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Professor Roger Wepf
Professor

Roger Wepf

Email: 
Phone: 
+61 7 334 63966

Overview

Background

Professor Roger Wepf is the Director of the Centre for Microscopy and Microanalysis (CMM) and leads the UQ node of Microscopy Australia. His career spans decades at the forefront of high-resolution imaging in electron microscopy, structural biology, and advanced analytical workflows of material science, with previous leadership roles at ETH Zurich and in the EMBL Heidelberg Physical Instrumentation R&D group. At UQ, he has driven the development of multimodal and correlative microscopy approaches, integrating light microscopy, electron microscopy, X-ray fluorescence microscopy, imaging mass spectrometry and advanced data management. Professor Wepf has been instrumental in developing cryo sample preparation tools and correlative workflows that are now used globally and marketed by well-known suppliers in the electron microscopy field. He also established with NewSpec/Hitachi the Inspire outreach program in QLD, delivering a desktop SEM to local schools to train the next generation of curious scientific minds. He has played a key role in building NRICH’s capabilities for large-scale mineral, biological, and materials characterisation, combining state-of-the-art instrumentation with innovative workflows and data integration pipelines that adhere to FAIR/FAIR-CARE principles.

Professor Wepf’s research bridges academic and industry needs, from localisation of biomolecules at the nanoscale to the characterisation of beam- and environment-sensitive materials critical for quantum technologies, catalysis, and battery development. His leadership has fostered partnerships with global instrumentation companies and industry collaborators to co-develop new imaging hardware, detectors, and workflows. He is a founding member of two scientific journals, most recently Methods in Microscopy with De Gruyter, a community-focused open access journal advancing method development and dissemination in the microscopy field. He has also initiated strategic programs such as the Pitschi data repository and multimodal segmentation projects, enabling the Australian research community to manage, share, and analyse large datasets at scale. Professor Wepf’s commitment to mentoring and training ensures that the next generation of scientists are skilled in applying advanced microscopy to solve problems in energy, health, minerals, and materials science. He also established with NewSpec/ Hitachi the Inpsire outreach program in QLD delivering a desktop SEM to local schools to train next generation of curious scientific minds

Availability

Professor Roger Wepf is:
Available for supervision

Qualifications

  • Doctoral Diploma of Science (Advanced), Swiss Federal Institute of Technology ETH Zürich

Works

Search Professor Roger Wepf’s works on UQ eSpace

111 works between 1989 and 2025

101 - 111 of 111 works

1997

Journal Article

TEM moire patterns explain STM images of bacteriophage T5 tails

Guénebaut, V., Maaloum, M., Bonhivers, M., Wepf, R., Leonard, K. and Hörber, J. K.H. (1997). TEM moire patterns explain STM images of bacteriophage T5 tails. Ultramicroscopy, 69 (2), 129-137. doi: 10.1016/S0304-3991(97)00042-9

TEM moire patterns explain STM images of bacteriophage T5 tails

1996

Journal Article

Roles for Rac1 and Cdc42 in planar polarization and hair outgrowth in the wing of Drosophila

Eaton, Suzanne, Wepf, Roger and Simons, Kai (1996). Roles for Rac1 and Cdc42 in planar polarization and hair outgrowth in the wing of Drosophila. Journal of Cell Biology, 135 (5), 1277-1289. doi: 10.1083/jcb.135.5.1277

Roles for Rac1 and Cdc42 in planar polarization and hair outgrowth in the wing of Drosophila

1996

Journal Article

Rab8 promotes polarized membrane transport through reorganization of actin and microtubules in fibroblasts

Peränen, Johan, Auvinen, Petri, Virta, Hilkka, Wepf, Roger and Simons, Kai (1996). Rab8 promotes polarized membrane transport through reorganization of actin and microtubules in fibroblasts. Journal of Cell Biology, 135 (1), 153-167. doi: 10.1083/jcb.135.1.153

Rab8 promotes polarized membrane transport through reorganization of actin and microtubules in fibroblasts

1996

Journal Article

Nic96p is required for nuclear pore formation and functionally interacts with a novel nucleoporin, Nup188p

Zabel, Ulrike, Doye, Valérie, Tekotte, Hildegard, Wepf, Roger, Grandi, Paola and Hurt, Eduard C. (1996). Nic96p is required for nuclear pore formation and functionally interacts with a novel nucleoporin, Nup188p. Journal of Cell Biology, 133 (6), 1141-1152. doi: 10.1083/jcb.133.6.1141

Nic96p is required for nuclear pore formation and functionally interacts with a novel nucleoporin, Nup188p

1995

Journal Article

The core of the mammalian centriole contains γ-tubulin

Fuller, Stephen D., Gowen, Brent E., Reinsch, Sigrid, Sawyer, Alan, Buendia, Brigitte, Wepf, Roger and Karsenti, Eric (1995). The core of the mammalian centriole contains γ-tubulin. Current Biology, 5 (12), 1384-1393. doi: 10.1016/S0960-9822(95)00276-4

The core of the mammalian centriole contains γ-tubulin

1995

Journal Article

The Drosophila orphan nuclear receptor seven-up requires the Ras pathway for its function in photoreceptor determination

Begemann, G., Michon, A. M., v.d. Voorn, L., Wepf, R. and Mlodzik, M. (1995). The Drosophila orphan nuclear receptor seven-up requires the Ras pathway for its function in photoreceptor determination. Development, 121 (1), 225-235.

