony (2020). Nampt-mediated spindle sizing secures a post-anaphase increase in spindle speed required for extreme asymmetry. Nature Communications, 11 (1) 3393, 3393. doi: 10.1038/s41467-020-17088-6
Funding
Current funding
Past funding
Supervision
Availability
- Professor Hayden Homer is:
- Available for supervision
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Supervision history
Completed supervision
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2020
Doctor Philosophy
Role of nucleic acid binding proteins in oocyte development and female fertility
Principal Advisor
Other advisors: Honorary Professor Kum Kum Khanna
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2020
Doctor Philosophy
The in vivo roles of Sirtuin 1 and 3 in age- and obesity-related decline in female fertility
Principal Advisor
Other advisors: Professor Carlos Salomon Gallo
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2020
Doctor Philosophy
Asymmetric Cell Division in Mammalian Oocytes
Principal Advisor
Other advisors: Professor Carlos Salomon Gallo
Media
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