Overview
Background
Professor Roger Wepf is the Director of the Centre for Microscopy and Microanalysis (CMM) and leads the UQ node of Microscopy Australia. His career spans decades at the forefront of high-resolution imaging in electron microscopy, structural biology, and advanced analytical workflows of material science, with previous leadership roles at ETH Zurich and in the EMBL Heidelberg Physical Instrumentation R&D group. At UQ, he has driven the development of multimodal and correlative microscopy approaches, integrating light microscopy, electron microscopy, X-ray fluorescence microscopy, imaging mass spectrometry and advanced data management. Professor Wepf has been instrumental in developing cryo sample preparation tools and correlative workflows that are now used globally and marketed by well-known suppliers in the electron microscopy field. He also established with NewSpec/Hitachi the Inspire outreach program in QLD, delivering a desktop SEM to local schools to train the next generation of curious scientific minds. He has played a key role in building NRICH’s capabilities for large-scale mineral, biological, and materials characterisation, combining state-of-the-art instrumentation with innovative workflows and data integration pipelines that adhere to FAIR/FAIR-CARE principles.
Professor Wepf’s research bridges academic and industry needs, from localisation of biomolecules at the nanoscale to the characterisation of beam- and environment-sensitive materials critical for quantum technologies, catalysis, and battery development. His leadership has fostered partnerships with global instrumentation companies and industry collaborators to co-develop new imaging hardware, detectors, and workflows. He is a founding member of two scientific journals, most recently Methods in Microscopy with De Gruyter, a community-focused open access journal advancing method development and dissemination in the microscopy field. He has also initiated strategic programs such as the Pitschi data repository and multimodal segmentation projects, enabling the Australian research community to manage, share, and analyse large datasets at scale. Professor Wepf’s commitment to mentoring and training ensures that the next generation of scientists are skilled in applying advanced microscopy to solve problems in energy, health, minerals, and materials science. He also established with NewSpec/ Hitachi the Inpsire outreach program in QLD delivering a desktop SEM to local schools to train next generation of curious scientific minds
Availability
- Professor Roger Wepf is:
- Available for supervision
Qualifications
- Doctoral Diploma of Science (Advanced), Swiss Federal Institute of Technology ETH Zürich
Works
Search Professor Roger Wepf’s works on UQ eSpace
2011
Journal Article
Measuring single-nanoparticle wetting properties by freeze-fracture shadow-casting cryo-scanning electron microscopy
Isa, Lucio, Lucas, Falk, Wepf, Roger and Reimhult, Erik (2011). Measuring single-nanoparticle wetting properties by freeze-fracture shadow-casting cryo-scanning electron microscopy. Nature Communications, 2 (1) 438. doi: 10.1038/ncomms1441
2011
Journal Article
Three-dimensional reconstruction of Heterocapsa circularisquama RNA virus by electron cryo-microscopy
Miller, Jennifer L., Woodward, Jeremy, Chen, Shaoxia, Jaffer, Mohammed, Weber, Brandon, Nagasaki, Keizo, Tomaru, Yuji, Wepf, Roger, Roseman, Alan, Varsani, Arvind and Sewell, Trevor (2011). Three-dimensional reconstruction of Heterocapsa circularisquama RNA virus by electron cryo-microscopy. Journal of General Virology, 92 (8), 1960-1970. doi: 10.1099/vir.0.031211-0
