Overview
Background
Professor Roger Wepf is the Director of the Centre for Microscopy and Microanalysis (CMM) and leads the UQ node of Microscopy Australia. His career spans decades at the forefront of high-resolution imaging in electron microscopy, structural biology, and advanced analytical workflows of material science, with previous leadership roles at ETH Zurich and in the EMBL Heidelberg Physical Instrumentation R&D group. At UQ, he has driven the development of multimodal and correlative microscopy approaches, integrating light microscopy, electron microscopy, X-ray fluorescence microscopy, imaging mass spectrometry and advanced data management. Professor Wepf has been instrumental in developing cryo sample preparation tools and correlative workflows that are now used globally and marketed by well-known suppliers in the electron microscopy field. He also established with NewSpec/Hitachi the Inspire outreach program in QLD, delivering a desktop SEM to local schools to train the next generation of curious scientific minds. He has played a key role in building NRICH’s capabilities for large-scale mineral, biological, and materials characterisation, combining state-of-the-art instrumentation with innovative workflows and data integration pipelines that adhere to FAIR/FAIR-CARE principles.
Professor Wepf’s research bridges academic and industry needs, from localisation of biomolecules at the nanoscale to the characterisation of beam- and environment-sensitive materials critical for quantum technologies, catalysis, and battery development. His leadership has fostered partnerships with global instrumentation companies and industry collaborators to co-develop new imaging hardware, detectors, and workflows. He is a founding member of two scientific journals, most recently Methods in Microscopy with De Gruyter, a community-focused open access journal advancing method development and dissemination in the microscopy field. He has also initiated strategic programs such as the Pitschi data repository and multimodal segmentation projects, enabling the Australian research community to manage, share, and analyse large datasets at scale. Professor Wepf’s commitment to mentoring and training ensures that the next generation of scientists are skilled in applying advanced microscopy to solve problems in energy, health, minerals, and materials science. He also established with NewSpec/ Hitachi the Inpsire outreach program in QLD delivering a desktop SEM to local schools to train next generation of curious scientific minds
Availability
- Professor Roger Wepf is:
- Available for supervision
Qualifications
- Doctoral Diploma of Science (Advanced), Swiss Federal Institute of Technology ETH Zürich
Works
Search Professor Roger Wepf’s works on UQ eSpace
1997
Journal Article
TEM moire patterns explain STM images of bacteriophage T5 tails
Guénebaut, V., Maaloum, M., Bonhivers, M., Wepf, R., Leonard, K. and Hörber, J. K.H. (1997). TEM moire patterns explain STM images of bacteriophage T5 tails. Ultramicroscopy, 69 (2), 129-137. doi: 10.1016/S0304-3991(97)00042-9
1996
Journal Article
Roles for Rac1 and Cdc42 in planar polarization and hair outgrowth in the wing of Drosophila
Eaton, Suzanne, Wepf, Roger and Simons, Kai (1996). Roles for Rac1 and Cdc42 in planar polarization and hair outgrowth in the wing of Drosophila. Journal of Cell Biology, 135 (5), 1277-1289. doi: 10.1083/jcb.135.5.1277
1996
Journal Article
Rab8 promotes polarized membrane transport through reorganization of actin and microtubules in fibroblasts
Peränen, Johan, Auvinen, Petri, Virta, Hilkka, Wepf, Roger and Simons, Kai (1996). Rab8 promotes polarized membrane transport through reorganization of actin and microtubules in fibroblasts. Journal of Cell Biology, 135 (1), 153-167. doi: 10.1083/jcb.135.1.153
1996
Journal Article
Nic96p is required for nuclear pore formation and functionally interacts with a novel nucleoporin, Nup188p
Zabel, Ulrike, Doye, Valérie, Tekotte, Hildegard, Wepf, Roger, Grandi, Paola and Hurt, Eduard C. (1996). Nic96p is required for nuclear pore formation and functionally interacts with a novel nucleoporin, Nup188p. Journal of Cell Biology, 133 (6), 1141-1152. doi: 10.1083/jcb.133.6.1141
1995
Journal Article
The core of the mammalian centriole contains γ-tubulin
Fuller, Stephen D., Gowen, Brent E., Reinsch, Sigrid, Sawyer, Alan, Buendia, Brigitte, Wepf, Roger and Karsenti, Eric (1995). The core of the mammalian centriole contains γ-tubulin. Current Biology, 5 (12), 1384-1393. doi: 10.1016/S0960-9822(95)00276-4
1995
Journal Article
The Drosophila orphan nuclear receptor seven-up requires the Ras pathway for its function in photoreceptor determination
Begemann, G., Michon, A. M., v.d. Voorn, L., Wepf, R. and Mlodzik, M. (1995). The Drosophila orphan nuclear receptor seven-up requires the Ras pathway for its function in photoreceptor determination. Development, 121 (1), 225-235.
1994
Journal Article
A novel nuclear pore protein Nup133p with distinct roles in poly(A)+ RNA transport and nuclear pore distribution
Doye, V., Wepf, R. and Hurt, E. C. (1994). A novel nuclear pore protein Nup133p with distinct roles in poly(A)+ RNA transport and nuclear pore distribution. EMBO Journal, 13 (24), 6062-6075.
1994
Journal Article
Electron spectroscopy and atomic force microscopy studies of DNA adsorption on mica
Rabke, C. E., Wenzler, L. A., Beebe Jr., T. P., Lindsay, S. M., Wepf, R., Thundat, T., McCarley, R. L., Vesenka, J. and Johari, O. (1994). Electron spectroscopy and atomic force microscopy studies of DNA adsorption on mica. Scanning Microscopy, 8 (3), 471-480.
1994
Conference Publication
High-resolution SEM of biological macromolecular complexes
Wepf, R., Aebi, U., Bremer, A., Haider, M., Tittmann, P., Zach, J. and Gross, H. (1994). High-resolution SEM of biological macromolecular complexes.
1991
Journal Article
Platinum/iridium/carbon: a high‐resolution shadowing material for TEM, STM and SEM of biological macromolecular structures
Wepf, Roger, Amrein, Matthias, Bürkli, Urs and Gross, Heinz (1991). Platinum/iridium/carbon: a high‐resolution shadowing material for TEM, STM and SEM of biological macromolecular structures. Journal of Microscopy, 163 (1), 51-64. doi: 10.1111/j.1365-2818.1991.tb03159.x
1989
Journal Article
STM of freeze-dried and PtIrC-coated bacteriophage T4 polyheads
Aivirein, Matthias, Dürr, Roland, Winkler, Hanspeter, Travaglini, Giorgio, Wepf, Roger and Gross, Heinz (1989). STM of freeze-dried and PtIrC-coated bacteriophage T4 polyheads. Journal of Ultrastructure Research and Molecular Structure Research, 102 (2), 170-177. doi: 10.1016/0889-1605(89)90054-2
Funding
Current funding
Supervision
Availability
- Professor Roger Wepf is:
- Available for supervision
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Supervision history
Current supervision
-
Doctor Philosophy
Development of topical delivery system (TDS): Role of intrinsic and extrinsic factors on performance
Associate Advisor
Other advisors: Associate Professor Yousuf Mohammed
Media
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