The Drosophila orphan nuclear receptor seven-up requires the Ras pathway for its function in photoreceptor determination

1994

Journal Article

A novel nuclear pore protein Nup133p with distinct roles in poly(A)+ RNA transport and nuclear pore distribution

Doye, V., Wepf, R. and Hurt, E. C. (1994). A novel nuclear pore protein Nup133p with distinct roles in poly(A)+ RNA transport and nuclear pore distribution. EMBO Journal, 13 (24), 6062-6075.

A novel nuclear pore protein Nup133p with distinct roles in poly(A)+ RNA transport and nuclear pore distribution

1994

Journal Article

Electron spectroscopy and atomic force microscopy studies of DNA adsorption on mica

Rabke, C. E., Wenzler, L. A., Beebe Jr., T. P., Lindsay, S. M., Wepf, R., Thundat, T., McCarley, R. L., Vesenka, J. and Johari, O. (1994). Electron spectroscopy and atomic force microscopy studies of DNA adsorption on mica. Scanning Microscopy, 8 (3), 471-480.

Electron spectroscopy and atomic force microscopy studies of DNA adsorption on mica

1994

Conference Publication

High-resolution SEM of biological macromolecular complexes

Wepf, R., Aebi, U., Bremer, A., Haider, M., Tittmann, P., Zach, J. and Gross, H. (1994). High-resolution SEM of biological macromolecular complexes.

High-resolution SEM of biological macromolecular complexes

1991

Journal Article

Platinum/iridium/carbon: a high‐resolution shadowing material for TEM, STM and SEM of biological macromolecular structures

Wepf, Roger, Amrein, Matthias, Bürkli, Urs and Gross, Heinz (1991). Platinum/iridium/carbon: a high‐resolution shadowing material for TEM, STM and SEM of biological macromolecular structures. Journal of Microscopy, 163 (1), 51-64. doi: 10.1111/j.1365-2818.1991.tb03159.x

Platinum/iridium/carbon: a high‐resolution shadowing material for TEM, STM and SEM of biological macromolecular structures

1989

Journal Article

STM of freeze-dried and PtIrC-coated bacteriophage T4 polyheads

Aivirein, Matthias, Dürr, Roland, Winkler, Hanspeter, Travaglini, Giorgio, Wepf, Roger and Gross, Heinz (1989). STM of freeze-dried and PtIrC-coated bacteriophage T4 polyheads. Journal of Ultrastructure Research and Molecular Structure Research, 102 (2), 170-177. doi: 10.1016/0889-1605(89)90054-2

STM of freeze-dried and PtIrC-coated bacteriophage T4 polyheads

Funding

Current funding

  • 2026 - 2030
    Advanced Flow Battery for Synergetic Carbon Capture and Energy Storage
    ARC Discovery Projects
    Open grant
  • 2024 - 2027
    Structure-guided optimisation of light-driven microalgae cell factories
    ARC Discovery Projects
    Open grant
  • 2023 - 2028
    Microscopy Australia - Australian Microscopy and Microanalysis Research Facility (AMMRF) - NCRIS22 (administered by the University of Sydney)
    University of Sydney
    Open grant

Past funding

  • 2024 - 2025
    Advanced Surface Characterisation for Minerals (RTCM Trailblazer project administered by Curtain University)
    Curtin University
    Open grant
  • 2023 - 2024
    Nanocrystal Electron Diffraction Facility
    ARC Linkage Infrastructure, Equipment and Facilities
    Open grant
  • 2021 - 2023
    A customised triple-beam microscope for precise fabricating/characterising
    ARC Linkage Infrastructure, Equipment and Facilities
    Open grant
  • 2020 - 2024
    CMM Queensland Government NCRIS Co-investment Support 2019-2023 (RICF)
    University of Sydney
    Open grant
  • 2019 - 2020
    A correlative cryo-microscopy suite (ARC LIEF project administered by USYD)
    University of Sydney
    Open grant
  • 2019
    Imaging Mass Spectrometry at Higher Mass Resolution
    UQ Research Facilities Infrastructure Grants
    Open grant
  • 2018 - 2020
    The Characterisation Data Enhanced Virtual Laboratory (ANDS NCRIS administered by Monash University)
    Monash University
    Open grant
  • 2018 - 2019
    Automated high resolution & high contrast cryoTEM for 3D structural biology
    ARC Linkage Infrastructure, Equipment and Facilities
    Open grant
  • 2018 - 2019
    Advanced micro-X-ray Fluorescence facility for biological, medical, materials science and geochemistry
    UQ Major Equipment and Infrastructure
    Open grant
  • 2018
    Cryoelectron Microscopy Platform for Cellular Structural Biology
    UQ Major Equipment and Infrastructure
    Open grant
  • 2018 - 2019
    Data storage infrastructure
    UQ Research Facilities Infrastructure Grants
    Open grant
  • 2013 - 2024
    Australian Microscopy and Microanalysis Research Facility (AMMRF) - NCRIS 2013/2015/2016-17/2017-19/2019-22 (administered by the University of Sydney)
    University of Sydney
    Open grant

Supervision

Availability

Professor Roger Wepf is:
Available for supervision

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Supervision history

Current supervision

  • Doctor Philosophy

    Development of topical delivery system (TDS): Role of intrinsic and extrinsic factors on performance

    Associate Advisor

    Other advisors: Associate Professor Yousuf Mohammed

Media

Enquiries

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