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Professor

Hayden Homer

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Overview

Background

I graduated with Honours in Medicine from the University of the West Indies, Jamaica, in 1992. In 1997 I relocated to the UK where I specialised in Obstetrics & Gynaecology and was admitted as a Member of the Royal College of Obstetricians & Gynaecologists in 1999. In 2012 I gained dual accreditation as a Subspecialist in Reproductive Medicine & Surgery and was admitted to the European Specialist Register. In 2012, I was appointed Senior Lecturer and Consultant in Reproductive Medicine & Surgery at University College London (UCL) and UCL Hospitals where I was the clinical lead for IVF and Recurrent Miscarriage and the scientific lead for Mammalian Oocyte Research within UCL’s Institute for Women’s Health. In January 2014 I relocated to Australia after being recruited to UNSW through the DVCR’s Strategic Priority Funding Scheme. At UNSW I jointly set up and co-directed UNSW’s first oocyte biology research lab. In January 2016, following a competitive global search, I was appointed to the fully endowed Christopher Chen Chair in Reproductive Medicine at UQ where I currently head the Christopher Chen Oocyte Research Laboratory. Since relocating to Australia I have been awarded Fellowship of the Royal Australian NZ College of Obstetricians & Gynaecologists.

In parallel with clinical activity, I have developed an internationally leading research program investigating oocyte maturation and oocyte quality. My Ph.D was awarded in 2009 from the University of Newcastle-upon-Tyne (UK) and received a Dean’s commendation. My thesis investigated the regulation of chromosome segregation in mouse and human oocytes and was funded by a WellBeing of Women Research Training Fellowship. My post-doctoral research was undertaken at UCL funded by a prestigious Wellcome Trust Clinician Scientist Fellowship ($1.2 million). At UCL, I was one of the principal investigators in the cross-faculty Mammalian Oocyte and Embryo Research Laboratory. In my first 2 years in Australia, I have secured NHMRC funding as CIA worth over $1 million.

I have placed leading papers on oocyte regulation in high impact journals such as Science, Developmental Cell, Genes & Development and Nature Cell Biology all of which have been cited by the Faculty of 1000 Experts. I have received numerous prizes and awards including the highly prestigious Medical Research Society Young Investigator Award (first and only award made to the specialty of O&G in the UK) and was the first of the UK Walport Clinical Lecturers in all specialties to attain Clinician Scientist status. I was one of the very few to have delivered the RCOG’s William Blair Bell Memorial Lecture whilst still a clinical trainee.

Availability

Professor Hayden Homer is:
Available for supervision

Qualifications

  • Bachelor (Honours) of Medicine Surgery, Newcastle University
  • Doctor of Philosophy, Newcastle University
  • Royal Australian and New Zealand College of Obstetricians and Gynaecologists, Royal Australian and New Zealand College of Obstetricians and Gynaecologists
  • Royal College of Obstetricians and Gynaecologists, Royal College of Obstetricians and Gynaecologists

Works

Search Professor Hayden Homer’s works on UQ eSpace

67 works between 1998 and 2024

1 - 20 of 67 works

2024

Journal Article

Fertility protection during chemotherapy treatment by boosting the NAD(P)+ metabolome

Ho, Wing-Hong Jonathan, Marinova, Maria B, Listijono, Dave R, Bertoldo, Michael J, Richani, Dulama, Kim, Lynn-Jee, Brown, Amelia, Riepsamen, Angelique H, Cabot, Safaa, Frost, Emily R, Bustamante, Sonia, Zhong, Ling, Selesniemi, Kaisa, Wong, Derek, Madawala, Romanthi, Marchante, Maria, Goss, Dale M, Li, Catherine, Araki, Toshiyuki, Livingston, David J, Turner, Nigel, Sinclair, David A, Walters, Kirsty A, Homer, Hayden A, Gilchrist, Robert B and Wu, Lindsay E (2024). Fertility protection during chemotherapy treatment by boosting the NAD(P)+ metabolome. EMBO Molecular Medicine. doi: 10.1038/s44321-024-00119-w