2011
Journal Article
Serial FIB/SEM imaging for quantitative 3D assessment of the osteocyte lacuno-canalicular network
Schneider, Philipp, Meier, Matias, Wepf, Roger and Müller, Ralph (2011). Serial FIB/SEM imaging for quantitative 3D assessment of the osteocyte lacuno-canalicular network. Bone, 49 (2), 304-311. doi: 10.1016/j.bone.2011.04.005
2011
Journal Article
Minimization of amorphous layer in Ar+ ion milling for UHR-EM
Süess, M. J., Mueller, E. and Wepf, R. (2011). Minimization of amorphous layer in Ar+ ion milling for UHR-EM. Ultramicroscopy, 111 (8), 1224-1232. doi: 10.1016/j.ultramic.2011.03.004
2011
Journal Article
3D geometry and topology of pore pathways in Opalinus clay: implications for mass transport
Keller, Lukas M., Holzer, Lorenz, Wepf, Roger and Gasser, Philippe (2011). 3D geometry and topology of pore pathways in Opalinus clay: implications for mass transport. Applied Clay Science, 52 (1-2), 85-95. doi: 10.1016/j.clay.2011.02.003
2011
Journal Article
Focussed ion beam nanotomography reveals the 3D morphology of different solid phases in hardened cement pastes
Trtik, P., Münch, B., Gasser, P., Leemann, A., Loser, R., Wepf, R. and Lura, P. (2011). Focussed ion beam nanotomography reveals the 3D morphology of different solid phases in hardened cement pastes. Journal of Microscopy, 241 (3), 234-242. doi: 10.1111/j.1365-2818.2010.03433.x
2011
Journal Article
Characterization of catalysts in an aberration-corrected scanning transmission electron microscope
Krumeich, Frank, Müller, Elisabeth, Wepf, Roger A. and Nesper, Reinhard (2011). Characterization of catalysts in an aberration-corrected scanning transmission electron microscope. Journal of Physical Chemistry C, 115 (4), 1080-1083. doi: 10.1021/jp105997h
2011
Journal Article
The largest synthetic structure with molecular precision: towards a molecular object
Zhang, Baozhong, Wepf, Roger, Fischer, Karl, Schmidt, Manfred, Besse, Sébastien, Lindner, Peter, King, Benjamin T., Sigel, Reinhard, Schurtenberger, Peter, Talmon, Yeshayahu, Ding, Yi, Kröger, Martin, Halperin, Avraham and Schlüter, A. Dieter (2011). The largest synthetic structure with molecular precision: towards a molecular object. Angewandte Chemie - International Edition, 50 (3), 737-740. doi: 10.1002/anie.201005164
2010
Journal Article
Towards quantitative 3D imaging of the osteocyte lacuno-canalicular network
Schneider, Philipp, Meier, Matias, Wepf, Roger and Müller, Ralph (2010). Towards quantitative 3D imaging of the osteocyte lacuno-canalicular network. Bone, 47 (5), 848-858. doi: 10.1016/j.bone.2010.07.026
2010
Journal Article
Ptychographic X-ray computed tomography at the nanoscale
Dierolf, Martin, Menzel, Andreas, Thibault, Pierre, Schneider, Philipp, Kewish, Cameron M., Wepf, Roger, Bunk, Oliver and Pfeiffer, Franz (2010). Ptychographic X-ray computed tomography at the nanoscale. Nature, 467 (7314), 436-439. doi: 10.1038/nature09419
2010
Journal Article
3D-microstructure analysis of hydrated bentonite with cryo-stabilized pore water
Holzer, L., Münch, B., Rizzi, M., Wepf, R., Marschall, P. and Graule, T. (2010). 3D-microstructure analysis of hydrated bentonite with cryo-stabilized pore water. Applied Clay Science, 47 (3-4), 330-342. doi: 10.1016/j.clay.2009.11.045
2009
Journal Article
Three-dimensional reconstruction of biological macromolecular complexes from in-lens scanning electron micrographs
Woodward, J. D., Wepf, R. and Sewell, B. T. (2009). Three-dimensional reconstruction of biological macromolecular complexes from in-lens scanning electron micrographs. Journal of Microscopy, 234 (3), 287-292. doi: 10.1111/j.1365-2818.2009.03168.x
2008