Fertility protection during chemotherapy treatment by boosting the NAD(P)+ metabolome

2024

Journal Article

A surge in cytoplasmic viscosity triggers nuclear remodeling required for Dux silencing and pre-implantation embryo development

Ye, Yunan and Homer, Hayden Anthony (2024). A surge in cytoplasmic viscosity triggers nuclear remodeling required for Dux silencing and pre-implantation embryo development. Cell Reports, 43 (3) 113917, 113917. doi: 10.1016/j.celrep.2024.113917

A surge in cytoplasmic viscosity triggers nuclear remodeling required for Dux silencing and pre-implantation embryo development

2024

Journal Article

Understanding oocyte ageing

HOMER, Hayden A. (2024). Understanding oocyte ageing. Minerva Obstetrics and Gynecology, 76 (3), 284-292. doi: 10.23736/s2724-606x.24.05343-0

Understanding oocyte ageing

2023

Conference Publication

Fertility Preservation During Chemotherapy Treatment by NAD+ Repletion in Mice

Gilchrist, Robert, Ho, Wing-Hong Jonathan, Marinova, Maria B., Listijono, Dave R., Bertoldo, Michael J., Richani, Dulama, Lynn-Jee, Kim, Brown, Amelia, Riepsamen, Angelique H., Cabot, Safaa, Bustamante, Sonia, Zhong, Ling, Selesniemi, Kaisa, Wong, Derek, Goss, Dale M., Li, Catherine, Araki, Toshiyuki, Livingston, David J., Turner, Nigel, Sinclair, David A., Walters, Kirsty A., Homer, Hayden A. and Wu, Lindsay E. (2023). Fertility Preservation During Chemotherapy Treatment by NAD+ Repletion in Mice. 12th Congress Of The Asia Pacific Initiative On Reproduction, Adelaide, SA Australia, 7-10 September 2023. Singapore: World Scientific Publishing. doi: 10.1142/s2661318223742790

Fertility Preservation During Chemotherapy Treatment by NAD+ Repletion in Mice

2023

Journal Article

Fertility treatment pathways and births for women with and without polycystic ovary syndrome—a retrospective population linked data study

Moss, Katrina M., Doust, Jenny, Copp, Tessa, Homer, Hayden and Mishra, Gita D. (2023). Fertility treatment pathways and births for women with and without polycystic ovary syndrome—a retrospective population linked data study. Fertility and Sterility, 121 (2), 314-322. doi: 10.1016/j.fertnstert.2023.11.008

Fertility treatment pathways and births for women with and without polycystic ovary syndrome—a retrospective population linked data study

2023

Journal Article

Effects of endometriosis on in vitro fertilisation – Myth or reality?

Homer, Hayden Anthony (2023). Effects of endometriosis on in vitro fertilisation – Myth or reality?. Australian and New Zealand Journal of Obstetrics and Gynaecology, 63 (1), 3-5. doi: 10.1111/ajo.13643

Effects of endometriosis on in vitro fertilisation – Myth or reality?

2022

Journal Article

Two‐step nuclear centring by competing microtubule‐ and actin‐based mechanisms in 2‐cell mouse embryos

Ye, Yunan and Homer, Hayden A. (2022). Two‐step nuclear centring by competing microtubule‐ and actin‐based mechanisms in 2‐cell mouse embryos. EMBO reports, 23 (11) e55251, 1-18. doi: 10.15252/embr.202255251

Two‐step nuclear centring by competing microtubule‐ and actin‐based mechanisms in 2‐cell mouse embryos

2022

Conference Publication

Fertility Awareness and Attitudes Among Women Embarking on a Career in Medicine

MOORE, Rebecca, MOORE, David, MACARTHUR, Lauren, HOMER, Hayden, CAMERON, Sarah and BELL, Nicholas (2022). Fertility Awareness and Attitudes Among Women Embarking on a Career in Medicine. Fertility Society Of Australia And New Zealand Annual Conference, Sydney, NSW Australia, 30 July–2 August 2022. Singapore: World Scientific Publishing. doi: 10.1142/s2661318222740656

Fertility Awareness and Attitudes Among Women Embarking on a Career in Medicine

2022

Journal Article

The oocyte spindle midzone pauses Cdk1 inactivation during fertilization to enable male pronuclear formation and embryo development

Zhou, Chenxi and Homer, Hayden A. (2022). The oocyte spindle midzone pauses Cdk1 inactivation during fertilization to enable male pronuclear formation and embryo development. Cell Reports, 39 (5) 110789, 110789. doi: 10.1016/j.celrep.2022.110789

The oocyte spindle midzone pauses Cdk1 inactivation during fertilization to enable male pronuclear formation and embryo development

2021

Journal Article

Delayed diagnosis of endometriosis disadvantages women in ART: a retrospective population linked data study

Moss, K. M., Doust, J., Homer, H., Rowlands, I. J., Hockey, R. and Mishra, G. D. (2021). Delayed diagnosis of endometriosis disadvantages women in ART: a retrospective population linked data study. Human Reproduction, 36 (12), 3074-3082. doi: 10.1093/humrep/deab216

Delayed diagnosis of endometriosis disadvantages women in ART: a retrospective population linked data study

2021

Journal Article

Isolation and in vitro culture of mouse oocytes

Greaney, Jessica, Subramanian, Goutham, Ye, Yunan and Homer, Hayden (2021). Isolation and in vitro culture of mouse oocytes. bio-protocol, 11 (15) e4104, e4104. doi: 10.21769/bioprotoc.4104

Isolation and in vitro culture of mouse oocytes

2021

Journal Article

Understanding oocyte ageing: can we influence the process as clinicians?

Homer, Hayden Anthony (2021). Understanding oocyte ageing: can we influence the process as clinicians?. Current Opinion in Obstetrics and Gynecology, 33 (3), 218-224. doi: 10.1097/GCO.0000000000000708

Understanding oocyte ageing: can we influence the process as clinicians?

2021

Journal Article

Website advertising of IVF add‐ons: Does PGT‐A live up to its billing?

Homer, Hayden Anthony (2021). Website advertising of IVF add‐ons: Does PGT‐A live up to its billing?. Australian and New Zealand Journal of Obstetrics and Gynaecology, 61 (3), 328-330. doi: 10.1111/ajo.13366

Website advertising of IVF add‐ons: Does PGT‐A live up to its billing?

2021

Journal Article

WDR62 is required for centriole duplication in spermatogenesis and manchette removal in spermiogenesis

Ho, Uda Y., Feng, Chun-Wei Allen, Yeap, Yvonne Y., Bain, Amanda L., Wei, Zhe, Shohayeb, Belal, Reichelt, Melissa E., Homer, Hayden, Khanna, Kum Kum, Bowles, Josephine and Ng, Dominic C. H. (2021). WDR62 is required for centriole duplication in spermatogenesis and manchette removal in spermiogenesis. Communications Biology, 4 (1) 645, 1-14. doi: 10.1038/s42003-021-02171-5

WDR62 is required for centriole duplication in spermatogenesis and manchette removal in spermiogenesis

2021

Journal Article

Senataxin: a new guardian of the female germline important for delaying ovarian aging

Homer, Hayden A. (2021). Senataxin: a new guardian of the female germline important for delaying ovarian aging. Frontiers in Genetics, 12 647996, 1-9. doi: 10.3389/fgene.2021.647996

Senataxin: a new guardian of the female germline important for delaying ovarian aging