Journal Article
Assessing the risk of skin damage due to femtosecond laser irradiation
Fischer, Frank, Volkmer, Beate, Puschmann, Stefan, Greinert, Rüdiger, Breitbart, Eckhard, Kiefer, Jürgen and Wepf, Roger (2008). Assessing the risk of skin damage due to femtosecond laser irradiation. Journal of Biophotonics, 1 (6), 470-477. doi: 10.1002/jbio.200810050
2008
Journal Article
Risk estimation of skin damage due to ultrashort pulsed, focused near-infrared laser irradiation at 800nm
Fischer, Frank, Volkmer, Beate, Puschmann, Stefan, Greinert, Ruediger, Breitbart, Wolfgang, Kiefer, Juergen and Wepf, Roger (2008). Risk estimation of skin damage due to ultrashort pulsed, focused near-infrared laser irradiation at 800nm. Journal of Biomedical Optics, 13 (4) 041320, 041320. doi: 10.1117/1.2960016
2008
Journal Article
Influence of pH on colloidal properties and surface activity of polyglycerol fatty acid ester vesicles
Duerr-Auster, N., Eisele, T., Wepf, R., Gunde, R. and Windhab, E. J. (2008). Influence of pH on colloidal properties and surface activity of polyglycerol fatty acid ester vesicles. Journal of Colloid and Interface Science, 327 (2), 446-450. doi: 10.1016/j.jcis.2008.08.047
2008
Journal Article
Visualizing nuclei in skin cryosections: Viable options to 4′6-diamidino-2-phenylindol for confocal laser microscopy
Gläser, K., Wilke, K., Wepf, R. and Biel, Stefan (2008). Visualizing nuclei in skin cryosections: Viable options to 4′6-diamidino-2-phenylindol for confocal laser microscopy. Skin Research and Technology, 14 (3), 324-326. doi: 10.1111/j.1600-0846.2008.00298.x
2008
Conference Publication
Life-like physical fixation of large samples for correlative microscopy
Rensing, K., Wölfel, M., Droste, M. S., Lucas, F. and Wepf, R. (2008). Life-like physical fixation of large samples for correlative microscopy. doi: 10.1017/S1431927608087758
2008
Journal Article
Combined use of confocal laser scanning microscopy and transmission electron microscopy for visualization of identical cells processed by cryotechniques: (Protoplasma (2003) 222, (129-137))
Wepf, Roger, Beese, Marita and Krupinska, Karin (2008). Combined use of confocal laser scanning microscopy and transmission electron microscopy for visualization of identical cells processed by cryotechniques: (Protoplasma (2003) 222, (129-137)). Protoplasma, 232 (3-4), 267-269. doi: 10.1007/s00709-008-0294-y
2008
Journal Article
A strategy for correlative microscopy of large skin samples: Towards a holistic view of axillary skin complexity
Wilke, Katrin, Wick, Katrin, Keil, Frerich J., Wittern, Klaus-Peter, Wepf, Roger and Biel, Stefan S. (2008). A strategy for correlative microscopy of large skin samples: Towards a holistic view of axillary skin complexity. Experimental Dermatology, 17 (1), 73-80. doi: 10.1111/j.1600-0625.2007.00635.x
2007
Journal Article
Cryo-FIB-nanotomography for quantitative analysis of particle structures in cement suspensions
Holzer, L., Gasser, Ph, Kaech, A., Wegmann, M., Zingg, A., Wepf, R. and Muench, B. (2007). Cryo-FIB-nanotomography for quantitative analysis of particle structures in cement suspensions. Journal of Microscopy, 227 (3), 216-228. doi: 10.1111/j.1365-2818.2007.01804.x
Funding
Current funding
Supervision
Availability
- Professor Roger Wepf is:
- Available for supervision
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Supervision history
Current supervision
-
Doctor Philosophy
Development of topical delivery system (TDS): Role of intrinsic and extrinsic factors on performance
Associate Advisor
Other advisors: Associate Professor Yousuf Mohammed
Media
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