2020

Journal Article

Premature ovarian ageing following heterozygous loss of Senataxin

Subramanian, G. N., Lavin, M. and Homer, H. A. (2020). Premature ovarian ageing following heterozygous loss of Senataxin. Molecular Human Reproduction, 27 (2) gaaa080. doi: 10.1093/molehr/gaaa080

Premature ovarian ageing following heterozygous loss of Senataxin

2020

Journal Article

Thyroid autoimmunity and IVF/ICSI outcomes in euthyroid women: a systematic review and meta-analysis

Venables, Ashley, Wong, Wilbert, Way, Mandy and Homer, Hayden Anthony (2020). Thyroid autoimmunity and IVF/ICSI outcomes in euthyroid women: a systematic review and meta-analysis. Reproductive Biology and Endocrinology, 18 (1) 120, 120. doi: 10.1186/s12958-020-00671-3

Thyroid autoimmunity and IVF/ICSI outcomes in euthyroid women: a systematic review and meta-analysis

2020

Journal Article

Sirt1 sustains female fertility by slowing age‐related decline in oocyte quality required for post‐fertilization embryo development

Iljas, Juvita D., Wei, Zhe and Homer, Hayden A. (2020). Sirt1 sustains female fertility by slowing age‐related decline in oocyte quality required for post‐fertilization embryo development. Aging Cell, 19 (9) e13204, e13204. doi: 10.1111/acel.13204

Sirt1 sustains female fertility by slowing age‐related decline in oocyte quality required for post‐fertilization embryo development

2020

Journal Article

Nampt-mediated spindle sizing secures a post-anaphase increase in spindle speed required for extreme asymmetry

Wei, Zhe, Greaney, Jessica, Loh, Wei-Guo Nicholas and Homer, Hayden Anthony (2020). Nampt-mediated spindle sizing secures a post-anaphase increase in spindle speed required for extreme asymmetry. Nature Communications, 11 (1) 3393, 3393. doi: 10.1038/s41467-020-17088-6

Nampt-mediated spindle sizing secures a post-anaphase increase in spindle speed required for extreme asymmetry

2020

Journal Article

The 2019 PGDIS position statement on transfer of mosaic embryos within a context of new information on PGT-A

Gleicher, N., Albertini, D. F., Barad, D. H., Homer, H., Modi, D., Murtinger, M., Patrizio, P., Orvieto, R., Takahashi, S., Weghofer, A., Ziebe, S., Noyes, N. and for the International Do No Harm Group in IVF (IDNHG-IVF) (2020). The 2019 PGDIS position statement on transfer of mosaic embryos within a context of new information on PGT-A. Reproductive Biology and Endocrinology, 18 (1) 57. doi: 10.1186/s12958-020-00616-w

The 2019 PGDIS position statement on transfer of mosaic embryos within a context of new information on PGT-A

Funding

Current funding

  • 2023 - 2026
    A novel approach to reducing the psychosocial burden of infertility treatment
    NHMRC IDEAS Grants
    Open grant
  • 2023 - 2025
    Characterization and validation of a new mouse model of spontaneous endometriosis to implement translation of basic research to the clinic
    United States Congressionally Directed Medical Research Programs - Peer Reviewed Medical Research Program
    Open grant

Past funding

  • 2017 - 2018
    Chlamydia infiection in the ovary: effects on fertility in female koalas
    Annandale Bequest
    Open grant
  • 2017 - 2021
    Nicotinamide adenine dinucleotide (NAD+)-raising agents for improving oocyte quality
    NHMRC Development Grant
    Open grant
  • 2016 - 2018
    Female reproductive health preservation by Nictotinamide Adenine Dinucleotide (NAD+) and Sirtuin2 (SIRT2)
    NHMRC Project Grant
    Open grant
  • 2015 - 2018
    A BubR1-centred network for non-invasively measuring human oocyte quality
    NHMRC Project Grant
    Open grant

Supervision

Availability

Professor Hayden Homer is:
Available for supervision

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Supervision history

Completed supervision

Media

Enquiries

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